JP2008506665A5 - - Google Patents
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- Publication number
- JP2008506665A5 JP2008506665A5 JP2007520813A JP2007520813A JP2008506665A5 JP 2008506665 A5 JP2008506665 A5 JP 2008506665A5 JP 2007520813 A JP2007520813 A JP 2007520813A JP 2007520813 A JP2007520813 A JP 2007520813A JP 2008506665 A5 JP2008506665 A5 JP 2008506665A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- kit according
- app
- antibody
- kit
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001413 amino acids Chemical class 0.000 claims 12
- 108010079054 Amyloid beta-Protein Precursor Proteins 0.000 claims 7
- 102000018430 Amyloid-beta precursor proteins Human genes 0.000 claims 7
- 108090000765 processed proteins & peptides Proteins 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 4
- 229940079593 drug Drugs 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 108010090849 Amyloid beta-Peptides Proteins 0.000 claims 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 claims 2
- 102000004878 Gelsolin Human genes 0.000 claims 2
- 108090001064 Gelsolin Proteins 0.000 claims 2
- 108010064539 amyloid beta-protein (1-42) Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000009919 sequestration Effects 0.000 claims 2
- 229960005486 vaccine Drugs 0.000 claims 2
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 claims 1
- 208000024827 Alzheimer disease Diseases 0.000 claims 1
- 102000013918 Apolipoproteins E Human genes 0.000 claims 1
- 108010025628 Apolipoproteins E Proteins 0.000 claims 1
- 108091023037 Aptamer Proteins 0.000 claims 1
- 150000008574 D-amino acids Chemical class 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 238000002617 apheresis Methods 0.000 claims 1
- -1 aromatic amino acid Chemical class 0.000 claims 1
- 102000023732 binding proteins Human genes 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 238000002648 combination therapy Methods 0.000 claims 1
- 150000002270 gangliosides Chemical class 0.000 claims 1
- 230000002209 hydrophobic effect Effects 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002510 pyrogen Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AT0118504A AT500483B1 (de) | 2004-07-13 | 2004-07-13 | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| ATA1185/2004 | 2004-07-13 | ||
| PCT/EP2005/053224 WO2006005706A2 (de) | 2004-07-13 | 2005-07-06 | Kombinationstherapie zur vorbeugung oder behandlung der alzheimer´schen erkrankung sowie kit hierfür |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013010868A Division JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008506665A JP2008506665A (ja) | 2008-03-06 |
| JP2008506665A5 true JP2008506665A5 (cg-RX-API-DMAC7.html) | 2008-08-14 |
| JP5642333B2 JP5642333B2 (ja) | 2014-12-17 |
Family
ID=35115768
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007520813A Expired - Fee Related JP5642333B2 (ja) | 2004-07-13 | 2005-07-06 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
| JP2013010868A Pending JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013010868A Pending JP2013116903A (ja) | 2004-07-13 | 2013-01-24 | アルツハイマー病の予防または治療のための併用療法およびそのキット |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US7935348B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1765388B8 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5642333B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR101158600B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN101022825B (cg-RX-API-DMAC7.html) |
| AT (1) | AT500483B1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005261687B8 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2577332C (cg-RX-API-DMAC7.html) |
| DK (1) | DK1765388T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2414872T3 (cg-RX-API-DMAC7.html) |
| PL (1) | PL1765388T3 (cg-RX-API-DMAC7.html) |
| PT (1) | PT1765388E (cg-RX-API-DMAC7.html) |
| TW (1) | TW200602072A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006005706A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003303198A1 (en) | 2002-12-19 | 2004-07-14 | New York University | Method for treating amyloid disease |
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| HRP20140240T4 (hr) * | 2005-11-30 | 2017-02-24 | Abbvie Inc. | Monoklonalna antitijela protiv amiloidnih beta proteina i njihova upotreba |
| US8691224B2 (en) | 2005-11-30 | 2014-04-08 | Abbvie Inc. | Anti-Aβ globulomer 5F7 antibodies |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| AR064501A1 (es) * | 2006-12-22 | 2009-04-08 | Genentech Inc | Antagonistas del dr6 (receptor de muerte 6) y usos de los mismos en el tratamiento de trastornos neurologicos |
| US8895004B2 (en) * | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| US8586706B2 (en) * | 2007-10-25 | 2013-11-19 | Kagoshima University | Peptide vaccine using mimic molecules of amyloid β peptide |
| ES2332846B1 (es) | 2007-10-26 | 2010-07-08 | Grifols, S.A. | Utilizacion de albumina humana terapeutica para la preparacion de un medicamento para el tratamiento de pacientes afectados por desordenes cognitivos. |
| AT506819B1 (de) * | 2008-06-12 | 2011-06-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzin zur behandlung von alzheimer-krankheit |
| AT506820B1 (de) * | 2008-06-12 | 2011-07-15 | Affiris Forschungs Und Entwicklungs Gmbh | Vakzine gegen alzheimer-krankheit |
| EP2320987A1 (en) * | 2008-07-29 | 2011-05-18 | Medtronic, Inc. | Apheresis of a target molecule from cerebrospinal fluid |
| AU2009313851A1 (en) * | 2008-11-13 | 2010-05-20 | Modgene, Llc | Modification of amyloid-beta load in non-brain tissue |
| CA2748561C (en) | 2008-12-22 | 2016-11-01 | Kaneka Corporation | A.beta. remover, a.beta. removing apparatus and a.beta. removal system |
| US20110033463A1 (en) * | 2009-08-06 | 2011-02-10 | Medtronic, Inc. | Apheresis, administration of agent, or combination thereof |
| US8987419B2 (en) | 2010-04-15 | 2015-03-24 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| US10112000B2 (en) | 2010-07-08 | 2018-10-30 | Asahi Kasei Medical Co., Ltd. | Method for reducing amyloid beta concentration in blood |
| EP3533803B1 (en) | 2010-08-14 | 2021-10-27 | AbbVie Inc. | Anti-amyloid-beta antibodies |
| US20120328605A1 (en) * | 2010-10-27 | 2012-12-27 | Daniel Larocque | Compositions and uses |
| PT2579042E (pt) | 2011-10-04 | 2014-09-09 | Affiris Ag | Método para detecção de anticorpos específicos para a numa amostra biológica. |
| CA2853961C (en) | 2011-11-01 | 2016-09-20 | Modgene, Llc | Compositions and methods for reduction of amyloid-beta load |
| WO2013140785A1 (ja) * | 2012-03-18 | 2013-09-26 | 国立大学法人九州大学 | 疾患サンプル分析装置、分析システム及び分析方法 |
| DE102012108598A1 (de) * | 2012-09-14 | 2014-04-10 | Forschungszentrum Jülich GmbH | Neue, von D3 abgeleitete D-enantiomere Peptide und deren Verwendung |
| DK2834643T3 (da) | 2012-04-05 | 2020-02-03 | Forschungszentrum Juelich Gmbh | Fremgangsmåde til behandling af blod, blodprodukter og organer |
| EP2834644B1 (de) | 2012-04-05 | 2019-08-21 | Forschungszentrum Jülich GmbH | Polymere, enthaltend multivalente amyloid-beta-bindende d-peptide und deren verwendung |
| KR101416954B1 (ko) * | 2012-09-12 | 2014-07-16 | 한양대학교 산학협력단 | 조혈세포 분화 유도 방법 |
| EP3116893B1 (en) * | 2014-03-11 | 2019-08-28 | Jacques Fantini | A chimeric peptide that interacts with cell membrane gangliosides |
| CN106466298A (zh) * | 2015-08-14 | 2017-03-01 | 上海交通大学医学院 | 一种单唾液酸四己糖神经节苷脂修饰的重组脂蛋白及其应用 |
| WO2017197253A2 (en) * | 2016-05-12 | 2017-11-16 | Ohio State Innovation Foundation | Peptides and methods for treating neurodegenerative disorders |
| US20200164008A1 (en) * | 2017-07-17 | 2020-05-28 | Spark Therapeutics, Inc. | Apheresis methods and uses |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| WO2020160156A2 (en) | 2019-01-30 | 2020-08-06 | Immutics, Inc. | Anti-gal3 antibodies and uses thereof |
| EP4157338A4 (en) | 2020-05-26 | 2024-11-13 | TrueBinding, Inc. | METHOD FOR TREATING INFLAMMATORY DISEASES BY GALECTIN-3 BLOCKING |
| CN115957324A (zh) * | 2021-10-12 | 2023-04-14 | 首都医科大学宣武医院 | 外周CLU作为靶点在降低脑Aβ中的应用 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476715A (en) | 1989-10-03 | 1995-12-19 | Fresenius Ag | Particulate adsorbent for the removal of biomacromolecules such as LDL and endotoxins from whole blood in extracorporeal circuits |
| AU691297B2 (en) | 1994-05-13 | 1998-05-14 | Miltenyi Biotec Gmbh | Sterile and pyrogen-free columns coupled to protein for binding and removal of substances from blood |
| ES2175325T3 (es) | 1997-06-18 | 2002-11-16 | Morse Tec Europe Srl | Rueda dentada con perfil de dientes mejorado para funcionamiento mas silencioso. |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| JP2002533169A (ja) | 1998-12-29 | 2002-10-08 | オキュロジックス コーポレイション | レオロジー的処置方法および関連するアフェレーシスシステム |
| PE20020574A1 (es) * | 2000-12-06 | 2002-07-02 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido amiloideo beta |
| WO2003000719A2 (en) * | 2001-06-20 | 2003-01-03 | Ramot At Tel Aviv University Ltd. | Multiple antigenic peptide displaying multiple copies of an epitope of plaque-forming polypeptide and methods of using same |
| WO2003051374A2 (en) | 2001-12-17 | 2003-06-26 | New York State Office Of Mental Health | SEQUESTRATION OF Aβ IN THE PERIPHERY IN THE ABSENCE OF IMMUNOMODULATING AGENT AS A THERAPEUTIC APPROACH FOR THE TREATMENT OR PREVENTION OF BETA-AMYLOID RELATED DISEASES |
| WO2004013172A2 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
| AU2003303198A1 (en) * | 2002-12-19 | 2004-07-14 | New York University | Method for treating amyloid disease |
| AT413945B (de) * | 2003-01-14 | 2006-07-15 | Mattner Frank Dr | Impfstoff für die alzheimer-krankheit |
| NZ567324A (en) * | 2003-02-01 | 2009-08-28 | Wyeth Corp | Active immunization to generate antibodies to soluble A-beta |
| AT413336B (de) | 2003-09-12 | 2006-02-15 | Mattner Frank Dr | Apherese-vorrichtung |
| US20050158306A1 (en) * | 2004-01-16 | 2005-07-21 | Halikas James A. | Treatment for neuro-degenerative disease by a blood cleansing system using monoclonal antibodies |
| AT413946B (de) | 2004-07-13 | 2006-07-15 | Mattner Frank Dr | Impfstoff gegen die alzheimer-krankheit |
| AT500483B1 (de) * | 2004-07-13 | 2006-01-15 | Mattner Frank Dr | Set zur vorbeugung oder behandlung der alzheimer'schen erkrankung |
| AT500835B1 (de) * | 2004-09-13 | 2007-12-15 | Affiris Forschungs & Entwicklungs Gmbh | Cholinestertransport-protein-mimotop als atherosklerose-medikament |
-
2004
- 2004-07-13 AT AT0118504A patent/AT500483B1/de not_active IP Right Cessation
-
2005
- 2005-06-17 TW TW094120199A patent/TW200602072A/zh not_active IP Right Cessation
- 2005-07-06 EP EP05767978.9A patent/EP1765388B8/de not_active Expired - Lifetime
- 2005-07-06 PT PT57679789T patent/PT1765388E/pt unknown
- 2005-07-06 CN CN200580023830.5A patent/CN101022825B/zh not_active Expired - Fee Related
- 2005-07-06 US US11/571,970 patent/US7935348B2/en not_active Expired - Fee Related
- 2005-07-06 CA CA2577332A patent/CA2577332C/en not_active Expired - Fee Related
- 2005-07-06 AU AU2005261687A patent/AU2005261687B8/en not_active Ceased
- 2005-07-06 JP JP2007520813A patent/JP5642333B2/ja not_active Expired - Fee Related
- 2005-07-06 ES ES05767978T patent/ES2414872T3/es not_active Expired - Lifetime
- 2005-07-06 WO PCT/EP2005/053224 patent/WO2006005706A2/de not_active Ceased
- 2005-07-06 PL PL05767978T patent/PL1765388T3/pl unknown
- 2005-07-06 DK DK05767978.9T patent/DK1765388T3/da active
- 2005-07-06 KR KR1020077002208A patent/KR101158600B1/ko not_active Expired - Fee Related
-
2011
- 2011-03-11 US US13/045,967 patent/US20110201987A1/en not_active Abandoned
-
2013
- 2013-01-24 JP JP2013010868A patent/JP2013116903A/ja active Pending
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