JP2008504826A5 - - Google Patents
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- Publication number
- JP2008504826A5 JP2008504826A5 JP2007519575A JP2007519575A JP2008504826A5 JP 2008504826 A5 JP2008504826 A5 JP 2008504826A5 JP 2007519575 A JP2007519575 A JP 2007519575A JP 2007519575 A JP2007519575 A JP 2007519575A JP 2008504826 A5 JP2008504826 A5 JP 2008504826A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- complementary
- hybridizing
- nucleotide
- specific extension
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 claims 19
- 125000003729 nucleotide group Chemical group 0.000 claims 19
- 108700028369 Alleles Proteins 0.000 claims 14
- 230000000295 complement effect Effects 0.000 claims 14
- 238000000034 method Methods 0.000 claims 13
- 239000011324 bead Substances 0.000 claims 4
- 239000007787 solid Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 108010001237 Cytochrome P-450 CYP2D6 Proteins 0.000 claims 3
- 102100021704 Cytochrome P450 2D6 Human genes 0.000 claims 3
- 238000012408 PCR amplification Methods 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 238000002493 microarray Methods 0.000 claims 2
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58360504P | 2004-06-30 | 2004-06-30 | |
| PCT/CA2005/001000 WO2006002526A1 (en) | 2004-06-30 | 2005-06-30 | Method of detecting mutations in the gene encoding cytochrome p450-2d6 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008504826A JP2008504826A (ja) | 2008-02-21 |
| JP2008504826A5 true JP2008504826A5 (enExample) | 2008-08-07 |
Family
ID=35782443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007519575A Pending JP2008504826A (ja) | 2004-06-30 | 2005-06-30 | チトクロムｐ４５０−２ｄ６をコードする遺伝子における変異を検出する方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090215637A1 (enExample) |
| EP (1) | EP1781811B1 (enExample) |
| JP (1) | JP2008504826A (enExample) |
| AT (1) | ATE471991T1 (enExample) |
| AU (1) | AU2005259787B2 (enExample) |
| CA (1) | CA2571823A1 (enExample) |
| DE (1) | DE602005021971D1 (enExample) |
| WO (1) | WO2006002526A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8688385B2 (en) * | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
| US20100105041A1 (en) * | 2006-12-14 | 2010-04-29 | Siemens Healthcare Diagnostics Inc. | Reagents and methods for detecting cyp2d6 polymorphisms |
| CN102686728B (zh) | 2009-06-29 | 2018-09-18 | 卢米耐克斯公司 | 具有发夹构象的嵌合引物及其使用方法 |
| CN104195229A (zh) * | 2014-07-24 | 2014-12-10 | 益善生物技术股份有限公司 | 表皮生长因子受体抑制剂类药物疗效相关基因表达检测液相芯片试剂盒 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4851331A (en) * | 1986-05-16 | 1989-07-25 | Allied Corporation | Method and kit for polynucleotide assay including primer-dependant DNA polymerase |
| GB9001181D0 (en) * | 1990-01-18 | 1990-03-21 | Imp Cancer Res Tech | Genetic assay |
| DE69126064T2 (de) * | 1990-06-22 | 1997-08-28 | Hoffmann La Roche | Nachweis von schwachen Metabolisierungsreagentien von Drogen |
| US5474796A (en) | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
| US6015880A (en) | 1994-03-16 | 2000-01-18 | California Institute Of Technology | Method and substrate for performing multiple sequential reactions on a matrix |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| GB9902971D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Assay |
| US6287778B1 (en) * | 1999-10-19 | 2001-09-11 | Affymetrix, Inc. | Allele detection using primer extension with sequence-coded identity tags |
| ATE333504T1 (de) * | 2000-01-31 | 2006-08-15 | Epidauros Biotechnologie Ag | Polymorphismen in der promoterregion des humanen cyp2d6 gens und deren diagnostische und therapeutische verwendung |
| JP2002119299A (ja) * | 2000-10-16 | 2002-04-23 | Internatl Reagents Corp | 遺伝子変異分析法 |
| EP2327794A3 (en) * | 2001-01-25 | 2011-09-14 | TM Bioscience Corporation | Polynucleotides for use as tags and tag complements, manufacture and use thereof |
| EP1373574A4 (en) * | 2001-03-30 | 2007-01-03 | Ge Healthcare Bio Sciences Ab | BIOPUCES ANALYSIS OF SIMPLE POLYMORPHISMS NUCL OTIDE |
| JP2005176601A (ja) * | 2001-12-06 | 2005-07-07 | Tsumura & Co | Ｃｙｐ２ｄ６変異遺伝子 |
| US20040096874A1 (en) * | 2002-04-11 | 2004-05-20 | Third Wave Technologies, Inc. | Characterization of CYP 2D6 genotypes |
| US20040091909A1 (en) * | 2002-07-05 | 2004-05-13 | Huang Doug Hui | High throughput cytochrome P450 genotyping |
| CA2571817A1 (en) * | 2004-06-30 | 2006-01-12 | Tm Bioscience Pgx, Inc. | Method of detecting mutations in the gene encoding cytochrome p450-2c9 |
| US20080248466A1 (en) * | 2004-07-30 | 2008-10-09 | Tm Bioscience Pgx Inc. | Method Of Detecting Mutations In The Gene Encoding Cytochrome P450-2C19 |
-
2005
- 2005-06-30 EP EP05761958A patent/EP1781811B1/en not_active Expired - Lifetime
- 2005-06-30 CA CA002571823A patent/CA2571823A1/en not_active Abandoned
- 2005-06-30 AU AU2005259787A patent/AU2005259787B2/en not_active Ceased
- 2005-06-30 US US11/631,197 patent/US20090215637A1/en not_active Abandoned
- 2005-06-30 DE DE602005021971T patent/DE602005021971D1/de not_active Expired - Lifetime
- 2005-06-30 WO PCT/CA2005/001000 patent/WO2006002526A1/en not_active Ceased
- 2005-06-30 JP JP2007519575A patent/JP2008504826A/ja active Pending
- 2005-06-30 AT AT05761958T patent/ATE471991T1/de not_active IP Right Cessation
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