DE602005021971D1 - Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen - Google Patents

Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen

Info

Publication number
DE602005021971D1
DE602005021971D1 DE602005021971T DE602005021971T DE602005021971D1 DE 602005021971 D1 DE602005021971 D1 DE 602005021971D1 DE 602005021971 T DE602005021971 T DE 602005021971T DE 602005021971 T DE602005021971 T DE 602005021971T DE 602005021971 D1 DE602005021971 D1 DE 602005021971D1
Authority
DE
Germany
Prior art keywords
cytochrom
procedure
detecting mutations
gen
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005021971T
Other languages
English (en)
Inventor
Frank Merante
James D Gordon
Susan Bortolin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Luminex Molecular Diagnostics Inc
Original Assignee
Luminex Molecular Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Luminex Molecular Diagnostics Inc filed Critical Luminex Molecular Diagnostics Inc
Publication of DE602005021971D1 publication Critical patent/DE602005021971D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Foundations (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
DE602005021971T 2004-06-30 2005-06-30 Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen Active DE602005021971D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58360504P 2004-06-30 2004-06-30
PCT/CA2005/001000 WO2006002526A1 (en) 2004-06-30 2005-06-30 Method of detecting mutations in the gene encoding cytochrome p450-2d6

Publications (1)

Publication Number Publication Date
DE602005021971D1 true DE602005021971D1 (de) 2010-08-05

Family

ID=35782443

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602005021971T Active DE602005021971D1 (de) 2004-06-30 2005-06-30 Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen

Country Status (8)

Country Link
US (1) US20090215637A1 (de)
EP (1) EP1781811B1 (de)
JP (1) JP2008504826A (de)
AT (1) ATE471991T1 (de)
AU (1) AU2005259787B2 (de)
CA (1) CA2571823A1 (de)
DE (1) DE602005021971D1 (de)
WO (1) WO2006002526A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8688385B2 (en) * 2003-02-20 2014-04-01 Mayo Foundation For Medical Education And Research Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype
WO2008076856A2 (en) * 2006-12-14 2008-06-26 Siemens Healthcare Diagnostics Inc. Reagents and methods for detecting cyp2d6 polymorphisms
US9587270B2 (en) 2009-06-29 2017-03-07 Luminex Corporation Chimeric primers with hairpin conformations and methods of using same
CN104195229A (zh) * 2014-07-24 2014-12-10 益善生物技术股份有限公司 表皮生长因子受体抑制剂类药物疗效相关基因表达检测液相芯片试剂盒

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4851331A (en) 1986-05-16 1989-07-25 Allied Corporation Method and kit for polynucleotide assay including primer-dependant DNA polymerase
GB9001181D0 (en) * 1990-01-18 1990-03-21 Imp Cancer Res Tech Genetic assay
DE69126064T2 (de) * 1990-06-22 1997-08-28 Hoffmann La Roche Nachweis von schwachen Metabolisierungsreagentien von Drogen
US5474796A (en) * 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
GB9902971D0 (en) 1999-02-11 1999-03-31 Zeneca Ltd Assay
US6287778B1 (en) * 1999-10-19 2001-09-11 Affymetrix, Inc. Allele detection using primer extension with sequence-coded identity tags
DE60121567T2 (de) * 2000-01-31 2007-07-05 Epidauros Biotechnologie Ag Polymorphismen in der promoterregion des humanen cyp2d6 gens und deren diagnostische und therapeutische verwendung
JP2002119299A (ja) * 2000-10-16 2002-04-23 Internatl Reagents Corp 遺伝子変異分析法
ATE546545T1 (de) * 2001-01-25 2012-03-15 Luminex Molecular Diagnostics Inc Polynukleotide zur verwendung als tags und tag komplemente, herstellung und verwendung derselben
US6986992B2 (en) * 2001-03-30 2006-01-17 Amersham Biosciences Ab P450 single nucleotide polymorphism biochip analysis
JP2005176601A (ja) * 2001-12-06 2005-07-07 Tsumura & Co Ｃｙｐ２ｄ６変異遺伝子
US20040096874A1 (en) * 2002-04-11 2004-05-20 Third Wave Technologies, Inc. Characterization of CYP 2D6 genotypes
US20040091909A1 (en) * 2002-07-05 2004-05-13 Huang Doug Hui High throughput cytochrome P450 genotyping
US20090099030A1 (en) * 2004-06-30 2009-04-16 Frank Merante Method of detecting mutations in the gene encoding cytochrome P450-2C9
WO2006010266A1 (en) * 2004-07-30 2006-02-02 Tm Bioscience Pgx, Inc. Et Al Method of detecting mutations in the gene encoding cytochrome p450-2c19

Also Published As

Publication number Publication date
US20090215637A1 (en) 2009-08-27
EP1781811B1 (de) 2010-06-23
AU2005259787A1 (en) 2006-01-12
EP1781811A1 (de) 2007-05-09
ATE471991T1 (de) 2010-07-15
CA2571823A1 (en) 2006-01-12
EP1781811A4 (de) 2008-02-13
JP2008504826A (ja) 2008-02-21
AU2005259787B2 (en) 2011-02-24
WO2006002526A1 (en) 2006-01-12

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