DE602005007874D1 - Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden - Google Patents

Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Info

Publication number
DE602005007874D1
DE602005007874D1 DE602005007874T DE602005007874T DE602005007874D1 DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1 DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 T DE602005007874 T DE 602005007874T DE 602005007874 D1 DE602005007874 D1 DE 602005007874D1
Authority
DE
Germany
Prior art keywords
present
encoding
reaction
decoding
coding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602005007874T
Other languages
English (en)
Inventor
Kai Qin Lao
Mark T Reed
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
Applera Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applera Corp filed Critical Applera Corp
Publication of DE602005007874D1 publication Critical patent/DE602005007874D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869Methods for sequencing
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6851Quantitative amplification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602005007874T 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden Active DE602005007874D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US55616304P 2004-03-24 2004-03-24
US55615704P 2004-03-24 2004-03-24
US55622404P 2004-03-24 2004-03-24
US55616204P 2004-03-24 2004-03-24
US63068104P 2004-11-24 2004-11-24
PCT/US2005/009882 WO2005094532A2 (en) 2004-03-24 2005-03-24 Encoding and decoding reactions for determining target polynucleotides

Publications (1)

Publication Number Publication Date
DE602005007874D1 true DE602005007874D1 (de) 2008-08-14

Family

ID=35064420

Family Applications (2)

Application Number Title Priority Date Filing Date
DE602005007874T Active DE602005007874D1 (de) 2004-03-24 2005-03-24 Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden
DE602005014453T Active DE602005014453D1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE602005014453T Active DE602005014453D1 (de) 2004-03-24 2005-03-24 Ligation und amplifikationsreaktionen zur bestimmung von zielmolekülen

Country Status (6)

Country Link
US (2) US7601821B2 (de)
EP (3) EP1727913B8 (de)
JP (2) JP2007530051A (de)
AT (2) ATE399884T1 (de)
DE (2) DE602005007874D1 (de)
WO (2) WO2005098040A2 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7153658B2 (en) * 2002-09-19 2006-12-26 Applera Corporation Methods and compositions for detecting targets
US7570443B2 (en) 2003-09-19 2009-08-04 Applied Biosystems, Llc Optical camera alignment
DE602005007874D1 (de) 2004-03-24 2008-08-14 Applera Corp Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden
US7427479B2 (en) * 2004-04-30 2008-09-23 Applera Corporation Methods and kits for identifying target nucleotides in mixed populations
WO2005108618A2 (en) * 2004-04-30 2005-11-17 Applera Corporation Methods and kits for methylation detection
US7575863B2 (en) 2004-05-28 2009-08-18 Applied Biosystems, Llc Methods, compositions, and kits comprising linker probes for quantifying polynucleotides
WO2006005055A2 (en) * 2004-06-30 2006-01-12 Applera Corporation Methods reaction mixtures and kits for ligating polynucleotides
JP2008513028A (ja) * 2004-09-21 2008-05-01 アプレラ コーポレイション マイクロRNA(miRNA)の二色リアルタイム/エンドポイント定量化
WO2007011903A2 (en) 2005-07-15 2007-01-25 Applera Corporation Analyzing messenger rna and micro rna in the same reaction mixture
CN101351542A (zh) * 2005-07-15 2009-01-21 阿普尔拉公司 液体加工装置和方法
US20070141593A1 (en) * 2005-08-22 2007-06-21 Lee Linda G Apparatus, system, and method using immiscible-fluid-discrete-volumes
WO2007025281A2 (en) * 2005-08-24 2007-03-01 Applera Corporation A method to quantify sirnas, mirnas and polymorphic mirnas
CA2651815A1 (en) * 2006-05-10 2007-11-22 Dxterity Diagnostics Detection of nucleic acid targets using chemically reactive oligonucleotide probes
US8597938B2 (en) * 2007-10-12 2013-12-03 Qiagen Sciences Llc System for providing control reactions for real time RT-PCR
US9157116B2 (en) * 2008-02-08 2015-10-13 Fluidigm Corporation Combinatorial amplification and detection of nucleic acids
CA2734868C (en) * 2008-08-26 2019-09-10 Fluidigm Corporation Assay methods for increased throughput of samples and/or targets
US8583380B2 (en) 2008-09-05 2013-11-12 Aueon, Inc. Methods for stratifying and annotating cancer drug treatment options
JP5608998B2 (ja) * 2009-03-31 2014-10-22 東洋紡株式会社 保存安定性に優れた核酸増幅検出試薬キット
JP2012531887A (ja) * 2009-04-01 2012-12-13 ディクステリティー ダイアグノーティクス インコーポレイテッド 化学的ライゲーション依存型プローブ増幅(clpa)
DK2414547T3 (da) 2009-04-02 2014-06-16 Fluidigm Corp Multiprimer-amplifikationsmetode til stregkodning af målnukleinsyrer
WO2011056866A2 (en) 2009-11-05 2011-05-12 Epicentre Technologies Corporation Methods and kits for 3'-end-tagging of rna
SG10201407883PA (en) * 2009-12-07 2015-01-29 Illumina Inc Multi-sample indexing for multiplex genotyping
WO2011100057A2 (en) * 2010-02-09 2011-08-18 Eugene Spier Methods and compositions for universal detection of nucleic acids
EP3572528A1 (de) 2010-09-24 2019-11-27 The Board of Trustees of the Leland Stanford Junior University Direkte erfassung, amplifikation und sequenzierung einer ziel-dna unter verwendung immobilisierter primer
US9353406B2 (en) * 2010-10-22 2016-05-31 Fluidigm Corporation Universal probe assay methods
US20120288857A1 (en) * 2011-02-03 2012-11-15 Fluidigm Corporation Multifunctional probe-primers
US20140170653A1 (en) 2011-04-15 2014-06-19 Life Technologies Corporation Chemical ligation
CN103635594B (zh) 2011-05-09 2018-02-13 富鲁达公司 基于探针的核酸检测
CN106434871B (zh) 2011-05-17 2020-08-18 德克斯特里蒂诊断公司 用于检测目标核酸的方法与组合物
CN103890245B (zh) 2011-05-20 2020-11-17 富鲁达公司 核酸编码反应
WO2013052124A2 (en) * 2011-10-03 2013-04-11 University Of Florida Research Foundation, Inc. Rapid and reliable detection of infectious agents
WO2013101902A2 (en) 2011-12-30 2013-07-04 University Of Washington, Through Its Center For Commercialization Chromophoric polymer dots with narrow-band emission
US10648030B2 (en) 2012-01-13 2020-05-12 Affymetrix, Inc. Methods of determining the presence or absence of a plurality of target polynucleotides in a sample
EP4361608A3 (de) 2012-02-03 2024-07-24 California Institute of Technology Signalkodierung und -dekodierung in multiplexierten biochemischen assays
SG11201404899VA (en) 2012-02-14 2014-10-30 Univ Cornell Method for relative quantification of nucleic acid sequence, expression, or copy changes, using combined nuclease, ligation, and polymerase reactions
EP2852682B1 (de) 2012-05-21 2017-10-04 Fluidigm Corporation Einzelpartikelanalyse von teilchenpopulationen
IN2015DN01609A (de) 2012-08-03 2015-07-03 California Inst Of Techn
US10011862B2 (en) 2013-03-14 2018-07-03 Cornell University Method for relative quantification of changes in DNA methylation, using combined nuclease, ligation, and polymerase reactions
WO2015153571A2 (en) 2014-04-01 2015-10-08 Cornell University Detection of dna methylation using combined nuclease ligation reactions
WO2015191777A2 (en) 2014-06-10 2015-12-17 Dxterity Diagnostics Incorporated Devices and methods for collecting and stabilizing biological samples
EP3204520B1 (de) 2014-10-08 2020-02-12 Cornell University Verfahren zur identifizierung und quantifizierung von nukleinsäureexpression, spleissvarianten, translokation, kopienzahl oder methylierungsänderungen
US11118216B2 (en) 2015-09-08 2021-09-14 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
WO2017044993A2 (en) * 2015-09-08 2017-03-16 Affymetrix, Inc. Nucleic acid analysis by joining barcoded polynucleotide probes
WO2017106777A1 (en) 2015-12-16 2017-06-22 Fluidigm Corporation High-level multiplex amplification
US10066263B2 (en) 2016-06-17 2018-09-04 California Institute Of Technology Nucleic acid reactions and related methods and compositions

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4988617A (en) * 1988-03-25 1991-01-29 California Institute Of Technology Method of detecting a nucleotide change in nucleic acids
US5494810A (en) * 1990-05-03 1996-02-27 Cornell Research Foundation, Inc. Thermostable ligase-mediated DNA amplifications system for the detection of genetic disease
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
WO1993020236A1 (en) * 1992-04-03 1993-10-14 Applied Biosystems, Inc. Probe composition and method
WO1996015271A1 (en) 1994-11-16 1996-05-23 Abbott Laboratories Multiplex ligations-dependent amplification
GB9609441D0 (en) * 1996-05-04 1996-07-10 Zeneca Ltd Process
EP0912761A4 (de) * 1996-05-29 2004-06-09 Cornell Res Foundation Inc Bestimmung von unterschieden in der nukleisäuresequenz mittels einer kombination von ligasebestimmung und polymerase-kettenreaktion
US7014994B1 (en) * 1999-03-19 2006-03-21 Cornell Research Foundation,Inc. Coupled polymerase chain reaction-restriction-endonuclease digestion-ligase detection reaction process
US6331393B1 (en) * 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
CA2398107C (en) 2000-01-28 2013-11-19 Althea Technologies, Inc. Methods for analysis of gene expression
AU2001265121A1 (en) * 2000-05-30 2001-12-11 Applera Corporation Methods for detecting target nucleic acids using coupled ligation and amplification
US6620586B2 (en) 2001-02-20 2003-09-16 Applied Gene Technologies, Inc. Methods and compositions for analyzing nucleic acids
US20030119004A1 (en) * 2001-12-05 2003-06-26 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
EP1319718A1 (de) 2001-12-14 2003-06-18 Keygene N.V. Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen
WO2003060163A2 (en) * 2001-12-28 2003-07-24 Keygene N.V. Discrimination and detection of target nucleotide sequences using mass spectrometry
US6960436B2 (en) * 2002-02-06 2005-11-01 Epigenomics Ag Quantitative methylation detection in DNA samples
US7176002B2 (en) * 2002-05-16 2007-02-13 Applera Corporation Universal-tagged oligonucleotide primers and methods of use
US7153658B2 (en) * 2002-09-19 2006-12-26 Applera Corporation Methods and compositions for detecting targets
CN1318606C (zh) * 2002-09-19 2007-05-30 阿普里拉股份有限公司 检测靶序列的方法和组合物
US20040235005A1 (en) * 2002-10-23 2004-11-25 Ernest Friedlander Methods and composition for detecting targets
US20040110134A1 (en) * 2002-12-05 2004-06-10 Wenz H. Michael Methods for quantitating nucleic acids using coupled ligation and amplification
WO2005026389A2 (en) 2003-08-29 2005-03-24 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Ligation-based method of analysis of single nucleotide polymorphisms on genomic dna
DE602005007874D1 (de) 2004-03-24 2008-08-14 Applera Corp Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden

Also Published As

Publication number Publication date
EP1730312B1 (de) 2008-07-02
ATE399884T1 (de) 2008-07-15
EP2161346A1 (de) 2010-03-10
ATE431433T1 (de) 2009-05-15
WO2005098040A2 (en) 2005-10-20
US20050260640A1 (en) 2005-11-24
WO2005098040A8 (en) 2005-12-01
EP1730312A2 (de) 2006-12-13
EP1727913B1 (de) 2009-05-13
WO2005094532A2 (en) 2005-10-13
EP1727913B8 (de) 2009-08-19
EP1727913A2 (de) 2006-12-06
DE602005014453D1 (de) 2009-06-25
US7601821B2 (en) 2009-10-13
US20050272071A1 (en) 2005-12-08
JP2007530051A (ja) 2007-11-01
US7604937B2 (en) 2009-10-20
JP2007530048A (ja) 2007-11-01
EP2161346B1 (de) 2013-06-19
WO2005094532A3 (en) 2005-12-22
WO2005098040A3 (en) 2006-03-23

Similar Documents

Publication Publication Date Title
ATE399884T1 (de) Codierungs- und decodierungsreaktionen zur bestimmung von target-polynukleotiden
DE60133111D1 (de) Verfahren zur erkennung und zum assay von nukleinsäuresequenzen
WO2006019407A3 (en) Method for detecting and quantifying rare mutations/polymorphisms
ATE534748T1 (de) Direkter snp-nachweis mit nichtamplifizierter dna
WO2005094532B1 (en) Encoding and decoding reactions for determining target polynucleotides
ATE455870T1 (de) Oligonukleotide zur schnellen bestimmung von mikrobieller dns/rns
Lee et al. Single-molecule visualization of ROS-induced DNA damage in large DNA molecules
WO2004044549A3 (en) Universal tag assay
JP2009519001A5 (de)
WO2005047543A3 (en) Ligation assay
JP2009106220A (ja) 基板上での等温増幅反応による標的塩基配列の捕捉及び検出方法
ATE414096T1 (de) Verfahren zum nachweis und zur quantifizierung von analyten in komplexen mischungen
ATE226983T1 (de) Gekoppeltes ampflikation- und ligationverfahren
TW200720441A (en) New labelling strategies for the sensitive detection of analytes
WO2005010199A3 (en) Invasive cleavage reaction with electrochemical readout
ATE377091T1 (de) Verfahren zur erkennung von nukleinsäuren
WO2002083839A3 (en) P450 single nucleotide polymorphism biochip analysis
WO2005003386A3 (en) Oligonucleotide ligation assay by detecting released pyrophosphate
GB2539675A (en) Reagents, kits and methods for molecular barcoding
Lee et al. Development of an electrochemical detection system for measuring DNA methylation levels using methyl CpG-binding protein and glucose dehydrogenase-fused zinc finger protein
Cho et al. Detection of mismatched DNAs via the binding affinity of MutS using a gold nanoparticle-based competitive colorimetric method
DE59914868D1 (de) DNA-Nachweis über einen Strangreassoziationskomplex
ATE290692T1 (de) Verfahren zur erkennung von verbindungen,die die wechselwirkung von rna und rna-bindungsproteinen beinflussen
Krieg et al. Fast Detection of Single Nucleotide Polymorphisms (SNPs) by Primer Elongation with Monitoring of Supercritical‐Angle Fluorescence
JPWO2020072829A5 (de)

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: APPLIED BIOSYSTEMS, LLC (N. D. GES. D. STAATES, US

8380 Miscellaneous part iii

Free format text: PFANDRECHT

8380 Miscellaneous part iii

Free format text: PFANDRECHT AUFGEHOBEN