ATE471991T1 - Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen - Google Patents
Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden genInfo
- Publication number
- ATE471991T1 ATE471991T1 AT05761958T AT05761958T ATE471991T1 AT E471991 T1 ATE471991 T1 AT E471991T1 AT 05761958 T AT05761958 T AT 05761958T AT 05761958 T AT05761958 T AT 05761958T AT E471991 T1 ATE471991 T1 AT E471991T1
- Authority
- AT
- Austria
- Prior art keywords
- cytochrome
- gene coding
- detecting mutations
- tagged
- aspe
- Prior art date
Links
- 108010001237 Cytochrome P-450 CYP2D6 Proteins 0.000 title abstract 2
- 102100021704 Cytochrome P450 2D6 Human genes 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000035772 mutation Effects 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 108700028369 Alleles Proteins 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000009396 hybridization Methods 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
- Foundations (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US58360504P | 2004-06-30 | 2004-06-30 | |
| PCT/CA2005/001000 WO2006002526A1 (en) | 2004-06-30 | 2005-06-30 | Method of detecting mutations in the gene encoding cytochrome p450-2d6 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE471991T1 true ATE471991T1 (de) | 2010-07-15 |
Family
ID=35782443
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05761958T ATE471991T1 (de) | 2004-06-30 | 2005-06-30 | Verfahren zum nachweis von mutationen im für cytochrom p450-2d6 codierenden gen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090215637A1 (enExample) |
| EP (1) | EP1781811B1 (enExample) |
| JP (1) | JP2008504826A (enExample) |
| AT (1) | ATE471991T1 (enExample) |
| AU (1) | AU2005259787B2 (enExample) |
| CA (1) | CA2571823A1 (enExample) |
| DE (1) | DE602005021971D1 (enExample) |
| WO (1) | WO2006002526A1 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8688385B2 (en) * | 2003-02-20 | 2014-04-01 | Mayo Foundation For Medical Education And Research | Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype |
| US20100105041A1 (en) * | 2006-12-14 | 2010-04-29 | Siemens Healthcare Diagnostics Inc. | Reagents and methods for detecting cyp2d6 polymorphisms |
| CN102686728B (zh) | 2009-06-29 | 2018-09-18 | 卢米耐克斯公司 | 具有发夹构象的嵌合引物及其使用方法 |
| CN104195229A (zh) * | 2014-07-24 | 2014-12-10 | 益善生物技术股份有限公司 | 表皮生长因子受体抑制剂类药物疗效相关基因表达检测液相芯片试剂盒 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4851331A (en) * | 1986-05-16 | 1989-07-25 | Allied Corporation | Method and kit for polynucleotide assay including primer-dependant DNA polymerase |
| GB9001181D0 (en) * | 1990-01-18 | 1990-03-21 | Imp Cancer Res Tech | Genetic assay |
| DE69126064T2 (de) * | 1990-06-22 | 1997-08-28 | Hoffmann La Roche | Nachweis von schwachen Metabolisierungsreagentien von Drogen |
| US5474796A (en) | 1991-09-04 | 1995-12-12 | Protogene Laboratories, Inc. | Method and apparatus for conducting an array of chemical reactions on a support surface |
| US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
| US6015880A (en) | 1994-03-16 | 2000-01-18 | California Institute Of Technology | Method and substrate for performing multiple sequential reactions on a matrix |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| GB9902971D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Assay |
| US6287778B1 (en) * | 1999-10-19 | 2001-09-11 | Affymetrix, Inc. | Allele detection using primer extension with sequence-coded identity tags |
| ATE333504T1 (de) * | 2000-01-31 | 2006-08-15 | Epidauros Biotechnologie Ag | Polymorphismen in der promoterregion des humanen cyp2d6 gens und deren diagnostische und therapeutische verwendung |
| JP2002119299A (ja) * | 2000-10-16 | 2002-04-23 | Internatl Reagents Corp | 遺伝子変異分析法 |
| EP2327794A3 (en) * | 2001-01-25 | 2011-09-14 | TM Bioscience Corporation | Polynucleotides for use as tags and tag complements, manufacture and use thereof |
| EP1373574A4 (en) * | 2001-03-30 | 2007-01-03 | Ge Healthcare Bio Sciences Ab | BIOPUCES ANALYSIS OF SIMPLE POLYMORPHISMS NUCL OTIDE |
| JP2005176601A (ja) * | 2001-12-06 | 2005-07-07 | Tsumura & Co | Ｃｙｐ２ｄ６変異遺伝子 |
| US20040096874A1 (en) * | 2002-04-11 | 2004-05-20 | Third Wave Technologies, Inc. | Characterization of CYP 2D6 genotypes |
| US20040091909A1 (en) * | 2002-07-05 | 2004-05-13 | Huang Doug Hui | High throughput cytochrome P450 genotyping |
| CA2571817A1 (en) * | 2004-06-30 | 2006-01-12 | Tm Bioscience Pgx, Inc. | Method of detecting mutations in the gene encoding cytochrome p450-2c9 |
| US20080248466A1 (en) * | 2004-07-30 | 2008-10-09 | Tm Bioscience Pgx Inc. | Method Of Detecting Mutations In The Gene Encoding Cytochrome P450-2C19 |
-
2005
- 2005-06-30 EP EP05761958A patent/EP1781811B1/en not_active Expired - Lifetime
- 2005-06-30 CA CA002571823A patent/CA2571823A1/en not_active Abandoned
- 2005-06-30 AU AU2005259787A patent/AU2005259787B2/en not_active Ceased
- 2005-06-30 US US11/631,197 patent/US20090215637A1/en not_active Abandoned
- 2005-06-30 DE DE602005021971T patent/DE602005021971D1/de not_active Expired - Lifetime
- 2005-06-30 WO PCT/CA2005/001000 patent/WO2006002526A1/en not_active Ceased
- 2005-06-30 JP JP2007519575A patent/JP2008504826A/ja active Pending
- 2005-06-30 AT AT05761958T patent/ATE471991T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1781811B1 (en) | 2010-06-23 |
| DE602005021971D1 (de) | 2010-08-05 |
| JP2008504826A (ja) | 2008-02-21 |
| EP1781811A4 (en) | 2008-02-13 |
| WO2006002526A1 (en) | 2006-01-12 |
| EP1781811A1 (en) | 2007-05-09 |
| AU2005259787B2 (en) | 2011-02-24 |
| CA2571823A1 (en) | 2006-01-12 |
| AU2005259787A1 (en) | 2006-01-12 |
| US20090215637A1 (en) | 2009-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |