JP2008500050A5 - - Google Patents
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- Publication number
- JP2008500050A5 JP2008500050A5 JP2007515256A JP2007515256A JP2008500050A5 JP 2008500050 A5 JP2008500050 A5 JP 2008500050A5 JP 2007515256 A JP2007515256 A JP 2007515256A JP 2007515256 A JP2007515256 A JP 2007515256A JP 2008500050 A5 JP2008500050 A5 JP 2008500050A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- orthogonal
- trna
- position corresponding
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57455404P | 2004-05-25 | 2004-05-25 | |
| US60204804P | 2004-08-16 | 2004-08-16 | |
| PCT/US2005/018168 WO2005116237A2 (en) | 2004-05-25 | 2005-05-24 | Site specific incorporation of heavy atom-containing unnatural amino acids into proteins for crystal structure determination |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008500050A JP2008500050A (ja) | 2008-01-10 |
| JP2008500050A5 true JP2008500050A5 (https=) | 2008-07-03 |
Family
ID=35451472
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007515256A Pending JP2008500050A (ja) | 2004-05-25 | 2005-05-24 | 結晶構造決定のための重原子含有非天然アミノ酸の部位特異的蛋白質組込み |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7399619B2 (https=) |
| EP (1) | EP1774018A2 (https=) |
| JP (1) | JP2008500050A (https=) |
| AU (1) | AU2005248392A1 (https=) |
| BR (1) | BRPI0511482A (https=) |
| CA (1) | CA2567624A1 (https=) |
| IL (1) | IL179211A0 (https=) |
| MX (1) | MXPA06013586A (https=) |
| WO (1) | WO2005116237A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7083970B2 (en) * | 2001-04-19 | 2006-08-01 | The Scripps Research Institute | Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs |
| MXPA05003978A (es) * | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Sintesis de glicoproteinas. |
| WO2004094593A2 (en) | 2003-04-17 | 2004-11-04 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| WO2005019415A2 (en) | 2003-07-07 | 2005-03-03 | The Scripps Research Institute | Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| US20080171317A1 (en) * | 2004-09-22 | 2008-07-17 | The Scripps Research Institute | Site-Specific Labeling of Proteins for Nmr Studies |
| EP1807515A4 (en) | 2004-10-27 | 2008-06-18 | Scripps Research Inst | Orthogonal translation components for the in vivo incorporation of unnatural amino acids |
| US8367588B2 (en) * | 2005-10-12 | 2013-02-05 | The Scripps Research Institute | Selective posttranslational modification of phage-displayed polypeptides |
| WO2007092475A2 (en) | 2006-02-06 | 2007-08-16 | Franklin And Marshall College | Site-specific incorporation of fluorinated amino acids into proteins |
| RU2467069C2 (ru) * | 2006-03-09 | 2012-11-20 | Зе Скрипс Ресеч Инститьют | Система экспрессии компонентов ортогональной трансляции в эубактериальной клетке-хозяине |
| US7960141B2 (en) * | 2006-03-09 | 2011-06-14 | The Scripps Research Institute | Systems for the expression of orthogonal translation components in eubacterial host cells |
| KR20080113226A (ko) | 2006-03-16 | 2008-12-29 | 더 스크립스 리서치 인스티튜트 | 비천연 아미노산 페닐셀레노시스테인을 함유하는 단백질의 유전자적으로 프로그램된 발현 |
| US7807411B2 (en) * | 2006-05-23 | 2010-10-05 | The Scripps Research Institute | Genetically encoded fluorescent coumarin amino acids |
| EP2052083B1 (en) * | 2006-09-21 | 2014-01-08 | The Scripps Research Institute | Genetically programmed expression of selectively sulfated proteins in eubacteria |
| JP2010506591A (ja) | 2006-10-18 | 2010-03-04 | ザ スクリップス リサーチ インスティテュート | 哺乳動物細胞中の蛋白質への非天然アミノ酸の遺伝的組込み |
| MX2010004464A (es) | 2007-10-25 | 2010-06-07 | Scripps Research Inst | Incorporacion genetica de 3-aminotirosina a reductasas. |
| US9150849B2 (en) | 2007-11-02 | 2015-10-06 | The Scripps Research Institute | Directed evolution using proteins comprising unnatural amino acids |
| WO2009059056A2 (en) * | 2007-11-02 | 2009-05-07 | The Scripps Research Institute | A genetically encoded boronate amino acid |
| AU2008335778B2 (en) | 2007-12-11 | 2014-04-10 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast Pichia pastoris |
| CA2710683A1 (en) | 2008-01-03 | 2009-07-16 | Verenium Corporation | Transferases and oxidoreductases, nucleic acids encoding them and methods for making and using them |
| CN101970005A (zh) * | 2008-02-08 | 2011-02-09 | 斯克利普斯研究院 | 用遗传编码的非天然氨基酸打破免疫耐受 |
| US20090197339A1 (en) * | 2008-12-10 | 2009-08-06 | The Scripps Research Institute | In vivo unnatural amino acid expression in the methylotrophic yeast pichia pastoris |
| CN102307905B (zh) | 2008-12-10 | 2015-11-25 | 斯克利普斯研究院 | 利用化学反应性非天然氨基酸产生载体-肽偶联物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7083970B2 (en) | 2001-04-19 | 2006-08-01 | The Scripps Research Institute | Methods and compositions for the production of orthogonal tRNA-aminoacyl tRNA synthetase pairs |
| ES2324608T3 (es) | 2002-10-16 | 2009-08-11 | The Scripps Research Institute | Incorporacion especifica de sitio de cetoaminoacidos en proteinas. |
| MXPA05003978A (es) | 2002-10-16 | 2005-06-22 | Scripps Research Inst | Sintesis de glicoproteinas. |
| WO2004058946A2 (en) | 2002-12-22 | 2004-07-15 | The Scripps Research Institute | Protein arrays |
| WO2004094593A2 (en) | 2003-04-17 | 2004-11-04 | The Scripps Research Institute | Expanding the eukaryotic genetic code |
| JP5275566B2 (ja) | 2003-06-18 | 2013-08-28 | ザ スクリプス リサーチ インスティチュート | 反応性非天然アミノ酸遺伝コード付加 |
| WO2005019415A2 (en) | 2003-07-07 | 2005-03-03 | The Scripps Research Institute | Compositions of orthogonal lysyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| US20060160175A1 (en) | 2003-07-07 | 2006-07-20 | The Scripps Research Institute | Compositions of orthogonal leucyl-trna and aminoacyl-trna synthetase pairs and uses thereof |
| WO2005007624A2 (en) | 2003-07-07 | 2005-01-27 | The Scripps Research Institute | Compositions of orthogonal glutamyl-trna and aminoacyl trna synthetase pairs and uses thereof |
| JP5657850B2 (ja) | 2003-10-14 | 2015-01-21 | ザ スクリプス リサーチ インスティテュート | 酸化還元機能性アミノ酸のタンパク質への部位特異的組み入れ |
| AU2004321117B2 (en) | 2003-12-18 | 2010-09-02 | The Scripps Research Institute | Selective incorporation of 5-hydroxytryptophan into proteins in mammalian cells |
-
2005
- 2005-05-24 AU AU2005248392A patent/AU2005248392A1/en not_active Abandoned
- 2005-05-24 EP EP05780072A patent/EP1774018A2/en not_active Withdrawn
- 2005-05-24 WO PCT/US2005/018168 patent/WO2005116237A2/en not_active Ceased
- 2005-05-24 BR BRPI0511482-9A patent/BRPI0511482A/pt not_active IP Right Cessation
- 2005-05-24 JP JP2007515256A patent/JP2008500050A/ja active Pending
- 2005-05-24 CA CA002567624A patent/CA2567624A1/en not_active Abandoned
- 2005-05-24 MX MXPA06013586A patent/MXPA06013586A/es unknown
- 2005-05-24 US US11/137,850 patent/US7399619B2/en not_active Expired - Fee Related
-
2006
- 2006-11-13 IL IL179211A patent/IL179211A0/en unknown
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