JP2007517053A5 - - Google Patents

Download PDF

Info

Publication number
JP2007517053A5
JP2007517053A5 JP2006547498A JP2006547498A JP2007517053A5 JP 2007517053 A5 JP2007517053 A5 JP 2007517053A5 JP 2006547498 A JP2006547498 A JP 2006547498A JP 2006547498 A JP2006547498 A JP 2006547498A JP 2007517053 A5 JP2007517053 A5 JP 2007517053A5
Authority
JP
Japan
Prior art keywords
route
dosage form
dosage
endodontic
effervescent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2006547498A
Other languages
English (en)
Other versions
JP2007517053A (ja
JP5244318B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2004/043702 external-priority patent/WO2005065318A2/en
Publication of JP2007517053A publication Critical patent/JP2007517053A/ja
Publication of JP2007517053A5 publication Critical patent/JP2007517053A5/ja
Application granted granted Critical
Publication of JP5244318B2 publication Critical patent/JP5244318B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Description

治療Aおよび治療B後の血清フェンタニル薬物動態パラメータの相加平均および標準偏差ならびに統計的比較を、以下の表にまとめる。
Figure 2007517053
治療C、D、およびE後の血清フェンタニルの薬物動態パラメータの相加平均および標準偏差を、以下の表にまとめる。
Figure 2007517053
治療A、C、D、およびEについてのp値を含む用量比例性の評価を、以下の表にまとめる。
Figure 2007517053
全治療後の血清フェンタニル薬物動態パラメータの相加平均および標準偏差を、以下の表にまとめる。
Figure 2007517053

Claims (2)

  1. 頬側投与経路、歯内投与経路、または舌下投与経路によって投与した場合、20%少ないアヘン薬の投与量で、グリコール酸デンプン、発泡性物質およびpH調整物質を含まない別の同一の処方物に匹敵するCmaxを有する、請求項1に記載の投薬形態。
  2. F1またはF2ブリスター包装に包装されている、請求項1または2に記載の投薬形態。
JP2006547498A 2003-12-31 2004-12-30 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法 Active JP5244318B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US53361903P 2003-12-31 2003-12-31
US60/533,619 2003-12-31
US61566504P 2004-10-04 2004-10-04
US61578504P 2004-10-04 2004-10-04
US60/615,785 2004-10-04
US60/615,665 2004-10-04
PCT/US2004/043702 WO2005065318A2 (en) 2003-12-31 2004-12-30 Effervescent oral opiate dosage form

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013024651A Division JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

Publications (3)

Publication Number Publication Date
JP2007517053A JP2007517053A (ja) 2007-06-28
JP2007517053A5 true JP2007517053A5 (ja) 2008-02-14
JP5244318B2 JP5244318B2 (ja) 2013-07-24

Family

ID=34753692

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2006547498A Active JP5244318B2 (ja) 2003-12-31 2004-12-30 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法
JP2013024651A Active JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013024651A Active JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

Country Status (16)

Country Link
US (2) US7862833B2 (ja)
EP (1) EP1708685B1 (ja)
JP (2) JP5244318B2 (ja)
KR (1) KR101212437B1 (ja)
AT (1) ATE500821T1 (ja)
AU (1) AU2004311879B2 (ja)
BR (1) BRPI0418213A (ja)
CA (1) CA2549642C (ja)
DE (1) DE602004031771D1 (ja)
HK (1) HK1100166A1 (ja)
IL (1) IL176452A (ja)
MX (1) MXPA06007453A (ja)
NO (1) NO338567B1 (ja)
NZ (1) NZ548215A (ja)
WO (1) WO2005065318A2 (ja)
ZA (1) ZA200606173B (ja)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6974590B2 (en) * 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US20030118645A1 (en) * 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
WO2005065319A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
US7858121B2 (en) 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
AU2004311879B2 (en) * 2003-12-31 2010-08-05 Cima Labs Inc. Effervescent oral opiate dosage form
US8865743B2 (en) 2006-01-06 2014-10-21 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8535714B2 (en) 2006-01-06 2013-09-17 Acelrx Pharmaceuticals, Inc. Small volume oral transmucosal dosage forms containing sufentanil for treatment of pain
US8357114B2 (en) 2006-01-06 2013-01-22 Acelrx Pharmaceuticals, Inc. Drug dispensing device with flexible push rod
US8753308B2 (en) 2006-01-06 2014-06-17 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US8252328B2 (en) * 2006-01-06 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8252329B2 (en) 2007-01-05 2012-08-28 Acelrx Pharmaceuticals, Inc. Bioadhesive drug formulations for oral transmucosal delivery
US8202535B2 (en) 2006-01-06 2012-06-19 Acelrx Pharmaceuticals, Inc. Small-volume oral transmucosal dosage forms
US9066847B2 (en) * 2007-01-05 2015-06-30 Aceirx Pharmaceuticals, Inc. Storage and dispensing devices for administration of oral transmucosal dosage forms
US9289583B2 (en) 2006-01-06 2016-03-22 Acelrx Pharmaceuticals, Inc. Methods for administering small volume oral transmucosal dosage forms using a dispensing device
US20070260491A1 (en) * 2006-05-08 2007-11-08 Pamela Palmer System for delivery and monitoring of administration of controlled substances
US20070299687A1 (en) * 2006-06-23 2007-12-27 Pamela Palmer Inpatient system for patient-controlled delivery of oral transmucosal medications dosed as needed
US20080090874A1 (en) * 2006-09-20 2008-04-17 Messina John C Jr Treatment of breakthrough pain in patients suffering from chronic low back pain
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
WO2008069921A2 (en) * 2006-12-01 2008-06-12 Cima Labs Inc. Oral transmucosal nicotine dosage form
US20080287494A1 (en) * 2007-04-24 2008-11-20 Cephalon, Inc. Transmucosal treatment methods in patients with mucositis
AU2008248228B2 (en) 2007-05-01 2012-10-18 Cephalon, Inc. Composition for transmucosal delivery of polypeptides
US8945592B2 (en) 2008-11-21 2015-02-03 Acelrx Pharmaceuticals, Inc. Sufentanil solid dosage forms comprising oxygen scavengers and methods of using the same
DK2442650T3 (en) 2009-06-12 2015-12-07 Cynapsus Therapeutics Inc sublingual apomorphine
NZ612686A (en) 2010-12-16 2015-11-27 Cynapsus Therapeutics Inc Sublingual films
CA2853764C (en) * 2011-11-22 2017-05-16 Watson Pharmaceuticals, Inc. Immediate release abuse deterrent tablet
PL2849730T3 (pl) 2012-05-02 2017-05-31 Orexo Ab Nowa kompozycja zawierająca alfentanyl do leczenia ostrego bólu
MX362838B (es) 2012-07-12 2019-02-19 SpecGx LLC Composiciones farmacéuticas de liberación prolongada para disuadir el abuso de opioides que comprenden un plastómero, un elastómero y un plastificante delicuescente.
JP5988936B2 (ja) * 2013-09-04 2016-09-07 富士フイルム株式会社 撥水膜、成膜方法、ノズルプレート、インクジェットヘッド、及びインクジェット記録装置
MX2017008428A (es) 2014-12-23 2018-03-23 Acelrx Pharmaceuticals Inc Sistemas, dispositivos y métodos para dispensar formas de dosificación transmucosa oral.
JP7211706B2 (ja) 2015-04-21 2023-01-24 サノヴィオン ファーマシュティカルズ インコーポレーテッド 口腔粘膜へのアポモルフィンの投与によるパーキンソン病の治療方法
US9943513B1 (en) 2015-10-07 2018-04-17 Banner Life Sciences Llc Opioid abuse deterrent dosage forms
US10335405B1 (en) 2016-05-04 2019-07-02 Patheon Softgels, Inc. Non-burst releasing pharmaceutical composition
NO20171457A1 (no) * 2016-12-20 2018-06-21 X Ing As Effervesent sugetablett
US10335375B2 (en) 2017-05-30 2019-07-02 Patheon Softgels, Inc. Anti-overingestion abuse deterrent compositions

Family Cites Families (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1262888A (en) 1917-02-20 1918-04-16 Albert Westlake Mouth-tablet.
US1263888A (en) 1918-01-10 1918-04-23 J T Vail Wave-motor.
US2887437A (en) * 1956-08-22 1959-05-19 Pfizer & Co C Palatable vitamin tablet containing an amino acid
US3131123A (en) 1959-03-13 1964-04-28 Lab Francais De Therapeutique Enteric tablets and manufacture thereof
US3042531A (en) * 1959-12-09 1962-07-03 Leslie Salt Company Method of making a compressed tablet
US3577490A (en) 1967-10-02 1971-05-04 Miles Lab Effervescent tablet and process for making same
GB1212704A (en) 1967-11-21 1970-11-18 Prodotti Antibiotici Spa Vaginal suppositories
US3888976A (en) 1972-09-21 1975-06-10 William P Mlkvy Zinc and strontium ion containing effervescent mouthwash tablet
NL7302521A (en) 1973-02-23 1974-08-27 Foaming, effervescent capsules - contg. therapeutic agents for rectal and vaginal use
US3962417A (en) 1974-03-27 1976-06-08 Howell Charles J Dentifrice
JPS5157813A (en) 1974-11-14 1976-05-20 Sankyo Co Ll dooba mataha sonojudotaiseizaino seiho
US3972995A (en) 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4126684A (en) * 1976-02-11 1978-11-21 Ciba-Geigy Corporation 4-amino-3-p-halophenylbutyric acids and their derivatives used in the control of narcotic abuse
US4147768A (en) 1976-09-13 1979-04-03 Interx Research Corporation Enteric coated digoxin and therapeutic use thereof
US4370160A (en) * 1978-06-27 1983-01-25 Dow Corning Corporation Process for preparing silicone microparticles
US4187286A (en) 1979-01-02 1980-02-05 G&W Laboratories, Inc. Contraceptive suppository
US4289751A (en) 1979-06-29 1981-09-15 Merck & Co., Inc. Effervescent enteric-coated formulation of soluble form of erythromycin and therapeutic use thereof
JPS58152809A (ja) 1982-03-05 1983-09-10 Eisai Co Ltd 安定な発泡性「膣」坐剤
US4443428A (en) 1982-06-21 1984-04-17 Euroceltique, S.A. Extended action controlled release compositions
US4503031A (en) 1982-12-17 1985-03-05 Glassman Jacob A Super-fast-starting-sustained release tablet
US4493848A (en) 1983-07-14 1985-01-15 The Procter & Gamble Company Compositions and methods useful for producing analgesia
US4599342A (en) 1984-01-16 1986-07-08 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
GB8410290D0 (en) 1984-04-19 1984-05-31 Callingham B A Pharmaceutical compositions
US4613497A (en) 1984-02-29 1986-09-23 Health Products Development, Inc. Dry, water-foamable pharmaceutical compositions
US4725427A (en) 1984-03-13 1988-02-16 Albion International, Inc. Effervescent vitamin-mineral granule preparation
US4863737A (en) 1985-05-01 1989-09-05 University Of Utah Compositions and methods of manufacture of compressed powder medicaments
GB8421226D0 (en) 1984-08-21 1984-09-26 Int Conferences Ab Tooth cleaning tablet
US4639368A (en) 1984-08-23 1987-01-27 Farmacon Research Corporation Chewing gum containing a medicament and taste maskers
GB8426152D0 (en) * 1984-10-16 1984-11-21 Reckitt & Colmann Prod Ltd Medicinal compositions
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
US4756710A (en) 1985-04-05 1988-07-12 Merck & Co., Inc. pH-Mediated drug delivery system
US4671953A (en) 1985-05-01 1987-06-09 University Of Utah Research Foundation Methods and compositions for noninvasive administration of sedatives, analgesics, and anesthetics
US5288497A (en) * 1985-05-01 1994-02-22 The University Of Utah Compositions of oral dissolvable medicaments
US5785989A (en) 1985-05-01 1998-07-28 University Utah Research Foundation Compositions and methods of manufacturing of oral dissolvable medicaments
US4687662A (en) 1985-08-30 1987-08-18 Warner-Lambert Company Therapeutic effervescent composition
US5053396A (en) 1985-08-27 1991-10-01 Blass David H Therapeutic composition
US4764375A (en) 1985-09-11 1988-08-16 Kv Pharmaceutical Company Sachet drug delivery system
IT1209667B (it) 1985-11-12 1989-08-30 Zambon Spa Composizione effeverscente adattivita' analgesica.
US4876039A (en) * 1986-11-04 1989-10-24 Dow Corning Corporation Process for preparing silicone microparticles cured by a Michael addition reaction
IE873172L (en) 1986-12-29 1988-06-29 Harvard College Continuous process for producing a comestible tablet
GB8724763D0 (en) 1987-10-22 1987-11-25 Aps Research Ltd Sustained-release formulations
US5234957A (en) * 1991-02-27 1993-08-10 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
FR2633181B1 (fr) * 1988-06-24 1992-01-10 Glaxo Lab Sa Composition pharmaceutique a base de ranitidine et son procede de preparation
GB8820327D0 (en) * 1988-08-26 1988-09-28 May & Baker Ltd New compositions of matter
US5004601A (en) * 1988-10-14 1991-04-02 Zetachron, Inc. Low-melting moldable pharmaceutical excipient and dosage forms prepared therewith
US5135752A (en) 1988-10-14 1992-08-04 Zetachron, Inc. Buccal dosage form
DE3838431A1 (de) 1988-11-12 1990-05-17 Bayer Ag Ibuprofen-brausezubereitungen
US5073374A (en) * 1988-11-30 1991-12-17 Schering Corporation Fast dissolving buccal tablet
US5002771A (en) 1989-02-06 1991-03-26 Rorer Pharmaceutical Corp. Calcitonin suppository formulations
GB8909793D0 (en) 1989-04-28 1989-06-14 Beecham Group Plc Pharmaceutical formulation
US5223264A (en) 1989-10-02 1993-06-29 Cima Labs, Inc. Pediatric effervescent dosage form
US5178878A (en) 1989-10-02 1993-01-12 Cima Labs, Inc. Effervescent dosage form with microparticles
IT1246382B (it) 1990-04-17 1994-11-18 Eurand Int Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon
US5102666A (en) 1990-09-11 1992-04-07 Oramed, Inc. Calcium polycarbophil controlled release composition and method
US5468504A (en) 1990-12-21 1995-11-21 Laboratoires Glaxo S.A. Effervescent pharmaceutical compositions
TW212139B (ja) 1991-04-15 1993-09-01 Yamanouchi Pharma Co Ltd
US5559096A (en) 1991-04-15 1996-09-24 Applied Microbiology, Inc. Pharmaceutical compositions against gastric disorders
US5464632C1 (en) 1991-07-22 2001-02-20 Prographarm Lab Rapidly disintegratable multiparticular tablet
IT1251114B (it) 1991-07-26 1995-05-04 Farcon Ag Forme farmaceutiche antivirali per applicazione vaginale
IT1253711B (it) 1991-12-17 1995-08-23 Alfa Wassermann Spa Formulazioni farmaceutiche vaginali contenenti rifaximin e loro uso nel trattamento delle infezioni vaginali
JP3069458B2 (ja) 1992-01-29 2000-07-24 武田薬品工業株式会社 口腔内崩壊型錠剤およびその製造法
US5503846A (en) 1993-03-17 1996-04-02 Cima Labs, Inc. Base coated acid particles and effervescent formulation incorporating same
US5851553A (en) 1993-09-10 1998-12-22 Fuisz Technologies, Ltd. Process and apparatus for making rapidly dissolving dosage units and product therefrom
US5635210A (en) * 1994-02-03 1997-06-03 The Board Of Regents Of The University Of Oklahoma Method of making a rapidly dissolving tablet
US5458879A (en) * 1994-03-03 1995-10-17 The Procter & Gamble Company Oral vehicle compositions
WO1995024172A1 (en) 1994-03-07 1995-09-14 Theratech, Inc. Drug-containing adhesive composite transdermal delivery device
CA2185803C (en) 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
IE940292A1 (en) 1994-04-06 1995-10-18 Elan Corp Plc Biodegradable microcapsules and method for their manufacture
JP3170139B2 (ja) 1994-04-08 2001-05-28 エスエス製薬株式会社 発泡性錠剤
EP0755244A1 (en) 1994-04-13 1997-01-29 Novartis AG Temporally controlled drug delivery systems
AU697456B2 (en) 1994-06-15 1998-10-08 Dumex-Alpharma A/S Pellets
US5958458A (en) 1994-06-15 1999-09-28 Dumex-Alpharma A/S Pharmaceutical multiple unit particulate formulation in the form of coated cores
GB9417524D0 (en) 1994-08-31 1994-10-19 Cortecs Ltd Pharmaceutical compositions
US5550861A (en) * 1994-09-27 1996-08-27 Novalink Technologies, Inc. Modular PCMCIA modem and pager
CA2160423A1 (en) 1994-11-02 1996-05-03 Hemant N. Joshi Salts of nefazodone having improved dissolution rates
FR2729858B1 (fr) 1995-01-30 1997-04-18 Mission Soc Civ Composition effervescente a base de polyvinylpyrrolidone iodee et utilisation pour la desinfection
FR2732217B1 (fr) 1995-03-29 1997-06-06 Hesnard Xavier Forme d'administration solide a usage oral
US5656284A (en) 1995-04-24 1997-08-12 Balkin; Michael S. Oral transmucosal delivery tablet and method of making it
GB9510830D0 (en) 1995-05-27 1995-07-19 Zeneca Ltd Proteins
US5607697A (en) 1995-06-07 1997-03-04 Cima Labs, Incorporated Taste masking microparticles for oral dosage forms
CA2218370C (en) 1995-07-31 2006-10-03 Gerhard Gergely Chewable tablet with effervescent action
GB9517062D0 (en) 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
WO1997017067A1 (en) 1995-11-06 1997-05-15 Somerset Pharmaceuticals, Inc. Sublingual and buccal administration of selegiline
GB9523136D0 (en) 1995-11-11 1996-01-10 Procter & Gamble Silicone-containing powders
GB2307857B (en) 1995-12-04 1999-01-27 Euro Celtique Sa An effervescent formulation
US5958455A (en) 1996-02-09 1999-09-28 Quadrant Holdings Cambridge Ltd Oral solid dosage forms, methods of making same and compositions thereof
DE19606151C2 (de) * 1996-02-20 1999-05-12 Losan Pharma Gmbh Ibuprofen-Brausezubereitung sowie Verfahren zur Herstellung derselben
US5646151A (en) 1996-03-08 1997-07-08 Adolor Corporation Kappa agonist compounds and pharmaceutical formulations thereof
US5853759A (en) 1996-05-17 1998-12-29 Merck & Co.. Inc. Effervescent alendronate formulation
AU712710B2 (en) 1996-05-17 1999-11-11 Merck Sharp & Dohme Corp. Effervescent bisphosphonate formulation
US5914129A (en) * 1996-07-23 1999-06-22 Mauskop; Alexander Analgesic composition for treatment of migraine headaches
US6071539A (en) 1996-09-20 2000-06-06 Ethypharm, Sa Effervescent granules and methods for their preparation
US6488961B1 (en) 1996-09-20 2002-12-03 Ethypharm, Inc. Effervescent granules and methods for their preparation
US6649186B1 (en) * 1996-09-20 2003-11-18 Ethypharm Effervescent granules and methods for their preparation
US20010006677A1 (en) 1996-10-29 2001-07-05 Mcginity James W. Effervescence polymeric film drug delivery system
DE69838393T2 (de) 1997-04-01 2008-01-17 Cima Labs Inc., Eden Prairie Blisterverpackung für tabletten
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
FR2766089B1 (fr) 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
ES2173364T5 (es) * 1997-10-27 2005-04-16 DR. GERGELY & CO. Composicion efervescente con extracto vegetal.
JP4372347B2 (ja) 1998-03-11 2009-11-25 あすか製薬株式会社 発泡性腸溶製剤
US20030118645A1 (en) 1998-04-29 2003-06-26 Pather S. Indiran Pharmaceutical compositions for rectal and vaginal administration
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US6200604B1 (en) * 1998-03-27 2001-03-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6576250B1 (en) 1998-03-27 2003-06-10 Cima Labs Inc. Pharmaceutical compositions for rectal and vaginal administration
US6350470B1 (en) 1998-04-29 2002-02-26 Cima Labs Inc. Effervescent drug delivery system for oral administration
DE19814257A1 (de) 1998-03-31 1999-10-07 Asta Medica Ag Brauseformulierungen
US6368625B1 (en) 1998-08-12 2002-04-09 Cima Labs Inc. Orally disintegrable tablet forming a viscous slurry
SE9803239D0 (sv) 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
SE9803240D0 (sv) 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
US6680071B1 (en) 1999-03-03 2004-01-20 R. P. Scherer Technologies, Inc. Opioid agonist in a fast dispersing dosage form
US6835194B2 (en) * 1999-03-18 2004-12-28 Durect Corporation Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners
US6210699B1 (en) * 1999-04-01 2001-04-03 Watson Pharmaceuticals, Inc. Oral transmucosal delivery of drugs or any other ingredients via the inner buccal cavity
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
US6262062B1 (en) * 2000-08-15 2001-07-17 Cpd, Llc Method of treating the syndrome of coronary heart disease risk factors in humans
WO2002045713A2 (en) * 2000-12-04 2002-06-13 Sepracor, Inc. Orally-bioavailable formulations of fentanyl and congeners thereof
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
US20030068356A1 (en) * 2001-07-10 2003-04-10 Pather S. Indiran Sequential drug delivery systems
EP1587514B3 (en) 2003-01-31 2011-06-22 Orexo AB A rapid-acting pharmaceutical composition
US20050042281A1 (en) * 2003-08-21 2005-02-24 Singh Nikhilesh N. Compositions for delivering therapeutic agents across the oral mucosa
US20070036853A1 (en) 2003-12-31 2007-02-15 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
AU2004311879B2 (en) * 2003-12-31 2010-08-05 Cima Labs Inc. Effervescent oral opiate dosage form
US7858121B2 (en) 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
WO2005065319A2 (en) * 2003-12-31 2005-07-21 Cima Labs Inc. Generally linear effervescent oral fentanyl dosage form and methods of administering
TWI387466B (zh) 2004-10-04 2013-03-01 Cima Labs Inc 一般線型起泡的口服吩坦尼(fentanyl)劑型及投藥方法
FR2883179B1 (fr) * 2005-03-18 2009-04-17 Ethypharm Sa Comprime enrobe
US20090263476A1 (en) * 2008-04-16 2009-10-22 Jobdevairakkam Christopher N Composition of Rapid Disintegrating Direct Compression Buccal Tablet

Similar Documents

Publication Publication Date Title
JP2007517053A5 (ja)
JP2013121983A5 (ja)
JP2013100347A5 (ja)
BRPI0418228B8 (pt) forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil
RS52831B (en) THIN BUPRENORPHINE TILES FOR DRUG REPLACEMENT THERAPY
AR078417A1 (es) Composiciones de pelicula sublingual y bucal
JP2005518433A5 (ja)
WO2007143676A3 (en) Epinephrine dosing regimens comprising buccal, lingual or sublingual and injectable dosage forms
JP2007512939A5 (ja)
JP2009536147A5 (ja)
NZ736048A (en) The use of inhibitors of bruton’s tyrosine kinase (btk)
JP2007517054A5 (ja)
BR112013032122A2 (pt) liberação modificada de 4-metil-3-[[4-(3-piridinil)-2-pirimidinil]amino]-n-[5-(4-metil-1h-imidazol-1-il)-3-(trifluorometil)fenil] benzamida solubilizada usando ácidos orgânicos
WO2006029036A3 (en) Combination therapy with glatiramer acetate and n-acetylcysteine for the treatment of multiple sclerosis
WO2004056337A3 (en) Oral dosage forms with therapeutically active agents in controlled release cores and immediate release gelatin capsule coats
NZ548215A (en) Effervescent oral opiate dosage form
JP2007508326A5 (ja)
JP2007238598A5 (ja)
HUP0401200A2 (hu) Terbinafint tartalmazó gyógyszerészeti összetételek és eljárás előállításukra
JP2014507475A5 (ja)
JP2018521007A5 (ja)
WO2007131070A3 (en) Compositions, dosage forms and methods of treating emesis
AR098347A2 (es) Uso de dosificación oral efervescente de fentanilo
BR0315482A (pt) Composições farmacêuticas e formas de dosagem para liberações bucal e sublingual da tizanidina e métodos de administração da tizanidina de forma sublingual ou bucal
TW200621312A (en) Oral solid dosage forms containing a low dose of estradiol