JP2007517053A5 - - Google Patents

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Publication number
JP2007517053A5
JP2007517053A5 JP2006547498A JP2006547498A JP2007517053A5 JP 2007517053 A5 JP2007517053 A5 JP 2007517053A5 JP 2006547498 A JP2006547498 A JP 2006547498A JP 2006547498 A JP2006547498 A JP 2006547498A JP 2007517053 A5 JP2007517053 A5 JP 2007517053A5
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Japan
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route
dosage form
dosage
endodontic
effervescent
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JP2006547498A
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JP2007517053A (ja
JP5244318B2 (ja
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Priority claimed from PCT/US2004/043702 external-priority patent/WO2005065318A2/en
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Publication of JP2007517053A5 publication Critical patent/JP2007517053A5/ja
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Description

治療Aおよび治療B後の血清フェンタニル薬物動態パラメータの相加平均および標準偏差ならびに統計的比較を、以下の表にまとめる。
Figure 2007517053
治療C、D、およびE後の血清フェンタニルの薬物動態パラメータの相加平均および標準偏差を、以下の表にまとめる。
Figure 2007517053
治療A、C、D、およびEについてのp値を含む用量比例性の評価を、以下の表にまとめる。
Figure 2007517053
全治療後の血清フェンタニル薬物動態パラメータの相加平均および標準偏差を、以下の表にまとめる。
Figure 2007517053

Claims (2)

  1. 頬側投与経路、歯内投与経路、または舌下投与経路によって投与した場合、20%少ないアヘン薬の投与量で、グリコール酸デンプン、発泡性物質およびpH調整物質を含まない別の同一の処方物に匹敵するCmaxを有する、請求項1に記載の投薬形態。
  2. F1またはF2ブリスター包装に包装されている、請求項1または2に記載の投薬形態。
JP2006547498A 2003-12-31 2004-12-30 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法 Active JP5244318B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US53361903P 2003-12-31 2003-12-31
US60/533,619 2003-12-31
US61578504P 2004-10-04 2004-10-04
US61566504P 2004-10-04 2004-10-04
US60/615,785 2004-10-04
US60/615,665 2004-10-04
PCT/US2004/043702 WO2005065318A2 (en) 2003-12-31 2004-12-30 Effervescent oral opiate dosage form

Related Child Applications (1)

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JP2013024651A Division JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

Publications (3)

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JP2007517053A JP2007517053A (ja) 2007-06-28
JP2007517053A5 true JP2007517053A5 (ja) 2008-02-14
JP5244318B2 JP5244318B2 (ja) 2013-07-24

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JP2006547498A Active JP5244318B2 (ja) 2003-12-31 2004-12-30 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法
JP2013024651A Active JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

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JP2013024651A Active JP5685611B2 (ja) 2003-12-31 2013-02-12 発泡性経口アヘン薬投薬形態およびアヘン薬の投与方法

Country Status (16)

Country Link
US (2) US7862833B2 (ja)
EP (1) EP1708685B1 (ja)
JP (2) JP5244318B2 (ja)
KR (1) KR101212437B1 (ja)
AT (1) ATE500821T1 (ja)
AU (1) AU2004311879B2 (ja)
BR (1) BRPI0418213A (ja)
CA (1) CA2549642C (ja)
DE (1) DE602004031771D1 (ja)
HK (1) HK1100166A1 (ja)
IL (1) IL176452A (ja)
MX (1) MXPA06007453A (ja)
NO (1) NO338567B1 (ja)
NZ (1) NZ548215A (ja)
WO (1) WO2005065318A2 (ja)
ZA (1) ZA200606173B (ja)

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