JP2007516937A5 - - Google Patents
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- Publication number
- JP2007516937A5 JP2007516937A5 JP2006515885A JP2006515885A JP2007516937A5 JP 2007516937 A5 JP2007516937 A5 JP 2007516937A5 JP 2006515885 A JP2006515885 A JP 2006515885A JP 2006515885 A JP2006515885 A JP 2006515885A JP 2007516937 A5 JP2007516937 A5 JP 2007516937A5
- Authority
- JP
- Japan
- Prior art keywords
- rutin
- medium
- hexadecanedioic acid
- reactor
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- QQHJDPROMQRDLA-UHFFFAOYSA-N hexadecanedioic acid Chemical compound OC(=O)CCCCCCCCCCCCCCC(O)=O QQHJDPROMQRDLA-UHFFFAOYSA-N 0.000 description 12
- 229960004555 rutoside Drugs 0.000 description 7
- JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 description 5
- 235000005493 rutin Nutrition 0.000 description 5
- IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 description 4
- FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 description 4
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 description 4
- ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000001963 growth medium Substances 0.000 description 3
- 239000002609 medium Substances 0.000 description 3
- 230000010261 cell growth Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- MSXVEPNJUHWQHW-UHFFFAOYSA-N 2-methylbutan-2-ol Chemical compound CCC(C)(C)O MSXVEPNJUHWQHW-UHFFFAOYSA-N 0.000 description 1
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 108010084311 Novozyme 435 Proteins 0.000 description 1
- 239000003855 balanced salt solution Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 108091092356 cellular DNA Proteins 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 210000004748 cultured cell Anatomy 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- XEYBRNLFEZDVAW-ARSRFYASSA-N dinoprostone Chemical compound CCCCC[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O XEYBRNLFEZDVAW-ARSRFYASSA-N 0.000 description 1
- 229960002986 dinoprostone Drugs 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 210000002510 keratinocyte Anatomy 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 239000002808 molecular sieve Substances 0.000 description 1
- 238000002953 preparative HPLC Methods 0.000 description 1
- XEYBRNLFEZDVAW-UHFFFAOYSA-N prostaglandin E2 Natural products CCCCCC(O)C=CC1C(O)CC(=O)C1CC=CCCCC(O)=O XEYBRNLFEZDVAW-UHFFFAOYSA-N 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 description 1
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03013899 | 2003-06-20 | ||
| PCT/EP2004/006281 WO2005000831A1 (en) | 2003-06-20 | 2004-06-11 | ESTERS OF FLAVONOIDS WITH ω-SUBSTITUTED C6-C22 FATTY ACIDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516937A JP2007516937A (ja) | 2007-06-28 |
| JP2007516937A5 true JP2007516937A5 (enExample) | 2007-08-09 |
Family
ID=33547596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515885A Withdrawn JP2007516937A (ja) | 2003-06-20 | 2004-06-11 | フラボノイドとω−置換Ｃ６〜Ｃ２２脂肪酸とのエステル |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20070184098A1 (enExample) |
| EP (1) | EP1636204A1 (enExample) |
| JP (1) | JP2007516937A (enExample) |
| KR (1) | KR20060082790A (enExample) |
| WO (1) | WO2005000831A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006290886A (ja) * | 2005-04-06 | 2006-10-26 | Engelhard Lyon Sa | 少なくとも１種のアウロンを適用することによる美容的脱色素沈着ケア方法 |
| JP4742340B2 (ja) * | 2005-06-14 | 2011-08-10 | 独立行政法人産業技術総合研究所 | 硫酸基含有糖化合物、それを用いるサーズウイルスまたはインフルエンザウイルスの検出 |
| KR100862957B1 (ko) * | 2007-04-03 | 2008-10-13 | 바이오스펙트럼 주식회사 | 히페린을 유효성분으로 포함하는 피부주름 개선용 조성물 |
| FR2919501B1 (fr) * | 2007-08-02 | 2010-12-31 | Oreal | Utilisation d'hesperidine ou de l'un de ses derives pour la prevention et/ou le traitement des peaux relachees |
| FR2923718B1 (fr) * | 2007-11-15 | 2009-12-18 | Caudalie | Compositions de derives polyphenoliques flavonoidiques et leurs applications pour lutter contre les pathologies et le vieillissement des organismes vivants |
| AU2010217238B2 (en) * | 2009-02-27 | 2014-03-06 | Council Of Scientific & Industrial Research | A controlled release micro-capsule for osteogenic action |
| JP5854592B2 (ja) * | 2010-11-09 | 2016-02-09 | 丸善製薬株式会社 | 抗酸化剤及び抗炎症剤 |
| JP6170273B2 (ja) * | 2010-11-09 | 2017-07-26 | 丸善製薬株式会社 | 抗老化剤及び老化防止用皮膚外用剤 |
| KR101344487B1 (ko) * | 2012-01-18 | 2013-12-31 | 경희대학교 산학협력단 | 프루네틴 또는 이의 약학적으로 허용되는 염을 유효성분으로 함유하는 염증, 패혈증 또는 패혈성 쇼크의 예방 및 치료용 약학적 조성물 |
| JP2015193550A (ja) * | 2014-03-31 | 2015-11-05 | ホーユー株式会社 | 毛包ケラチノサイト幹細胞のｄｎａ損傷抑制剤 |
| JP6441052B2 (ja) * | 2014-12-05 | 2018-12-19 | 東洋精糖株式会社 | フラボノイド配糖体エステル、該フラボノイド配糖体エステルを含む抗菌剤、抗酸化剤および抗炎症剤 |
| US10899727B2 (en) | 2016-04-11 | 2021-01-26 | Middle Tennessee State University | Therapeutic aurones |
| CN106146581B (zh) * | 2016-06-24 | 2018-07-24 | 南京中医药大学 | 一种具有抗肿瘤活性和抗炎活性的醌式查尔酮与黄酮醇结合物及其制备方法和应用 |
| CN107164423B (zh) | 2017-05-27 | 2021-02-19 | 华南理工大学 | 一种全细胞催化制备曲克芦丁酯的方法 |
| JP7064675B2 (ja) * | 2018-02-23 | 2022-05-11 | 国立大学法人佐賀大学 | 乳化組成物およびその用途 |
| CN111304265B (zh) * | 2020-02-25 | 2021-03-02 | 暨南大学 | 一种油溶性黑豆皮花色苷酰化产物及其制备方法 |
| WO2023150072A1 (en) * | 2022-02-01 | 2023-08-10 | Sinclair David A | Compositions and methods for the preservation of plant matter |
| EP4293034A1 (en) * | 2022-06-17 | 2023-12-20 | Consejo Superior de Investigaciones Científicas (CSIC) | A novel acylated derivate of phloretin and its use as antioxidant |
| CN115490741B (zh) * | 2022-10-08 | 2025-02-11 | 合肥工业大学 | 一种异槲皮苷酯类二联体及其制备方法和用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4255336A (en) * | 1977-11-25 | 1981-03-10 | Ciba-Geigy Corporation | Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01 |
| NZ193316A (en) * | 1979-04-10 | 1984-07-31 | Hoffmann La Roche | 3-alkoxyflavone derivatives and pharmaceutical compositions |
| FR2706478B1 (fr) * | 1993-06-14 | 1995-09-08 | Ovi Sa | Compositions de dérivés phénoliques, leur préparation et leurs applications comme anti-oxydants. |
| FR2715582B1 (fr) * | 1994-02-02 | 1996-03-15 | Centre Nat Rech Scient | Microcapsules à paroi de flavonoïde réticulée et compositions en contenant. |
| FR2778663B1 (fr) * | 1998-05-15 | 2001-05-18 | Coletica | Nouveaux esters de flavonoides,leur utilisation en cosmetique, dermopharmacie, en pharmacie et en agro-alimentaire |
| WO1999063995A1 (en) * | 1998-06-12 | 1999-12-16 | Vyrex Corporation | Isoflavone derivatives |
| US20030170186A1 (en) * | 2000-04-18 | 2003-09-11 | Bernadette Geers | Novel flavone glycoside derivatives for use in cosmetics, pharmaceuticals and nutrition |
| DE10019235A1 (de) * | 2000-04-18 | 2001-10-31 | Henkel Kgaa | Neue Flavonglykosid-Derivate für den Einsatz in Kosmetika, Pharmazeutika und Ernährung |
| DE10056400A1 (de) * | 2000-11-14 | 2002-05-23 | Merck Patent Gmbh | Galenische Formulierung |
| EP1363594B1 (de) * | 2001-03-02 | 2007-11-21 | MERCK PATENT GmbH | Kosmetische formulierung enthaltend flavonoid-derivate |
| EP1426445A1 (de) * | 2002-12-03 | 2004-06-09 | Cognis France S.A. | Herstellung von Flavonoidderivaten |
-
2004
- 2004-06-11 WO PCT/EP2004/006281 patent/WO2005000831A1/en not_active Ceased
- 2004-06-11 KR KR1020057024472A patent/KR20060082790A/ko not_active Withdrawn
- 2004-06-11 JP JP2006515885A patent/JP2007516937A/ja not_active Withdrawn
- 2004-06-11 US US10/561,551 patent/US20070184098A1/en not_active Abandoned
- 2004-06-11 EP EP04739782A patent/EP1636204A1/en not_active Withdrawn
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