JP2007516937A - フラボノイドとω−置換Ｃ６〜Ｃ２２脂肪酸とのエステル - Google Patents
フラボノイドとω−置換Ｃ６〜Ｃ２２脂肪酸とのエステル Download PDFInfo
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- JP2007516937A JP2007516937A JP2006515885A JP2006515885A JP2007516937A JP 2007516937 A JP2007516937 A JP 2007516937A JP 2006515885 A JP2006515885 A JP 2006515885A JP 2006515885 A JP2006515885 A JP 2006515885A JP 2007516937 A JP2007516937 A JP 2007516937A
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- flavonoid
- acid
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- esters
- saturated
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- OVSQVDMCBVZWGM-DTGCRPNFSA-N quercetin 3-O-beta-D-galactopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-DTGCRPNFSA-N 0.000 description 1
- OVSQVDMCBVZWGM-QSOFNFLRSA-N quercetin 3-O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OVSQVDMCBVZWGM-QSOFNFLRSA-N 0.000 description 1
- OEKUVLQNKPXSOY-UHFFFAOYSA-N quercetin 3-O-beta-D-glucopyranosyl(1->3)-alpha-L-rhamnopyranosyl(1->6)-beta-d-galactopyranoside Natural products OC1C(O)C(C(O)C)OC1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OEKUVLQNKPXSOY-UHFFFAOYSA-N 0.000 description 1
- QPHXPNUXTNHJOF-UHFFFAOYSA-N quercetin-7-O-beta-L-rhamnopyranoside Natural products OC1C(O)C(O)C(C)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 QPHXPNUXTNHJOF-UHFFFAOYSA-N 0.000 description 1
- BBFYUPYFXSSMNV-UHFFFAOYSA-N quercetin-7-o-galactoside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC(O)=C2C(=O)C(O)=C(C=3C=C(O)C(O)=CC=3)OC2=C1 BBFYUPYFXSSMNV-UHFFFAOYSA-N 0.000 description 1
- OXGUCUVFOIWWQJ-HQBVPOQASA-N quercitrin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC1=C(C=2C=C(O)C(O)=CC=2)OC2=CC(O)=CC(O)=C2C1=O OXGUCUVFOIWWQJ-HQBVPOQASA-N 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 230000035806 respiratory chain Effects 0.000 description 1
- JGUZGNYPMHHYRK-UHFFFAOYSA-N rhamnetin Chemical compound C=1C(OC)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 JGUZGNYPMHHYRK-UHFFFAOYSA-N 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- FWYIBGHGBOVPNL-UHFFFAOYSA-N scopoletin Natural products COC=1C=C2C=CC(OC2=C(C1)O)=O FWYIBGHGBOVPNL-UHFFFAOYSA-N 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 230000037380 skin damage Effects 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 230000037394 skin elasticity Effects 0.000 description 1
- 238000000638 solvent extraction Methods 0.000 description 1
- GSZUGBAEBARHAW-UHFFFAOYSA-N sophoraflavone B Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(C=2OC3=CC(O)=CC=C3C(=O)C=2)C=C1 GSZUGBAEBARHAW-UHFFFAOYSA-N 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 150000003460 sulfonic acids Chemical class 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- 150000003512 tertiary amines Chemical class 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000001256 tonic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- ORHBXUUXSCNDEV-UHFFFAOYSA-N umbelliferone Chemical compound C1=CC(=O)OC2=CC(O)=CC=C21 ORHBXUUXSCNDEV-UHFFFAOYSA-N 0.000 description 1
- HFTAFOQKODTIJY-UHFFFAOYSA-N umbelliferone Natural products Cc1cc2C=CC(=O)Oc2cc1OCC=CC(C)(C)O HFTAFOQKODTIJY-UHFFFAOYSA-N 0.000 description 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/602—Glycosides, e.g. rutin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03013899 | 2003-06-20 | ||
| PCT/EP2004/006281 WO2005000831A1 (en) | 2003-06-20 | 2004-06-11 | ESTERS OF FLAVONOIDS WITH ω-SUBSTITUTED C6-C22 FATTY ACIDS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2007516937A true JP2007516937A (ja) | 2007-06-28 |
| JP2007516937A5 JP2007516937A5 (enExample) | 2007-08-09 |
Family
ID=33547596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006515885A Withdrawn JP2007516937A (ja) | 2003-06-20 | 2004-06-11 | フラボノイドとω−置換Ｃ６〜Ｃ２２脂肪酸とのエステル |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20070184098A1 (enExample) |
| EP (1) | EP1636204A1 (enExample) |
| JP (1) | JP2007516937A (enExample) |
| KR (1) | KR20060082790A (enExample) |
| WO (1) | WO2005000831A1 (enExample) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012102040A (ja) * | 2010-11-09 | 2012-05-31 | Maruzen Pharmaceut Co Ltd | 抗老化剤及び老化防止用皮膚外用剤 |
| JP2012102041A (ja) * | 2010-11-09 | 2012-05-31 | Maruzen Pharmaceut Co Ltd | 抗酸化剤及び抗炎症剤 |
| JP2015193550A (ja) * | 2014-03-31 | 2015-11-05 | ホーユー株式会社 | 毛包ケラチノサイト幹細胞のｄｎａ損傷抑制剤 |
| JP2016108272A (ja) * | 2014-12-05 | 2016-06-20 | 東洋精糖株式会社 | フラボノイド配糖体エステル、該フラボノイド配糖体エステルを含む抗菌剤、抗酸化剤および抗炎症剤 |
| JP2019141825A (ja) * | 2018-02-23 | 2019-08-29 | 国立大学法人佐賀大学 | 乳化組成物およびその用途 |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006290886A (ja) * | 2005-04-06 | 2006-10-26 | Engelhard Lyon Sa | 少なくとも１種のアウロンを適用することによる美容的脱色素沈着ケア方法 |
| JP4742340B2 (ja) * | 2005-06-14 | 2011-08-10 | 独立行政法人産業技術総合研究所 | 硫酸基含有糖化合物、それを用いるサーズウイルスまたはインフルエンザウイルスの検出 |
| KR100862957B1 (ko) * | 2007-04-03 | 2008-10-13 | 바이오스펙트럼 주식회사 | 히페린을 유효성분으로 포함하는 피부주름 개선용 조성물 |
| FR2919501B1 (fr) * | 2007-08-02 | 2010-12-31 | Oreal | Utilisation d'hesperidine ou de l'un de ses derives pour la prevention et/ou le traitement des peaux relachees |
| FR2923718B1 (fr) * | 2007-11-15 | 2009-12-18 | Caudalie | Compositions de derives polyphenoliques flavonoidiques et leurs applications pour lutter contre les pathologies et le vieillissement des organismes vivants |
| WO2010097814A2 (en) * | 2009-02-27 | 2010-09-02 | Council Of Scientific & Industrial Research | A controlled release micro-capsule for osteogenic action |
| KR101344487B1 (ko) * | 2012-01-18 | 2013-12-31 | 경희대학교 산학협력단 | 프루네틴 또는 이의 약학적으로 허용되는 염을 유효성분으로 함유하는 염증, 패혈증 또는 패혈성 쇼크의 예방 및 치료용 약학적 조성물 |
| EP3442520A4 (en) | 2016-04-11 | 2020-04-22 | Middle Tennessee State University | THERAPEUTIC AURONES |
| CN106146581B (zh) * | 2016-06-24 | 2018-07-24 | 南京中医药大学 | 一种具有抗肿瘤活性和抗炎活性的醌式查尔酮与黄酮醇结合物及其制备方法和应用 |
| CN107164423B (zh) * | 2017-05-27 | 2021-02-19 | 华南理工大学 | 一种全细胞催化制备曲克芦丁酯的方法 |
| CN111304265B (zh) * | 2020-02-25 | 2021-03-02 | 暨南大学 | 一种油溶性黑豆皮花色苷酰化产物及其制备方法 |
| WO2023150072A1 (en) * | 2022-02-01 | 2023-08-10 | Sinclair David A | Compositions and methods for the preservation of plant matter |
| EP4293034A1 (en) * | 2022-06-17 | 2023-12-20 | Consejo Superior de Investigaciones Científicas (CSIC) | A novel acylated derivate of phloretin and its use as antioxidant |
| CN115490741B (zh) * | 2022-10-08 | 2025-02-11 | 合肥工业大学 | 一种异槲皮苷酯类二联体及其制备方法和用途 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4255336A (en) * | 1977-11-25 | 1981-03-10 | Ciba-Geigy Corporation | Process for the preparation of O-substituted derivatives of (+)-cyanidan-3-01 |
| NZ193316A (en) * | 1979-04-10 | 1984-07-31 | Hoffmann La Roche | 3-alkoxyflavone derivatives and pharmaceutical compositions |
| FR2706478B1 (fr) * | 1993-06-14 | 1995-09-08 | Ovi Sa | Compositions de dérivés phénoliques, leur préparation et leurs applications comme anti-oxydants. |
| FR2715582B1 (fr) * | 1994-02-02 | 1996-03-15 | Centre Nat Rech Scient | Microcapsules à paroi de flavonoïde réticulée et compositions en contenant. |
| FR2778663B1 (fr) * | 1998-05-15 | 2001-05-18 | Coletica | Nouveaux esters de flavonoides,leur utilisation en cosmetique, dermopharmacie, en pharmacie et en agro-alimentaire |
| AU4435199A (en) * | 1998-06-12 | 1999-12-30 | Vyrex Corporation | Isoflavone derivatives |
| US20030170186A1 (en) * | 2000-04-18 | 2003-09-11 | Bernadette Geers | Novel flavone glycoside derivatives for use in cosmetics, pharmaceuticals and nutrition |
| DE10019235A1 (de) * | 2000-04-18 | 2001-10-31 | Henkel Kgaa | Neue Flavonglykosid-Derivate für den Einsatz in Kosmetika, Pharmazeutika und Ernährung |
| DE10056400A1 (de) * | 2000-11-14 | 2002-05-23 | Merck Patent Gmbh | Galenische Formulierung |
| US20040081675A1 (en) * | 2001-03-02 | 2004-04-29 | Corinna Wirth | Cosmetic formulations containing flavonoid derivatives |
| EP1426445A1 (de) * | 2002-12-03 | 2004-06-09 | Cognis France S.A. | Herstellung von Flavonoidderivaten |
-
2004
- 2004-06-11 JP JP2006515885A patent/JP2007516937A/ja not_active Withdrawn
- 2004-06-11 WO PCT/EP2004/006281 patent/WO2005000831A1/en not_active Ceased
- 2004-06-11 US US10/561,551 patent/US20070184098A1/en not_active Abandoned
- 2004-06-11 EP EP04739782A patent/EP1636204A1/en not_active Withdrawn
- 2004-06-11 KR KR1020057024472A patent/KR20060082790A/ko not_active Withdrawn
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012102040A (ja) * | 2010-11-09 | 2012-05-31 | Maruzen Pharmaceut Co Ltd | 抗老化剤及び老化防止用皮膚外用剤 |
| JP2012102041A (ja) * | 2010-11-09 | 2012-05-31 | Maruzen Pharmaceut Co Ltd | 抗酸化剤及び抗炎症剤 |
| JP2015193550A (ja) * | 2014-03-31 | 2015-11-05 | ホーユー株式会社 | 毛包ケラチノサイト幹細胞のｄｎａ損傷抑制剤 |
| JP2016108272A (ja) * | 2014-12-05 | 2016-06-20 | 東洋精糖株式会社 | フラボノイド配糖体エステル、該フラボノイド配糖体エステルを含む抗菌剤、抗酸化剤および抗炎症剤 |
| JP2019141825A (ja) * | 2018-02-23 | 2019-08-29 | 国立大学法人佐賀大学 | 乳化組成物およびその用途 |
| JP7064675B2 (ja) | 2018-02-23 | 2022-05-11 | 国立大学法人佐賀大学 | 乳化組成物およびその用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1636204A1 (en) | 2006-03-22 |
| US20070184098A1 (en) | 2007-08-09 |
| KR20060082790A (ko) | 2006-07-19 |
| WO2005000831A1 (en) | 2005-01-06 |
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