JP2007516721A5 - - Google Patents
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- Publication number
- JP2007516721A5 JP2007516721A5 JP2006546873A JP2006546873A JP2007516721A5 JP 2007516721 A5 JP2007516721 A5 JP 2007516721A5 JP 2006546873 A JP2006546873 A JP 2006546873A JP 2006546873 A JP2006546873 A JP 2006546873A JP 2007516721 A5 JP2007516721 A5 JP 2007516721A5
- Authority
- JP
- Japan
- Prior art keywords
- virion
- pneumovirus
- host cell
- protein
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002845 virion Anatomy 0.000 claims 19
- 108090000623 proteins and genes Proteins 0.000 claims 17
- 241000711902 Pneumovirus Species 0.000 claims 12
- 238000000034 method Methods 0.000 claims 11
- 102000004169 proteins and genes Human genes 0.000 claims 11
- 230000003612 virological effect Effects 0.000 claims 10
- 230000035772 mutation Effects 0.000 claims 9
- 241000700605 Viruses Species 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 108020004414 DNA Proteins 0.000 claims 3
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 claims 3
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 claims 3
- 230000001419 dependent effect Effects 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 3
- 241001515965 unidentified phage Species 0.000 claims 3
- 102000004190 Enzymes Human genes 0.000 claims 2
- 108090000790 Enzymes Proteins 0.000 claims 2
- 208000004692 Pneumovirus Infections Diseases 0.000 claims 2
- 241000725643 Respiratory syncytial virus Species 0.000 claims 2
- 108010067390 Viral Proteins Proteins 0.000 claims 2
- 238000004113 cell culture Methods 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 101150039699 M2-1 gene Proteins 0.000 claims 1
- 108010052285 Membrane Proteins Proteins 0.000 claims 1
- 101710141454 Nucleoprotein Proteins 0.000 claims 1
- 108020005202 Viral DNA Proteins 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- 230000037430 deletion Effects 0.000 claims 1
- 238000012217 deletion Methods 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000011159 matrix material Substances 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL0300930 | 2003-12-24 | ||
| NLPCT/NL03/00930 | 2003-12-24 | ||
| PCT/NL2004/000911 WO2005061698A1 (en) | 2003-12-24 | 2004-12-24 | A respiratory syncytial virus with a genomic deficiency complemented in trans |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007516721A JP2007516721A (ja) | 2007-06-28 |
| JP2007516721A5 true JP2007516721A5 (https=) | 2008-01-17 |
| JP4814799B2 JP4814799B2 (ja) | 2011-11-16 |
Family
ID=34709376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006546873A Expired - Fee Related JP4814799B2 (ja) | 2003-12-24 | 2004-12-24 | トランスに相補されたゲノム欠損を有する呼吸器合胞体ウイルス |
Country Status (23)
| Country | Link |
|---|---|
| US (3) | US9107939B2 (https=) |
| EP (2) | EP2500419B1 (https=) |
| JP (1) | JP4814799B2 (https=) |
| KR (1) | KR101266715B1 (https=) |
| CN (1) | CN1922309B (https=) |
| AU (1) | AU2004303719B2 (https=) |
| BR (1) | BRPI0418093A (https=) |
| CA (1) | CA2551009C (https=) |
| CY (1) | CY1118741T1 (https=) |
| DK (1) | DK1699919T3 (https=) |
| EA (1) | EA011878B1 (https=) |
| ES (2) | ES2618523T3 (https=) |
| HU (1) | HUE032898T2 (https=) |
| IL (1) | IL176500A (https=) |
| LT (1) | LT1699919T (https=) |
| NO (1) | NO334756B1 (https=) |
| NZ (1) | NZ548107A (https=) |
| PL (1) | PL1699919T3 (https=) |
| PT (1) | PT1699919T (https=) |
| SI (1) | SI1699919T1 (https=) |
| TR (1) | TR201808496T4 (https=) |
| WO (1) | WO2005061698A1 (https=) |
| ZA (1) | ZA200605218B (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201121210D0 (en) * | 2011-12-09 | 2012-01-18 | Health Prot Agency | Respiratory infection assay |
| WO2013133702A1 (en) | 2012-03-05 | 2013-09-12 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Methods and compositions for stabilizing dried biological materials |
| CN113322264B (zh) | 2013-03-14 | 2024-05-31 | 爱默蕾大学 | 具有沉默突变的重组rsv、其相关疫苗和方法 |
| BR112015031541A2 (pt) | 2013-06-17 | 2017-07-25 | De Staat Der Nederlanden Vert Door De Mini Van Vws Miniie Van Volksgezondheid Welzijn En Sport | métodos para o impedimento da agregação de componentes virais |
| CN106659777A (zh) | 2014-06-13 | 2017-05-10 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合产品 |
| MX2018005462A (es) | 2015-10-29 | 2018-08-01 | Univ Emory | Composiciones inmunogénicas de rsv quimérico y métodos de uso. |
| US10626126B2 (en) * | 2016-04-08 | 2020-04-21 | Pulmocide Limited | Compounds |
| CN112746059A (zh) * | 2020-09-15 | 2021-05-04 | 清华大学 | 基于病毒结构蛋白遗传互补的冠状病毒细胞模型 |
| CN112501134B (zh) * | 2020-12-09 | 2023-01-20 | 贵州医科大学附属医院 | 一种人呼吸道合胞病毒毒株及其应用 |
| CN114990079B (zh) * | 2022-04-29 | 2023-07-04 | 广州医科大学附属第一医院（广州呼吸中心） | 治疗性缺陷干扰颗粒及其在制备用于防治rsv病毒感染的产品中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT702085E (pt) | 1994-07-18 | 2004-04-30 | Karl Klaus Conzelmann | Virus de arn de cadeia negativa nao segmentada infeccioso recombinante |
| US5789229A (en) | 1994-09-30 | 1998-08-04 | Uab Research Foundation | Stranded RNA virus particles |
| AU727923B2 (en) | 1995-09-27 | 2001-01-04 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Production of infectious respiratory syncytial virus from cloned nucleotide sequences |
| EP0912724B1 (en) | 1996-07-15 | 2009-12-09 | The Government of The United States of America, as represented by The Department of Health and Human Services | Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences |
| EP1035205A1 (en) | 1999-03-08 | 2000-09-13 | Stichting Dienst Landbouwkundig Onderzoek | Non-spreading pestivirus |
| AU2001263896A1 (en) | 2000-06-23 | 2002-01-14 | Akzo Nobel N.V. | Attenuated bovine respiratory syncytial virus |
| WO2003029416A2 (en) * | 2001-10-01 | 2003-04-10 | Uab Research Foundation | Recombinant respiratory syncytial viruses with deleted surface glycoprotein genes and uses thereof |
-
2004
- 2004-12-24 CN CN2004800420638A patent/CN1922309B/zh not_active Expired - Fee Related
- 2004-12-24 HU HUE04808827A patent/HUE032898T2/hu unknown
- 2004-12-24 NZ NZ548107A patent/NZ548107A/en not_active IP Right Cessation
- 2004-12-24 TR TR2018/08496T patent/TR201808496T4/tr unknown
- 2004-12-24 ES ES04808827.2T patent/ES2618523T3/es not_active Expired - Lifetime
- 2004-12-24 EP EP12172153.4A patent/EP2500419B1/en not_active Expired - Lifetime
- 2004-12-24 BR BRPI0418093-3A patent/BRPI0418093A/pt not_active Application Discontinuation
- 2004-12-24 JP JP2006546873A patent/JP4814799B2/ja not_active Expired - Fee Related
- 2004-12-24 LT LTEP04808827.2T patent/LT1699919T/lt unknown
- 2004-12-24 WO PCT/NL2004/000911 patent/WO2005061698A1/en not_active Ceased
- 2004-12-24 CA CA2551009A patent/CA2551009C/en not_active Expired - Fee Related
- 2004-12-24 PL PL04808827T patent/PL1699919T3/pl unknown
- 2004-12-24 US US10/583,800 patent/US9107939B2/en not_active Expired - Fee Related
- 2004-12-24 DK DK04808827.2T patent/DK1699919T3/en active
- 2004-12-24 PT PT48088272T patent/PT1699919T/pt unknown
- 2004-12-24 EP EP04808827.2A patent/EP1699919B1/en not_active Expired - Lifetime
- 2004-12-24 EA EA200601218A patent/EA011878B1/ru not_active IP Right Cessation
- 2004-12-24 SI SI200432377A patent/SI1699919T1/sl unknown
- 2004-12-24 AU AU2004303719A patent/AU2004303719B2/en not_active Ceased
- 2004-12-24 KR KR1020067014600A patent/KR101266715B1/ko not_active Expired - Fee Related
- 2004-12-24 ES ES12172153.4T patent/ES2670713T3/es not_active Expired - Lifetime
-
2006
- 2006-06-22 IL IL176500A patent/IL176500A/en active IP Right Grant
- 2006-06-23 ZA ZA200605218A patent/ZA200605218B/en unknown
- 2006-06-26 NO NO20062967A patent/NO334756B1/no not_active IP Right Cessation
-
2015
- 2015-07-31 US US14/815,131 patent/US9889168B2/en not_active Expired - Fee Related
-
2017
- 2017-02-28 CY CY20171100266T patent/CY1118741T1/el unknown
-
2018
- 2018-01-09 US US15/865,630 patent/US10967014B2/en not_active Expired - Fee Related
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