JP2007509116A - アンドロゲン受容体モジュレーター - Google Patents

アンドロゲン受容体モジュレーター Download PDF

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Publication number
JP2007509116A
JP2007509116A JP2006536167A JP2006536167A JP2007509116A JP 2007509116 A JP2007509116 A JP 2007509116A JP 2006536167 A JP2006536167 A JP 2006536167A JP 2006536167 A JP2006536167 A JP 2006536167A JP 2007509116 A JP2007509116 A JP 2007509116A
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Prior art keywords
methyl
nitro
trifluoromethyl
phenylamino
ylamino
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JP2007509116A5 (https=
Inventor
イェルンステッド，ヘンリク
ガルグ，ニーラジ
グスタフソン，アニーカ
ジルナー，ミカエル
コラゾ，アナ マリア ガルシア
コッホ，エバ
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Karo Healthcare AB
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Karo Pharma AB
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Publication of JP2007509116A publication Critical patent/JP2007509116A/ja
Publication of JP2007509116A5 publication Critical patent/JP2007509116A5/ja
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/04—Nitro compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61P13/08—Drugs for disorders of the urinary system of the prostate
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    • C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
    • C07C215/52—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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    • C07C215/60—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains further substituted by hydroxy groups with hydroxy groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain the chain having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
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JP2008515998A (ja) * 2004-10-13 2008-05-15 スミスクライン ビーチャム コーポレーション 化合物
JP2012509949A (ja) * 2008-11-24 2012-04-26 ビーエーエスエフ ソシエタス・ヨーロピア 熱潜在性塩基を含む硬化性組成物
US8969577B2 (en) 2008-11-24 2015-03-03 Basf Se Curable composition comprising a thermolatent base
JP2013515705A (ja) * 2009-12-23 2013-05-09 ガルデルマ・リサーチ・アンド・デヴェロップメント 新規なフェノール誘導体、及び医薬として又は化粧品としてのその使用

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