JP2007508301A5 - - Google Patents
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- Publication number
- JP2007508301A5 JP2007508301A5 JP2006533949A JP2006533949A JP2007508301A5 JP 2007508301 A5 JP2007508301 A5 JP 2007508301A5 JP 2006533949 A JP2006533949 A JP 2006533949A JP 2006533949 A JP2006533949 A JP 2006533949A JP 2007508301 A5 JP2007508301 A5 JP 2007508301A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- amino
- tetrahydro
- benzyl
- carboxylic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50973603P | 2003-10-08 | 2003-10-08 | |
| US60/509,736 | 2003-10-08 | ||
| PCT/US2004/030907 WO2005037796A1 (en) | 2003-10-08 | 2004-10-07 | Compounds and methods for treating dyslipidemia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007508301A JP2007508301A (ja) | 2007-04-05 |
| JP2007508301A5 true JP2007508301A5 (OSRAM) | 2011-05-19 |
| JP4773969B2 JP4773969B2 (ja) | 2011-09-14 |
Family
ID=34465112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006533949A Expired - Fee Related JP4773969B2 (ja) | 2003-10-08 | 2004-10-07 | 脂質代謝異常の治療ための化合物及び方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US7749992B2 (OSRAM) |
| EP (2) | EP1670768B1 (OSRAM) |
| JP (1) | JP4773969B2 (OSRAM) |
| KR (1) | KR20060085675A (OSRAM) |
| CN (1) | CN1863778A (OSRAM) |
| AT (1) | ATE442358T1 (OSRAM) |
| AU (1) | AU2004282101A1 (OSRAM) |
| BR (1) | BRPI0414186A (OSRAM) |
| CA (1) | CA2537942A1 (OSRAM) |
| CY (1) | CY1110537T1 (OSRAM) |
| DE (1) | DE602004023100D1 (OSRAM) |
| DK (1) | DK1670768T3 (OSRAM) |
| EA (1) | EA200600737A1 (OSRAM) |
| EC (1) | ECSP066484A (OSRAM) |
| ES (1) | ES2332051T3 (OSRAM) |
| HR (1) | HRP20090581T1 (OSRAM) |
| IL (1) | IL173819A0 (OSRAM) |
| MA (1) | MA28268A1 (OSRAM) |
| MX (1) | MXPA06003927A (OSRAM) |
| NO (1) | NO20062074L (OSRAM) |
| PL (1) | PL1670768T3 (OSRAM) |
| PT (1) | PT1670768E (OSRAM) |
| SI (1) | SI1670768T1 (OSRAM) |
| WO (1) | WO2005037796A1 (OSRAM) |
| ZA (1) | ZA200602888B (OSRAM) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE402180T1 (de) * | 2004-03-26 | 2008-08-15 | Lilly Co Eli | Verbindungen zur behandlung von dyslipidemie |
| BRPI0512523A (pt) | 2004-06-24 | 2008-03-11 | Lilly Co Eli | composto ou um sal, enanciÈmero, racemato, diastereÈmero ou mistura de diastereÈmeros farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de um composto |
| US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7790770B2 (en) * | 2005-11-23 | 2010-09-07 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| US7652023B2 (en) * | 2005-11-23 | 2010-01-26 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
| TWI450896B (zh) * | 2009-06-30 | 2014-09-01 | Lilly Co Eli | 反式－４－〔〔（５ｓ）－５－〔〔〔３，５－雙（三氟甲基）苯基〕甲基〕（２－甲基－２ｈ－四唑－５－基）胺基〕－２，３，４，５－四氫－７，９－二甲基－１ｈ－１－苯并氮呯－１－基〕甲基〕－環己基羧酸 |
| CN103833636B (zh) * | 2014-03-31 | 2015-09-02 | 武汉武药制药有限公司 | 一种莫扎伐普坦中间体的合成方法 |
| AU2016302755B2 (en) * | 2015-07-31 | 2020-09-10 | Arena Pharmaceuticals, Inc. | 5-HT2C receptor agonists and compositions and methods of use |
| EP3588064B1 (en) * | 2017-02-23 | 2022-09-07 | IHI Corporation | Oh radical detection probe, oh radical measurement device, and oh radical measurement method |
| CR20210207A (es) | 2018-10-24 | 2021-09-02 | Viiv Healthcare Uk No 5 Ltd | Inhibidores de la replicación del virus de la inmunodeficiencia humana |
| US20230149408A1 (en) | 2020-04-15 | 2023-05-18 | Viiv Healthcare Uk (No. 5) Limited | Inhibitors of human immunodeficiency virus replication |
| CN113636977B (zh) * | 2021-09-01 | 2022-12-20 | 温州大学 | 2-芳基苯并氮杂卓及其衍生物的合成方法 |
| CN117088814A (zh) * | 2023-02-16 | 2023-11-21 | 烟台大学 | 一种三氟甲硫化氮杂-8/9元环化合物的制备方法 |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2905909B2 (ja) * | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
| TW270927B (OSRAM) | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| US5484783A (en) | 1994-03-24 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives |
| WO1995025532A1 (en) | 1994-03-24 | 1995-09-28 | Merrell Pharmaceuticals Inc. | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic aminoacetylmercapto derivatives |
| DE69535486T2 (de) | 1994-06-15 | 2008-04-10 | Otsuka Pharmaceutical Co., Ltd. | Benzoheterocyclische Verbindungen verwendbar als Vasopressin- oder Oxytocin-Modulatoren |
| GB9523526D0 (en) | 1995-11-17 | 1996-01-17 | Zeneca Ltd | Therapeutic compounds |
| JPH09214746A (ja) | 1996-02-02 | 1997-08-15 | Ricoh Co Ltd | 画像出力システム及び画像形成装置 |
| DE19627431A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Heterocyclisch kondensierte Pyridine |
| HRP970330B1 (en) | 1996-07-08 | 2004-06-30 | Bayer Ag | Cycloalkano pyridines |
| US6207671B1 (en) | 1996-07-08 | 2001-03-27 | Bayer Aktiengesellschaft | Cycloalkano-pyridines |
| DE19627430A1 (de) | 1996-07-08 | 1998-01-15 | Bayer Ag | Bicyclisch kondensierte Pyridine |
| US6333349B1 (en) | 1997-02-26 | 2001-12-25 | Aventis Pharma Deutschland Gmbh | Sulfonamide-substituted fused 7-membered ring compounds, their use as a medicament, and pharmaceutical preparations comprising them |
| DE19709125A1 (de) | 1997-03-06 | 1998-09-10 | Bayer Ag | Substituierte Chinoline |
| JPH10287662A (ja) | 1997-04-08 | 1998-10-27 | Kitasato Inst:The | Ｆｏ−５６３７ａ物質及びｂ物質並びにそれらの製造法 |
| JP2959765B2 (ja) | 1997-12-12 | 1999-10-06 | 日本たばこ産業株式会社 | ３−ピペリジル−４−オキソキナゾリン誘導体及びそれを含有してなる医薬組成物 |
| US6197786B1 (en) | 1998-09-17 | 2001-03-06 | Pfizer Inc | 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines |
| US6147090A (en) | 1998-09-17 | 2000-11-14 | Pfizer Inc. | 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| US6147089A (en) | 1998-09-17 | 2000-11-14 | Pfizer Inc. | Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines |
| GT199900147A (es) | 1998-09-17 | 1999-09-06 | 1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas. | |
| HN2000000203A (es) | 1999-11-30 | 2001-06-13 | Pfizer Prod Inc | Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas. |
| CO5271716A1 (es) | 1999-11-30 | 2003-04-30 | Pfizer Prod Inc | Cristales de 4- carboxamino 1,2,3,4-tetrahidroquinolina 2- sustituida |
| US6664522B2 (en) * | 2000-03-30 | 2003-12-16 | Homer L. Spencer | Method and apparatus for sealing multiple casings for oil and gas wells |
| US7115279B2 (en) | 2000-08-03 | 2006-10-03 | Curatolo William J | Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors |
| CA2445693A1 (en) | 2001-04-30 | 2002-11-07 | Pfizer Products Inc. | Compounds useful as intermediates for 4-aminoquinoline derivatives |
| PL368850A1 (en) | 2001-06-21 | 2005-04-04 | Pfizer Products Inc. | Self-emulsifying formulations of cholesteryl ester transfer protein inhibitors |
| DE10148436A1 (de) | 2001-10-01 | 2003-04-17 | Bayer Ag | Tetrahydrochinoline |
| JP2005522424A (ja) * | 2002-02-01 | 2005-07-28 | ファイザー・プロダクツ・インク | コレステリルエステル転移タンパク質インヒビターの制御放出性薬剤投与形態 |
| DE60335545D1 (de) | 2002-07-01 | 2011-02-10 | Cytec Surface Specialties Sa | Wasserverdünnbare polymervorläufer sowie herstellung und verwendung davon |
| US7332514B2 (en) | 2002-08-30 | 2008-02-19 | Japan Tobacco Inc. | Dibenzylamine compound and medicinal use thereof |
| KR20050055747A (ko) | 2002-10-04 | 2005-06-13 | 밀레니엄 파머슈티컬스 인코퍼레이티드 | 염증 질환 치료용의 ｐｇｄ2 수용체 길항제 |
| WO2004078730A2 (en) | 2003-03-04 | 2004-09-16 | Takasago International Corporation | Method for producing optically active amines |
| US20040204450A1 (en) | 2003-03-28 | 2004-10-14 | Pfizer Inc | Quinoline and quinoxaline compounds |
| EP1670765A2 (en) | 2003-09-30 | 2006-06-21 | Pfizer Products Inc. | Cetp inhibitors and metabolites thereof |
| ATE402180T1 (de) | 2004-03-26 | 2008-08-15 | Lilly Co Eli | Verbindungen zur behandlung von dyslipidemie |
| BRPI0512523A (pt) | 2004-06-24 | 2008-03-11 | Lilly Co Eli | composto ou um sal, enanciÈmero, racemato, diastereÈmero ou mistura de diastereÈmeros farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso de um composto |
-
2004
- 2004-10-07 AU AU2004282101A patent/AU2004282101A1/en not_active Abandoned
- 2004-10-07 PL PL04793889T patent/PL1670768T3/pl unknown
- 2004-10-07 CN CNA2004800295407A patent/CN1863778A/zh active Pending
- 2004-10-07 PT PT04793889T patent/PT1670768E/pt unknown
- 2004-10-07 DE DE602004023100T patent/DE602004023100D1/de not_active Expired - Lifetime
- 2004-10-07 KR KR1020067006837A patent/KR20060085675A/ko not_active Ceased
- 2004-10-07 EP EP04793889A patent/EP1670768B1/en not_active Expired - Lifetime
- 2004-10-07 JP JP2006533949A patent/JP4773969B2/ja not_active Expired - Fee Related
- 2004-10-07 DK DK04793889T patent/DK1670768T3/da active
- 2004-10-07 SI SI200431294T patent/SI1670768T1/sl unknown
- 2004-10-07 US US10/574,649 patent/US7749992B2/en not_active Expired - Fee Related
- 2004-10-07 CA CA002537942A patent/CA2537942A1/en not_active Abandoned
- 2004-10-07 HR HR20090581T patent/HRP20090581T1/hr unknown
- 2004-10-07 WO PCT/US2004/030907 patent/WO2005037796A1/en not_active Ceased
- 2004-10-07 BR BRPI0414186-5A patent/BRPI0414186A/pt not_active Application Discontinuation
- 2004-10-07 EA EA200600737A patent/EA200600737A1/ru unknown
- 2004-10-07 ES ES04793889T patent/ES2332051T3/es not_active Expired - Lifetime
- 2004-10-07 AT AT04793889T patent/ATE442358T1/de active
- 2004-10-07 EP EP09157118A patent/EP2098512A1/en not_active Withdrawn
- 2004-10-07 MX MXPA06003927A patent/MXPA06003927A/es not_active Application Discontinuation
-
2006
- 2006-02-20 IL IL173819A patent/IL173819A0/en unknown
- 2006-04-05 EC EC2006006484A patent/ECSP066484A/es unknown
- 2006-04-07 ZA ZA200602888A patent/ZA200602888B/en unknown
- 2006-05-03 MA MA28999A patent/MA28268A1/fr unknown
- 2006-05-08 NO NO20062074A patent/NO20062074L/no not_active Application Discontinuation
-
2009
- 2009-11-05 CY CY20091101151T patent/CY1110537T1/el unknown
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