JP2007137890A5 - - Google Patents
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- Publication number
- JP2007137890A5 JP2007137890A5 JP2007020702A JP2007020702A JP2007137890A5 JP 2007137890 A5 JP2007137890 A5 JP 2007137890A5 JP 2007020702 A JP2007020702 A JP 2007020702A JP 2007020702 A JP2007020702 A JP 2007020702A JP 2007137890 A5 JP2007137890 A5 JP 2007137890A5
- Authority
- JP
- Japan
- Prior art keywords
- solution
- alcohol
- hydrochloride
- algravin
- aminoalgravin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KZ960995 | 1996-12-20 | ||
| KZ960995.1 | 1996-12-20 | ||
| KZ970397.1 | 1997-04-23 | ||
| KZ970397 | 1997-04-26 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51603098A Division JP2001505548A (ja) | 1996-12-20 | 1997-12-19 | 凍結乾燥ハイドロクロライド−１β，１０β−エポキシ−１３−ジメチルアミノ−グアヤ−３（４）−エン−６，１２−オリドの生成方法および装置 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2007137890A JP2007137890A (ja) | 2007-06-07 |
| JP2007137890A5 true JP2007137890A5 (enExample) | 2007-09-13 |
| JP2007137890A6 JP2007137890A6 (ja) | 2007-11-08 |
Family
ID=26639596
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51603098A Ceased JP2001505548A (ja) | 1996-12-20 | 1997-12-19 | 凍結乾燥ハイドロクロライド−１β，１０β−エポキシ−１３−ジメチルアミノ−グアヤ−３（４）−エン−６，１２−オリドの生成方法および装置 |
| JP2007020702A Pending JP2007137890A (ja) | 1996-12-20 | 2007-01-31 | 凍結乾燥ハイドロクロライド−１β，１０β−エポキシ−１３−ジメチルアミノ−グアヤ−３（４）−エン−６，１２−オリドの生成方法および装置 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP51603098A Ceased JP2001505548A (ja) | 1996-12-20 | 1997-12-19 | 凍結乾燥ハイドロクロライド−１β，１０β−エポキシ−１３−ジメチルアミノ−グアヤ−３（４）−エン−６，１２−オリドの生成方法および装置 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0946565B1 (enExample) |
| JP (2) | JP2001505548A (enExample) |
| CN (1) | CN1095845C (enExample) |
| AT (1) | ATE252104T1 (enExample) |
| DE (1) | DE69725604T2 (enExample) |
| WO (1) | WO1998028303A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5994388A (en) | 1997-03-18 | 1999-11-30 | The Children's Medical Center Corporation | Cytochalasin and isoindolinone derivatives as inhibitors of angiogenesis |
| AU2001231763A1 (en) | 2000-02-24 | 2001-09-03 | Janssen Pharmaceutica N.V. | Dosing regimen |
| EP1491245B1 (en) * | 2002-03-20 | 2008-08-06 | Matsushita Electric Industrial Co., Ltd. | Extractor |
| DE10326152A1 (de) * | 2003-06-06 | 2005-01-05 | Aventis Pharma Deutschland Gmbh | Verfahren und Vorrichtung zur quantitativen Analyse von Lösungen und Dispersionen mittels Nahinfrarot-Spektroskopie |
| US20050003422A1 (en) | 2003-07-01 | 2005-01-06 | Mitch Reponi | Methods for assessing and treating cancer |
| DE102004037002B4 (de) * | 2004-07-30 | 2006-06-14 | Chemieanlagenbau Chemnitz Gmbh | Verfahren zur Herstellung von Dimethylaminoarglabin-Hydrochlorid |
| HRP20130399T1 (hr) | 2004-11-05 | 2013-06-30 | Janssen Pharmaceutica Nv | Terapeutska upotreba inhibitora farenziltransferaze i postupci praä†enja njihove efikasnosti |
| US20060281788A1 (en) | 2005-06-10 | 2006-12-14 | Baumann Christian A | Synergistic modulation of flt3 kinase using a flt3 inhibitor and a farnesyl transferase inhibitor |
| US8697716B2 (en) | 2006-04-20 | 2014-04-15 | Janssen Pharmaceutica Nv | Method of inhibiting C-KIT kinase |
| WO2007124316A1 (en) | 2006-04-20 | 2007-11-01 | Janssen Pharmaceutica N.V. | Heterocyclic compounds as inhibitors of c-fms kinase |
| MX2008013531A (es) | 2006-04-20 | 2009-01-20 | Janssen Pharmaceutica Nv | Inhibidores de c-fms cinasa. |
| CN101511843B (zh) * | 2006-09-19 | 2012-12-26 | 谢尔加济明扎萨洛维奇·阿德科诺夫 | 制备盐酸1(10)β-环氧-13-二甲基氨基-5,7α,6,11β(H)-愈创木-3(4)-烯-6,12-内酯,一种冻干的抗肿瘤制品"阿格拉滨"的方法 |
| JO3240B1 (ar) | 2007-10-17 | 2018-03-08 | Janssen Pharmaceutica Nv | c-fms مثبطات كيناز |
| CN102190663B (zh) * | 2010-03-02 | 2013-11-13 | 石药集团中奇制药技术（石家庄）有限公司 | 一种二甲氨基阿格拉宾盐酸盐晶型 |
| CN102190662B (zh) * | 2010-03-02 | 2014-06-25 | 石药集团中奇制药技术（石家庄）有限公司 | 一种二甲氨基阿格拉宾盐酸盐的制备方法 |
| CN102372723B (zh) * | 2010-08-19 | 2014-03-26 | 石药集团中奇制药技术（石家庄）有限公司 | 一种从多花蒿中提取阿格拉宾的方法 |
| EP2882757B1 (en) | 2012-08-07 | 2016-10-05 | Janssen Pharmaceutica, N.V. | Process for the preparation of heterocyclic ester derivatives |
| CN104520295B (zh) | 2012-08-07 | 2017-07-18 | 詹森药业有限公司 | 用于制备c‑fms激酶抑制剂的方法 |
| CN102850372A (zh) * | 2012-10-15 | 2013-01-02 | 河北医科大学 | 一种蓍草倍半萜内酯化合物及其提取方法和应用 |
| CN103833766B (zh) * | 2012-11-23 | 2016-12-21 | 天津尚德药缘科技股份有限公司 | 阿格拉滨二甲胺富马酸盐及其在药物制备中的用途 |
| JP6630742B2 (ja) | 2015-08-17 | 2020-01-15 | クラ オンコロジー， インコーポレイテッド | ファルネシルトランスフェラーゼ阻害剤を用いて癌患者を治療する方法 |
| CN105251236B (zh) * | 2015-11-02 | 2018-01-16 | 济宁金百特生物机械有限公司 | 逆流提取装置 |
| WO2017184968A1 (en) | 2016-04-22 | 2017-10-26 | Kura Oncology, Inc. | Methods of selecting cancer patients for treatment with farnesyltransferase inhibitors |
| EP3534885B1 (en) | 2016-11-03 | 2021-01-20 | Kura Oncology, Inc. | Farnesyltransferase inhibitors for use in treating cancer |
| KR20200090982A (ko) | 2017-02-21 | 2020-07-29 | 쿠라 온콜로지, 인크. | 파르네실트랜스퍼라제 억제제를 사용하는 암 환자의 치료 방법 |
| US10137121B2 (en) | 2017-02-21 | 2018-11-27 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| MX2020001207A (es) | 2017-08-07 | 2020-03-20 | Kura Oncology Inc | Metodos de tratamiento del cancer con inhibidores de farnesiltransferasa. |
| US10806730B2 (en) | 2017-08-07 | 2020-10-20 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| WO2019113269A1 (en) | 2017-12-08 | 2019-06-13 | Kura Oncology, Inc. | Methods of treating cancer patients with farnesyltransferase inhibitors |
| CA3117968A1 (en) | 2018-11-01 | 2020-05-07 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| CA3124616A1 (en) | 2018-12-21 | 2020-06-25 | Kura Oncology, Inc. | Therapies for squamous cell carcinomas |
| US20220142983A1 (en) | 2019-03-01 | 2022-05-12 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| US20220143006A1 (en) | 2019-03-15 | 2022-05-12 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| JP7641232B2 (ja) | 2019-03-29 | 2025-03-06 | クラ オンコロジー， インコーポレイテッド | ファルネシルトランスフェラーゼ阻害剤による扁平上皮癌の治療方法 |
| WO2020205387A1 (en) | 2019-04-01 | 2020-10-08 | Kura Oncology, Inc. | Methods of treating cancer with farnesyltransferase inhibitors |
| WO2020223583A1 (en) | 2019-05-02 | 2020-11-05 | Kura Oncology, Inc. | Methods of treating acute myeloid leukemia with farnesyltransferase inhibitors |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1627208A1 (ru) * | 1988-05-24 | 1991-02-15 | Всесоюзный научно-исследовательский институт консервной и овощесушильной промышленности | Секционный лопастной экстрактор дл сухого растительного сырь |
-
1997
- 1997-12-19 JP JP51603098A patent/JP2001505548A/ja not_active Ceased
- 1997-12-19 DE DE69725604T patent/DE69725604T2/de not_active Expired - Lifetime
- 1997-12-19 WO PCT/KZ1997/000006 patent/WO1998028303A1/en not_active Ceased
- 1997-12-19 CN CN97181524A patent/CN1095845C/zh not_active Expired - Lifetime
- 1997-12-19 EP EP97947981A patent/EP0946565B1/en not_active Expired - Lifetime
- 1997-12-19 AT AT97947981T patent/ATE252104T1/de not_active IP Right Cessation
-
2007
- 2007-01-31 JP JP2007020702A patent/JP2007137890A/ja active Pending
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