JP2006525288A5 - - Google Patents
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- JP2006525288A5 JP2006525288A5 JP2006505607A JP2006505607A JP2006525288A5 JP 2006525288 A5 JP2006525288 A5 JP 2006525288A5 JP 2006505607 A JP2006505607 A JP 2006505607A JP 2006505607 A JP2006505607 A JP 2006505607A JP 2006525288 A5 JP2006525288 A5 JP 2006525288A5
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- JP
- Japan
- Prior art keywords
- sequence
- type
- amino acid
- information
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- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES200301054A ES2246105B1 (es) | 2003-05-08 | 2003-05-08 | Uso de anticuerpos para el tratamiento de enfermedades amiloideas. |
| PCT/ES2004/000194 WO2004098631A1 (es) | 2003-05-08 | 2004-05-03 | Método de tratamiento de la enfermedad de alzheimer |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011191515A Division JP2012006967A (ja) | 2003-05-08 | 2011-09-02 | アルツハイマー病治療方法 |
| JP2014038360A Division JP2014129389A (ja) | 2003-05-08 | 2014-02-28 | アルツハイマー病治療方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006525288A JP2006525288A (ja) | 2006-11-09 |
| JP2006525288A5 true JP2006525288A5 (enExample) | 2007-02-08 |
Family
ID=32982086
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006505607A Pending JP2006525288A (ja) | 2003-05-08 | 2004-05-03 | アルツハイマー病治療方法 |
| JP2011191515A Pending JP2012006967A (ja) | 2003-05-08 | 2011-09-02 | アルツハイマー病治療方法 |
| JP2014038360A Withdrawn JP2014129389A (ja) | 2003-05-08 | 2014-02-28 | アルツハイマー病治療方法 |
| JP2016003772A Withdrawn JP2016065100A (ja) | 2003-05-08 | 2016-01-12 | アルツハイマー病治療方法 |
| JP2018088643A Pending JP2018119011A (ja) | 2003-05-08 | 2018-05-02 | アルツハイマー病治療方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011191515A Pending JP2012006967A (ja) | 2003-05-08 | 2011-09-02 | アルツハイマー病治療方法 |
| JP2014038360A Withdrawn JP2014129389A (ja) | 2003-05-08 | 2014-02-28 | アルツハイマー病治療方法 |
| JP2016003772A Withdrawn JP2016065100A (ja) | 2003-05-08 | 2016-01-12 | アルツハイマー病治療方法 |
| JP2018088643A Pending JP2018119011A (ja) | 2003-05-08 | 2018-05-02 | アルツハイマー病治療方法 |
Country Status (19)
| Country | Link |
|---|---|
| US (6) | US20090162362A1 (enExample) |
| EP (5) | EP2082747A3 (enExample) |
| JP (5) | JP2006525288A (enExample) |
| CN (2) | CN101264326A (enExample) |
| AT (1) | ATE435024T1 (enExample) |
| AU (2) | AU2004237373A1 (enExample) |
| BR (1) | BRPI0410684A (enExample) |
| CA (1) | CA2524571C (enExample) |
| CY (1) | CY1109454T1 (enExample) |
| DE (1) | DE602004021797D1 (enExample) |
| DK (3) | DK2075007T3 (enExample) |
| ES (6) | ES2246177B1 (enExample) |
| IL (8) | IL171651A (enExample) |
| MX (1) | MXPA05010914A (enExample) |
| PL (3) | PL2075007T3 (enExample) |
| PT (3) | PT2075007E (enExample) |
| RU (2) | RU2385161C2 (enExample) |
| SI (1) | SI1623719T1 (enExample) |
| WO (1) | WO2004098631A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| US7732162B2 (en) | 2003-05-05 | 2010-06-08 | Probiodrug Ag | Inhibitors of glutaminyl cyclase for treating neurodegenerative diseases |
| ES2246177B1 (es) * | 2003-05-08 | 2007-03-01 | Universidad De Zaragoza. | Uso de anticuerpos para el tratamiento de enfermedades amiloideas. |
| AU2005290250A1 (en) | 2004-07-30 | 2006-04-06 | Rinat Neuroscience Corp. | Antibodies directed against amyloid-beta peptide and methods using same |
| PE20061323A1 (es) | 2005-04-29 | 2007-02-09 | Rinat Neuroscience Corp | Anticuerpos dirigidos contra el peptido amiloide beta y metodos que utilizan los mismos |
| PL1976877T5 (pl) | 2005-11-30 | 2017-09-29 | Abbvie Inc | Przeciwciała monoklonalne przeciwko białku amyloidu beta oraz ich zastosowania |
| RU2442793C2 (ru) | 2005-11-30 | 2012-02-20 | Эбботт Лэборетриз | АНТИТЕЛА ПРОТИВ ГЛОБУЛОМЕРА Аβ, ИХ АНТИГЕНСВЯЗЫВАЮЩИЕ ЧАСТИ, СООТВЕТСТВУЮЩИЕ ГИБРИДОМЫ, НУКЛЕИНОВЫЕ КИСЛОТЫ, ВЕКТОРЫ, КЛЕТКИ-ХОЗЯЕВА, СПОСОБЫ ПОЛУЧЕНИЯ УКАЗАННЫХ АНТИТЕЛ, КОМПОЗИЦИИ, СОДЕРЖАЩИЕ УКАЗАННЫЕ АНТИТЕЛА, ПРИМЕНЕНИЯ УКАЗАННЫХ АНТИТЕЛ И СПОСОБЫ ИСПОЛЬЗОВАНИЯ УКАЗАННЫХ АНТИТЕЛ |
| NZ568012A (en) * | 2005-12-12 | 2012-07-27 | Ac Immune Sa | A beta 1-42 specific monoclonal antibodies with therapeutic properties |
| RU2498999C2 (ru) * | 2006-07-14 | 2013-11-20 | Ац Иммуне Са | Гуманизированное антитело к амилоиду бета |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| US8895004B2 (en) | 2007-02-27 | 2014-11-25 | AbbVie Deutschland GmbH & Co. KG | Method for the treatment of amyloidoses |
| JP5930573B2 (ja) | 2007-03-01 | 2016-06-15 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤の新規使用 |
| WO2008128985A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thiourea derivatives as glutaminyl cyclase inhibitors |
| US8613923B2 (en) | 2007-06-12 | 2013-12-24 | Ac Immune S.A. | Monoclonal antibody |
| US8048420B2 (en) * | 2007-06-12 | 2011-11-01 | Ac Immune S.A. | Monoclonal antibody |
| AU2008311366B2 (en) * | 2007-10-05 | 2015-03-12 | Ac Immune S.A. | Use of anti-amyloid beta antibody in ocular diseases |
| PL2238166T3 (pl) * | 2007-10-05 | 2014-07-31 | Genentech Inc | Zastosowanie przeciwciała anty-Beta amyloidowego w chorobach oczu |
| EP2149380A1 (en) * | 2008-07-29 | 2010-02-03 | Medivet Pharma, S.L. | Veterinary immunotherapy compositions for the Aged Related Cognitive Dysfunction. |
| EP2258398A1 (en) * | 2009-05-26 | 2010-12-08 | Araclón Biotech, S. L. | Albumin-amyloid peptide conjugates and uses thereof |
| PL2475428T3 (pl) | 2009-09-11 | 2015-12-31 | Probiodrug Ag | Pochodne heterocykliczne jako inhibitory cyklazy glutaminowej |
| EP2510359B1 (en) | 2009-12-11 | 2015-09-02 | Araclón Biotech, S. L. | Methods and reagents for improved detection of amyloid beta peptides |
| ES2586231T3 (es) | 2010-03-03 | 2016-10-13 | Probiodrug Ag | Inhibidores de glutaminil ciclasa |
| MX2012010470A (es) | 2010-03-10 | 2012-10-09 | Probiodrug Ag | Inhibidores heterociclicos d ciclasa de glutaminilo (qc, ec .3 2. 5). |
| WO2011130377A2 (en) | 2010-04-15 | 2011-10-20 | Abbott Laboratories | Amyloid-beta binding proteins |
| US8541596B2 (en) | 2010-04-21 | 2013-09-24 | Probiodrug Ag | Inhibitors |
| US20130115227A1 (en) * | 2010-07-14 | 2013-05-09 | Renee C. Gaspar | Anti-addl monoclonal antibody and uses thereof |
| US9221900B2 (en) * | 2010-07-30 | 2015-12-29 | Ac Immune S.A. | Methods for identifying safe and functional humanized antibodies |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| EP2686313B1 (en) | 2011-03-16 | 2016-02-03 | Probiodrug AG | Benzimidazole derivatives as inhibitors of glutaminyl cyclase |
| EP3027205A4 (en) | 2013-07-28 | 2017-07-19 | Qantu Therapeutics, Inc. | Vaccine formulations that induce a th2 immune response |
| ES2571055B1 (es) * | 2016-02-15 | 2016-12-28 | Araclon Biotech, S.L. | Conjugado amiloide y usos y procedimientos del mismo |
| CN111201030B (zh) | 2017-07-25 | 2024-11-01 | 真和制药有限公司 | 通过阻断tim-3和其配体的相互作用治疗癌症 |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
| PL237739B1 (pl) | 2018-06-06 | 2021-05-17 | Univ Gdanski | Genisteina do zastosowania do leczenia choroby Alzheimera |
| KR20210124308A (ko) | 2019-01-30 | 2021-10-14 | 트루바인딩 아이엔씨. | 항-gal3 항체 및 이의 용도 |
| MX2022014786A (es) | 2020-05-26 | 2023-01-16 | Truebinding Inc | Metodos para tratar enfermedades inflamatorias mediante el bloqueo de galectina-3. |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339014C (en) * | 1987-10-08 | 1997-03-25 | Ronald E. Majocha | Antibodies to a4 amyloid peptide |
| WO1990012870A1 (en) * | 1989-04-14 | 1990-11-01 | Research Foundation For Mental Hygiene, Inc. | Monoclonal antibody to amyloid peptide |
| JP2980677B2 (ja) | 1990-04-27 | 1999-11-22 | マクマイケル,ジョン | 不正常なアミロイドβタンパク質と関連する中枢神経系疾患状態の治療のための方法および組成物 |
| EP0683234B2 (en) * | 1993-01-25 | 2007-06-06 | Takeda Chemical Industries, Ltd. | Antibody against beta-amyloid or their derivative and use thereof |
| US7427392B1 (en) * | 1994-11-14 | 2008-09-23 | Elan Pharmaceuticals, Inc. | Methods for aiding in the diagnosis of alzheimer's disease by measuring amyloid-β peptide (x-≧41) and tau |
| US8173127B2 (en) * | 1997-04-09 | 2012-05-08 | Intellect Neurosciences, Inc. | Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof |
| TWI239847B (en) * | 1997-12-02 | 2005-09-21 | Elan Pharm Inc | N-terminal fragment of Abeta peptide and an adjuvant for preventing and treating amyloidogenic disease |
| US6905686B1 (en) * | 1997-12-02 | 2005-06-14 | Neuralab Limited | Active immunization for treatment of alzheimer's disease |
| US7964192B1 (en) * | 1997-12-02 | 2011-06-21 | Janssen Alzheimer Immunotherapy | Prevention and treatment of amyloidgenic disease |
| EP1105163A4 (en) * | 1998-08-20 | 2003-05-02 | Univ California | METHOD FOR MARKING AMYLOID PLAQUES AND NEUROFIBRILLIC GIFTS |
| UA81216C2 (en) * | 1999-06-01 | 2007-12-25 | Prevention and treatment of amyloid disease | |
| EP1975179A1 (en) * | 2001-12-26 | 2008-10-01 | Araclon Biotech, S.L. | Polyclonal antibodies, preparation method thereof and use of same |
| EP1371986A1 (en) * | 2002-06-06 | 2003-12-17 | ABETA GmbH | Diagnosis of Alzheimer's disease based on the hAbeta42:hAbeta40 ratio |
| WO2004013172A2 (en) * | 2002-07-24 | 2004-02-12 | Innogenetics N.V. | Fragments of beta-amyloid as targets for vaccination against alzheimer disease |
| ES2201929B1 (es) * | 2002-09-12 | 2005-05-16 | Araclon Biotech, S.L. | Anticuerpos policlonales, metodo de preparacion y uso de los mismos. |
| AU2003279216A1 (en) * | 2002-10-09 | 2004-05-04 | Rinat Neuroscience Corp. | Methods of treating alzheimer's disease using antibodies directed against amyloid beta peptide and compositions thereof |
| KR20050118669A (ko) * | 2003-02-01 | 2005-12-19 | 뉴랄랩 리미티드 | 가용성 a-베타에 대한 항체를 생성하기 위한 능동 면역화 |
| ES2246177B1 (es) * | 2003-05-08 | 2007-03-01 | Universidad De Zaragoza. | Uso de anticuerpos para el tratamiento de enfermedades amiloideas. |
-
2003
- 2003-05-08 ES ES200403158A patent/ES2246177B1/es not_active Expired - Fee Related
- 2003-05-08 ES ES200301054A patent/ES2246105B1/es not_active Expired - Fee Related
- 2003-05-08 ES ES200403159A patent/ES2246178B1/es not_active Expired - Fee Related
-
2004
- 2004-05-03 PT PT81702227T patent/PT2075007E/pt unknown
- 2004-05-03 EP EP08170207A patent/EP2082747A3/en not_active Withdrawn
- 2004-05-03 US US10/555,865 patent/US20090162362A1/en not_active Abandoned
- 2004-05-03 EP EP04730882A patent/EP1623719B1/en not_active Expired - Lifetime
- 2004-05-03 PL PL08170222T patent/PL2075007T3/pl unknown
- 2004-05-03 DK DK08170222.7T patent/DK2075007T3/da active
- 2004-05-03 MX MXPA05010914A patent/MXPA05010914A/es active IP Right Grant
- 2004-05-03 PT PT100123421T patent/PT2356996E/pt unknown
- 2004-05-03 PL PL04730882T patent/PL1623719T3/pl unknown
- 2004-05-03 AT AT04730882T patent/ATE435024T1/de active
- 2004-05-03 EP EP08170222.7A patent/EP2075007B9/en not_active Expired - Lifetime
- 2004-05-03 BR BRPI0410684-9A patent/BRPI0410684A/pt not_active Application Discontinuation
- 2004-05-03 SI SI200431235T patent/SI1623719T1/sl unknown
- 2004-05-03 JP JP2006505607A patent/JP2006525288A/ja active Pending
- 2004-05-03 ES ES04730882T patent/ES2329369T3/es not_active Expired - Lifetime
- 2004-05-03 DE DE602004021797T patent/DE602004021797D1/de not_active Expired - Lifetime
- 2004-05-03 DK DK10012342.1T patent/DK2356996T5/da active
- 2004-05-03 AU AU2004237373A patent/AU2004237373A1/en not_active Abandoned
- 2004-05-03 PT PT04730882T patent/PT1623719E/pt unknown
- 2004-05-03 CA CA2524571A patent/CA2524571C/en not_active Expired - Fee Related
- 2004-05-03 EP EP10012340A patent/EP2305286A3/en not_active Withdrawn
- 2004-05-03 CN CNA2008100898940A patent/CN101264326A/zh active Pending
- 2004-05-03 CN CNA2004800125340A patent/CN1784240A/zh active Pending
- 2004-05-03 DK DK04730882T patent/DK1623719T3/da active
- 2004-05-03 RU RU2005134351/15A patent/RU2385161C2/ru active
- 2004-05-03 ES ES08170222T patent/ES2423281T3/es not_active Expired - Lifetime
- 2004-05-03 PL PL10012342T patent/PL2356996T3/pl unknown
- 2004-05-03 ES ES10012342T patent/ES2423590T3/es not_active Expired - Lifetime
- 2004-05-03 EP EP10012342.1A patent/EP2356996B9/en not_active Expired - Lifetime
- 2004-05-03 WO PCT/ES2004/000194 patent/WO2004098631A1/es not_active Ceased
-
2005
- 2005-10-27 IL IL171651A patent/IL171651A/en active IP Right Grant
-
2009
- 2009-10-02 CY CY20091101026T patent/CY1109454T1/el unknown
- 2009-12-25 RU RU2009148539/15A patent/RU2526155C2/ru active
-
2010
- 2010-08-30 IL IL207878A patent/IL207878A/en active IP Right Grant
- 2010-08-30 IL IL207875A patent/IL207875A/en active IP Right Grant
- 2010-08-30 IL IL207881A patent/IL207881A/en not_active IP Right Cessation
- 2010-08-30 IL IL207880A patent/IL207880A/en not_active IP Right Cessation
- 2010-08-30 IL IL207877A patent/IL207877A/en not_active IP Right Cessation
- 2010-08-30 IL IL207879A patent/IL207879A/en active IP Right Grant
- 2010-08-30 IL IL207876A patent/IL207876A/en not_active IP Right Cessation
-
2011
- 2011-01-17 AU AU2011200170A patent/AU2011200170C1/en not_active Ceased
- 2011-03-17 US US13/050,654 patent/US20110262458A1/en not_active Abandoned
- 2011-09-02 JP JP2011191515A patent/JP2012006967A/ja active Pending
-
2013
- 2013-09-13 US US14/026,374 patent/US20140044725A1/en not_active Abandoned
-
2014
- 2014-02-28 JP JP2014038360A patent/JP2014129389A/ja not_active Withdrawn
-
2016
- 2016-01-12 JP JP2016003772A patent/JP2016065100A/ja not_active Withdrawn
-
2017
- 2017-05-23 US US15/602,779 patent/US20170260234A1/en not_active Abandoned
-
2018
- 2018-05-02 JP JP2018088643A patent/JP2018119011A/ja active Pending
-
2020
- 2020-01-16 US US16/745,067 patent/US20200140488A1/en not_active Abandoned
-
2021
- 2021-03-26 US US17/213,720 patent/US20210214394A1/en not_active Abandoned
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