CY1109454T1 - Θεραπεια για τη νοσο του αλτσχαϊμερ και της αγγειακης εγκεφαλικης αμυλοειδοπαθειας - Google Patents

Θεραπεια για τη νοσο του αλτσχαϊμερ και της αγγειακης εγκεφαλικης αμυλοειδοπαθειας

Info

Publication number
CY1109454T1
CY1109454T1 CY20091101026T CY091101026T CY1109454T1 CY 1109454 T1 CY1109454 T1 CY 1109454T1 CY 20091101026 T CY20091101026 T CY 20091101026T CY 091101026 T CY091101026 T CY 091101026T CY 1109454 T1 CY1109454 T1 CY 1109454T1
Authority
CY
Cyprus
Prior art keywords
disease
alzheimer
treatment
amyloidopathy
vascular cerebral
Prior art date
Application number
CY20091101026T
Other languages
English (en)
Inventor
Barrio Manuel Sarasa
Original Assignee
Araclón Biotech, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Araclón Biotech, S.L. filed Critical Araclón Biotech, S.L.
Publication of CY1109454T1 publication Critical patent/CY1109454T1/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

Abstract

Η εφεύρεση σχετίζεται με τη χρήση αντισωμάτων στην παρασκευή ενός φαρμάκου για τη θεραπεία της νόσου του Αλτσχάϊμερ. Πιο συγκεκριμένα, η εφεύρεση σχετίζεται με τη χρήση ενός αντισώματος το οποίο αναγνωρίζει συγκεκριμένα οποιανδήποτε από τις βασικές παραλλαγές του πεπτιδίου βήτα-αμυλοειδούς Αβ40 και Αβ42, κατά την ετοιμασία ενός φαρμάκου το οποίο χρησιμοποιείται για την πρόληψη και/ή τη θεραπεία της νόσου του Αλτσχάϊμερ.
CY20091101026T 2003-05-08 2009-10-02 Θεραπεια για τη νοσο του αλτσχαϊμερ και της αγγειακης εγκεφαλικης αμυλοειδοπαθειας CY1109454T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200301054A ES2246105B1 (es) 2003-05-08 2003-05-08 Uso de anticuerpos para el tratamiento de enfermedades amiloideas.
EP04730882A EP1623719B1 (en) 2003-05-08 2004-05-03 Treatment of alzheimer's disease and cerebral amyloid angiopathy

Publications (1)

Publication Number Publication Date
CY1109454T1 true CY1109454T1 (el) 2014-08-13

Family

ID=32982086

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20091101026T CY1109454T1 (el) 2003-05-08 2009-10-02 Θεραπεια για τη νοσο του αλτσχαϊμερ και της αγγειακης εγκεφαλικης αμυλοειδοπαθειας

Country Status (19)

Country Link
US (6) US20090162362A1 (el)
EP (5) EP1623719B1 (el)
JP (5) JP2006525288A (el)
CN (2) CN101264326A (el)
AT (1) ATE435024T1 (el)
AU (2) AU2004237373A1 (el)
BR (1) BRPI0410684A (el)
CA (1) CA2524571C (el)
CY (1) CY1109454T1 (el)
DE (1) DE602004021797D1 (el)
DK (3) DK1623719T3 (el)
ES (6) ES2246177B1 (el)
IL (8) IL171651A (el)
MX (1) MXPA05010914A (el)
PL (3) PL1623719T3 (el)
PT (3) PT2075007E (el)
RU (2) RU2385161C2 (el)
SI (1) SI1623719T1 (el)
WO (1) WO2004098631A1 (el)

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US7927594B2 (en) 2004-07-30 2011-04-19 Rinat Neuroscience Corp. Antibodies directed against amyloid-beta peptide
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US8691224B2 (en) 2005-11-30 2014-04-08 Abbvie Inc. Anti-Aβ globulomer 5F7 antibodies
KR20180058863A (ko) 2005-11-30 2018-06-01 애브비 인코포레이티드 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의 용도
KR101591223B1 (ko) 2005-12-12 2016-02-04 에이씨 이뮨 에스.에이. 치료적 특성을 갖는 베타 1-42 특이적인 단일클론성 항체
PL2046833T3 (pl) 2006-07-14 2014-01-31 Ac Immune Sa Humanizowane przeciwciało przeciw amyloidowi beta
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
US20100311767A1 (en) 2007-02-27 2010-12-09 Abbott Gmbh & Co. Kg Method for the treatment of amyloidoses
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
DK2142514T3 (da) 2007-04-18 2015-03-23 Probiodrug Ag Thioureaderivater som glutaminylcyclase-inhibitorer
US8048420B2 (en) 2007-06-12 2011-11-01 Ac Immune S.A. Monoclonal antibody
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SG178809A1 (en) * 2007-10-05 2012-03-29 Genentech Inc Use of anti-amyloid beta antibody in ocular diseases
SI2238166T1 (sl) * 2007-10-05 2014-03-31 Genentech, Inc. Uporaba protitelesa proti amiloidu beta pri očesnih bolezni
EP2149380A1 (en) * 2008-07-29 2010-02-03 Medivet Pharma, S.L. Veterinary immunotherapy compositions for the Aged Related Cognitive Dysfunction.
EP2258398A1 (en) * 2009-05-26 2010-12-08 Araclón Biotech, S. L. Albumin-amyloid peptide conjugates and uses thereof
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EP2542549B1 (en) 2010-03-03 2016-05-11 Probiodrug AG Inhibitors of glutaminyl cyclase
EA022420B1 (ru) 2010-03-10 2015-12-30 Пробиодруг Аг Гетероциклические ингибиторы глутаминилциклазы (qc, ec 2.3.2.5)
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JP5945532B2 (ja) 2010-04-21 2016-07-05 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤としてのベンゾイミダゾール誘導体
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Also Published As

Publication number Publication date
EP2075007B9 (en) 2013-09-04
AU2011200170A1 (en) 2011-02-03
ES2329369T3 (es) 2009-11-25
IL207876A0 (en) 2011-07-31
IL207875A (en) 2013-02-28
IL207879A0 (en) 2011-07-31
PT2356996E (pt) 2013-08-23
IL207881A (en) 2013-02-28
IL171651A (en) 2011-11-30
JP2016065100A (ja) 2016-04-28
IL207880A0 (en) 2011-07-31
EP2356996B9 (en) 2013-08-28
ES2246105A1 (es) 2006-02-01
JP2014129389A (ja) 2014-07-10
MXPA05010914A (es) 2006-03-21
RU2005134351A (ru) 2006-04-27
CN101264326A (zh) 2008-09-17
ES2246178B1 (es) 2007-03-01
EP2305286A2 (en) 2011-04-06
IL207876A (en) 2013-03-24
EP2075007A2 (en) 2009-07-01
ES2423281T3 (es) 2013-09-19
IL207881A0 (en) 2011-07-31
IL207880A (en) 2013-02-28
EP2305286A3 (en) 2011-11-09
EP2356996B1 (en) 2013-06-26
PL2356996T3 (pl) 2013-09-30
IL207877A0 (en) 2011-07-31
BRPI0410684A (pt) 2006-06-20
CN1784240A (zh) 2006-06-07
RU2526155C2 (ru) 2014-08-20
JP2006525288A (ja) 2006-11-09
ES2246105B1 (es) 2007-03-01
US20170260234A1 (en) 2017-09-14
US20090162362A1 (en) 2009-06-25
WO2004098631A1 (es) 2004-11-18
DK2356996T5 (da) 2013-08-26
ES2246178A1 (es) 2006-02-01
EP2356996A1 (en) 2011-08-17
CA2524571A1 (en) 2004-11-18
AU2004237373A1 (en) 2004-11-18
RU2009148539A (ru) 2011-06-27
JP2012006967A (ja) 2012-01-12
IL207878A0 (en) 2011-07-31
IL207875A0 (en) 2011-07-31
DK2356996T3 (da) 2013-07-22
RU2385161C2 (ru) 2010-03-27
IL207879A (en) 2013-02-28
PL2075007T3 (pl) 2013-09-30
ES2423590T3 (es) 2013-09-23
IL207877A (en) 2013-03-24
AU2011200170C1 (en) 2012-03-22
DE602004021797D1 (de) 2009-08-13
CA2524571C (en) 2017-01-10
EP1623719A1 (en) 2006-02-08
EP2082747A3 (en) 2010-01-13
US20200140488A1 (en) 2020-05-07
EP2075007B1 (en) 2013-05-22
EP2082747A2 (en) 2009-07-29
US20110262458A1 (en) 2011-10-27
EP2075007A3 (en) 2009-11-11
PL1623719T3 (pl) 2010-11-30
DK1623719T3 (da) 2009-11-09
SI1623719T1 (sl) 2009-12-31
DK2075007T3 (da) 2013-07-29
ES2246177A1 (es) 2006-02-01
ATE435024T1 (de) 2009-07-15
EP1623719B1 (en) 2009-07-01
JP2018119011A (ja) 2018-08-02
IL207878A (en) 2013-02-28
ES2246177B1 (es) 2007-03-01
AU2011200170B2 (en) 2011-09-01
US20210214394A1 (en) 2021-07-15
PT2075007E (pt) 2013-08-23
PT1623719E (pt) 2009-10-08
US20140044725A1 (en) 2014-02-13

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