JP2006523463A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006523463A5 JP2006523463A5 JP2006513124A JP2006513124A JP2006523463A5 JP 2006523463 A5 JP2006523463 A5 JP 2006523463A5 JP 2006513124 A JP2006513124 A JP 2006513124A JP 2006513124 A JP2006513124 A JP 2006513124A JP 2006523463 A5 JP2006523463 A5 JP 2006523463A5
- Authority
- JP
- Japan
- Prior art keywords
- rna
- solid support
- solution
- biological material
- lithium salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007787 solid Substances 0.000 claims 16
- 238000000034 method Methods 0.000 claims 15
- 239000012620 biological material Substances 0.000 claims 10
- 229910003002 lithium salt Inorganic materials 0.000 claims 10
- 159000000002 lithium salts Chemical class 0.000 claims 10
- 238000005406 washing Methods 0.000 claims 9
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 8
- 230000009089 cytolysis Effects 0.000 claims 8
- 150000007523 nucleic acids Chemical class 0.000 claims 7
- 102000039446 nucleic acids Human genes 0.000 claims 7
- 108020004707 nucleic acids Proteins 0.000 claims 7
- 239000000203 mixture Substances 0.000 claims 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 4
- 238000009472 formulation Methods 0.000 claims 4
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims 4
- 239000000377 silicon dioxide Substances 0.000 claims 4
- 239000000872 buffer Substances 0.000 claims 3
- 239000002738 chelating agent Substances 0.000 claims 3
- 238000010828 elution Methods 0.000 claims 3
- 239000006166 lysate Substances 0.000 claims 3
- 238000010532 solid phase synthesis reaction Methods 0.000 claims 3
- 239000012535 impurity Substances 0.000 claims 2
- AMXOYNBUYSYVKV-UHFFFAOYSA-M lithium bromide Chemical compound [Li+].[Br-] AMXOYNBUYSYVKV-UHFFFAOYSA-M 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 1
- 239000006172 buffering agent Substances 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000003638 chemical reducing agent Substances 0.000 claims 1
- 239000000344 soap Substances 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- PBYZMCDFOULPGH-UHFFFAOYSA-N tungstate Chemical compound [O-][W]([O-])(=O)=O PBYZMCDFOULPGH-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/418,194 | 2003-04-16 | ||
| US10/418,194 US7148343B2 (en) | 2001-10-12 | 2003-04-16 | Compositions and methods for using a solid support to purify RNA |
| PCT/US2004/012033 WO2004094635A2 (en) | 2003-04-16 | 2004-04-15 | Compositions and methods for using a solid support to purify rna |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010181955A Division JP2010263919A (ja) | 2003-04-16 | 2010-08-16 | 固体支持体を使用してrnaを精製するための、組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006523463A JP2006523463A (ja) | 2006-10-19 |
| JP2006523463A5 true JP2006523463A5 (enExample) | 2007-06-07 |
| JP4804347B2 JP4804347B2 (ja) | 2011-11-02 |
Family
ID=33309522
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006513124A Expired - Lifetime JP4804347B2 (ja) | 2003-04-16 | 2004-04-15 | 固体支持体を使用してrnaを精製するための、組成物および方法 |
| JP2010181955A Pending JP2010263919A (ja) | 2003-04-16 | 2010-08-16 | 固体支持体を使用してrnaを精製するための、組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010181955A Pending JP2010263919A (ja) | 2003-04-16 | 2010-08-16 | 固体支持体を使用してrnaを精製するための、組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7148343B2 (enExample) |
| EP (1) | EP1618194B1 (enExample) |
| JP (2) | JP4804347B2 (enExample) |
| CA (1) | CA2522446C (enExample) |
| WO (1) | WO2004094635A2 (enExample) |
Families Citing this family (80)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2001516731A (ja) * | 1997-09-17 | 2001-10-02 | ジエントラ・システムズ・インコーポレーテツド | 核酸を単離するための装置および方法 |
| US7148343B2 (en) * | 2001-10-12 | 2006-12-12 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify RNA |
| US7893228B2 (en) * | 2001-10-12 | 2011-02-22 | Qiagen North American Holdings, Inc. | Compositions and methods for using a solid support to purify RNA |
| US20050032105A1 (en) * | 2001-10-12 | 2005-02-10 | Bair Robert Jackson | Compositions and methods for using a solid support to purify DNA |
| US7482116B2 (en) | 2002-06-07 | 2009-01-27 | Dna Genotek Inc. | Compositions and methods for obtaining nucleic acids from sputum |
| EA009302B1 (ru) * | 2003-05-20 | 2007-12-28 | Инвестиген, Инк. | Система обнаружения полинуклеотидов |
| JP2006528482A (ja) * | 2003-07-24 | 2006-12-21 | キアゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 核酸の逆転写及び/または増幅方法 |
| JP4435787B2 (ja) * | 2003-12-16 | 2010-03-24 | キアジェン ノース アメリカン ホールディングス,インコーポレイティド | タンパク質を変性させるための処方物および方法 |
| US7824855B2 (en) * | 2004-03-26 | 2010-11-02 | Fujifilm Corporation | Method for selectively separating and purifying RNA and method for separating and purifying nucleic acid |
| US20060099567A1 (en) * | 2004-04-08 | 2006-05-11 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| US20080176209A1 (en) * | 2004-04-08 | 2008-07-24 | Biomatrica, Inc. | Integration of sample storage and sample management for life science |
| BRPI0509694A (pt) * | 2004-04-08 | 2007-10-09 | Biomatrica Inc | integração de armazenamento de amostra e administração de amostra para ciências biológicas |
| US20050277121A1 (en) * | 2004-06-11 | 2005-12-15 | Ambion, Inc. | Crude biological derivatives competent for nucleic acid detection |
| EP1809744B1 (en) * | 2004-11-05 | 2018-06-06 | QIAGEN North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
| EP1690938A1 (de) * | 2005-02-11 | 2006-08-16 | Qiagen GmbH | Verfahren zur Isolierung von Nukleinsäuren, wobei die Nukleinsäuren bei erhöhter Temperatur an einer Matrix immobilisiert werden |
| US20100311041A1 (en) * | 2005-06-14 | 2010-12-09 | Statens Serum Institut | Pcr diagnostics of dermatophytes and other pathogenic fungi |
| US20060286557A1 (en) * | 2005-06-15 | 2006-12-21 | Basehore Lee S | Combined lysis and PCR buffer |
| US20070015165A1 (en) * | 2005-07-13 | 2007-01-18 | Sigma-Aldrich Co. | Method for the isolation of RNA from biological sources |
| US20070092403A1 (en) * | 2005-10-21 | 2007-04-26 | Alan Wirbisky | Compact apparatus, compositions and methods for purifying nucleic acids |
| US20070202511A1 (en) * | 2006-02-28 | 2007-08-30 | Sigma-Aldrich Co. | Methods and compositions for the rapid isolation of small RNA molecules |
| GB0604973D0 (en) * | 2006-03-11 | 2006-04-19 | Central Science Lab Csl Of San | Purification method and kit |
| KR100785010B1 (ko) * | 2006-04-06 | 2007-12-11 | 삼성전자주식회사 | 수소 결합을 이용하여 고체 지지체의 친수성 표면 상에서핵산 정제 방법 및 장치 |
| US8097419B2 (en) | 2006-09-12 | 2012-01-17 | Longhorn Vaccines & Diagnostics Llc | Compositions and method for rapid, real-time detection of influenza A virus (H1N1) swine 2009 |
| US8080645B2 (en) | 2007-10-01 | 2011-12-20 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection/transport compositions and methods |
| US9481912B2 (en) | 2006-09-12 | 2016-11-01 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and identifying nucleic acid sequences in biological samples |
| EP2094846B8 (en) * | 2006-12-13 | 2013-10-16 | Roche Diagnostics GmbH | Use of tde for the isolation of nucleic acids |
| DE602007010986D1 (de) * | 2006-12-13 | 2011-01-13 | Roche Diagnostics Gmbh | Verwendung von acetalen zur isolation von nukleinsäuren |
| US20100015628A1 (en) * | 2007-02-28 | 2010-01-21 | Ge Healthcare Bio-Sciences Corp. | Ambient temperature stable chemical/biological reagents on membranes or filters |
| KR101443218B1 (ko) * | 2007-08-16 | 2014-09-24 | 삼성전자주식회사 | 코스모트로픽 염을 이용한 고체 지지체에서의 rna 정제방법 |
| US9683256B2 (en) | 2007-10-01 | 2017-06-20 | Longhorn Vaccines And Diagnostics, Llc | Biological specimen collection and transport system |
| US20090053704A1 (en) * | 2007-08-24 | 2009-02-26 | Natalia Novoradovskaya | Stabilization of nucleic acids on solid supports |
| US11041215B2 (en) | 2007-08-24 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | PCR ready compositions and methods for detecting and identifying nucleic acid sequences |
| EP3058954B1 (en) | 2007-08-27 | 2017-03-01 | Longhorn Vaccines and Diagnostics, LLC | Immunogenic compositions and methods |
| US10004799B2 (en) | 2007-08-27 | 2018-06-26 | Longhorn Vaccines And Diagnostics, Llc | Composite antigenic sequences and vaccines |
| US8357296B2 (en) | 2007-09-24 | 2013-01-22 | Emd Millipore Corporation | Centrifugal filter |
| ES2552858T3 (es) | 2007-10-01 | 2015-12-02 | Longhorn Vaccines And Diagnostics, Llc | Recogida de muestras biológicas y sistema de transporte y métodos de uso |
| US11041216B2 (en) | 2007-10-01 | 2021-06-22 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for detecting and quantifying nucleic acid sequences in blood samples |
| KR101432034B1 (ko) * | 2007-11-16 | 2014-08-21 | 삼성전자주식회사 | 코스모트로픽 염을 이용한 고체 지지체에서의 작은 rna분리 방법 |
| US7871764B1 (en) * | 2008-03-18 | 2011-01-18 | The United States Of America As Represented By The United States Department Of Energy | Universal nucleic acids sample preparation method for cells, spores and their mixture |
| TW201006517A (en) * | 2008-05-22 | 2010-02-16 | Asahi Kasei Medical Co Ltd | Filtration method |
| EP2163620A1 (de) * | 2008-09-03 | 2010-03-17 | Qiagen GmbH | Verfahren zum Isolieren und Reinigen von Nukleinsäuren |
| DE102008047790A1 (de) * | 2008-09-17 | 2010-04-15 | Qiagen Gmbh | Verfahren zur Normierung des Gehalts von Biomolekülen in einer Probe |
| EP2175020A1 (en) | 2008-10-13 | 2010-04-14 | Roche Diagnostics GmbH | Reduction of RNase activity in complex fluidic samples |
| WO2010120874A2 (en) | 2009-04-14 | 2010-10-21 | Chimeros, Inc. | Chimeric therapeutics, compositions, and methods for using same |
| WO2012018638A2 (en) * | 2010-07-26 | 2012-02-09 | Biomatrica, Inc. | Compositions for stabilizing dna, rna and proteins in blood and other biological samples during shipping and storage at ambient temperatures |
| EP2598661B1 (en) * | 2010-07-26 | 2017-09-27 | Biomatrica, INC. | Compositions for stabilizing dna, rna and proteins in saliva and other biological samples during shipping and storage at ambient temperatures |
| US9255293B2 (en) * | 2010-11-01 | 2016-02-09 | Gen-Probe Incorporated | Integrated capture and amplification of target nucleic acid for sequencing |
| GB201103363D0 (en) * | 2011-02-28 | 2011-04-13 | Ge Healthcare Uk Ltd | Sample preservation method and sample application substrate |
| MX347611B (es) | 2011-06-19 | 2017-05-04 | Abogen Inc | Dispositivos, soluciones y metodos para recoleccion de muestras. |
| US9304070B2 (en) | 2011-07-13 | 2016-04-05 | Emd Millipore Corporation | All-in-one sample preparation device and method |
| AU2012305714A1 (en) | 2011-09-09 | 2014-03-27 | Biomed Realty, L.P. | Methods and compositions for controlling assembly of viral proteins |
| EP3494989B1 (en) | 2012-01-26 | 2025-07-16 | Longhorn Vaccines and Diagnostics, LLC | Composite antigenic sequences and vaccines |
| EP2820157B1 (en) | 2012-03-02 | 2019-05-01 | Winthrop-University Hospital | Method for using probe based pcr detection to measure the levels of circulating demethylated beta cell derived dna as a measure of beta cell loss in diabetes |
| CA2868805C (en) * | 2012-03-28 | 2018-09-04 | Longhorn Vaccines And Diagnostics, Llc | Compositions and methods for the collection and isolation of nucleic acids from biological specimens |
| WO2014065395A1 (ja) | 2012-10-26 | 2014-05-01 | 株式会社カネカ | Rna調製法 |
| EP3249054A1 (en) | 2012-12-20 | 2017-11-29 | Biomatrica, INC. | Formulations and methods for stabilizing pcr reagents |
| RU2717644C2 (ru) | 2014-03-07 | 2020-03-24 | ДиЭнЭй ГЕНОТЕК ИНК. | Способ, композиция и набор для стабилизации дезоксирибонуклеиновых кислот в биологических образцах |
| EP3942931A1 (en) | 2014-06-10 | 2022-01-26 | Biomatrica, INC. | Stabilization of thrombocytes at ambient temperatures |
| EP3218480A1 (en) | 2014-11-14 | 2017-09-20 | Corning Incorporated | Methods and kits for post-ivt rna purification |
| US10968443B2 (en) * | 2014-12-31 | 2021-04-06 | The Rockefeller University | Method of RNA isolation from clinical samples |
| EP3061822A1 (en) * | 2015-02-25 | 2016-08-31 | QIAGEN GmbH | Method for concentrating, isolating and/or purifying nucleic acids from highly diluted aqueous samples |
| GB201504459D0 (en) * | 2015-03-17 | 2015-04-29 | Moorlodge Biotech Ventures Ltd | Isolation of DNA |
| CA2985652C (en) | 2015-05-14 | 2020-03-10 | Gerald W. FISHER | Rapid methods for the extraction of nucleic acids from biological samples |
| KR20250047404A (ko) | 2015-12-08 | 2025-04-03 | 바이오매트리카 인코포레이티드 | 적혈구 침강 속도의 감소 |
| GB201609115D0 (en) * | 2016-05-24 | 2016-07-06 | Moorlodge Biotech Ventures Ltd | Isolating nucleic acids |
| US11112418B1 (en) * | 2016-07-29 | 2021-09-07 | Labrador Diagnostics Llc | Systems and methods for multi-analysis |
| SI3568475T1 (sl) * | 2017-01-16 | 2023-05-31 | Spectrum Solutions L. L. C. | Raztopina za ohranjanje nukleinske kisline in načini uporabe |
| EP3630971A1 (en) * | 2017-05-22 | 2020-04-08 | QIAGEN Healthcare Biotechnologies Systems Limited | Improvements in the recovery of nucleic acids from solid supports |
| CN108130325B (zh) * | 2018-02-02 | 2024-06-18 | 苏州优卡新材料科技有限公司 | 一种核糖核酸提取用无机材料滤芯的高效纯化柱 |
| CN108456674A (zh) * | 2018-03-26 | 2018-08-28 | 深圳市展行生物有限公司 | 一种Total RNA提取试剂及其制备方法 |
| CN109343143A (zh) * | 2018-10-09 | 2019-02-15 | 中国地质科学院矿产资源研究所 | 一种基于植物中锂元素含量预测隐伏锂矿床的方法 |
| WO2020085341A1 (ja) * | 2018-10-23 | 2020-04-30 | 東レ株式会社 | 核酸の回収方法及び核酸回収用のキット |
| CN113272314A (zh) * | 2018-11-14 | 2021-08-17 | 光谱解决方案有限责任公司 | Rna保存溶液及制造方法和使用方法 |
| MX2021005918A (es) | 2018-11-20 | 2021-08-24 | Spectrum Solutions Llc | Sistema de recoleccion de muestras que incluye una tapa de sellado y valvula. |
| US11701094B2 (en) | 2019-06-20 | 2023-07-18 | Spectrum Solutions L.L.C. | Sample collection system including valve and plug assemblies |
| US20230009972A1 (en) * | 2019-12-16 | 2023-01-12 | Qiagen Gmbh | Method for enriching vesicular rna |
| US12485166B2 (en) | 2020-02-06 | 2025-12-02 | Longhorn Vaccines And Diagnostics, Llc | Vaccines for the treatment and prevention of zoonotic infections |
| WO2021173983A1 (en) * | 2020-02-28 | 2021-09-02 | Somnio Global Holdings, Llc | Capillary assisted vitrification processes and materials for preservation of biological samples |
| GB2615470A (en) | 2020-10-20 | 2023-08-09 | Longhorn Vaccines & Diagnostics Llc | Immunogenic antigens |
| US20250258145A1 (en) * | 2022-04-20 | 2025-08-14 | Siemens Healthcare Diagnostics Inc. | Quantitation of alkylphenol ethoxylate compounds in aqueous samples |
Family Cites Families (64)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4483920A (en) * | 1982-05-17 | 1984-11-20 | Hahnemann University | Immobilization of message RNA directly from cells onto filter material |
| DE3639949A1 (de) * | 1986-11-22 | 1988-06-09 | Diagen Inst Molekularbio | Verfahren zur trennung von langkettigen nukleinsaeuren |
| US5599667A (en) * | 1987-03-02 | 1997-02-04 | Gen-Probe Incorporated | Polycationic supports and nucleic acid purification separation and hybridization |
| US4843155A (en) * | 1987-11-19 | 1989-06-27 | Piotr Chomczynski | Product and process for isolating RNA |
| US5234809A (en) * | 1989-03-23 | 1993-08-10 | Akzo N.V. | Process for isolating nucleic acid |
| US5010183A (en) * | 1989-07-07 | 1991-04-23 | Macfarlane Donald E | Process for purifying DNA and RNA using cationic detergents |
| DE4034036C2 (de) | 1990-10-26 | 1994-03-03 | Diagen Inst Molekularbio | Vorrichtung und Verfahren zur Isolierung von Nukleinsäuren aus Zellsuspensionen |
| CA2067711C (en) * | 1991-05-03 | 2000-08-08 | Daniel Lee Woodard | Solid phase extraction purification of dna |
| US5155018A (en) * | 1991-07-10 | 1992-10-13 | Hahnemann University | Process and kit for isolating and purifying RNA from biological sources |
| US5346994A (en) * | 1992-01-28 | 1994-09-13 | Piotr Chomczynski | Shelf-stable product and process for isolating RNA, DNA and proteins |
| AU6230594A (en) * | 1993-02-01 | 1994-08-29 | University Of Iowa Research Foundation, The | Quartenary amine surfactants and methods of using same in isolation of rna |
| DE4321904B4 (de) | 1993-07-01 | 2013-05-16 | Qiagen Gmbh | Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen |
| GB9314249D0 (en) | 1993-07-09 | 1993-08-18 | Proofname Ltd | Purification method and apparatus |
| US5637687A (en) * | 1993-08-31 | 1997-06-10 | Wiggins; James C. | Methods and compositions for isolating nucleic acids |
| ATE184013T1 (de) | 1994-06-14 | 1999-09-15 | Invitek Gmbh | Universelles verfahren zur isolierung und reinigung von nukleinsäuren aus extrem geringen mengen sowie sehr stark verunreinigten unterschiedlichsten ausgangsmaterialien |
| US6037465A (en) * | 1994-06-14 | 2000-03-14 | Invitek Gmbh | Universal process for isolating and purifying nucleic acids from extremely small amounts of highly contaminated various starting materials |
| GB9425138D0 (en) | 1994-12-12 | 1995-02-08 | Dynal As | Isolation of nucleic acid |
| WO1996030545A1 (en) * | 1995-03-24 | 1996-10-03 | Mitokor | Mutation detection by differential primer extension of mutant and wildtype target sequences |
| US5945515A (en) * | 1995-07-31 | 1999-08-31 | Chomczynski; Piotr | Product and process for isolating DNA, RNA and proteins |
| US5973137A (en) * | 1996-02-13 | 1999-10-26 | Gentra Systems, Inc. | Low pH RNA isolation reagents, method, and kit |
| JP3082908B2 (ja) * | 1996-07-12 | 2000-09-04 | 東洋紡績株式会社 | リボ核酸の単離方法 |
| DE69734263T2 (de) | 1996-07-12 | 2006-07-13 | Toyo Boseki K.K. | Verfahren zur Isolierung von Ribonucleinsäuren. |
| US5939259A (en) * | 1997-04-09 | 1999-08-17 | Schleicher & Schuell, Inc. | Methods and devices for collecting and storing clinical samples for genetic analysis |
| US6218531B1 (en) * | 1997-06-25 | 2001-04-17 | Promega Corporation | Method of isolating RNA |
| US5958677A (en) * | 1997-07-28 | 1999-09-28 | The New York Blood Center, Inc. | Method for purifying viral nucleic acids |
| US6207370B1 (en) * | 1997-09-02 | 2001-03-27 | Sequenom, Inc. | Diagnostics based on mass spectrometric detection of translated target polypeptides |
| JP2001516731A (ja) * | 1997-09-17 | 2001-10-02 | ジエントラ・システムズ・インコーポレーテツド | 核酸を単離するための装置および方法 |
| US5972613A (en) * | 1997-12-09 | 1999-10-26 | The Perkin-Elmer Corporation | Methods of nucleic acid isolation |
| DE19858447A1 (de) * | 1997-12-18 | 1999-07-01 | Invitek Gmbh | Verfahren zur Isolierung von kurz- und langkettigen Nukleinsäuren |
| JPH11196869A (ja) * | 1998-01-19 | 1999-07-27 | Toyobo Co Ltd | リボ核酸の単離方法 |
| ZA99493B (en) * | 1998-01-30 | 1999-07-22 | Akzo Nobel Nv | Method for the isolation of nucleic acid. |
| WO1999039009A1 (en) | 1998-02-02 | 1999-08-05 | Gentra Systems, Inc. | Processes for isolating, amplifying and characterizing dna |
| US6090593A (en) * | 1998-05-13 | 2000-07-18 | The United States Of America As Represented By The Secretary Of The Air Force | Isolation of expressed genes in microorganisms |
| US6204375B1 (en) * | 1998-07-31 | 2001-03-20 | Ambion, Inc. | Methods and reagents for preserving RNA in cell and tissue samples |
| JP3183458B2 (ja) * | 1998-08-12 | 2001-07-09 | 農林水産省国際農林水産業研究センター所長 | 植物の転写因子をコードする遺伝子 |
| US6777210B1 (en) * | 1998-09-24 | 2004-08-17 | Ambion, Inc. | Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1 |
| US6958392B2 (en) * | 1998-10-09 | 2005-10-25 | Whatman, Inc. | Methods for the isolation of nucleic acids and for quantitative DNA extraction and detection for leukocyte evaluation in blood products |
| DE19856064C2 (de) * | 1998-12-04 | 2000-11-30 | Invitek Gmbh | Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien |
| US6270970B1 (en) * | 1999-05-14 | 2001-08-07 | Promega Corporation | Mixed-bed solid phase and its use in the isolation of nucleic acids |
| US20060276629A9 (en) * | 1999-12-17 | 2006-12-07 | Hildebrand William H | Purification and characterization of soluble human HLA proteins |
| JP3922420B2 (ja) * | 2000-04-18 | 2007-05-30 | 東洋紡績株式会社 | 改良されたリボ核酸の単離方法 |
| US6919307B2 (en) * | 2000-11-01 | 2005-07-19 | Praecis Pharmaceuticals, Inc. | Therapeutic agents and methods of use thereof for the modulation of angiogenesis |
| US6602718B1 (en) * | 2000-11-08 | 2003-08-05 | Becton, Dickinson And Company | Method and device for collecting and stabilizing a biological sample |
| US6503716B1 (en) * | 2000-11-28 | 2003-01-07 | Pe Corporation (Ny) | Compositions and methods for extracting a nucleic acid |
| US6818398B2 (en) * | 2000-12-29 | 2004-11-16 | The University Of Chicago | Column device for isolation and labeling of nucleic acids |
| US20020106686A1 (en) * | 2001-01-09 | 2002-08-08 | Mckernan Kevin J. | Methods and reagents for the isolation of nucleic acids |
| AU2002211719B2 (en) * | 2001-10-12 | 2007-06-14 | Qiagen North American Holdings, Inc. | Compositions and methods for using a solid support to purify RNA |
| US20050032105A1 (en) * | 2001-10-12 | 2005-02-10 | Bair Robert Jackson | Compositions and methods for using a solid support to purify DNA |
| US7148343B2 (en) * | 2001-10-12 | 2006-12-12 | Gentra Systems, Inc. | Compositions and methods for using a solid support to purify RNA |
| US7893228B2 (en) * | 2001-10-12 | 2011-02-22 | Qiagen North American Holdings, Inc. | Compositions and methods for using a solid support to purify RNA |
| DK1442045T3 (da) * | 2001-11-06 | 2009-02-09 | Cortex Biochem Inc | Isolering og oprensning af nukleinsyrer |
| JP4220164B2 (ja) * | 2002-02-06 | 2009-02-04 | 東洋紡績株式会社 | 核酸の精製方法および当該方法に用いる核酸抽出用溶液ならびに核酸精製用試薬キット |
| DE10231659B4 (de) * | 2002-07-12 | 2006-01-19 | Preanalytix Gmbh | Zusammensetzung zum Binden von Nukleinsäure an eine Festphase |
| GB0225197D0 (en) * | 2002-10-30 | 2002-12-11 | Univ Sheffield | Surface |
| WO2004058300A1 (en) * | 2002-12-20 | 2004-07-15 | E.I. Du Pont De Nemours And Company | Sequences diagnostic for foot and mouth disease |
| GB0230102D0 (en) * | 2002-12-23 | 2003-01-29 | Spinox Ltd | Apparatus and method for storing proteins |
| WO2005003346A1 (en) * | 2003-06-06 | 2005-01-13 | Applera Corporation | Purification device for ribonucleic acid in large volumes, and method |
| JP4435787B2 (ja) * | 2003-12-16 | 2010-03-24 | キアジェン ノース アメリカン ホールディングス,インコーポレイティド | タンパク質を変性させるための処方物および方法 |
| EP1809744B1 (en) * | 2004-11-05 | 2018-06-06 | QIAGEN North American Holdings, Inc. | Compositions and methods for purifying nucleic acids from stabilization reagents |
| KR100691372B1 (ko) * | 2005-10-19 | 2007-03-12 | 삼성전기주식회사 | 신뢰성이 확보된 전해액을 포함하는 전기 습윤 장치 |
| US20070092403A1 (en) * | 2005-10-21 | 2007-04-26 | Alan Wirbisky | Compact apparatus, compositions and methods for purifying nucleic acids |
| US20070141583A1 (en) * | 2005-12-20 | 2007-06-21 | Weiwei Li | Methods of rapid chromatin immunoprecipitation |
| US7538190B2 (en) * | 2006-02-17 | 2009-05-26 | Polychip Pharmaceuticals Pty Ltd | Methods for the synthesis of two or more dicarba bridges in organic compounds |
| EP2035540A2 (en) * | 2006-06-15 | 2009-03-18 | Stratagene | System for isolating biomolecules from a sample |
-
2003
- 2003-04-16 US US10/418,194 patent/US7148343B2/en not_active Expired - Lifetime
-
2004
- 2004-04-15 EP EP04760008.5A patent/EP1618194B1/en not_active Expired - Lifetime
- 2004-04-15 CA CA2522446A patent/CA2522446C/en not_active Expired - Lifetime
- 2004-04-15 WO PCT/US2004/012033 patent/WO2004094635A2/en not_active Ceased
- 2004-04-15 JP JP2006513124A patent/JP4804347B2/ja not_active Expired - Lifetime
-
2006
- 2006-10-30 US US11/589,364 patent/US7767804B2/en not_active Expired - Lifetime
-
2010
- 2010-08-16 JP JP2010181955A patent/JP2010263919A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006523463A5 (enExample) | ||
| JP5325448B2 (ja) | 固相を用いての核酸分子の単離および精製 | |
| JP4036625B2 (ja) | 二本鎖/単鎖核酸構造物の分離方法 | |
| JP2007529229A5 (enExample) | ||
| US10731147B2 (en) | Methods and kits for post-IVT RNA purification | |
| JP2008263982A5 (enExample) | ||
| CN111057704B (zh) | 一种石蜡切片样本dna提取的脱蜡裂解结合液、试剂盒及方法 | |
| JP2011530278A (ja) | 核酸の単離 | |
| CA2549985A1 (en) | Formulations and methods for denaturing proteins | |
| JP2005505305A5 (enExample) | ||
| US20090005543A1 (en) | Protein-refolding material | |
| JP2002501759A (ja) | 核酸の改善された単離方法 | |
| CN118240814B (zh) | 一种完全区分dna和rna的纯化方法及rna纯化试剂盒 | |
| CN106754890B (zh) | 一种病毒rna的提取试剂盒和提取方法 | |
| CN102115739B (zh) | 分离核酸的方法、试剂及套组 | |
| WO2009100172A1 (en) | Isolation of dna, rna and protein from a single sample | |
| US7803935B2 (en) | Nucleic acid adsorption under low-salt conditions | |
| US8513405B2 (en) | Reagent, chaotropic agent, and reagent kit for and applications of isolating nucleic acid by use of magnetic cellulose material | |
| Mi et al. | Comparison of different DNA extraction methods for forensic samples | |
| WO2005093065A1 (en) | Improved method of isolating nucleic acids | |
| JP2008506932A5 (enExample) | ||
| JP2006526591A (ja) | 核酸または核酸含有種の濃縮及び/または単離方法 | |
| EP1627060A1 (de) | Verfahren zur nukleinsäureextraktion | |
| Mitra et al. | High-performance catalytic chromatography: The adapter approach | |
| EP4229215A1 (en) | Methods and kits for nucleic acid purification |