JP2006523091A - ヒト胚性幹細胞の心筋細胞への分化 - Google Patents

ヒト胚性幹細胞の心筋細胞への分化 Download PDF

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JP2006523091A
JP2006523091A JP2006503961A JP2006503961A JP2006523091A JP 2006523091 A JP2006523091 A JP 2006523091A JP 2006503961 A JP2006503961 A JP 2006503961A JP 2006503961 A JP2006503961 A JP 2006503961A JP 2006523091 A JP2006523091 A JP 2006523091A
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ママリー,クリスティン・リンゼイ
ドゥーフェンダンス,ペトルス・アドリアヌス・フレデリック・マリーア
テルトーレン,レオン・ヘラルドゥス・ヨーゼフ
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イーエス・セル・インターナショナル・プライヴェート・リミテッド
ネザーランズ・インスティテュート・フォール・オントヴィッケリングスビオロヒー
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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JP2006503961A 2003-03-11 2004-03-11 ヒト胚性幹細胞の心筋細胞への分化 Pending JP2006523091A (ja)

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Application Number Priority Date Filing Date Title
AU2003901099A AU2003901099A0 (en) 2003-03-11 2003-03-11 Methods of inducing differentiation of stem cells
PCT/AU2004/000302 WO2004081205A1 (en) 2003-03-11 2004-03-11 Differentiation of human embryonic stem cells to cardiomyocytes

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JP2006523091A5 JP2006523091A5 (enExample) 2007-05-24

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US (1) US20070161107A1 (enExample)
EP (1) EP1608740A4 (enExample)
JP (1) JP2006523091A (enExample)
AU (1) AU2003901099A0 (enExample)
CA (1) CA2518508A1 (enExample)
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Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010047133A1 (ja) * 2008-10-24 2010-04-29 株式会社クラレ 細胞保存方法、及び細胞輸送方法
WO2010134606A1 (ja) 2009-05-22 2010-11-25 学校法人 東京女子医科大学 胚性幹細胞或いは人工多能性幹細胞の分化誘導方法
JP2013531497A (ja) * 2010-06-13 2013-08-08 インスティチュート・オブ・バイオフィジックス,チャイニーズ・アカデミー・オブ・サイエンシズ 幹細胞から心筋細胞を調製するための方法および組成物ならびにその使用
JP2014525268A (ja) * 2011-08-30 2014-09-29 ザ ジェイ. デヴィッド グラッドストーン インスティテューツ 心筋細胞を生成するための方法
WO2015025958A1 (ja) * 2013-08-23 2015-02-26 国立大学法人大阪大学 ペースメーカー組織片の製造方法
US11339371B2 (en) 2012-07-23 2022-05-24 Institute Of Biophysics, Chinese Academy Of Sciences Method for inducing pluripotent stem cells to differentiate into ventricular myocytes in vitro
WO2024162286A1 (ja) 2023-01-31 2024-08-08 富士フイルム株式会社 薬剤の評価方法、試薬およびキット

Families Citing this family (29)

* Cited by examiner, † Cited by third party
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IL159580A0 (en) 2001-07-12 2004-06-01 Geron Corp Cells of the cardiomyocyte lineage produced from human pluripotent stem cells
US7732199B2 (en) 2001-07-12 2010-06-08 Geron Corporation Process for making transplantable cardiomyocytes from human embryonic stem cells
US7452718B2 (en) 2004-03-26 2008-11-18 Geron Corporation Direct differentiation method for making cardiomyocytes from human embryonic stem cells
CA2569242A1 (en) * 2004-06-01 2005-12-15 Es Cell International Pte Ltd Improved cardiomyocyte differentiation
KR20130099253A (ko) 2005-06-22 2013-09-05 제론 코포레이션 영장류 다능성 줄기 세포의 심근세포 계통 세포로의 분화
US8278104B2 (en) 2005-12-13 2012-10-02 Kyoto University Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2
KR101420740B1 (ko) 2005-12-13 2014-07-17 교또 다이가꾸 핵초기화 인자
US20090227032A1 (en) 2005-12-13 2009-09-10 Kyoto University Nuclear reprogramming factor and induced pluripotent stem cells
US8129187B2 (en) 2005-12-13 2012-03-06 Kyoto University Somatic cell reprogramming by retroviral vectors encoding Oct3/4. Klf4, c-Myc and Sox2
KR20090086260A (ko) * 2006-12-07 2009-08-11 테바 파마슈티컬 인더스트리즈 리미티드 미손상 골수 또는 미손상 제대 조직으로부터 조직 전구체 세포 및 성숙 조직 세포를 형성 및 증식시키는 방법
US20080300642A1 (en) * 2007-05-30 2008-12-04 Japan As Represented By President Of National Cardiovascular Center Regeneration treatment apparatus, operating method thereof, and regeneration treatment method
JP2008307007A (ja) 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
US9213999B2 (en) 2007-06-15 2015-12-15 Kyoto University Providing iPSCs to a customer
WO2009036220A2 (en) * 2007-09-12 2009-03-19 The Regents Of The University Of California Compositions and methods for improving the functional efficacy of stem cell-derived cardiomyocytes
KR101532442B1 (ko) 2007-12-10 2015-06-29 고쿠리츠 다이가쿠 호진 교토 다이가쿠 효율적인 핵 초기화 방법
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
SG188098A1 (en) 2008-01-30 2013-03-28 Geron Corp Synthetic surfaces for culturing stem cell derived cardiomyocytes
ES2690554T3 (es) 2008-03-17 2018-11-21 The Scripps Research Institute Enfoques químicos y genéticos combinados para la generación de células madre pluripotentes inducidas
ES2722198T3 (es) 2008-05-02 2019-08-08 Univ Kyoto Método de reprogramación nuclear
ES2645869T3 (es) 2008-12-17 2017-12-11 The Scripps Research Institute Generación y mantenimiento de células madre
ES2638464T3 (es) 2009-10-16 2017-10-20 The Scripps Research Institute Inducción de células pluripotentes
AU2011235212B2 (en) 2010-03-31 2014-07-31 The Scripps Research Institute Reprogramming cells
EP3399026B1 (en) 2010-06-14 2024-06-26 The Scripps Research Institute Reprogramming of cells to a new fate
CN106893692B (zh) 2010-12-22 2021-11-26 菲特治疗公司 用于单细胞分选与增强ipsc重新编程的细胞培养平台
EP2948542A4 (en) 2013-01-23 2016-07-13 Ronald Li MANIPULATED PHYSICAL ORIENTATION OF CARDIOMYOCYTES FROM STEM CELLS
US10087436B2 (en) 2014-02-06 2018-10-02 The Regents Of The University Of California Electrophysiologically mature cardiomyocytes and methods for making same
SG10201807292YA (en) 2014-03-04 2018-09-27 Fate Therapeutics Inc Improved reprogramming methods and cell culture platforms
AU2016338680B2 (en) 2015-10-16 2022-11-17 Fate Therapeutics, Inc. Platform for the induction and maintenance of ground state pluripotency
CN113662985B (zh) 2021-09-07 2022-06-24 北京中医药大学 具有促进干细胞定向分化为心肌细胞作用的中药组合物、中药有效组分组合物及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050026008A (ko) * 2002-07-26 2005-03-14 위스콘신 얼럼나이 리서어치 화운데이션 인간 배아 줄기 세포로부터의 기능성 심근 세포
WO2005054448A1 (en) * 2003-12-04 2005-06-16 Guhathakurta Dr Soma A novel process and method for deriving cardiomyocyte precursors from bone-marrow stem cells

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003010303A1 (en) * 2001-07-24 2003-02-06 Es Cell International Pte Ltd Methods of inducing differentiation of stem cells

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010047133A1 (ja) * 2008-10-24 2010-04-29 株式会社クラレ 細胞保存方法、及び細胞輸送方法
JPWO2010047133A1 (ja) * 2008-10-24 2012-03-22 株式会社クラレ 細胞保存方法、及び細胞輸送方法
WO2010134606A1 (ja) 2009-05-22 2010-11-25 学校法人 東京女子医科大学 胚性幹細胞或いは人工多能性幹細胞の分化誘導方法
JP2013531497A (ja) * 2010-06-13 2013-08-08 インスティチュート・オブ・バイオフィジックス,チャイニーズ・アカデミー・オブ・サイエンシズ 幹細胞から心筋細胞を調製するための方法および組成物ならびにその使用
US9273286B2 (en) 2010-06-13 2016-03-01 Institute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
US10590386B2 (en) 2010-06-13 2020-03-17 Insitute Of Biophysics, Chinese Academy Of Sciences Methods and compositions for preparing cardiomyocytes from stem cells and uses thereof
JP2014525268A (ja) * 2011-08-30 2014-09-29 ザ ジェイ. デヴィッド グラッドストーン インスティテューツ 心筋細胞を生成するための方法
US11339371B2 (en) 2012-07-23 2022-05-24 Institute Of Biophysics, Chinese Academy Of Sciences Method for inducing pluripotent stem cells to differentiate into ventricular myocytes in vitro
WO2015025958A1 (ja) * 2013-08-23 2015-02-26 国立大学法人大阪大学 ペースメーカー組織片の製造方法
WO2024162286A1 (ja) 2023-01-31 2024-08-08 富士フイルム株式会社 薬剤の評価方法、試薬およびキット
KR20250130369A (ko) 2023-01-31 2025-09-01 후지필름 가부시키가이샤 약제의 평가 방법, 시약 및 키트
EP4660316A1 (en) 2023-01-31 2025-12-10 FUJIFILM Corporation Drug evaluation method, reagent and kit

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GB2415437A (en) 2005-12-28
US20070161107A1 (en) 2007-07-12
EP1608740A1 (en) 2005-12-28
EP1608740A4 (en) 2007-05-09
GB0520673D0 (en) 2005-11-16
WO2004081205A1 (en) 2004-09-23
AU2003901099A0 (en) 2003-03-27
WO2004081205A8 (en) 2004-10-28
CA2518508A1 (en) 2004-09-23

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