JP2006517202A5 - - Google Patents
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- Publication number
- JP2006517202A5 JP2006517202A5 JP2006500307A JP2006500307A JP2006517202A5 JP 2006517202 A5 JP2006517202 A5 JP 2006517202A5 JP 2006500307 A JP2006500307 A JP 2006500307A JP 2006500307 A JP2006500307 A JP 2006500307A JP 2006517202 A5 JP2006517202 A5 JP 2006517202A5
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- dodeca
- trien
- tricyclo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000000034 method Methods 0.000 claims 12
- 239000003054 catalyst Substances 0.000 claims 8
- 150000001875 compounds Chemical class 0.000 claims 8
- 238000005984 hydrogenation reaction Methods 0.000 claims 7
- 239000002253 acid Substances 0.000 claims 5
- 125000003277 amino group Chemical group 0.000 claims 3
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims 1
- 150000004703 alkoxides Chemical class 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 150000001408 amides Chemical class 0.000 claims 1
- 125000003710 aryl alkyl group Chemical group 0.000 claims 1
- 125000002102 aryl alkyloxo group Chemical group 0.000 claims 1
- 125000002619 bicyclic group Chemical group 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 229910052799 carbon Inorganic materials 0.000 claims 1
- 150000001721 carbon Chemical group 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- LUGPKNSVKLHXDX-UHFFFAOYSA-N dodeca-6,8,10-trien-4-one Chemical compound CCCC(=O)CC=CC=CC=CC LUGPKNSVKLHXDX-UHFFFAOYSA-N 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical class 0.000 claims 1
- 125000004404 heteroalkyl group Chemical group 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- UKVIEHSSVKSQBA-UHFFFAOYSA-N methane;palladium Chemical compound C.[Pd] UKVIEHSSVKSQBA-UHFFFAOYSA-N 0.000 claims 1
- 125000002950 monocyclic group Chemical group 0.000 claims 1
- 125000002560 nitrile group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- MFRIHAYPQRLWNB-UHFFFAOYSA-N sodium tert-butoxide Chemical group [Na+].CC(C)(C)[O-] MFRIHAYPQRLWNB-UHFFFAOYSA-N 0.000 claims 1
- 239000002904 solvent Substances 0.000 claims 1
- 125000004963 sulfonylalkyl group Chemical group 0.000 claims 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44026603P | 2003-01-15 | 2003-01-15 | |
| PCT/IB2004/000152 WO2004063164A1 (en) | 2003-01-15 | 2004-01-08 | Process for the preparation of aryl fused polycyclic lactams |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006517202A JP2006517202A (ja) | 2006-07-20 |
| JP2006517202A5 true JP2006517202A5 (enExample) | 2006-10-12 |
Family
ID=32713537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2006500307A Withdrawn JP2006517202A (ja) | 2003-01-15 | 2004-01-08 | アリール縮合多環式ラクタムの製造のための方法 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20070066827A1 (enExample) |
| EP (1) | EP1587794A1 (enExample) |
| JP (1) | JP2006517202A (enExample) |
| KR (2) | KR20070087258A (enExample) |
| CN (1) | CN100363350C (enExample) |
| AR (1) | AR042855A1 (enExample) |
| AU (1) | AU2004203983A1 (enExample) |
| BR (1) | BRPI0406670A (enExample) |
| CA (1) | CA2513293A1 (enExample) |
| CL (1) | CL2004000041A1 (enExample) |
| IL (1) | IL169479A0 (enExample) |
| MX (1) | MXPA05007565A (enExample) |
| PL (1) | PL379373A1 (enExample) |
| RS (1) | RS20050513A (enExample) |
| RU (1) | RU2291862C2 (enExample) |
| TW (1) | TW200420286A (enExample) |
| WO (1) | WO2004063164A1 (enExample) |
| ZA (1) | ZA200505103B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003278510B8 (en) | 2002-11-25 | 2008-07-10 | Pfizer Products Inc. | Improved process for the preparation of 1,3-substituted indenes |
| RU2372323C1 (ru) * | 2008-04-15 | 2009-11-10 | Открытое акционерное общество Научно-производственное предприятие НИИПАВ (ОАО НПП НИИПАВ) | Способ получения высокомолекулярных аминов |
| EP2268639A2 (en) | 2008-05-22 | 2011-01-05 | Teva Pharmaceutical Industries Ltd. | Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate |
| US20090318695A1 (en) * | 2008-06-19 | 2009-12-24 | Vinod Kumar Kansal | Processes for the preparation of varenicline and intermediates thereof |
| EP2438054A1 (en) | 2009-06-22 | 2012-04-11 | Teva Pharmaceutical Industries Ltd. | Solid states forms of varenicline salts and processes for preparation thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1040211C (zh) * | 1993-08-05 | 1998-10-14 | 辛太克斯(美国)公司 | 基质金属蛋白酶抑制剂 |
| ME00459B (me) * | 1997-12-31 | 2011-10-10 | Pfizer Prod Inc | Aril fuzirana azapoliciklična jedinjenja |
| US6605610B1 (en) * | 1997-12-31 | 2003-08-12 | Pfizer Inc | Aryl fused azapolycyclic compounds |
| YU78303A (sh) * | 2001-04-20 | 2006-05-25 | Pfizer Products Inc. | Postupak za dobijanje 1,3-supstituisanih indena i azapolicikličnih jedinjenja sa pripojenim arilom |
-
2004
- 2004-01-08 EP EP04700747A patent/EP1587794A1/en not_active Withdrawn
- 2004-01-08 RU RU2005122406/04A patent/RU2291862C2/ru not_active IP Right Cessation
- 2004-01-08 MX MXPA05007565A patent/MXPA05007565A/es unknown
- 2004-01-08 PL PL379373A patent/PL379373A1/pl not_active Application Discontinuation
- 2004-01-08 WO PCT/IB2004/000152 patent/WO2004063164A1/en not_active Ceased
- 2004-01-08 CN CNB2004800022895A patent/CN100363350C/zh not_active Expired - Fee Related
- 2004-01-08 AU AU2004203983A patent/AU2004203983A1/en not_active Abandoned
- 2004-01-08 BR BR0406670-7A patent/BRPI0406670A/pt not_active IP Right Cessation
- 2004-01-08 JP JP2006500307A patent/JP2006517202A/ja not_active Withdrawn
- 2004-01-08 RS YUP-2005/0513A patent/RS20050513A/sr unknown
- 2004-01-08 KR KR1020077018129A patent/KR20070087258A/ko not_active Withdrawn
- 2004-01-08 US US10/547,619 patent/US20070066827A1/en not_active Abandoned
- 2004-01-08 KR KR1020057013036A patent/KR20050101177A/ko not_active Ceased
- 2004-01-08 CA CA002513293A patent/CA2513293A1/en not_active Abandoned
- 2004-01-12 CL CL200400041A patent/CL2004000041A1/es unknown
- 2004-01-14 AR ARP040100091A patent/AR042855A1/es not_active Application Discontinuation
- 2004-01-14 TW TW093100889A patent/TW200420286A/zh unknown
-
2005
- 2005-06-23 ZA ZA200505103A patent/ZA200505103B/en unknown
- 2005-06-30 IL IL169479A patent/IL169479A0/en unknown
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