KR20070087258A - 아릴 융합된 폴리시클릭 락탐의 제조 방법 - Google Patents
아릴 융합된 폴리시클릭 락탐의 제조 방법 Download PDFInfo
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- KR20070087258A KR20070087258A KR1020077018129A KR20077018129A KR20070087258A KR 20070087258 A KR20070087258 A KR 20070087258A KR 1020077018129 A KR1020077018129 A KR 1020077018129A KR 20077018129 A KR20077018129 A KR 20077018129A KR 20070087258 A KR20070087258 A KR 20070087258A
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- South Korea
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- compound
- acid
- dodeca
- tricyclo
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- -1 polycyclic lactams Chemical class 0.000 title abstract description 8
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- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 18
- 238000005984 hydrogenation reaction Methods 0.000 claims description 17
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 16
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- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 claims description 10
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- CUBCNYWQJHBXIY-UHFFFAOYSA-N benzoic acid;2-hydroxybenzoic acid Chemical compound OC(=O)C1=CC=CC=C1.OC(=O)C1=CC=CC=C1O CUBCNYWQJHBXIY-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44026603P | 2003-01-15 | 2003-01-15 | |
| US60/440,266 | 2003-01-15 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057013036A Division KR20050101177A (ko) | 2003-01-15 | 2004-01-08 | 아릴 융합된 폴리시클릭 락탐의 제조 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20070087258A true KR20070087258A (ko) | 2007-08-27 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020077018129A Withdrawn KR20070087258A (ko) | 2003-01-15 | 2004-01-08 | 아릴 융합된 폴리시클릭 락탐의 제조 방법 |
| KR1020057013036A Ceased KR20050101177A (ko) | 2003-01-15 | 2004-01-08 | 아릴 융합된 폴리시클릭 락탐의 제조 방법 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020057013036A Ceased KR20050101177A (ko) | 2003-01-15 | 2004-01-08 | 아릴 융합된 폴리시클릭 락탐의 제조 방법 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20070066827A1 (enExample) |
| EP (1) | EP1587794A1 (enExample) |
| JP (1) | JP2006517202A (enExample) |
| KR (2) | KR20070087258A (enExample) |
| CN (1) | CN100363350C (enExample) |
| AR (1) | AR042855A1 (enExample) |
| AU (1) | AU2004203983A1 (enExample) |
| BR (1) | BRPI0406670A (enExample) |
| CA (1) | CA2513293A1 (enExample) |
| CL (1) | CL2004000041A1 (enExample) |
| IL (1) | IL169479A0 (enExample) |
| MX (1) | MXPA05007565A (enExample) |
| PL (1) | PL379373A1 (enExample) |
| RS (1) | RS20050513A (enExample) |
| RU (1) | RU2291862C2 (enExample) |
| TW (1) | TW200420286A (enExample) |
| WO (1) | WO2004063164A1 (enExample) |
| ZA (1) | ZA200505103B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2284319C2 (ru) | 2002-11-25 | 2006-09-27 | Пфайзер Продактс Инк. | Усовершенствованный способ получения 1,3-замещенных инденов |
| RU2372323C1 (ru) * | 2008-04-15 | 2009-11-10 | Открытое акционерное общество Научно-производственное предприятие НИИПАВ (ОАО НПП НИИПАВ) | Способ получения высокомолекулярных аминов |
| WO2009143347A2 (en) | 2008-05-22 | 2009-11-26 | Teva Pharmaceutical Industries Ltd. | Varenicline tosylate, an intermediate in the preparation process of varenicline l-tartrate |
| WO2009155403A2 (en) * | 2008-06-19 | 2009-12-23 | Teva Pharmaceutical Industries Ltd. | Processes for the preparation of varenicline and intermediates thereof |
| RU2012102052A (ru) * | 2009-06-22 | 2013-11-20 | Тева Фармасьютикал Индастриз Лтд. | Твердые формы солей варениклина и способы их получения |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU222818B1 (hu) * | 1993-08-05 | 2003-11-28 | Syntex (U.S.A.) Inc. | Mátrix metalloproteáz inhibitor hatású indolszármazékok, előállításuk és a vegyületeket tartalmazó gyógyászati készítmények |
| US6605610B1 (en) * | 1997-12-31 | 2003-08-12 | Pfizer Inc | Aryl fused azapolycyclic compounds |
| TR200001840T2 (tr) * | 1997-12-31 | 2000-12-21 | Pfizer Products Inc. | Arile bağlı azopolisiklik bileşikler |
| PT1383733E (pt) * | 2001-04-20 | 2008-04-15 | Pfizer Prod Inc | Processo para a preparação de indenos 1,3-substituídos e compostos azapolicíclicos fundidos com arilo |
-
2004
- 2004-01-08 AU AU2004203983A patent/AU2004203983A1/en not_active Abandoned
- 2004-01-08 KR KR1020077018129A patent/KR20070087258A/ko not_active Withdrawn
- 2004-01-08 WO PCT/IB2004/000152 patent/WO2004063164A1/en not_active Ceased
- 2004-01-08 CA CA002513293A patent/CA2513293A1/en not_active Abandoned
- 2004-01-08 MX MXPA05007565A patent/MXPA05007565A/es unknown
- 2004-01-08 RU RU2005122406/04A patent/RU2291862C2/ru not_active IP Right Cessation
- 2004-01-08 RS YUP-2005/0513A patent/RS20050513A/sr unknown
- 2004-01-08 JP JP2006500307A patent/JP2006517202A/ja not_active Withdrawn
- 2004-01-08 BR BR0406670-7A patent/BRPI0406670A/pt not_active IP Right Cessation
- 2004-01-08 PL PL379373A patent/PL379373A1/pl not_active Application Discontinuation
- 2004-01-08 KR KR1020057013036A patent/KR20050101177A/ko not_active Ceased
- 2004-01-08 CN CNB2004800022895A patent/CN100363350C/zh not_active Expired - Fee Related
- 2004-01-08 EP EP04700747A patent/EP1587794A1/en not_active Withdrawn
- 2004-01-08 US US10/547,619 patent/US20070066827A1/en not_active Abandoned
- 2004-01-12 CL CL200400041A patent/CL2004000041A1/es unknown
- 2004-01-14 AR ARP040100091A patent/AR042855A1/es not_active Application Discontinuation
- 2004-01-14 TW TW093100889A patent/TW200420286A/zh unknown
-
2005
- 2005-06-23 ZA ZA200505103A patent/ZA200505103B/en unknown
- 2005-06-30 IL IL169479A patent/IL169479A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN100363350C (zh) | 2008-01-23 |
| RS20050513A (sr) | 2007-11-15 |
| CA2513293A1 (en) | 2004-07-29 |
| AR042855A1 (es) | 2005-07-06 |
| EP1587794A1 (en) | 2005-10-26 |
| RU2005122406A (ru) | 2006-01-27 |
| WO2004063164A8 (en) | 2005-05-26 |
| PL379373A1 (pl) | 2006-08-21 |
| BRPI0406670A (pt) | 2005-12-20 |
| RU2291862C2 (ru) | 2007-01-20 |
| IL169479A0 (en) | 2007-07-04 |
| KR20050101177A (ko) | 2005-10-20 |
| HK1085204A1 (zh) | 2006-08-18 |
| US20070066827A1 (en) | 2007-03-22 |
| JP2006517202A (ja) | 2006-07-20 |
| MXPA05007565A (es) | 2005-09-21 |
| AU2004203983A1 (en) | 2004-07-29 |
| WO2004063164A1 (en) | 2004-07-29 |
| CL2004000041A1 (es) | 2005-04-22 |
| ZA200505103B (en) | 2006-11-29 |
| TW200420286A (en) | 2004-10-16 |
| CN1738803A (zh) | 2006-02-22 |
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Comment text: Divisional Application for International Patent Patent event code: PA01041R01D Patent event date: 20070807 |
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| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |