CN100363350C - 芳基稠合多环内酰胺的制备方法 - Google Patents

芳基稠合多环内酰胺的制备方法 Download PDF

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Publication number
CN100363350C
CN100363350C CNB2004800022895A CN200480002289A CN100363350C CN 100363350 C CN100363350 C CN 100363350C CN B2004800022895 A CNB2004800022895 A CN B2004800022895A CN 200480002289 A CN200480002289 A CN 200480002289A CN 100363350 C CN100363350 C CN 100363350C
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CN
China
Prior art keywords
formula
compound
acid
dodeca
tricyclo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB2004800022895A
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English (en)
Chinese (zh)
Other versions
CN1738803A (zh
Inventor
R·E·小汉菲尔德
T·J·N·沃森
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Products Inc
Original Assignee
Pfizer Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc filed Critical Pfizer Products Inc
Publication of CN1738803A publication Critical patent/CN1738803A/zh
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Publication of CN100363350C publication Critical patent/CN100363350C/zh
Anticipated expiration legal-status Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CNB2004800022895A 2003-01-15 2004-01-08 芳基稠合多环内酰胺的制备方法 Expired - Fee Related CN100363350C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US44026603P 2003-01-15 2003-01-15
US60/440,266 2003-01-15

Publications (2)

Publication Number Publication Date
CN1738803A CN1738803A (zh) 2006-02-22
CN100363350C true CN100363350C (zh) 2008-01-23

Family

ID=32713537

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB2004800022895A Expired - Fee Related CN100363350C (zh) 2003-01-15 2004-01-08 芳基稠合多环内酰胺的制备方法

Country Status (18)

Country Link
US (1) US20070066827A1 (enExample)
EP (1) EP1587794A1 (enExample)
JP (1) JP2006517202A (enExample)
KR (2) KR20050101177A (enExample)
CN (1) CN100363350C (enExample)
AR (1) AR042855A1 (enExample)
AU (1) AU2004203983A1 (enExample)
BR (1) BRPI0406670A (enExample)
CA (1) CA2513293A1 (enExample)
CL (1) CL2004000041A1 (enExample)
IL (1) IL169479A0 (enExample)
MX (1) MXPA05007565A (enExample)
PL (1) PL379373A1 (enExample)
RS (1) RS20050513A (enExample)
RU (1) RU2291862C2 (enExample)
TW (1) TW200420286A (enExample)
WO (1) WO2004063164A1 (enExample)
ZA (1) ZA200505103B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2284319C2 (ru) 2002-11-25 2006-09-27 Пфайзер Продактс Инк. Усовершенствованный способ получения 1,3-замещенных инденов
RU2372323C1 (ru) * 2008-04-15 2009-11-10 Открытое акционерное общество Научно-производственное предприятие НИИПАВ (ОАО НПП НИИПАВ) Способ получения высокомолекулярных аминов
US8039620B2 (en) * 2008-05-22 2011-10-18 Teva Pharmaceutical Industries Ltd. Varenicline tosylate, an intermediate in the preparation process of varenicline L-tartrate
US20090318695A1 (en) * 2008-06-19 2009-12-24 Vinod Kumar Kansal Processes for the preparation of varenicline and intermediates thereof
US8178537B2 (en) * 2009-06-22 2012-05-15 Teva Pharmaceutical Industries Ltd. Solid state forms of varenicline salts and processes for preparation thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ271765A (en) * 1993-08-05 1996-11-26 Syntex Inc Bridged [1,3]indolo macrocyclic lactam compounds and pharmaceutical compositions
ATE386024T1 (de) * 1997-12-31 2008-03-15 Pfizer Prod Inc Arylkondensierte azapolycyclische derivate
US6605610B1 (en) * 1997-12-31 2003-08-12 Pfizer Inc Aryl fused azapolycyclic compounds
DK1383733T3 (da) * 2001-04-20 2008-06-09 Pfizer Prod Inc Fremgangsmåde til fremstilling af 1,3-substituerede indener og aryl-sammenföjede azapolycykliske forbindelser

Also Published As

Publication number Publication date
CA2513293A1 (en) 2004-07-29
MXPA05007565A (es) 2005-09-21
ZA200505103B (en) 2006-11-29
CL2004000041A1 (es) 2005-04-22
JP2006517202A (ja) 2006-07-20
CN1738803A (zh) 2006-02-22
IL169479A0 (en) 2007-07-04
RU2005122406A (ru) 2006-01-27
WO2004063164A8 (en) 2005-05-26
AR042855A1 (es) 2005-07-06
AU2004203983A1 (en) 2004-07-29
WO2004063164A1 (en) 2004-07-29
HK1085204A1 (zh) 2006-08-18
KR20070087258A (ko) 2007-08-27
KR20050101177A (ko) 2005-10-20
EP1587794A1 (en) 2005-10-26
PL379373A1 (pl) 2006-08-21
TW200420286A (en) 2004-10-16
RU2291862C2 (ru) 2007-01-20
RS20050513A (sr) 2007-11-15
US20070066827A1 (en) 2007-03-22
BRPI0406670A (pt) 2005-12-20

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