JP2006514931A5 - - Google Patents

Info

Publication number

JP2006514931A5

JP2006514931A5 JP2004554400A JP2004554400A JP2006514931A5 JP 2006514931 A5 JP2006514931 A5 JP 2006514931A5 JP 2004554400 A JP2004554400 A JP 2004554400A JP 2004554400 A JP2004554400 A JP 2004554400A JP 2006514931 A5 JP2006514931 A5 JP 2006514931A5

Authority

JP

Japan

Prior art keywords

pharmaceutical composition

formula

compounds

plant extract

compound

Prior art date

2003-11-20

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 150000001875 compounds Chemical class 0.000 claims 10
• 239000008194 pharmaceutical composition Substances 0.000 claims 7
• 239000000419 plant extract Substances 0.000 claims 6
• 241000209761 Avena Species 0.000 claims 2
• 235000005781 Avena Nutrition 0.000 claims 2
• 241000219322 Dianthus Species 0.000 claims 2
• 241000196324 Embryophyta Species 0.000 claims 2
• NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 claims 2
• 208000003251 Pruritus Diseases 0.000 claims 2
• 241000219289 Silene Species 0.000 claims 2
• 229910052918 calcium silicate Inorganic materials 0.000 claims 2
• 239000000284 extract Substances 0.000 claims 2
• 239000000203 mixture Substances 0.000 claims 2
• QDZOEBFLNHCSSF-PFFBOGFISA-N (2S)-2-[[(2R)-2-[[(2S)-1-[(2S)-6-amino-2-[[(2S)-1-[(2R)-2-amino-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-N-[(2R)-1-[[(2S)-1-[[(2R)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]pentanediamide Chemical compound C([C@@H](C(=O)N[C@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](N)CCCNC(N)=N)C1=CC=CC=C1 QDZOEBFLNHCSSF-PFFBOGFISA-N 0.000 claims 1
• 235000009051 Ambrosia paniculata var. peruviana Nutrition 0.000 claims 1
• 235000003097 Artemisia absinthium Nutrition 0.000 claims 1
• 240000001851 Artemisia dracunculus Species 0.000 claims 1
• 235000017731 Artemisia dracunculus ssp. dracunculus Nutrition 0.000 claims 1
• 235000003261 Artemisia vulgaris Nutrition 0.000 claims 1
• 206010012434 Dermatitis allergic Diseases 0.000 claims 1
• 102100024304 Protachykinin-1 Human genes 0.000 claims 1
• 101800003906 Substance P Proteins 0.000 claims 1
• 125000000217 alkyl group Chemical group 0.000 claims 1
• 239000001138 artemisia absinthium Substances 0.000 claims 1
• 239000002537 cosmetic Substances 0.000 claims 1
• 201000010099 disease Diseases 0.000 claims 1
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
• 229960001340 histamine Drugs 0.000 claims 1
• 210000003630 histaminocyte Anatomy 0.000 claims 1
• 210000003491 skin Anatomy 0.000 claims 1
• 239000000126 substance Substances 0.000 claims 1
• KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 1
• 208000024891 symptom Diseases 0.000 claims 1