JP2006504761A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2006504761A5 JP2006504761A5 JP2004547576A JP2004547576A JP2006504761A5 JP 2006504761 A5 JP2006504761 A5 JP 2006504761A5 JP 2004547576 A JP2004547576 A JP 2004547576A JP 2004547576 A JP2004547576 A JP 2004547576A JP 2006504761 A5 JP2006504761 A5 JP 2006504761A5
- Authority
- JP
- Japan
- Prior art keywords
- chloro
- alkyl
- phenyl
- acetamide
- phenoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 B*NC(N(*)***NC)=O Chemical compound B*NC(N(*)***NC)=O 0.000 description 7
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10250743A DE10250743A1 (de) | 2002-10-31 | 2002-10-31 | Neue Amid-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| PCT/EP2003/011933 WO2004039764A1 (de) | 2002-10-31 | 2003-10-28 | Neue amid-verbindungen mit mch-antagonistischer wirkung und diese verbindungen enthaltende arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2006504761A JP2006504761A (ja) | 2006-02-09 |
| JP2006504761A5 true JP2006504761A5 (https=) | 2009-10-08 |
Family
ID=32115015
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004547576A Pending JP2006504761A (ja) | 2002-10-31 | 2003-10-28 | Ｍｃｈ拮抗活性を有する新規アミド化合物及びこれらの化合物を含む薬物 |
Country Status (24)
| Country | Link |
|---|---|
| EP (1) | EP1558567B1 (https=) |
| JP (1) | JP2006504761A (https=) |
| KR (1) | KR20050065654A (https=) |
| CN (1) | CN1708476A (https=) |
| AR (1) | AR041735A1 (https=) |
| AT (1) | ATE434601T1 (https=) |
| AU (1) | AU2003285306A1 (https=) |
| BR (1) | BR0315797A (https=) |
| CA (1) | CA2504207C (https=) |
| CO (1) | CO5570698A2 (https=) |
| DE (2) | DE10250743A1 (https=) |
| EA (1) | EA009040B1 (https=) |
| EC (1) | ECSP055765A (https=) |
| ES (1) | ES2327329T3 (https=) |
| HR (1) | HRP20050383A2 (https=) |
| MX (1) | MXPA05002865A (https=) |
| NO (1) | NO20050745L (https=) |
| PE (1) | PE20040785A1 (https=) |
| PL (1) | PL376256A1 (https=) |
| RS (1) | RS20050330A (https=) |
| TW (1) | TW200412936A (https=) |
| UY (1) | UY28051A1 (https=) |
| WO (1) | WO2004039764A1 (https=) |
| ZA (1) | ZA200501164B (https=) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7592373B2 (en) | 2003-12-23 | 2009-09-22 | Boehringer Ingelheim International Gmbh | Amide compounds with MCH antagonistic activity and medicaments comprising these compounds |
| FR2866880A1 (fr) * | 2004-02-27 | 2005-09-02 | Oreal | Para-phenylenediamine secondaire n-alkylaminee ortho-et/ou meta-substituee, composition de teinture des fibres keratiniques contenant une telle para-phenylenediamine, procedes mettant en oeuvre cette composition et utilisations |
| US7605176B2 (en) | 2004-03-06 | 2009-10-20 | Boehringer Ingelheim International Gmbh | β-ketoamide compounds with MCH antagonistic activity |
| JP2006076990A (ja) * | 2004-03-12 | 2006-03-23 | Bayer Cropscience Ag | 殺虫性ベンゼンジカルボキサミド類 |
| DE102004017934A1 (de) | 2004-04-14 | 2005-11-03 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Alkin-Verbindungen mit MCH-antagonistischer Wirkung und diese Verbindungen enthaltende Arzneimittel |
| US7524862B2 (en) | 2004-04-14 | 2009-04-28 | Boehringer Ingelheim International Gmbh | Alkyne compounds with MCH antagonistic activity and medicaments comprising these compounds |
| KR20090047542A (ko) | 2006-08-25 | 2009-05-12 | 베링거 인겔하임 인터내셔날 게엠베하 | Ｍｃｈ 길항 활성을 갖는 신규한 피리돈 유도체 및 당해 화합물을 포함하는 의약 |
| WO2008069611A1 (en) * | 2006-12-08 | 2008-06-12 | Korea Research Institute Of Chemical Technology | N-phenylamide derivative, process for the preparation thereof, and composition for preventing or treating ischemic diseases comprising same |
| WO2008071646A1 (en) | 2006-12-11 | 2008-06-19 | Boehringer Ingelheim International Gmbh | New pyridazine derivatives with mch antagonistic activity and medicaments comprising these compounds |
| WO2010015680A1 (en) * | 2008-08-07 | 2010-02-11 | Bayer Cropscience Sa | Fungicide oxyalkylamide derivatives |
| EP2348857B1 (en) | 2008-10-22 | 2016-02-24 | Merck Sharp & Dohme Corp. | Novel cyclic benzimidazole derivatives useful anti-diabetic agents |
| US8329914B2 (en) | 2008-10-31 | 2012-12-11 | Merck Sharp & Dohme Corp | Cyclic benzimidazole derivatives useful as anti-diabetic agents |
| US9452980B2 (en) * | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
| JP2013520502A (ja) | 2010-02-25 | 2013-06-06 | メルク・シャープ・エンド・ドーム・コーポレイション | 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体 |
| US9079880B2 (en) * | 2010-07-07 | 2015-07-14 | Boehringer Ingelheim International Gmbh | Rho kinase inhibitors |
| WO2012008549A1 (ja) * | 2010-07-15 | 2012-01-19 | 武田薬品工業株式会社 | 複素環化合物 |
| SG192941A1 (en) | 2011-02-25 | 2013-09-30 | Merck Sharp & Dohme | Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents |
| EP4234545A3 (en) | 2011-07-29 | 2023-09-06 | Karyopharm Therapeutics Inc. | Hydrazide containing nuclear transport modulators and uses thereof |
| JP6006794B2 (ja) * | 2011-07-29 | 2016-10-12 | カリオファーム セラピューティクス，インコーポレイテッド | 核内輸送調節因子およびその使用 |
| JP2015512913A (ja) | 2012-03-28 | 2015-04-30 | ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ | グルコセレブロシダーゼ活性剤として有用なサリチル酸誘導体 |
| WO2013170068A2 (en) | 2012-05-09 | 2013-11-14 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| RU2015106909A (ru) | 2012-08-02 | 2016-09-27 | Мерк Шарп И Доум Корп. | Антидиабетические трициклические соединения |
| KR20150118158A (ko) | 2013-02-22 | 2015-10-21 | 머크 샤프 앤드 돔 코포레이션 | 항당뇨병 비시클릭 화합물 |
| WO2014139388A1 (en) | 2013-03-14 | 2014-09-18 | Merck Sharp & Dohme Corp. | Novel indole derivatives useful as anti-diabetic agents |
| EP2968278B8 (en) | 2013-03-15 | 2019-05-22 | Karyopharm Therapeutics Inc. | Methods of promoting wound healing using crm1 inhibitors |
| ME03421B (me) | 2013-06-21 | 2020-01-20 | Karyopharm Therapeutics Inc | 1,2,4-triazoli kao modulatori nuklearnog transporta i njihova upotreba |
| EP3013796B9 (en) | 2013-06-27 | 2020-07-01 | LG Chem, Ltd. | Biaryl derivatives as gpr120 agonists |
| WO2015051496A1 (en) | 2013-10-08 | 2015-04-16 | Merck Sharp & Dohme Corp. | Antidiabetic tricyclic compounds |
| KR102608259B1 (ko) | 2014-08-15 | 2023-11-29 | 카리오팜 쎄라퓨틱스, 인코포레이티드 | 셀리넥소의 다형태 |
| CN105439914B (zh) * | 2014-09-17 | 2017-07-11 | 复旦大学 | 4‑氨酰基苯氧乙酰胺类化合物及其药物用途 |
| BR112017013465A2 (pt) * | 2014-12-24 | 2018-03-06 | Lg Chem, Ltd | derivado de biarila, e, composição farmacêutica. |
| JP6533997B2 (ja) * | 2014-12-26 | 2019-06-26 | 株式会社ヤクルト本社 | Ｚｎｆ１４３阻害活性を有する化合物およびその利用 |
| US10526295B2 (en) | 2015-12-31 | 2020-01-07 | Karyopharm Therapeutics Inc. | Nuclear transport modulators and uses thereof |
| EP3397634A1 (en) | 2015-12-31 | 2018-11-07 | Karyopharm Therapeutics, Inc. | Nuclear transport modulators and uses thereof |
| CN108713019B (zh) | 2016-03-17 | 2021-06-15 | 豪夫迈·罗氏有限公司 | 具有作为taar的激动剂的活性的5-乙基-4-甲基-吡唑-3-甲酰胺衍生物 |
| US11602530B2 (en) | 2016-11-28 | 2023-03-14 | Biogen Ma Inc. | CRM1 inhibitors for treating epilepsy |
| US11072602B2 (en) | 2016-12-06 | 2021-07-27 | Merck Sharp & Dohme Corp. | Antidiabetic heterocyclic compounds |
| EP3558298B1 (en) | 2016-12-20 | 2026-03-11 | Merck Sharp & Dohme LLC | Antidiabetic spirochroman compounds |
| BR112022000185A2 (pt) | 2019-07-10 | 2022-02-22 | Bayer Ag | Método de preparação de 2-(fenilimino)-1,3-tiazolidin-4-onas |
| BR112023015210A2 (pt) | 2021-01-29 | 2023-11-07 | Cedilla Therapeutics Inc | Inibidores de cdk2 e métodos de uso dos mesmos |
| CA3225439A1 (en) | 2021-06-26 | 2022-12-29 | Cedilla Therapeutics, Inc. | Cdk2 inhibitors and methods of using the same |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2338804A1 (en) * | 1998-07-28 | 2000-02-10 | Smithkline Beecham Corporation | Propenamides as ccr5 modulators |
| EP1218336A2 (en) * | 1999-09-20 | 2002-07-03 | Takeda Chemical Industries, Ltd. | Melanin concentrating hormone antagonist |
| EP1299362A4 (en) * | 2000-07-05 | 2004-11-03 | Synaptic Pharma Corp | SELECTIVE RECEPTOR ANTAGONISTS OF MELANINE CONCENTRATING HORMON-1 (MCH1) AND THEIR USE |
| US20030022891A1 (en) * | 2000-12-01 | 2003-01-30 | Anandan Palani | MCH antagonists and their use in the treatment of obesity |
| CN100548291C (zh) * | 2001-10-25 | 2009-10-14 | 先灵公司 | 用于治疗肥胖的mch拮抗剂 |
-
2002
- 2002-10-31 DE DE10250743A patent/DE10250743A1/de not_active Withdrawn
-
2003
- 2003-10-28 AU AU2003285306A patent/AU2003285306A1/en not_active Abandoned
- 2003-10-28 EP EP03778292A patent/EP1558567B1/de not_active Expired - Lifetime
- 2003-10-28 CN CNA2003801022366A patent/CN1708476A/zh active Pending
- 2003-10-28 WO PCT/EP2003/011933 patent/WO2004039764A1/de not_active Ceased
- 2003-10-28 BR BR0315797-0A patent/BR0315797A/pt not_active IP Right Cessation
- 2003-10-28 RS YUP-2005/0330A patent/RS20050330A/sr unknown
- 2003-10-28 KR KR1020057007663A patent/KR20050065654A/ko not_active Withdrawn
- 2003-10-28 ES ES03778292T patent/ES2327329T3/es not_active Expired - Lifetime
- 2003-10-28 EA EA200500596A patent/EA009040B1/ru not_active IP Right Cessation
- 2003-10-28 DE DE50311640T patent/DE50311640D1/de not_active Expired - Lifetime
- 2003-10-28 CA CA2504207A patent/CA2504207C/en not_active Expired - Lifetime
- 2003-10-28 MX MXPA05002865A patent/MXPA05002865A/es not_active Application Discontinuation
- 2003-10-28 AT AT03778292T patent/ATE434601T1/de active
- 2003-10-28 JP JP2004547576A patent/JP2006504761A/ja active Pending
- 2003-10-28 PL PL03376256A patent/PL376256A1/xx not_active Application Discontinuation
- 2003-10-28 HR HR20050383A patent/HRP20050383A2/xx not_active Application Discontinuation
- 2003-10-29 UY UY28051A patent/UY28051A1/es not_active Application Discontinuation
- 2003-10-29 PE PE2003001094A patent/PE20040785A1/es not_active Application Discontinuation
- 2003-10-30 TW TW092130313A patent/TW200412936A/zh unknown
- 2003-10-31 AR ARP030103995A patent/AR041735A1/es unknown
-
2005
- 2005-02-09 ZA ZA200501164A patent/ZA200501164B/en unknown
- 2005-02-11 NO NO20050745A patent/NO20050745L/no not_active Application Discontinuation
- 2005-04-27 EC EC2005005765A patent/ECSP055765A/es unknown
- 2005-05-26 CO CO05051560A patent/CO5570698A2/es not_active Application Discontinuation
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2006504761A5 (https=) | ||
| RU2201927C2 (ru) | Амидиновые соединения и фармацевтическая композиция, обладающая фактор ха ингибирующим действием | |
| CA2504207A1 (en) | New amide compounds having mch-antagonistic activity and medicaments comprising these compounds | |
| US6939891B2 (en) | Heterocyclic ureas, their preparation and their use as vanilloid receptor antagonists | |
| JP2007528883A5 (https=) | ||
| BG64848B1 (bg) | Циклични аминопроизводни и използването им като лекарства | |
| RU2005117783A (ru) | 1, 5-диарилпиррол-3-карбоксамидные производные и их применение в качестве модуляторов каннабиноидных рецепторов | |
| JP2004508304A5 (https=) | ||
| RU2003136097A (ru) | Производные фенилпиридинкарбонилпиперазина | |
| JP2005513123A5 (https=) | ||
| WO2006112685A1 (en) | Neurotherapeutic azole compounds | |
| JP2010521515A5 (https=) | ||
| RU97118779A (ru) | Производные арилглицинамидов, способ их получения и фармацевтические композиции, содержащие эти соединения | |
| CA2527159A1 (en) | 3-aminomethyl-pyrrolidines as n-type calcium channel blockers | |
| JP2005523310A5 (https=) | ||
| CA2407149A1 (en) | Melanin-concentrating hormone antagonist | |
| HUP0302966A2 (hu) | Karboxamid-vegyületek és alkalmazásuk humán 11CBY receptor antagonistákként, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények | |
| MEP22008A (en) | Derivatives of n-[heteroaryl(piperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics | |
| EP0661266A1 (en) | Substituted cyclic amine compounds as 5HT2 antagonists | |
| RU2005111974A (ru) | Производные пирролидона в качестве ингибиторов маов | |
| JP2010504930A5 (https=) | ||
| JP2000504677A (ja) | ５ｈｔ７レセプター・アンタゴニスト用のスルホンアミド誘導体 | |
| WO2004011430A1 (ja) | ナトリウムチャネル阻害剤 | |
| RU2011127451A (ru) | ПРОИЗВОДНЫЕ ТИЕНО[3,2-c]ПИРИДИНА В КАЧЕСТВЕ ИНГИБИТОРОВ КИНАЗ ДЛЯ ПРИМЕНЕНИЯ В ЛЕЧЕНИИ РАКА | |
| JPH10279578A5 (https=) |