JP2006501240A5 - - Google Patents
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- Publication number
- JP2006501240A5 JP2006501240A5 JP2004531017A JP2004531017A JP2006501240A5 JP 2006501240 A5 JP2006501240 A5 JP 2006501240A5 JP 2004531017 A JP2004531017 A JP 2004531017A JP 2004531017 A JP2004531017 A JP 2004531017A JP 2006501240 A5 JP2006501240 A5 JP 2006501240A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- injection
- site
- unacceptable
- administering
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000009472 formulation Methods 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 229940090044 Injection Drugs 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 229940025916 aripiprazole Injection Drugs 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 201000000980 schizophrenia Diseases 0.000 claims 1
- 230000000638 stimulation Effects 0.000 claims 1
Claims (3)
- 治療が必要な患者に対して、注射部位に許容できない刺激を与えることなくアリピプラゾールの注射剤を投与するための、請求項１７の製剤。
- 筋肉内投与するための、請求項２２の製剤。
- 統合失調症を治療するため、注射部位に許容できない刺激を与えることなく投与される、請求項５の製剤。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US40471302P | 2002-08-20 | 2002-08-20 | |
| US60/404,713 | 2002-08-20 | ||
| PCT/US2003/025573 WO2004017897A2 (en) | 2002-08-20 | 2003-08-14 | Aripiprazole complex formulation and method |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006501240A JP2006501240A (ja) | 2006-01-12 |
| JP2006501240A5 true JP2006501240A5 (ja) | 2006-06-08 |
| JP4729306B2 JP4729306B2 (ja) | 2011-07-20 |
Family
ID=31946748
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004531017A Expired - Fee Related JP4729306B2 (ja) | 2002-08-20 | 2003-08-14 | アリピプラゾール錯体の製剤と方法 |
Country Status (32)
| Country | Link |
|---|---|
| US (8) | US7115587B2 (ja) |
| EP (1) | EP1542668B1 (ja) |
| JP (1) | JP4729306B2 (ja) |
| KR (1) | KR101043866B1 (ja) |
| CN (1) | CN100335047C (ja) |
| AR (2) | AR040887A1 (ja) |
| AT (1) | ATE428423T1 (ja) |
| AU (1) | AU2003269965B2 (ja) |
| BR (1) | BR0313602A (ja) |
| CA (1) | CA2495864C (ja) |
| CY (1) | CY1110331T1 (ja) |
| DE (1) | DE60327225D1 (ja) |
| DK (1) | DK1542668T3 (ja) |
| ES (1) | ES2322953T3 (ja) |
| GE (1) | GEP20063996B (ja) |
| HR (1) | HRP20050149B1 (ja) |
| IL (1) | IL166623A (ja) |
| IS (1) | IS2878B (ja) |
| MX (1) | MXPA05001865A (ja) |
| MY (1) | MY140793A (ja) |
| NO (1) | NO333458B1 (ja) |
| NZ (1) | NZ537995A (ja) |
| PE (1) | PE20040895A1 (ja) |
| PL (1) | PL212428B1 (ja) |
| PT (1) | PT1542668E (ja) |
| RS (1) | RS51903B (ja) |
| RU (1) | RU2342931C2 (ja) |
| SI (1) | SI1542668T1 (ja) |
| TW (1) | TWI307626B (ja) |
| UA (1) | UA79984C2 (ja) |
| WO (1) | WO2004017897A2 (ja) |
| ZA (1) | ZA200501064B (ja) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040170705A1 (en) * | 2001-03-08 | 2004-09-02 | Dusan Miljkovic | Compositions and methods for non-insulin glucose uptake |
| US7115587B2 (en) * | 2002-08-20 | 2006-10-03 | Bristol-Myers Squibb Company | Aripiprazole complex formulation and method |
| PT1675573E (pt) * | 2003-10-23 | 2008-12-30 | Otsuka Pharma Co Ltd | Formulação de iripiprazole injectável estéril de libertação controlada e um processo para a sua preparação |
| US7714129B2 (en) | 2003-12-16 | 2010-05-11 | Teva Pharmaceutical Industries Ltd. | Methods of preparing anhydrous aripiprazole form II |
| CA2550726A1 (en) * | 2003-12-16 | 2005-06-30 | Teva Pharmaceutical Industries Ltd. | Methods of preparing aripiprazole crystalline forms |
| UA89513C2 (uk) * | 2004-12-03 | 2010-02-10 | Элан Фарма Интернешнл Лтд. | Стабільна композиція з наночастинок ралоксифену гідрохлориду |
| US20090252807A1 (en) * | 2005-04-13 | 2009-10-08 | Elan Pharma International Limited | Nanoparticulate and Controlled Release Compositions Comprising Prostaglandin Derivatives |
| DE602006012671D1 (de) * | 2005-06-03 | 2010-04-15 | Elan Pharma Int Ltd | Nanoteilchenförmige imatinib-mesylat-formulierungen |
| CA2611917A1 (en) * | 2005-06-13 | 2006-12-21 | Takeda Pharmaceutical Company Limited | Injection |
| US20100204178A1 (en) | 2006-10-02 | 2010-08-12 | James Cloyd | Novel parenteral carbamazepine formulation |
| US8022054B2 (en) | 2005-11-28 | 2011-09-20 | Marinus Pharmaceuticals | Liquid ganaxolone formulations and methods for the making and use thereof |
| GB0618879D0 (en) | 2006-09-26 | 2006-11-01 | Zysis Ltd | Pharmaceutical compositions |
| CN101322709B (zh) * | 2007-06-12 | 2011-03-02 | 成都康弘药业集团股份有限公司 | 一种含有阿立哌唑的药物组合物及其制备方法 |
| RU2483711C2 (ru) * | 2007-07-31 | 2013-06-10 | Оцука Фармасьютикал Ко., Лтд. | Способы получения суспензии арипипразола и лиофилизированного состава |
| WO2009048947A1 (en) * | 2007-10-09 | 2009-04-16 | Board Of Regents, The University Of Texas System | Methods of treatment of opioid tolerance, physical dependence, pain, and addiction with inhibitors of certain growth factor receptors |
| KR20110007095A (ko) * | 2008-03-21 | 2011-01-21 | 엘란 파마 인터내셔널 리미티드 | 이마티니브의 부위-특이적 전달을 위한 조성물 및 사용방법 |
| US7635773B2 (en) | 2008-04-28 | 2009-12-22 | Cydex Pharmaceuticals, Inc. | Sulfoalkyl ether cyclodextrin compositions |
| LT2445502T (lt) * | 2009-06-25 | 2017-09-25 | Alkermes Pharma Ireland Limited | Heterocikliniai junginiai, skirti neurologinių ir fiziologinių susirgimų gydymui |
| US8686009B2 (en) * | 2009-06-25 | 2014-04-01 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds |
| WO2011023796A1 (en) | 2009-08-31 | 2011-03-03 | Abbott Healthcare Products B.V. | Bifeprunox for treating addiction |
| KR101125210B1 (ko) * | 2009-09-11 | 2012-03-19 | 주식회사 대웅제약 | 아리피프라졸-벤토나이트-ａｅａ 혼성체, 이를 함유하는 약학 조성물 및 그 제조방법 |
| US20110140304A1 (en) * | 2009-12-10 | 2011-06-16 | Molecular Imprints, Inc. | Imprint lithography template |
| AU2011270701B2 (en) | 2010-06-24 | 2015-05-14 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
| US8383663B2 (en) * | 2010-07-19 | 2013-02-26 | Supratek Pharma Inc. | Bendamustine anionic-catioinic cyclopolysaccharide compositions |
| CA2830511C (en) | 2011-03-18 | 2021-09-14 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising aripiprazole lauroxil and sorbitan laurate |
| NZ722096A (en) | 2011-12-15 | 2016-11-25 | Alkermes Pharma Ireland Ltd | Prodrugs of secondary amine compounds |
| TW201332572A (zh) * | 2011-12-28 | 2013-08-16 | Otsuka Pharma Co Ltd | 具有經取代的β－環糊精之藥物製劑 |
| JP6508944B2 (ja) | 2012-02-15 | 2019-05-08 | サイデックス・ファーマシューティカルズ・インコーポレイテッド | シクロデキストリン誘導体のための製造方法 |
| US9999670B2 (en) | 2012-03-19 | 2018-06-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
| US9993556B2 (en) | 2012-03-19 | 2018-06-12 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising fatty glycerol esters |
| CA2867121C (en) | 2012-03-19 | 2021-05-25 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising fatty acid esters |
| JOP20200109A1 (ar) | 2012-04-23 | 2017-06-16 | Otsuka Pharma Co Ltd | مستحضر قابل للحقن |
| KR101571670B1 (ko) * | 2012-08-08 | 2015-11-25 | 주식회사 씨엠지제약 | 아리피프라졸을 포함하는 경구용 속용 필름 제제 |
| EP3718536A1 (en) | 2012-09-19 | 2020-10-07 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions having improved storage stability |
| JP6440625B2 (ja) | 2012-11-14 | 2018-12-19 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 精神分裂病を処置するための方法および組成物 |
| GR1008186B (el) | 2013-04-22 | 2014-05-08 | "Φαρματεν Α.Β.Ε.Ε.", | Φαρμακευτικο σκευασμα περιεχον ενα ατυπο αντιψυχωσικο παραγοντα και μεθοδος για την παρασκευη αυτου |
| JP6203682B2 (ja) * | 2013-07-10 | 2017-09-27 | 共和薬品工業株式会社 | アリピプラゾール含有水性液剤 |
| US10525057B2 (en) | 2013-09-24 | 2020-01-07 | Otsuka Pharmaceutical Co., Ltd. | Method of providing aripiprazole to patients having impaired CYP2D6 or CYP3A4 enzyme function |
| US20150086408A1 (en) * | 2013-09-26 | 2015-03-26 | General Electric Company | Method of manufacturing a component and thermal management process |
| PL3639828T3 (pl) | 2013-12-24 | 2022-05-02 | Virginia Commonwealth University | Zastosowanie utlenowanych siarczanów cholesterolu (ocs) w leczeniu ostrej niewydolności wątroby |
| GR1008442B (el) | 2014-01-16 | 2015-03-05 | "Φαρματεν Α.Β.Ε.Ε.", | Φαρμακευτικο σκευασμα περιεχον αριπιπραζολη ή αλας αυτης |
| MA39495A (fr) | 2014-03-20 | 2015-09-24 | Alkermes Pharma Ireland Ltd | Formulations d'aripiprazole présentant des vitesses d'injection plus élevées |
| CN105078910B (zh) * | 2015-09-22 | 2018-05-22 | 成都欣捷高新技术开发有限公司 | 一种含有依匹哌唑的冻干口服制剂及其制备方法 |
| KR20180082457A (ko) | 2015-10-16 | 2018-07-18 | 마리누스 파마슈티컬스 인코포레이티드 | 나노입자들을 포함하는 주사용 뉴로스테로이드 제제들 |
| CN105616344A (zh) * | 2016-01-06 | 2016-06-01 | 万全万特制药江苏有限公司 | 阿立哌唑注射液及其制备方法 |
| EP4101861A1 (en) * | 2016-08-02 | 2022-12-14 | Virginia Commonwealth University | Compositions comprising 5-cholesten-3, 25-diol, 3-sulfate (25hc3s) or pharmaceutically acceptable salt thereof and at least one cyclic oligosaccharide |
| WO2018031748A1 (en) | 2016-08-11 | 2018-02-15 | Ovid Therapeutics Inc. | Methods and compositions for treatment of epileptic disorders |
| US10391105B2 (en) | 2016-09-09 | 2019-08-27 | Marinus Pharmaceuticals Inc. | Methods of treating certain depressive disorders and delirium tremens |
| EP3541364A1 (en) | 2016-11-18 | 2019-09-25 | AiCuris Anti-infective Cures GmbH | Novel formulations of amidine substituted beta-lactam compounds on the basis of modified cyclodextrins and acidifying agents, their preparation and use as antimicrobial pharmaceutical compositions |
| US11033506B2 (en) | 2017-11-21 | 2021-06-15 | Sekisui Chemical Co., Ltd. | External skin preparation comprising a core-shell structure |
| EP3761983A1 (en) | 2018-03-05 | 2021-01-13 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
| WO2020118142A1 (en) | 2018-12-07 | 2020-06-11 | Marinus Pharmaceuticals, Inc. | Ganaxolone for use in prophylaxis and treatment of pospartum depression |
| MX2022001553A (es) | 2019-08-05 | 2022-04-18 | Marinus Pharmaceuticals Inc | Ganaxolona para su uso en el tratamiento del estado epileptico. |
| WO2021113834A1 (en) | 2019-12-06 | 2021-06-10 | Marinus Pharmaceuticals, Inc. | Ganaxolone for use in treating tuberous sclerosis complex |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6407079B1 (en) | 1985-07-03 | 2002-06-18 | Janssen Pharmaceutica N.V. | Pharmaceutical compositions containing drugs which are instable or sparingly soluble in water and methods for their preparation |
| US5002935A (en) | 1987-12-30 | 1991-03-26 | University Of Florida | Improvements in redox systems for brain-targeted drug delivery |
| JP2608788B2 (ja) * | 1988-10-31 | 1997-05-14 | 大塚製薬 株式会社 | 精神分裂病治療剤 |
| US5006528A (en) | 1988-10-31 | 1991-04-09 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
| JP2893175B2 (ja) * | 1988-10-31 | 1999-05-17 | 大塚製薬株式会社 | カルボスチリル誘導体 |
| US5376645A (en) | 1990-01-23 | 1994-12-27 | University Of Kansas | Derivatives of cyclodextrins exhibiting enhanced aqueous solubility and the use thereof |
| KR0166088B1 (ko) | 1990-01-23 | 1999-01-15 | . | 수용해도가 증가된 시클로덱스트린 유도체 및 이의 용도 |
| IT1263831B (it) | 1993-01-29 | 1996-09-04 | Paolo Chiesi | Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina |
| JPH07165616A (ja) * | 1993-12-09 | 1995-06-27 | Hisamitsu Pharmaceut Co Inc | シクロデキストリンの複合組成物及び複合化法 |
| US5646131A (en) | 1994-02-22 | 1997-07-08 | The Arab Company For Drug Industries And Medical Applicances (Acdima) | Method for solubilizing drugs using cyclodextrins and carboxylic acids |
| IT1269578B (it) | 1994-04-22 | 1997-04-08 | Chiesi Farma Spa | Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo acido, una ciclodestrina e una base. |
| UA57734C2 (uk) | 1996-05-07 | 2003-07-15 | Пфайзер Інк. | Комплекси включення арилгетероциклічних солей |
| JP4012994B2 (ja) | 1996-05-08 | 2007-11-28 | 大塚製薬株式会社 | 抗不安薬 |
| JPH10194996A (ja) | 1996-12-25 | 1998-07-28 | Janssen Pharmaceut Nv | アシル化シクロデキストリン含有製薬組成物 |
| GB9713149D0 (en) | 1997-06-21 | 1997-08-27 | Pfizer Ltd | Pharmaceutical formulations |
| GB9915231D0 (en) | 1999-06-29 | 1999-09-01 | Pfizer Ltd | Pharmaceutical complex |
| CA2311734C (en) | 2000-04-12 | 2011-03-08 | Bristol-Myers Squibb Company | Flash-melt oral dosage formulation |
| MY129350A (en) * | 2001-04-25 | 2007-03-30 | Bristol Myers Squibb Co | Aripiprazole oral solution |
| AR033485A1 (es) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | Sustancia medicinal de aripiprazol de baja higroscopicidad y proceso para la preparacion de la misma |
| SE0200301D0 (sv) * | 2002-02-01 | 2002-02-01 | Axon Biochemicals Bv | Thio-carbostyril derivative |
| US7115587B2 (en) * | 2002-08-20 | 2006-10-03 | Bristol-Myers Squibb Company | Aripiprazole complex formulation and method |
| KR20050071611A (ko) | 2002-10-25 | 2005-07-07 | 화이자 프로덕츠 인코포레이티드 | 현탁액 형태의 아릴헤테로환 활성제의 저장 제형 |
-
2003
- 2003-08-14 US US10/642,366 patent/US7115587B2/en active Active
- 2003-08-14 DK DK03751859T patent/DK1542668T3/da active
- 2003-08-14 JP JP2004531017A patent/JP4729306B2/ja not_active Expired - Fee Related
- 2003-08-14 TW TW092122407A patent/TWI307626B/zh not_active IP Right Cessation
- 2003-08-14 PL PL374798A patent/PL212428B1/pl unknown
- 2003-08-14 MX MXPA05001865A patent/MXPA05001865A/es active IP Right Grant
- 2003-08-14 WO PCT/US2003/025573 patent/WO2004017897A2/en active Application Filing
- 2003-08-14 UA UAA200502492A patent/UA79984C2/uk unknown
- 2003-08-14 KR KR1020057002789A patent/KR101043866B1/ko active IP Right Grant
- 2003-08-14 AT AT03751859T patent/ATE428423T1/de active
- 2003-08-14 DE DE60327225T patent/DE60327225D1/de not_active Expired - Lifetime
- 2003-08-14 ES ES03751859T patent/ES2322953T3/es not_active Expired - Lifetime
- 2003-08-14 SI SI200331586T patent/SI1542668T1/sl unknown
- 2003-08-14 RU RU2005107471/15A patent/RU2342931C2/ru not_active IP Right Cessation
- 2003-08-14 CN CNB038195534A patent/CN100335047C/zh not_active Expired - Fee Related
- 2003-08-14 BR BR0313602-7A patent/BR0313602A/pt not_active Application Discontinuation
- 2003-08-14 AU AU2003269965A patent/AU2003269965B2/en not_active Ceased
- 2003-08-14 CA CA2495864A patent/CA2495864C/en not_active Expired - Fee Related
- 2003-08-14 GE GEAP8703A patent/GEP20063996B/en unknown
- 2003-08-14 RS YU20050118A patent/RS51903B/sr unknown
- 2003-08-14 PT PT03751859T patent/PT1542668E/pt unknown
- 2003-08-14 NZ NZ537995A patent/NZ537995A/en not_active IP Right Cessation
- 2003-08-14 EP EP03751859A patent/EP1542668B1/en not_active Expired - Lifetime
- 2003-08-15 MY MYPI20033103A patent/MY140793A/en unknown
- 2003-08-19 AR AR20030102990A patent/AR040887A1/es not_active Application Discontinuation
- 2003-08-20 PE PE2003000843A patent/PE20040895A1/es not_active Application Discontinuation
-
2005
- 2005-02-01 IL IL166623A patent/IL166623A/en active IP Right Grant
- 2005-02-04 ZA ZA200501064A patent/ZA200501064B/xx unknown
- 2005-02-08 NO NO20050661A patent/NO333458B1/no not_active IP Right Cessation
- 2005-02-16 HR HRP20050149AA patent/HRP20050149B1/hr not_active IP Right Cessation
- 2005-02-18 IS IS7701A patent/IS2878B/is unknown
-
2006
- 2006-06-14 US US11/452,782 patent/US7550445B2/en not_active Expired - Fee Related
-
2009
- 2009-04-02 US US12/417,067 patent/US20090186903A1/en not_active Abandoned
- 2009-07-07 CY CY20091100712T patent/CY1110331T1/el unknown
-
2011
- 2011-03-11 US US13/046,124 patent/US20110160224A1/en not_active Abandoned
- 2011-11-03 US US13/288,077 patent/US20120053145A1/en not_active Abandoned
-
2012
- 2012-10-22 US US13/656,785 patent/US20130045981A1/en not_active Abandoned
-
2013
- 2013-04-29 US US13/872,517 patent/US8999952B2/en not_active Expired - Fee Related
-
2015
- 2015-03-03 US US14/636,283 patent/US20150328335A1/en not_active Abandoned
- 2015-09-28 AR ARP150103114A patent/AR102101A2/es unknown
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