JP2006500372A - 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 - Google Patents

選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Download PDF

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JP2006500372A
JP2006500372A JP2004530197A JP2004530197A JP2006500372A JP 2006500372 A JP2006500372 A JP 2006500372A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2006500372 A JP2006500372 A JP 2006500372A
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JP2006500372A5 (enExample
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ウェインガーテン，ゴードン
ブラヴィ，ジアンパオロ
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Glaxo Group Ltd
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Glaxo Group Ltd
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Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
Priority claimed from GB0219305A external-priority patent/GB0219305D0/en
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
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  • Cardiology (AREA)
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JP2004530197A 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Pending JP2006500372A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
PCT/EP2003/009153 WO2004018452A1 (en) 2002-08-19 2003-08-15 Pyrimidine derivatives as selective cox-2 inhibitors

Publications (2)

Publication Number Publication Date
JP2006500372A true JP2006500372A (ja) 2006-01-05
JP2006500372A5 JP2006500372A5 (enExample) 2006-09-07

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Application Number Title Priority Date Filing Date
JP2004530197A Pending JP2006500372A (ja) 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体

Country Status (8)

Country Link
US (1) US7235560B2 (enExample)
EP (1) EP1546128B1 (enExample)
JP (1) JP2006500372A (enExample)
AT (1) ATE325115T1 (enExample)
AU (1) AU2003258630A1 (enExample)
DE (1) DE60305053T2 (enExample)
ES (1) ES2263058T3 (enExample)
WO (1) WO2004018452A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE325115T1 (de) 2002-08-19 2006-06-15 Glaxo Group Ltd Pyrimidinderivate als selektive cox-2-inhibitoren
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
DE14172396T1 (de) 2004-10-08 2015-01-08 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
ZA200802411B (en) * 2005-09-15 2009-09-30 Orchid Res Lab Ltd Novel pyrimidine carboxamides
WO2007042035A2 (en) * 2005-10-07 2007-04-19 Aditech Pharma Ab Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
CN109044985A (zh) 2009-01-09 2018-12-21 前进制药知识产权有限公司 包含溶蚀骨架中的一种或多种富马酸酯的药物制剂
US20130012491A1 (en) * 2010-03-17 2013-01-10 Glaxo Group Limited Pyrimidine derivatives for use as sphingosine 1-phosphate 1 (s1p1) receptor agonists
US10774064B2 (en) 2016-06-02 2020-09-15 Cadent Therapeutics, Inc. Potassium channel modulators
JP6997197B2 (ja) 2017-01-23 2022-01-17 カデント セラピューティクス，インコーポレーテッド カリウムチャネルモジュレーター
MX2021004647A (es) 2018-10-22 2021-08-16 Novartis Ag Formas cristalinas de moduladores de los canales de potasio.
US20220348590A1 (en) * 2019-09-13 2022-11-03 The Board Institute, Inc. Cyclooxygenase-2 inhibitors and uses thereof

Citations (6)

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