JP2006500372A - 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 - Google Patents

選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Download PDF

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JP2006500372A
JP2006500372A JP2004530197A JP2004530197A JP2006500372A JP 2006500372 A JP2006500372 A JP 2006500372A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2004530197 A JP2004530197 A JP 2004530197A JP 2006500372 A JP2006500372 A JP 2006500372A
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JP2006500372A5 (enExample
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ウェインガーテン，ゴードン
ブラヴィ，ジアンパオロ
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Glaxo Group Ltd
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Glaxo Group Ltd
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Priority claimed from GB0219304A external-priority patent/GB0219304D0/en
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
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  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
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  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Psychology (AREA)
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JP2004530197A 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体 Pending JP2006500372A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0219305A GB0219305D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
GB0219304A GB0219304D0 (en) 2002-08-19 2002-08-19 Pyrimidine derivatives
PCT/EP2003/009153 WO2004018452A1 (en) 2002-08-19 2003-08-15 Pyrimidine derivatives as selective cox-2 inhibitors

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Publication Number Publication Date
JP2006500372A true JP2006500372A (ja) 2006-01-05
JP2006500372A5 JP2006500372A5 (enExample) 2006-09-07

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JP2004530197A Pending JP2006500372A (ja) 2002-08-19 2003-08-15 選択的ｃｏｘ−２阻害物質としてのピリミジン誘導体

Country Status (8)

Country Link
US (1) US7235560B2 (enExample)
EP (1) EP1546128B1 (enExample)
JP (1) JP2006500372A (enExample)
AT (1) ATE325115T1 (enExample)
AU (1) AU2003258630A1 (enExample)
DE (1) DE60305053T2 (enExample)
ES (1) ES2263058T3 (enExample)
WO (1) WO2004018452A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60305053T2 (de) 2002-08-19 2006-08-31 Glaxo Group Ltd., Greenford Pyrimidinderivate als selektive cox-2-inhibitoren
GB0221443D0 (en) 2002-09-16 2002-10-23 Glaxo Group Ltd Pyridine derivates
SI1799196T1 (sl) 2004-10-08 2016-10-28 Forward Pharma A/S Farmacevtski sestavki z nadzorovanim sproščanjem, obsegajoči ester fumarne kisline
AU2006290465A1 (en) * 2005-09-15 2007-03-22 Orchid Research Laboratories Limited Novel pyrimidine carboxamides
EP1940382A2 (en) * 2005-10-07 2008-07-09 Aditech Pharma AB Combination therapy with fumaric acid esters for the treatment of autoimmune and/or inflammatory disorders
EP2564839B1 (en) 2009-01-09 2016-05-11 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
US20130012491A1 (en) * 2010-03-17 2013-01-10 Glaxo Group Limited Pyrimidine derivatives for use as sphingosine 1-phosphate 1 (s1p1) receptor agonists
WO2017210545A1 (en) * 2016-06-02 2017-12-07 Cadent Therapeutics, Inc. Potassium channel modulators
EP3571193B1 (en) 2017-01-23 2021-12-01 Cadent Therapeutics, Inc. Potassium channel modulators
MX2021004647A (es) 2018-10-22 2021-08-16 Novartis Ag Formas cristalinas de moduladores de los canales de potasio.
US20220348590A1 (en) * 2019-09-13 2022-11-03 The Board Institute, Inc. Cyclooxygenase-2 inhibitors and uses thereof

Citations (6)

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WO2004018452A1 (en) 2004-03-04
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