JP2006500360A5 - - Google Patents
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- Publication number
- JP2006500360A5 JP2006500360A5 JP2004528672A JP2004528672A JP2006500360A5 JP 2006500360 A5 JP2006500360 A5 JP 2006500360A5 JP 2004528672 A JP2004528672 A JP 2004528672A JP 2004528672 A JP2004528672 A JP 2004528672A JP 2006500360 A5 JP2006500360 A5 JP 2006500360A5
- Authority
- JP
- Japan
- Prior art keywords
- degrees
- solvent
- solution
- less
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002904 solvent Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0218811.8A GB0218811D0 (en) | 2002-08-14 | 2002-08-14 | Salts of morphine-6-glucuronide |
| GB0218811.8 | 2002-08-14 | ||
| PCT/GB2003/003562 WO2004016633A1 (en) | 2002-08-14 | 2003-08-14 | Salt of morphine-6-glucuronide |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2006500360A JP2006500360A (ja) | 2006-01-05 |
| JP2006500360A5 true JP2006500360A5 (enExample) | 2006-09-28 |
| JP4727990B2 JP4727990B2 (ja) | 2011-07-20 |
Family
ID=9942230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004528672A Expired - Fee Related JP4727990B2 (ja) | 2002-08-14 | 2003-08-14 | モルヒネ−６−グルクロニドの塩 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20060166900A1 (enExample) |
| EP (1) | EP1537132B1 (enExample) |
| JP (1) | JP4727990B2 (enExample) |
| KR (1) | KR101077501B1 (enExample) |
| AT (1) | ATE315041T1 (enExample) |
| AU (1) | AU2003255790B2 (enExample) |
| CA (1) | CA2494812C (enExample) |
| DE (1) | DE60303149T2 (enExample) |
| DK (1) | DK1537132T3 (enExample) |
| EA (1) | EA008212B1 (enExample) |
| ES (1) | ES2256790T3 (enExample) |
| GB (1) | GB0218811D0 (enExample) |
| IL (1) | IL166596A0 (enExample) |
| NO (1) | NO20051261L (enExample) |
| PL (1) | PL211031B1 (enExample) |
| WO (1) | WO2004016633A1 (enExample) |
| ZA (1) | ZA200501053B (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ561375A (en) | 2005-06-27 | 2011-06-30 | Biovail Lab Int Srl | Bupropion hydrobromide, and crystalline forms, compositions, and uses of this compound |
| FR2939437B1 (fr) * | 2008-12-10 | 2010-12-17 | Sanofi Aventis | Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique |
| FR2939796B1 (fr) * | 2008-12-11 | 2010-12-17 | Sanofi Aventis | Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique |
| CN107028968B (zh) * | 2016-02-03 | 2020-12-04 | 江苏恒瑞医药股份有限公司 | 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物 |
| US20180110725A1 (en) | 2016-10-21 | 2018-04-26 | Somniferum Labs LLC | Compositions, methods and kits for the safe inhaled delivery of targeted opioids for the treatment of pain and addiction |
| CN110054656B (zh) * | 2019-05-28 | 2021-02-02 | 宜昌人福药业有限责任公司 | 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法 |
| CN113831373B (zh) * | 2020-06-23 | 2023-05-16 | 宜昌人福药业有限责任公司 | 一种吗啡-6-葡萄糖苷酸脱水物杂质的合成方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4908389A (en) * | 1986-08-27 | 1990-03-13 | Warner-Lambert Company | Penetration enhancement system |
| FR2680786B1 (fr) * | 1991-09-04 | 1995-03-10 | Irepa | Procede de synthese de glucuronides d'epoxy-4,5 morphinanes. |
| DE4403709A1 (de) * | 1994-02-07 | 1995-08-10 | Lohmann Therapie Syst Lts | Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid |
| US5460826A (en) * | 1994-06-27 | 1995-10-24 | Alza Corporation | Morphine therapy |
| JPH10513485A (ja) * | 1995-11-29 | 1998-12-22 | ロラボ エセ エレ | オピエート性物質の糖結合体 |
| JP2001517669A (ja) * | 1997-09-25 | 2001-10-09 | エルティエス ローマン テラピー−ズュステーメ アーゲー | モルヒネアルカロイド類の酸添加塩類およびその応用 |
| US6740641B2 (en) * | 2001-07-27 | 2004-05-25 | Euro-Celtique, S.A. | Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain |
-
2002
- 2002-08-14 GB GBGB0218811.8A patent/GB0218811D0/en not_active Ceased
-
2003
- 2003-08-14 AU AU2003255790A patent/AU2003255790B2/en not_active Ceased
- 2003-08-14 DK DK03787894T patent/DK1537132T3/da active
- 2003-08-14 CA CA2494812A patent/CA2494812C/en not_active Expired - Fee Related
- 2003-08-14 PL PL373553A patent/PL211031B1/pl unknown
- 2003-08-14 DE DE60303149T patent/DE60303149T2/de not_active Expired - Lifetime
- 2003-08-14 US US10/524,149 patent/US20060166900A1/en not_active Abandoned
- 2003-08-14 AT AT03787894T patent/ATE315041T1/de active
- 2003-08-14 JP JP2004528672A patent/JP4727990B2/ja not_active Expired - Fee Related
- 2003-08-14 KR KR1020057002442A patent/KR101077501B1/ko not_active Expired - Fee Related
- 2003-08-14 EP EP03787894A patent/EP1537132B1/en not_active Expired - Lifetime
- 2003-08-14 ES ES03787894T patent/ES2256790T3/es not_active Expired - Lifetime
- 2003-08-14 EA EA200500175A patent/EA008212B1/ru not_active IP Right Cessation
- 2003-08-14 WO PCT/GB2003/003562 patent/WO2004016633A1/en not_active Ceased
-
2005
- 2005-01-31 IL IL16659605A patent/IL166596A0/xx not_active IP Right Cessation
- 2005-02-04 ZA ZA2005/01053A patent/ZA200501053B/en unknown
- 2005-03-11 NO NO20051261A patent/NO20051261L/no unknown
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