IL166596A0 - Salt of morphine-6-glucoronide - Google Patents

Salt of morphine-6-glucoronide

Info

Publication number
IL166596A0
IL166596A0 IL16659605A IL16659605A IL166596A0 IL 166596 A0 IL166596 A0 IL 166596A0 IL 16659605 A IL16659605 A IL 16659605A IL 16659605 A IL16659605 A IL 16659605A IL 166596 A0 IL166596 A0 IL 166596A0
Authority
IL
Israel
Prior art keywords
hbr
morphine
salt
glucoronide
medicament
Prior art date
Application number
IL16659605A
Other languages
English (en)
Original Assignee
Cenes Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cenes Ltd filed Critical Cenes Ltd
Publication of IL166596A0 publication Critical patent/IL166596A0/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL16659605A 2002-08-14 2005-01-31 Salt of morphine-6-glucoronide IL166596A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0218811.8A GB0218811D0 (en) 2002-08-14 2002-08-14 Salts of morphine-6-glucuronide
PCT/GB2003/003562 WO2004016633A1 (en) 2002-08-14 2003-08-14 Salt of morphine-6-glucuronide

Publications (1)

Publication Number Publication Date
IL166596A0 true IL166596A0 (en) 2006-01-15

Family

ID=9942230

Family Applications (1)

Application Number Title Priority Date Filing Date
IL16659605A IL166596A0 (en) 2002-08-14 2005-01-31 Salt of morphine-6-glucoronide

Country Status (17)

Country Link
US (1) US20060166900A1 (xx)
EP (1) EP1537132B1 (xx)
JP (1) JP4727990B2 (xx)
KR (1) KR101077501B1 (xx)
AT (1) ATE315041T1 (xx)
AU (1) AU2003255790B2 (xx)
CA (1) CA2494812C (xx)
DE (1) DE60303149T2 (xx)
DK (1) DK1537132T3 (xx)
EA (1) EA008212B1 (xx)
ES (1) ES2256790T3 (xx)
GB (1) GB0218811D0 (xx)
IL (1) IL166596A0 (xx)
NO (1) NO20051261L (xx)
PL (1) PL211031B1 (xx)
WO (1) WO2004016633A1 (xx)
ZA (1) ZA200501053B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1896002A4 (en) 2005-06-27 2009-11-25 Biovail Lab Int Srl BUPROPIONAL SALT FORMULATIONS WITH MODIFIED RELEASE
FR2939437B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
CN107028968B (zh) * 2016-02-03 2020-12-04 江苏恒瑞医药股份有限公司 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物
US20180110725A1 (en) 2016-10-21 2018-04-26 Somniferum Labs LLC Compositions, methods and kits for the safe inhaled delivery of targeted opioids for the treatment of pain and addiction
CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
CN113831373B (zh) * 2020-06-23 2023-05-16 宜昌人福药业有限责任公司 一种吗啡-6-葡萄糖苷酸脱水物杂质的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.
DE4403709A1 (de) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
WO1997021416A2 (es) * 1995-11-29 1997-06-19 Rolabo Sl Glicoconjugados de substancias opiaceas
SK4322000A3 (en) * 1997-09-25 2000-10-09 Lohmann Therapie Syst Lts Transdermal or transmucosal composition for administering morphine alkaloids, the application thereof, appropriate compounds and method for their producing
US6740641B2 (en) * 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain

Also Published As

Publication number Publication date
AU2003255790B2 (en) 2010-05-27
CA2494812A1 (en) 2004-02-26
EA200500175A1 (ru) 2005-08-25
ZA200501053B (en) 2005-10-26
NO20051261L (no) 2005-03-11
AU2003255790A1 (en) 2004-03-03
JP2006500360A (ja) 2006-01-05
EP1537132A1 (en) 2005-06-08
GB0218811D0 (en) 2002-09-18
DE60303149T2 (de) 2006-09-28
ATE315041T1 (de) 2006-02-15
CA2494812C (en) 2011-03-08
US20060166900A1 (en) 2006-07-27
PL211031B1 (pl) 2012-04-30
JP4727990B2 (ja) 2011-07-20
DE60303149D1 (de) 2006-03-30
WO2004016633A1 (en) 2004-02-26
KR101077501B1 (ko) 2011-10-28
KR20050055710A (ko) 2005-06-13
EA008212B1 (ru) 2007-04-27
PL373553A1 (en) 2005-09-05
DK1537132T3 (da) 2006-05-08
ES2256790T3 (es) 2006-07-16
EP1537132B1 (en) 2006-01-04

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IL166596A0 (en) Salt of morphine-6-glucoronide
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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees