JP2006500360A5 - - Google Patents

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Publication number
JP2006500360A5
JP2006500360A5 JP2004528672A JP2004528672A JP2006500360A5 JP 2006500360 A5 JP2006500360 A5 JP 2006500360A5 JP 2004528672 A JP2004528672 A JP 2004528672A JP 2004528672 A JP2004528672 A JP 2004528672A JP 2006500360 A5 JP2006500360 A5 JP 2006500360A5
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JP
Japan
Prior art keywords
degrees
solvent
solution
less
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2004528672A
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English (en)
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JP4727990B2 (ja
JP2006500360A (ja
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Publication date
Priority claimed from GBGB0218811.8A external-priority patent/GB0218811D0/en
Application filed filed Critical
Publication of JP2006500360A publication Critical patent/JP2006500360A/ja
Publication of JP2006500360A5 publication Critical patent/JP2006500360A5/ja
Application granted granted Critical
Publication of JP4727990B2 publication Critical patent/JP4727990B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Claims (1)

  1. 上記溶液および溶媒が−１５℃以下である、請求項１０に記載の方法。
JP2004528672A 2002-08-14 2003-08-14 モルヒネ−６−グルクロニドの塩 Expired - Fee Related JP4727990B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0218811.8 2002-08-14
GBGB0218811.8A GB0218811D0 (en) 2002-08-14 2002-08-14 Salts of morphine-6-glucuronide
PCT/GB2003/003562 WO2004016633A1 (en) 2002-08-14 2003-08-14 Salt of morphine-6-glucuronide

Publications (3)

Publication Number Publication Date
JP2006500360A JP2006500360A (ja) 2006-01-05
JP2006500360A5 true JP2006500360A5 (ja) 2006-09-28
JP4727990B2 JP4727990B2 (ja) 2011-07-20

Family

ID=9942230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004528672A Expired - Fee Related JP4727990B2 (ja) 2002-08-14 2003-08-14 モルヒネ−６−グルクロニドの塩

Country Status (17)

Country Link
US (1) US20060166900A1 (ja)
EP (1) EP1537132B1 (ja)
JP (1) JP4727990B2 (ja)
KR (1) KR101077501B1 (ja)
AT (1) ATE315041T1 (ja)
AU (1) AU2003255790B2 (ja)
CA (1) CA2494812C (ja)
DE (1) DE60303149T2 (ja)
DK (1) DK1537132T3 (ja)
EA (1) EA008212B1 (ja)
ES (1) ES2256790T3 (ja)
GB (1) GB0218811D0 (ja)
IL (1) IL166596A0 (ja)
NO (1) NO20051261L (ja)
PL (1) PL211031B1 (ja)
WO (1) WO2004016633A1 (ja)
ZA (1) ZA200501053B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7884136B2 (en) 2005-06-27 2011-02-08 Biovail Laboratories International S.R.L. Modified-release formulations of a bupropion salt
FR2939437B1 (fr) * 2008-12-10 2010-12-17 Sanofi Aventis Derives de morphine-6-glucuronide, leur preparation et leur application en therapeutique
FR2939796B1 (fr) * 2008-12-11 2010-12-17 Sanofi Aventis Derives bicycliques de morphine-6-glucuronide, leur preparation et leur application en therapeutique
CN107028968B (zh) * 2016-02-03 2020-12-04 江苏恒瑞医药股份有限公司 一种含有葡萄糖醛酸吗啡或其可药用盐的药物组合物
EP3528873A2 (en) 2016-10-21 2019-08-28 Somniferum Labs LLC Apparatus for controlled delivery of opioid and other medications
CN110054656B (zh) * 2019-05-28 2021-02-02 宜昌人福药业有限责任公司 一种10-羰基/羟基吗啡-6-葡萄糖苷酸的合成方法
CN113831373B (zh) * 2020-06-23 2023-05-16 宜昌人福药业有限责任公司 一种吗啡-6-葡萄糖苷酸脱水物杂质的合成方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4908389A (en) * 1986-08-27 1990-03-13 Warner-Lambert Company Penetration enhancement system
FR2680786B1 (fr) * 1991-09-04 1995-03-10 Irepa Procede de synthese de glucuronides d'epoxy-4,5 morphinanes.
DE4403709A1 (de) * 1994-02-07 1995-08-10 Lohmann Therapie Syst Lts Pharmazeutische Zusammensetzung zur systemischen transdermalen Verabreichung mit dem Wirkstoff Morphin-6-glucuronid
US5460826A (en) * 1994-06-27 1995-10-24 Alza Corporation Morphine therapy
EP0816375A1 (en) * 1995-11-29 1998-01-07 Rolabo Sl Glycoconjugates of opiated substances
ID26296A (id) * 1997-09-25 2000-12-14 Lohmann Therapie Syst Lts Garam penambahan asam dari alkaloid morfin dan penggunaannya
US6740641B2 (en) * 2001-07-27 2004-05-25 Euro-Celtique, S.A. Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain

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