JP2005538809A - 医療装置のための制御可能な薬剤放出勾配コーティング - Google Patents

医療装置のための制御可能な薬剤放出勾配コーティング Download PDF

Info

Publication number
JP2005538809A
JP2005538809A JP2004538458A JP2004538458A JP2005538809A JP 2005538809 A JP2005538809 A JP 2005538809A JP 2004538458 A JP2004538458 A JP 2004538458A JP 2004538458 A JP2004538458 A JP 2004538458A JP 2005538809 A JP2005538809 A JP 2005538809A
Authority
JP
Japan
Prior art keywords
polymer
coating
layer
drug
stent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004538458A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005538809A5 (enExample
Inventor
トッド キャンベル
Original Assignee
メドトロニック ヴァスキュラー インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by メドトロニック ヴァスキュラー インコーポレイテッド filed Critical メドトロニック ヴァスキュラー インコーポレイテッド
Publication of JP2005538809A publication Critical patent/JP2005538809A/ja
Publication of JP2005538809A5 publication Critical patent/JP2005538809A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/08Materials for coatings
    • A61L29/085Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/34Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L29/00Materials for catheters, medical tubing, cannulae, or endoscopes or for coating catheters
    • A61L29/14Materials characterised by their function or physical properties, e.g. lubricating compositions
    • A61L29/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/10Macromolecular materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606Coatings
    • A61L2300/608Coatings having two or more layers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2004538458A 2002-09-18 2003-09-18 医療装置のための制御可能な薬剤放出勾配コーティング Pending JP2005538809A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41185202P 2002-09-18 2002-09-18
PCT/US2003/030010 WO2004026361A1 (en) 2002-09-18 2003-09-18 Controllable drug releasing gradient coatings for medical devices

Publications (2)

Publication Number Publication Date
JP2005538809A true JP2005538809A (ja) 2005-12-22
JP2005538809A5 JP2005538809A5 (enExample) 2006-11-02

Family

ID=32030751

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004538458A Pending JP2005538809A (ja) 2002-09-18 2003-09-18 医療装置のための制御可能な薬剤放出勾配コーティング

Country Status (5)

Country Link
US (1) US20070078513A1 (enExample)
EP (1) EP1539270A1 (enExample)
JP (1) JP2005538809A (enExample)
AU (1) AU2003275190A1 (enExample)
WO (1) WO2004026361A1 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009247506A (ja) * 2008-04-03 2009-10-29 Kaneka Corp ステント
JP2009541005A (ja) * 2006-06-26 2009-11-26 デイビッド ワイ. バダウィ, 眼内インプラント、ならびにそのための方法およびキット
JP2010517713A (ja) * 2007-02-14 2010-05-27 シャンドン インテク メディカル テクノロジー カンパニー リミテッド 非対称性の薬剤放出が制御されたコーティングを有する冠状動脈ステント
JP2010522624A (ja) * 2007-03-28 2010-07-08 ボストン サイエンティフィック サイムド,インコーポレイテッド 治療剤の放出のための生体侵食性層を有する医療装置
JP2011512957A (ja) * 2008-02-29 2011-04-28 スミス アンド ネフュー インコーポレーテッド 生物医学的応用のための勾配コーティング
US8439972B2 (en) 2010-02-05 2013-05-14 Sight Sciences, Inc. Intraocular implants and related kits and methods
JP2013523258A (ja) * 2010-03-31 2013-06-17 アボット カーディオヴァスキュラー システムズ インコーポレイテッド 埋込み型デバイス用の吸収性コーティング
US8894603B2 (en) 2012-03-20 2014-11-25 Sight Sciences, Inc. Ocular delivery systems and methods
KR20160094375A (ko) * 2013-10-31 2016-08-09 라이프테크 사이언티픽 (센젠) 컴퍼니 리미티드 흡수성 철계 합금 스텐트
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
US11504270B1 (en) 2019-09-27 2022-11-22 Sight Sciences, Inc. Ocular delivery systems and methods

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6774278B1 (en) * 1995-06-07 2004-08-10 Cook Incorporated Coated implantable medical device
US7550005B2 (en) * 1995-06-07 2009-06-23 Cook Incorporated Coated implantable medical device
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US7896914B2 (en) * 1995-06-07 2011-03-01 Cook Incorporated Coated implantable medical device
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US8741378B1 (en) 2001-06-27 2014-06-03 Advanced Cardiovascular Systems, Inc. Methods of coating an implantable device
WO2003002243A2 (en) 2001-06-27 2003-01-09 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US20050033417A1 (en) * 2003-07-31 2005-02-10 John Borges Coating for controlled release of a therapeutic agent
US20050064005A1 (en) * 2003-08-13 2005-03-24 Dinh Thomas Q. Active agent delivery systems including a miscible polymer blend, medical devices, and methods
US20050037052A1 (en) * 2003-08-13 2005-02-17 Medtronic Vascular, Inc. Stent coating with gradient porosity
US8801692B2 (en) 2003-09-24 2014-08-12 Medtronic Vascular, Inc. Gradient coated stent and method of fabrication
GB0402838D0 (en) 2004-02-10 2004-03-17 Univ Belfast Method
US7066935B2 (en) 2004-04-30 2006-06-27 Medtronic, Inc. Ion eluting tuna device
ATE374627T1 (de) * 2004-05-20 2007-10-15 Boston Scient Ltd Medizinische vorrichtungen und verfahren zu ihrer herstellung
JP2006028085A (ja) * 2004-07-15 2006-02-02 Shinshu Univ 血中コレステロール濃度低下作用物質
JP4876916B2 (ja) * 2004-07-30 2012-02-15 株式会社カネカ ステント
CN101052362A (zh) * 2004-09-08 2007-10-10 株式会社钟化 生物体留置用支架
WO2006027994A1 (ja) * 2004-09-08 2006-03-16 Kaneka Corporation 生体留置用ステント
US20080077232A1 (en) * 2004-09-08 2008-03-27 Kaneka Corporation Stent for Placement in Body
US9452001B2 (en) * 2005-02-22 2016-09-27 Tecres S.P.A. Disposable device for treatment of infections of human limbs
JP4967136B2 (ja) * 2005-06-24 2012-07-04 国立大学法人 東京医科歯科大学 薬剤溶出性ステント
US10029034B2 (en) * 2005-12-15 2018-07-24 CARDINAL HEALTH SWITZERLAND 515 GmbH Drug-eluting articles with improved drug release profiles
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8852625B2 (en) 2006-04-26 2014-10-07 Micell Technologies, Inc. Coatings containing multiple drugs
US9737640B2 (en) 2006-11-20 2017-08-22 Lutonix, Inc. Drug releasing coatings for medical devices
US20080276935A1 (en) 2006-11-20 2008-11-13 Lixiao Wang Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs
US8430055B2 (en) 2008-08-29 2013-04-30 Lutonix, Inc. Methods and apparatuses for coating balloon catheters
US9700704B2 (en) 2006-11-20 2017-07-11 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8425459B2 (en) * 2006-11-20 2013-04-23 Lutonix, Inc. Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent
US8414525B2 (en) * 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8998846B2 (en) 2006-11-20 2015-04-07 Lutonix, Inc. Drug releasing coatings for balloon catheters
US8414910B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8414909B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Drug releasing coatings for medical devices
US8414526B2 (en) 2006-11-20 2013-04-09 Lutonix, Inc. Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids
EP2097140B1 (en) * 2006-12-20 2012-09-26 Arkema Inc. Polymer encapsulation and/or binding
US8080055B2 (en) 2006-12-28 2011-12-20 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US7854941B2 (en) 2007-02-12 2010-12-21 The University Of Southern Mississippi Method of attaching drug compounds to non-reactive polymer surfaces
ATE551077T1 (de) 2007-04-17 2012-04-15 Medtronic Inc Minderung einer infektion in zusammenhang mit einer medizinischen vorrichtung
JP4596335B2 (ja) * 2007-12-07 2010-12-08 東洋紡績株式会社 神経再生誘導管の製造方法
US8057876B2 (en) * 2008-02-25 2011-11-15 Abbott Cardiovascular Systems Inc. Bioabsorbable stent with layers having different degradation rates
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US8206636B2 (en) 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US10898620B2 (en) 2008-06-20 2021-01-26 Razmodics Llc Composite stent having multi-axial flexibility and method of manufacture thereof
US8206635B2 (en) * 2008-06-20 2012-06-26 Amaranth Medical Pte. Stent fabrication via tubular casting processes
US8445008B2 (en) 2008-10-17 2013-05-21 Medtronic, Inc. Reduction of infection associated with medical device
EP2391397A2 (en) * 2009-02-02 2011-12-07 Medtronic, Inc. Composite antimicrobial accessory including a membrane layer and a porous layer
US9492587B2 (en) * 2009-04-13 2016-11-15 Abbott Cardiovascular Systems Inc. Stent made from an ultra high molecular weight bioabsorbable polymer with high fatigue and fracture resistance
US8858983B2 (en) 2009-04-30 2014-10-14 Medtronic, Inc. Antioxidants and antimicrobial accessories including antioxidants
US8652505B2 (en) * 2010-03-04 2014-02-18 Southwest Research Institute Coating for medical implants
WO2011119573A1 (en) 2010-03-23 2011-09-29 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US8911427B2 (en) 2010-12-28 2014-12-16 Medtronic, Inc. Therapeutic agent reservoir delivery system
JP2014515621A (ja) * 2011-01-13 2014-07-03 イノビア,リミティド ライアビリティー カンパニー 腔内薬物アプリケータ及び身体の病変血管を治療する方法
US10232090B2 (en) 2013-08-23 2019-03-19 Southwest Research Institute Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants
EP2918263B1 (en) * 2014-03-13 2017-05-03 Sabanci Üniversitesi Pharmaceutical drug delivery system
CN111110413A (zh) * 2020-03-02 2020-05-08 南京浩衍鼎业科技技术有限公司 一种具有微孔阵列的颅内可降解生物支架及其制备方法
CN112370634B (zh) * 2020-11-03 2023-04-25 山东华安生物科技有限公司 一种复合管及其制备方法和应用
CN113730042B (zh) * 2021-09-09 2022-10-11 北京理工大学 具有多级微纳结构的骨科植入体及其制造方法
CN116173381A (zh) * 2022-12-19 2023-05-30 上海百心安生物技术股份有限公司 一种新型可控制药物释放的药物球囊导管及其应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4842867A (en) * 1986-05-09 1989-06-27 Alza Corporation Pulsed drug delivery of doxylamine
US5021053A (en) * 1989-07-14 1991-06-04 Alza Corporation Oral osmotic device with hydrogel driving member
US5049138A (en) * 1989-11-13 1991-09-17 Boston Scientific Corporation Catheter with dissolvable tip
WO1993006792A1 (en) * 1991-10-04 1993-04-15 Scimed Life Systems, Inc. Biodegradable drug delivery vascular stent
US5260002A (en) * 1991-12-23 1993-11-09 Vanderbilt University Method and apparatus for producing uniform polymeric spheres
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
US5824048A (en) * 1993-04-26 1998-10-20 Medtronic, Inc. Method for delivering a therapeutic substance to a body lumen
US5362718A (en) * 1994-04-18 1994-11-08 American Home Products Corporation Rapamycin hydroxyesters
US5788979A (en) * 1994-07-22 1998-08-04 Inflow Dynamics Inc. Biodegradable coating with inhibitory properties for application to biocompatible materials
US6020004A (en) * 1997-04-17 2000-02-01 Amgen Inc. Biodegradable microparticles for the sustained delivery of therapeutic drugs
US6015815A (en) * 1997-09-26 2000-01-18 Abbott Laboratories Tetrazole-containing rapamycin analogs with shortened half-lives
DK1035834T3 (da) * 1997-12-05 2002-07-08 Alza Corp Osmotisk doseringsform omfattende en første og anden coating
US6245357B1 (en) * 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
US7208010B2 (en) * 2000-10-16 2007-04-24 Conor Medsystems, Inc. Expandable medical device for delivery of beneficial agent
US6335029B1 (en) * 1998-08-28 2002-01-01 Scimed Life Systems, Inc. Polymeric coatings for controlled delivery of active agents
EP1152709B1 (en) * 1999-02-02 2005-01-12 Wright Medical Technology, Inc. Controlled release composite
US6368658B1 (en) * 1999-04-19 2002-04-09 Scimed Life Systems, Inc. Coating medical devices using air suspension
US6716444B1 (en) * 2000-09-28 2004-04-06 Advanced Cardiovascular Systems, Inc. Barriers for polymer-coated implantable medical devices and methods for making the same
AU9486901A (en) * 2000-09-29 2002-04-08 Cordis Corp Coated medical devices
US6471980B2 (en) * 2000-12-22 2002-10-29 Avantec Vascular Corporation Intravascular delivery of mycophenolic acid
US7396539B1 (en) * 2002-06-21 2008-07-08 Advanced Cardiovascular Systems, Inc. Stent coatings with engineered drug release rate
US7232573B1 (en) * 2002-09-26 2007-06-19 Advanced Cardiovascular Systems, Inc. Stent coatings containing self-assembled monolayers
US7491234B2 (en) * 2002-12-03 2009-02-17 Boston Scientific Scimed, Inc. Medical devices for delivery of therapeutic agents
US7169404B2 (en) * 2003-07-30 2007-01-30 Advanced Cardiovasular Systems, Inc. Biologically absorbable coatings for implantable devices and methods for fabricating the same

Cited By (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10314742B2 (en) 2006-06-26 2019-06-11 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
JP2009541005A (ja) * 2006-06-26 2009-11-26 デイビッド ワイ. バダウィ, 眼内インプラント、ならびにそのための方法およびキット
US10398597B2 (en) 2006-06-26 2019-09-03 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US9486361B2 (en) 2006-06-26 2016-11-08 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US11389328B2 (en) 2006-06-26 2022-07-19 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US9370443B2 (en) 2006-06-26 2016-06-21 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
US11865041B2 (en) 2006-06-26 2024-01-09 Sight Sciences, Inc. Intraocular implants and methods and kits therefor
JP2010517713A (ja) * 2007-02-14 2010-05-27 シャンドン インテク メディカル テクノロジー カンパニー リミテッド 非対称性の薬剤放出が制御されたコーティングを有する冠状動脈ステント
JP2010522624A (ja) * 2007-03-28 2010-07-08 ボストン サイエンティフィック サイムド,インコーポレイテッド 治療剤の放出のための生体侵食性層を有する医療装置
JP2015057126A (ja) * 2008-02-29 2015-03-26 スミス アンド ネフュー インコーポレーテッド 生物医学的応用のための勾配コーティング
US9011965B2 (en) 2008-02-29 2015-04-21 Smith & Nephew, Inc. Gradient coating for biomedical applications
JP2017060889A (ja) * 2008-02-29 2017-03-30 スミス アンド ネフュー インコーポレイテッド 生物医学的応用のための勾配コーティング
JP2011512957A (ja) * 2008-02-29 2011-04-28 スミス アンド ネフュー インコーポレーテッド 生物医学的応用のための勾配コーティング
JP2009247506A (ja) * 2008-04-03 2009-10-29 Kaneka Corp ステント
US12171689B2 (en) 2010-02-05 2024-12-24 Sight Sciences, Inc. Intraocular implants and related kits and methods
US8876898B2 (en) 2010-02-05 2014-11-04 Sight Sciences, Inc. Intraocular implants and related kits and methods
US8529622B2 (en) 2010-02-05 2013-09-10 Sight Sciences, Inc. Intraocular implants and related kits and methods
US11166847B2 (en) 2010-02-05 2021-11-09 Sight Sciences, Inc. Intraocular implants and related kits and methods
US8439972B2 (en) 2010-02-05 2013-05-14 Sight Sciences, Inc. Intraocular implants and related kits and methods
US10406030B2 (en) 2010-02-05 2019-09-10 Sight Sciences, Inc. Intraocular implants and related kits and methods
JP2013523258A (ja) * 2010-03-31 2013-06-17 アボット カーディオヴァスキュラー システムズ インコーポレイテッド 埋込み型デバイス用の吸収性コーティング
JP2016193203A (ja) * 2010-03-31 2016-11-17 アボット カーディオヴァスキュラー システムズ インコーポレイテッド 埋込み型デバイス用の吸収性コーティング
US9095412B2 (en) 2012-03-20 2015-08-04 Sight Sciences, Inc. Ocular delivery systems and methods
US11389327B2 (en) 2012-03-20 2022-07-19 Sight Sciences, Inc. Ocular delivery systems and methods
US10179066B2 (en) 2012-03-20 2019-01-15 Sight Sciences, Inc. Ocular delivery systems and methods
US9895258B2 (en) 2012-03-20 2018-02-20 Sight Sciences, Inc. Ocular delivery systems and methods
US9855167B2 (en) 2012-03-20 2018-01-02 Sight Sciences, Inc. Ocular delivery systems and methods
US10857027B2 (en) 2012-03-20 2020-12-08 Sight Sciences, Inc. Ocular delivery systems and methods
US12350192B2 (en) 2012-03-20 2025-07-08 Sight Sciences, Inc. Ocular delivery systems and methods
US10888453B2 (en) 2012-03-20 2021-01-12 Sight Sciences, Inc. Ocular delivery systems and methods
US8894603B2 (en) 2012-03-20 2014-11-25 Sight Sciences, Inc. Ocular delivery systems and methods
US12127974B2 (en) 2012-03-20 2024-10-29 Sight Sciences, Inc. Ocular delivery systems and methods
US11116660B2 (en) 2012-03-20 2021-09-14 Sight Sciences, Inc. Ocular delivery systems and methods
US12127973B2 (en) 2012-03-20 2024-10-29 Sight Sciences, Inc. Ocular delivery systems and methods
US11344447B2 (en) 2012-03-20 2022-05-31 Sight Sciences, Inc. Ocular delivery systems and methods
US12042428B2 (en) 2012-03-20 2024-07-23 Sight Sciences, Inc. Ocular delivery systems and methods
US11951037B2 (en) 2012-03-20 2024-04-09 Sight Sciences, Inc. Ocular delivery systems and methods
US11471324B2 (en) 2012-03-20 2022-10-18 Sight Sciences, Inc. Ocular delivery systems and methods
US9216109B2 (en) 2012-03-20 2015-12-22 Sight Sciences, Inc. Ocular delivery systems and methods
US11617679B2 (en) 2012-03-20 2023-04-04 Sight Sciences, Inc. Ocular delivery systems and methods
KR20160094375A (ko) * 2013-10-31 2016-08-09 라이프테크 사이언티픽 (센젠) 컴퍼니 리미티드 흡수성 철계 합금 스텐트
KR20160094376A (ko) * 2013-10-31 2016-08-09 라이프테크 사이언티픽 (센젠) 컴퍼니 리미티드 흡수성 철계 합금 스텐트
KR102202431B1 (ko) 2013-10-31 2021-01-12 바이오틱스 메디컬 (선전) 컴퍼니 리미티드 흡수성 철계 합금 스텐트
KR102201025B1 (ko) 2013-10-31 2021-01-08 바이오틱스 메디컬 (선전) 컴퍼니 리미티드 흡수성 철계 합금 스텐트
US11872158B2 (en) 2015-03-31 2024-01-16 Sight Sciences, Inc. Ocular delivery systems and methods
US10299958B2 (en) 2015-03-31 2019-05-28 Sight Sciences, Inc. Ocular delivery systems and methods
US11090188B2 (en) 2015-03-31 2021-08-17 Sight Sciences, Inc. Ocular delivery systems and methods
US12213914B2 (en) 2015-03-31 2025-02-04 Sight Sciences, Inc. Ocular delivery systems and methods
US11857460B2 (en) 2019-09-27 2024-01-02 Sight Sciences, Inc. Ocular delivery systems and methods
US11504270B1 (en) 2019-09-27 2022-11-22 Sight Sciences, Inc. Ocular delivery systems and methods

Also Published As

Publication number Publication date
AU2003275190A1 (en) 2004-04-08
US20070078513A1 (en) 2007-04-05
WO2004026361A1 (en) 2004-04-01
EP1539270A1 (en) 2005-06-15

Similar Documents

Publication Publication Date Title
JP2005538809A (ja) 医療装置のための制御可能な薬剤放出勾配コーティング
US6918929B2 (en) Drug-polymer coated stent with pegylated styrenic block copolymers
AU2003277023B2 (en) Apparatus and method for delivery of mitomycin through an eluting biocompatible implantable medical device
JP3803857B2 (ja) 活性剤の制御された送達のためのポリマーコーティング
US6713119B2 (en) Biocompatible coating for a prosthesis and a method of forming the same
JP4493655B2 (ja) 薬物ポリマコーティングをステントに施す方法
US6379381B1 (en) Porous prosthesis and a method of depositing substances into the pores
US6287628B1 (en) Porous prosthesis and a method of depositing substances into the pores
US8518097B2 (en) Plasticized stent coatings
US20070134288A1 (en) Anti-adhesion agents for drug coatings
US9254350B2 (en) Implantable medical devices having bioabsorbable primer polymer coatings
JP2005523045A (ja) 持効性の薬剤送出系を被覆したステント及びその使用方法
JP2004526499A (ja) 複数層ポリマーコーティングを有する薬物添加ステント
JP2008509742A (ja) ナノ多孔質層を備える医療用デバイスおよびそれを作製するための方法
JP2005536263A (ja) 医療用インプラントのための薬剤溶出コーティング
EP1214108A1 (en) A porous prosthesis and a method of depositing substances into the pores
JP2004524868A (ja) 被覆医用器具及びその滅菌方法
US20040230298A1 (en) Drug-polymer coated stent with polysulfone and styrenic block copolymer
CN101631514A (zh) 用于经皮冠状动脉介入的多药物洗脱冠状动脉支架
EP2101683A2 (en) Multiple drug-eluting coronary artery stent for percutaneous coronary artery intervention
EP2086600B1 (en) Stents with drug eluting coatings
WO2004064910A1 (ja) 生体留置用ステント
Costa Drug-coated stents for restenosis

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060915

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060915

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090928

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100308