JP2005538809A5 - - Google Patents
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- Publication number
- JP2005538809A5 JP2005538809A5 JP2004538458A JP2004538458A JP2005538809A5 JP 2005538809 A5 JP2005538809 A5 JP 2005538809A5 JP 2004538458 A JP2004538458 A JP 2004538458A JP 2004538458 A JP2004538458 A JP 2004538458A JP 2005538809 A5 JP2005538809 A5 JP 2005538809A5
- Authority
- JP
- Japan
- Prior art keywords
- medical implant
- stent
- poly
- layer
- implant according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 claims 15
- 150000001875 compounds Chemical class 0.000 claims 12
- 239000007943 implant Substances 0.000 claims 11
- 229920000642 polymer Polymers 0.000 claims 8
- 239000003120 macrolide antibiotic agent Substances 0.000 claims 6
- 208000037803 restenosis Diseases 0.000 claims 6
- 239000011248 coating agent Substances 0.000 claims 5
- 238000000576 coating method Methods 0.000 claims 5
- 102000008186 Collagen Human genes 0.000 claims 4
- 108010035532 Collagen Proteins 0.000 claims 4
- 229920001436 collagen Polymers 0.000 claims 4
- -1 catheter Substances 0.000 claims 3
- 230000000704 physical effect Effects 0.000 claims 3
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 3
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 3
- 229960002930 sirolimus Drugs 0.000 claims 3
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 claims 2
- 239000002202 Polyethylene glycol Substances 0.000 claims 2
- 229920000954 Polyglycolide Polymers 0.000 claims 2
- 239000004793 Polystyrene Substances 0.000 claims 2
- 229920002678 cellulose Polymers 0.000 claims 2
- 239000001913 cellulose Substances 0.000 claims 2
- 229920001577 copolymer Polymers 0.000 claims 2
- 150000002118 epoxides Chemical class 0.000 claims 2
- 239000005038 ethylene vinyl acetate Substances 0.000 claims 2
- 229920001200 poly(ethylene-vinyl acetate) Polymers 0.000 claims 2
- 229920000747 poly(lactic acid) Polymers 0.000 claims 2
- 229920001610 polycaprolactone Polymers 0.000 claims 2
- 229920000728 polyester Polymers 0.000 claims 2
- 229920001223 polyethylene glycol Polymers 0.000 claims 2
- 229920001296 polysiloxane Polymers 0.000 claims 2
- 229920002223 polystyrene Polymers 0.000 claims 2
- 229920001343 polytetrafluoroethylene Polymers 0.000 claims 2
- 239000004810 polytetrafluoroethylene Substances 0.000 claims 2
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 2
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 2
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 2
- 230000002792 vascular Effects 0.000 claims 2
- 230000004888 barrier function Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000000523 sample Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US41185202P | 2002-09-18 | 2002-09-18 | |
| PCT/US2003/030010 WO2004026361A1 (en) | 2002-09-18 | 2003-09-18 | Controllable drug releasing gradient coatings for medical devices |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005538809A JP2005538809A (ja) | 2005-12-22 |
| JP2005538809A5 true JP2005538809A5 (enExample) | 2006-11-02 |
Family
ID=32030751
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004538458A Pending JP2005538809A (ja) | 2002-09-18 | 2003-09-18 | 医療装置のための制御可能な薬剤放出勾配コーティング |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20070078513A1 (enExample) |
| EP (1) | EP1539270A1 (enExample) |
| JP (1) | JP2005538809A (enExample) |
| AU (1) | AU2003275190A1 (enExample) |
| WO (1) | WO2004026361A1 (enExample) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6774278B1 (en) * | 1995-06-07 | 2004-08-10 | Cook Incorporated | Coated implantable medical device |
| US7550005B2 (en) * | 1995-06-07 | 2009-06-23 | Cook Incorporated | Coated implantable medical device |
| US7611533B2 (en) * | 1995-06-07 | 2009-11-03 | Cook Incorporated | Coated implantable medical device |
| US7896914B2 (en) * | 1995-06-07 | 2011-03-01 | Cook Incorporated | Coated implantable medical device |
| US7351421B2 (en) * | 1996-11-05 | 2008-04-01 | Hsing-Wen Sung | Drug-eluting stent having collagen drug carrier chemically treated with genipin |
| US8741378B1 (en) | 2001-06-27 | 2014-06-03 | Advanced Cardiovascular Systems, Inc. | Methods of coating an implantable device |
| WO2003002243A2 (en) | 2001-06-27 | 2003-01-09 | Remon Medical Technologies Ltd. | Method and device for electrochemical formation of therapeutic species in vivo |
| US20050033417A1 (en) * | 2003-07-31 | 2005-02-10 | John Borges | Coating for controlled release of a therapeutic agent |
| US20050064005A1 (en) * | 2003-08-13 | 2005-03-24 | Dinh Thomas Q. | Active agent delivery systems including a miscible polymer blend, medical devices, and methods |
| US20050037052A1 (en) * | 2003-08-13 | 2005-02-17 | Medtronic Vascular, Inc. | Stent coating with gradient porosity |
| US8801692B2 (en) | 2003-09-24 | 2014-08-12 | Medtronic Vascular, Inc. | Gradient coated stent and method of fabrication |
| GB0402838D0 (en) | 2004-02-10 | 2004-03-17 | Univ Belfast | Method |
| US7066935B2 (en) | 2004-04-30 | 2006-06-27 | Medtronic, Inc. | Ion eluting tuna device |
| ATE374627T1 (de) * | 2004-05-20 | 2007-10-15 | Boston Scient Ltd | Medizinische vorrichtungen und verfahren zu ihrer herstellung |
| JP2006028085A (ja) * | 2004-07-15 | 2006-02-02 | Shinshu Univ | 血中コレステロール濃度低下作用物質 |
| JP4876916B2 (ja) * | 2004-07-30 | 2012-02-15 | 株式会社カネカ | ステント |
| CN101052362A (zh) * | 2004-09-08 | 2007-10-10 | 株式会社钟化 | 生物体留置用支架 |
| WO2006027994A1 (ja) * | 2004-09-08 | 2006-03-16 | Kaneka Corporation | 生体留置用ステント |
| US20080077232A1 (en) * | 2004-09-08 | 2008-03-27 | Kaneka Corporation | Stent for Placement in Body |
| US9452001B2 (en) * | 2005-02-22 | 2016-09-27 | Tecres S.P.A. | Disposable device for treatment of infections of human limbs |
| JP4967136B2 (ja) * | 2005-06-24 | 2012-07-04 | 国立大学法人 東京医科歯科大学 | 薬剤溶出性ステント |
| US10029034B2 (en) * | 2005-12-15 | 2018-07-24 | CARDINAL HEALTH SWITZERLAND 515 GmbH | Drug-eluting articles with improved drug release profiles |
| US8840660B2 (en) | 2006-01-05 | 2014-09-23 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
| US8852625B2 (en) | 2006-04-26 | 2014-10-07 | Micell Technologies, Inc. | Coatings containing multiple drugs |
| US7909789B2 (en) | 2006-06-26 | 2011-03-22 | Sight Sciences, Inc. | Intraocular implants and methods and kits therefor |
| US9737640B2 (en) | 2006-11-20 | 2017-08-22 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US20080276935A1 (en) | 2006-11-20 | 2008-11-13 | Lixiao Wang | Treatment of asthma and chronic obstructive pulmonary disease with anti-proliferate and anti-inflammatory drugs |
| US8430055B2 (en) | 2008-08-29 | 2013-04-30 | Lutonix, Inc. | Methods and apparatuses for coating balloon catheters |
| US9700704B2 (en) | 2006-11-20 | 2017-07-11 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| US8425459B2 (en) * | 2006-11-20 | 2013-04-23 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising a therapeutic agent and a contrast agent |
| US8414525B2 (en) * | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8998846B2 (en) | 2006-11-20 | 2015-04-07 | Lutonix, Inc. | Drug releasing coatings for balloon catheters |
| US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8414909B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| US8414526B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Medical device rapid drug releasing coatings comprising oils, fatty acids, and/or lipids |
| EP2097140B1 (en) * | 2006-12-20 | 2012-09-26 | Arkema Inc. | Polymer encapsulation and/or binding |
| US8080055B2 (en) | 2006-12-28 | 2011-12-20 | Boston Scientific Scimed, Inc. | Bioerodible endoprostheses and methods of making the same |
| US7854941B2 (en) | 2007-02-12 | 2010-12-21 | The University Of Southern Mississippi | Method of attaching drug compounds to non-reactive polymer surfaces |
| US8591931B2 (en) * | 2007-02-14 | 2013-11-26 | Shangdong Intech Medical Technology Co., Ltd | Coronary stent with asymmetric drug releasing controlled coating |
| WO2008121702A2 (en) * | 2007-03-28 | 2008-10-09 | Boston Scientific Scimed, Inc. | Medical devices having bioerodable layers for the release of therapeutic agents |
| ATE551077T1 (de) | 2007-04-17 | 2012-04-15 | Medtronic Inc | Minderung einer infektion in zusammenhang mit einer medizinischen vorrichtung |
| JP4596335B2 (ja) * | 2007-12-07 | 2010-12-08 | 東洋紡績株式会社 | 神経再生誘導管の製造方法 |
| US8057876B2 (en) * | 2008-02-25 | 2011-11-15 | Abbott Cardiovascular Systems Inc. | Bioabsorbable stent with layers having different degradation rates |
| CN105688276A (zh) | 2008-02-29 | 2016-06-22 | 史密夫和内修有限公司 | 用于生物医学应用的梯度涂层 |
| JP2009247506A (ja) * | 2008-04-03 | 2009-10-29 | Kaneka Corp | ステント |
| US8236046B2 (en) | 2008-06-10 | 2012-08-07 | Boston Scientific Scimed, Inc. | Bioerodible endoprosthesis |
| US8206636B2 (en) | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
| US10898620B2 (en) | 2008-06-20 | 2021-01-26 | Razmodics Llc | Composite stent having multi-axial flexibility and method of manufacture thereof |
| US8206635B2 (en) * | 2008-06-20 | 2012-06-26 | Amaranth Medical Pte. | Stent fabrication via tubular casting processes |
| US8445008B2 (en) | 2008-10-17 | 2013-05-21 | Medtronic, Inc. | Reduction of infection associated with medical device |
| EP2391397A2 (en) * | 2009-02-02 | 2011-12-07 | Medtronic, Inc. | Composite antimicrobial accessory including a membrane layer and a porous layer |
| US9492587B2 (en) * | 2009-04-13 | 2016-11-15 | Abbott Cardiovascular Systems Inc. | Stent made from an ultra high molecular weight bioabsorbable polymer with high fatigue and fracture resistance |
| US8858983B2 (en) | 2009-04-30 | 2014-10-14 | Medtronic, Inc. | Antioxidants and antimicrobial accessories including antioxidants |
| JP5856569B2 (ja) | 2010-02-05 | 2016-02-10 | サイト サイエンシーズ, インコーポレイテッド | 眼内圧を低減するためのデバイスと、それを含むキット |
| US8652505B2 (en) * | 2010-03-04 | 2014-02-18 | Southwest Research Institute | Coating for medical implants |
| WO2011119573A1 (en) | 2010-03-23 | 2011-09-29 | Boston Scientific Scimed, Inc. | Surface treated bioerodible metal endoprostheses |
| US8685433B2 (en) * | 2010-03-31 | 2014-04-01 | Abbott Cardiovascular Systems Inc. | Absorbable coating for implantable device |
| US8911427B2 (en) | 2010-12-28 | 2014-12-16 | Medtronic, Inc. | Therapeutic agent reservoir delivery system |
| JP2014515621A (ja) * | 2011-01-13 | 2014-07-03 | イノビア,リミティド ライアビリティー カンパニー | 腔内薬物アプリケータ及び身体の病変血管を治療する方法 |
| ES2961369T3 (es) | 2012-03-20 | 2024-03-11 | Sight Sciences Inc | Sistemas de entrega ocular |
| US10232090B2 (en) | 2013-08-23 | 2019-03-19 | Southwest Research Institute | Electrophoretically deposited strontium fluoride nanoparticle/polymer coatings for medical implants |
| CN104587534A (zh) * | 2013-10-31 | 2015-05-06 | 先健科技(深圳)有限公司 | 可吸收铁基合金支架 |
| EP2918263B1 (en) * | 2014-03-13 | 2017-05-03 | Sabanci Üniversitesi | Pharmaceutical drug delivery system |
| US10299958B2 (en) | 2015-03-31 | 2019-05-28 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| US11504270B1 (en) | 2019-09-27 | 2022-11-22 | Sight Sciences, Inc. | Ocular delivery systems and methods |
| CN111110413A (zh) * | 2020-03-02 | 2020-05-08 | 南京浩衍鼎业科技技术有限公司 | 一种具有微孔阵列的颅内可降解生物支架及其制备方法 |
| CN112370634B (zh) * | 2020-11-03 | 2023-04-25 | 山东华安生物科技有限公司 | 一种复合管及其制备方法和应用 |
| CN113730042B (zh) * | 2021-09-09 | 2022-10-11 | 北京理工大学 | 具有多级微纳结构的骨科植入体及其制造方法 |
| CN116173381A (zh) * | 2022-12-19 | 2023-05-30 | 上海百心安生物技术股份有限公司 | 一种新型可控制药物释放的药物球囊导管及其应用 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4842867A (en) * | 1986-05-09 | 1989-06-27 | Alza Corporation | Pulsed drug delivery of doxylamine |
| US5021053A (en) * | 1989-07-14 | 1991-06-04 | Alza Corporation | Oral osmotic device with hydrogel driving member |
| US5049138A (en) * | 1989-11-13 | 1991-09-17 | Boston Scientific Corporation | Catheter with dissolvable tip |
| WO1993006792A1 (en) * | 1991-10-04 | 1993-04-15 | Scimed Life Systems, Inc. | Biodegradable drug delivery vascular stent |
| US5260002A (en) * | 1991-12-23 | 1993-11-09 | Vanderbilt University | Method and apparatus for producing uniform polymeric spheres |
| GB9200607D0 (en) * | 1992-01-13 | 1992-03-11 | Ethical Pharma Ltd | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
| US5824048A (en) * | 1993-04-26 | 1998-10-20 | Medtronic, Inc. | Method for delivering a therapeutic substance to a body lumen |
| US5362718A (en) * | 1994-04-18 | 1994-11-08 | American Home Products Corporation | Rapamycin hydroxyesters |
| US5788979A (en) * | 1994-07-22 | 1998-08-04 | Inflow Dynamics Inc. | Biodegradable coating with inhibitory properties for application to biocompatible materials |
| US6020004A (en) * | 1997-04-17 | 2000-02-01 | Amgen Inc. | Biodegradable microparticles for the sustained delivery of therapeutic drugs |
| US6015815A (en) * | 1997-09-26 | 2000-01-18 | Abbott Laboratories | Tetrazole-containing rapamycin analogs with shortened half-lives |
| DK1035834T3 (da) * | 1997-12-05 | 2002-07-08 | Alza Corp | Osmotisk doseringsform omfattende en første og anden coating |
| US6245357B1 (en) * | 1998-03-06 | 2001-06-12 | Alza Corporation | Extended release dosage form |
| US7208010B2 (en) * | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
| US6335029B1 (en) * | 1998-08-28 | 2002-01-01 | Scimed Life Systems, Inc. | Polymeric coatings for controlled delivery of active agents |
| EP1152709B1 (en) * | 1999-02-02 | 2005-01-12 | Wright Medical Technology, Inc. | Controlled release composite |
| US6368658B1 (en) * | 1999-04-19 | 2002-04-09 | Scimed Life Systems, Inc. | Coating medical devices using air suspension |
| US6716444B1 (en) * | 2000-09-28 | 2004-04-06 | Advanced Cardiovascular Systems, Inc. | Barriers for polymer-coated implantable medical devices and methods for making the same |
| AU9486901A (en) * | 2000-09-29 | 2002-04-08 | Cordis Corp | Coated medical devices |
| US6471980B2 (en) * | 2000-12-22 | 2002-10-29 | Avantec Vascular Corporation | Intravascular delivery of mycophenolic acid |
| US7396539B1 (en) * | 2002-06-21 | 2008-07-08 | Advanced Cardiovascular Systems, Inc. | Stent coatings with engineered drug release rate |
| US7232573B1 (en) * | 2002-09-26 | 2007-06-19 | Advanced Cardiovascular Systems, Inc. | Stent coatings containing self-assembled monolayers |
| US7491234B2 (en) * | 2002-12-03 | 2009-02-17 | Boston Scientific Scimed, Inc. | Medical devices for delivery of therapeutic agents |
| US7169404B2 (en) * | 2003-07-30 | 2007-01-30 | Advanced Cardiovasular Systems, Inc. | Biologically absorbable coatings for implantable devices and methods for fabricating the same |
-
2003
- 2003-09-18 US US10/527,414 patent/US20070078513A1/en not_active Abandoned
- 2003-09-18 WO PCT/US2003/030010 patent/WO2004026361A1/en not_active Ceased
- 2003-09-18 AU AU2003275190A patent/AU2003275190A1/en not_active Abandoned
- 2003-09-18 EP EP03759459A patent/EP1539270A1/en not_active Withdrawn
- 2003-09-18 JP JP2004538458A patent/JP2005538809A/ja active Pending
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