JP2005530779A - ベンラファキシンとその誘導体を用いた胃腸または尿生殖器痛障害の治療方法 - Google Patents

ベンラファキシンとその誘導体を用いた胃腸または尿生殖器痛障害の治療方法 Download PDF

Info

Publication number
JP2005530779A
JP2005530779A JP2004505028A JP2004505028A JP2005530779A JP 2005530779 A JP2005530779 A JP 2005530779A JP 2004505028 A JP2004505028 A JP 2004505028A JP 2004505028 A JP2004505028 A JP 2004505028A JP 2005530779 A JP2005530779 A JP 2005530779A
Authority
JP
Japan
Prior art keywords
carbon atoms
alkyl
functional gastrointestinal
hydrogen
gastrointestinal disorder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004505028A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005530779A5 (enExample
Inventor
ロビン・ゲイル・カールスタット
リチャード・ブライアン・リン
マイケル・スコット・バートン
マービン・ダナイルウィッツ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
Wyeth LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC filed Critical Wyeth LLC
Publication of JP2005530779A publication Critical patent/JP2005530779A/ja
Publication of JP2005530779A5 publication Critical patent/JP2005530779A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2004505028A 2002-05-17 2003-05-15 ベンラファキシンとその誘導体を用いた胃腸または尿生殖器痛障害の治療方法 Pending JP2005530779A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38130502P 2002-05-17 2002-05-17
PCT/US2003/015230 WO2003097029A1 (en) 2002-05-17 2003-05-15 Methods of treating gastrointestinal and genitourinary pain disorders using vinlafaxin and derivatives

Publications (2)

Publication Number Publication Date
JP2005530779A true JP2005530779A (ja) 2005-10-13
JP2005530779A5 JP2005530779A5 (enExample) 2006-06-29

Family

ID=29550101

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004505028A Pending JP2005530779A (ja) 2002-05-17 2003-05-15 ベンラファキシンとその誘導体を用いた胃腸または尿生殖器痛障害の治療方法

Country Status (21)

Country Link
US (1) US20040019101A1 (enExample)
EP (1) EP1505960A1 (enExample)
JP (1) JP2005530779A (enExample)
KR (1) KR20050003464A (enExample)
CN (1) CN1652758A (enExample)
AR (1) AR040033A1 (enExample)
AU (1) AU2003232137A1 (enExample)
BR (1) BR0310083A (enExample)
CA (1) CA2485736A1 (enExample)
CR (1) CR7568A (enExample)
EC (1) ECSP045436A (enExample)
IL (1) IL165216A0 (enExample)
MX (1) MXPA04011329A (enExample)
NO (1) NO20044868L (enExample)
NZ (1) NZ548950A (enExample)
RU (1) RU2004136999A (enExample)
SG (1) SG165991A1 (enExample)
TW (1) TW200402289A (enExample)
UA (1) UA81413C2 (enExample)
WO (1) WO2003097029A1 (enExample)
ZA (1) ZA200410157B (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491723B2 (en) * 2003-10-14 2009-02-17 Wyeth Alkanol and cycloalkanol-amine derivatives and methods of their use
US7419980B2 (en) * 2003-10-14 2008-09-02 Wyeth Fused-aryl and heteroaryl derivatives and methods of their use
US7365076B2 (en) 2003-10-14 2008-04-29 Wyeth Substituted aryl cycloalkanol derivatives and methods of their use
US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
US7524846B2 (en) * 2003-10-14 2009-04-28 Wyeth Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use
US7402698B2 (en) * 2003-10-14 2008-07-22 Wyeth Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
US7531543B2 (en) * 2003-10-14 2009-05-12 Wyeth Phenylpiperazine cycloalkanol derivatives and methods of their use
US20060148781A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder in a non-human mammal
US20050113365A1 (en) * 2003-11-10 2005-05-26 Sir Isaac Newton Enterprises Llc Method and medicine for treating gastrointestinal disorder including irritable bowel syndrome
US20060148783A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US20070142367A1 (en) * 2003-11-10 2007-06-21 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US20060148782A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating a mammal presenting urinary incontinence, urinary urgency, or both
US7820690B2 (en) * 2004-03-19 2010-10-26 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
US7517899B2 (en) * 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
US7414052B2 (en) * 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
GB201007032D0 (en) * 2010-04-27 2010-06-09 Dormer Tools Ltd Twist drill for advanced materials
CN102095461B (zh) * 2011-01-18 2012-07-18 姚贤卿 复合型干度质量流量仪及干度标定测量方法
RU2740750C1 (ru) * 2020-03-27 2021-01-20 Аллан Герович Бениашвили Средство для лечения функциональных заболеваний желудочно-кишечного тракта

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
US5990159A (en) * 1996-02-15 1999-11-23 Janssen Pharmaceutica, N.V. Use of 5HT4 receptor antagonists for overcoming gastrointestinal effects of serotonin reuptake inhibitors
US6579899B1 (en) * 1998-07-16 2003-06-17 Massachusetts Institute Of Technology Composition for treatment of stress
JP2002530341A (ja) * 1998-11-23 2002-09-17 セプラコール， インク． デスメチルオランザピン組成物及び方法
CA2352611A1 (en) * 1998-11-23 2000-06-02 Sepracor Inc. 2-hydroxymethylolanzapine compositions and methods
CA2351719A1 (en) * 1998-11-23 2000-06-02 Sepracor Inc. Pharmaceutical compositions containing olanzapine-n-oxide
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
GB2355191A (en) * 1999-10-12 2001-04-18 Laxdale Ltd Combination formulations for fatigue, head injury and strokes
MXPA04011529A (es) * 2002-04-24 2005-08-15 Cypress Bioscience Inc Prevencion y tratamiento de trastornos somaticos funcionales, incluyendo trastornos relacionados con la tension.
NZ537142A (en) * 2002-06-10 2008-01-31 Wyeth Corp Novel formate salt of O-desmethyl-venlafaxine

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN5004016768, ＬＹＤＩＡＲＤ Ｒ．Ｂ．, ＪＯＵＲＮＡＬ ＯＦ ＣＬＩＮＩＣＡＬ ＰＳＹＣＨＩＡＴＲＹ, 1997, Ｖ５８ ＳＵＰＰＬ．３, Ｐ５１−６１ *
JPN5004016770, ＯＬＤＥＮ Ｋ．Ｗ．, ＭＥＤＩＣＡＬ ＣＬＩＮＩＣＳ ＯＦ ＮＯＲＴＨ ＡＭＥＲＩＣＡ, 2000, Ｖ８４ Ｎ５, Ｐ１３１３−１３２７ *

Also Published As

Publication number Publication date
MXPA04011329A (es) 2005-02-14
ECSP045436A (es) 2005-01-03
CN1652758A (zh) 2005-08-10
IL165216A0 (en) 2005-12-18
BR0310083A (pt) 2005-02-15
US20040019101A1 (en) 2004-01-29
AR040033A1 (es) 2005-03-09
TW200402289A (en) 2004-02-16
NO20044868L (no) 2004-12-08
ZA200410157B (en) 2006-05-31
WO2003097029A1 (en) 2003-11-27
CA2485736A1 (en) 2003-11-27
AU2003232137A1 (en) 2003-12-02
EP1505960A1 (en) 2005-02-16
RU2004136999A (ru) 2006-06-10
KR20050003464A (ko) 2005-01-10
SG165991A1 (en) 2010-11-29
CR7568A (es) 2005-02-08
NZ548950A (en) 2008-01-31
UA81413C2 (en) 2008-01-10

Similar Documents

Publication Publication Date Title
JP2005530779A (ja) ベンラファキシンとその誘導体を用いた胃腸または尿生殖器痛障害の治療方法
ES2304041T3 (es) Nuevos tratamientos que utilizan derivados de fenetilamina.
JP2009527525A (ja) 尿失禁治療用のベンゾイミダゾロン誘導体
JPS61277620A (ja) 排尿困難治療剤
JP2002523366A (ja) ドーパミン再取込みインヒビターを含有する組成物及びその使用方法
TW200815010A (en) CGRP antagonists
JPH08231387A (ja) うつ病でない雌性の哺乳動物における視床下部性無月経を処置するための医薬組成物
US20100160294A1 (en) Tolerability of mirtazapine and a second active by using them in combination
ES2260195T3 (es) Metodos de producir (r)-y (s)-didesmetil-sibutramina opticamente pura.
PL204075B1 (pl) Zastosowanie kompozycji farmaceutycznej zawierającej metoklopramid oraz tramadol do wytwarzania leku
BRPI0713733A2 (pt) métodos para diminuir os sintomas de depressão e para tratar uma ou mais condições psicológicas, composição farmacêutica e kit
BRPI0713728A2 (pt) método para promover perda de peso ou faciliatr a manutenção de um peso estável, composição farmacêutica, e, kit
JP6067022B2 (ja) 情動障害の予防又は治療に用いるためのｎ−置換ベンゼンプロパンアミド又はベンゼンプロペンアミド
US20080176951A1 (en) Methods of treating gastrointestinary and genitourinary pain disorders
RU2455981C2 (ru) Лечение ожирения антагонистами мускаринового рецептора м1
EP0667150B1 (en) Venlafaxine and its analogues for inducing cognition enhancement
JP2610735B2 (ja) 抗鬱剤および抗ストレス剤組成物
JPWO2005102313A1 (ja) 慢性副鼻腔炎の予防および／または治療剤
JP5807767B2 (ja) 便秘症の予防又は治療薬
JP2008239540A (ja) 子宮内膜症の予防および／または治療剤
AU2009292498A1 (en) Novel pharmaceutical composition for treatment of nociceptive pain
AU2007202664A1 (en) 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno(2,3-D) pyrimidine in the treatment of functional bowel disorder
MX2011013993A (es) Combinacion farmaceutica.

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060511

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060511

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20091013

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20100506