BR0310083A - Métodos de tratar distúrbios de dor gastrointestinal e genitourinária empregando-se venlafaxina e derivados - Google Patents

Métodos de tratar distúrbios de dor gastrointestinal e genitourinária empregando-se venlafaxina e derivados

Info

Publication number
BR0310083A
BR0310083A BR0310083-9A BR0310083A BR0310083A BR 0310083 A BR0310083 A BR 0310083A BR 0310083 A BR0310083 A BR 0310083A BR 0310083 A BR0310083 A BR 0310083A
Authority
BR
Brazil
Prior art keywords
alkyl
hydrogen
derivatives
methods
genitourinary
Prior art date
Application number
BR0310083-9A
Other languages
English (en)
Inventor
Robyn Gail Karlstadt
Richard Brian Lynn
Michael Scott Burton
Mervyn Danilewitz
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of BR0310083A publication Critical patent/BR0310083A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect

Abstract

"MéTODOS DE TRATAR DISTúRBIOS DE DOR GASTROINTESTINAL E GENITOURINáRIA EMPREGANDO-SE VENLAFAXINA E DERIVADOS". A presente invenção refere-se a um método para tratar os distúrbios geniturinários e gastrointestinais funcionais em um mamífero administrando-se ao mamífero uma quantidade eficaz de hidroxicicloalcano fenetilamina da seguinte fórmula estrutural (I) na qual A é uma porção da fórmula (II) onde a linha pontilhada representa a insaturação opcional; R~ 1~ é hidrogênio ou alquila; R~ 2~ é alquila; R~ 4~ é hidrogênio, alquila, formila, ou alcanol; R~ 5~ e R~ 6~ são, independentemente, hidrogênio, hidroxila, alquila, alcóxi, alcanoilóxi, ciano, nitro, alquilmercapto, amino, alquilamino, dialquilamino, alcamido, halo, trifluorometila, ou tomados juntos, metileno dióxi; R~ 7~ é hidrogênio ou alquila; e n é 0, 1, 2, 3 ou 4, ou um sal farmaceuticamente aceitável deste.
BR0310083-9A 2002-05-17 2003-05-15 Métodos de tratar distúrbios de dor gastrointestinal e genitourinária empregando-se venlafaxina e derivados BR0310083A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38130502P 2002-05-17 2002-05-17
PCT/US2003/015230 WO2003097029A1 (en) 2002-05-17 2003-05-15 Methods of treating gastrointestinal and genitourinary pain disorders using vinlafaxin and derivatives

Publications (1)

Publication Number Publication Date
BR0310083A true BR0310083A (pt) 2005-02-15

Family

ID=29550101

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0310083-9A BR0310083A (pt) 2002-05-17 2003-05-15 Métodos de tratar distúrbios de dor gastrointestinal e genitourinária empregando-se venlafaxina e derivados

Country Status (21)

Country Link
US (1) US20040019101A1 (pt)
EP (1) EP1505960A1 (pt)
JP (1) JP2005530779A (pt)
KR (1) KR20050003464A (pt)
CN (1) CN1652758A (pt)
AR (1) AR040033A1 (pt)
AU (1) AU2003232137A1 (pt)
BR (1) BR0310083A (pt)
CA (1) CA2485736A1 (pt)
CR (1) CR7568A (pt)
EC (1) ECSP045436A (pt)
IL (1) IL165216A0 (pt)
MX (1) MXPA04011329A (pt)
NO (1) NO20044868L (pt)
NZ (1) NZ548950A (pt)
RU (1) RU2004136999A (pt)
SG (1) SG165991A1 (pt)
TW (1) TW200402289A (pt)
UA (1) UA81413C2 (pt)
WO (1) WO2003097029A1 (pt)
ZA (1) ZA200410157B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402698B2 (en) * 2003-10-14 2008-07-22 Wyeth Secondary amino-and cycloamino-cycloalkanol derivatives and methods of their use
US7524846B2 (en) * 2003-10-14 2009-04-28 Wyeth Arylalkyl- and cycloalkylalkyl-piperazine derivatives and methods of their use
US7419980B2 (en) * 2003-10-14 2008-09-02 Wyeth Fused-aryl and heteroaryl derivatives and methods of their use
US7491723B2 (en) * 2003-10-14 2009-02-17 Wyeth Alkanol and cycloalkanol-amine derivatives and methods of their use
US7531543B2 (en) * 2003-10-14 2009-05-12 Wyeth Phenylpiperazine cycloalkanol derivatives and methods of their use
US7365076B2 (en) * 2003-10-14 2008-04-29 Wyeth Substituted aryl cycloalkanol derivatives and methods of their use
US7550485B2 (en) * 2003-10-14 2009-06-23 Wyeth Substituted N-heterocycle derivatives and methods of their use
US20060148783A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US20050113365A1 (en) * 2003-11-10 2005-05-26 Sir Isaac Newton Enterprises Llc Method and medicine for treating gastrointestinal disorder including irritable bowel syndrome
US20060148782A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating a mammal presenting urinary incontinence, urinary urgency, or both
US20060148781A1 (en) * 2003-11-10 2006-07-06 Lundeen James E Method and medicine for treating gastrointestinal disorder in a non-human mammal
US20070142367A1 (en) * 2003-11-10 2007-06-21 Lundeen James E Method and medicine for treating gastrointestinal disorder including fecal incontinence
US7820690B2 (en) * 2004-03-19 2010-10-26 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting a non-digestive tract derived abdominal disorder associated with pain using a 5-HT, receptor antagonist
US7414052B2 (en) * 2004-03-30 2008-08-19 Wyeth Phenylaminopropanol derivatives and methods of their use
US7517899B2 (en) * 2004-03-30 2009-04-14 Wyeth Phenylaminopropanol derivatives and methods of their use
US20080081067A1 (en) * 2006-10-03 2008-04-03 Gupta Manishkumar Sustained release pharmaceutical compositions of venlafaxine and process for preparation thereof
GB201007032D0 (en) * 2010-04-27 2010-06-09 Dormer Tools Ltd Twist drill for advanced materials
CN102095461B (zh) * 2011-01-18 2012-07-18 姚贤卿 复合型干度质量流量仪及干度标定测量方法
RU2740750C1 (ru) * 2020-03-27 2021-01-20 Аллан Герович Бениашвили Средство для лечения функциональных заболеваний желудочно-кишечного тракта

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535186A (en) * 1983-04-19 1985-08-13 American Home Products Corporation 2-Phenyl-2-(1-hydroxycycloalkyl or 1-hydroxycycloalk-2-enyl)ethylamine derivatives
JP2000516198A (ja) * 1996-02-15 2000-12-05 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ セロトニンの再取り込み阻害剤の胃腸に対する作用を克服するための５ｈｔ４レセプター拮抗剤の使用
US6579899B1 (en) * 1998-07-16 2003-06-17 Massachusetts Institute Of Technology Composition for treatment of stress
ES2237188T3 (es) * 1998-11-23 2005-07-16 Sepracor Inc. Composiciones de desmetilolanzapina y metodos.
WO2000030648A1 (en) * 1998-11-23 2000-06-02 Sepracor Inc. 2-hydroxymethylolanzapine compositions and methods
ATE253364T1 (de) * 1998-11-23 2003-11-15 Sepracor Inc Olanzapin-n-oxide enthaltende pharmaceutische zusammensetzungen
US6294192B1 (en) * 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
GB2355191A (en) * 1999-10-12 2001-04-18 Laxdale Ltd Combination formulations for fatigue, head injury and strokes
EP1499309A4 (en) * 2002-04-24 2008-05-28 Cypress Bioscience Inc PREVENTION AND TREATMENT OF FUNCTIONAL SOMATIC DISEASES, INCLUDING STRESS-BASED DISEASES
MXPA04012347A (es) * 2002-06-10 2005-02-25 Wyeth Corp Nueva sal formiato de o-desmetilvenlafaxina.

Also Published As

Publication number Publication date
AU2003232137A1 (en) 2003-12-02
EP1505960A1 (en) 2005-02-16
IL165216A0 (en) 2005-12-18
NZ548950A (en) 2008-01-31
AR040033A1 (es) 2005-03-09
TW200402289A (en) 2004-02-16
ZA200410157B (en) 2006-05-31
US20040019101A1 (en) 2004-01-29
CN1652758A (zh) 2005-08-10
MXPA04011329A (es) 2005-02-14
CA2485736A1 (en) 2003-11-27
WO2003097029A1 (en) 2003-11-27
SG165991A1 (en) 2010-11-29
JP2005530779A (ja) 2005-10-13
ECSP045436A (es) 2005-01-03
NO20044868L (no) 2004-12-08
CR7568A (es) 2005-02-08
RU2004136999A (ru) 2006-06-10
KR20050003464A (ko) 2005-01-10
UA81413C2 (en) 2008-01-10

Similar Documents

Publication Publication Date Title
BR0310083A (pt) Métodos de tratar distúrbios de dor gastrointestinal e genitourinária empregando-se venlafaxina e derivados
NZ280744A (en) Treatment of hypothalamic amenorrhea in non-depressed female mammals by administering an hydroxycycloalkanephenethylamine derivative
PT639374E (pt) Novos tratamentos utilizado derivados fenetilo
DK1169060T3 (da) Natriumkanalblokkerpræparater og anvendelse deraf
ES2295609T3 (es) Derivados de tiadiazolilpiperazina utiles para tratar o prevenir un dolor.
MY126489A (en) Phenoxyacetic acid derivatives and medicinal compositions containing the same
BR0213040A (pt) Composto, processo para preparar um composto, e, método de tratar doenças
NO20050145L (no) Spirocykliske piperidiner som MCH1-antagonister og anvendelser derav
NO20015931L (no) Farmasöytiske formuleringer og fremgangsmåter som omfatter intranasal morfin
BRPI0410316A (pt) composto, composição farmacêutica, uso dos compostos, e, método de tratamento de distúrbios mediados por vr1 e para o tratamento de distúrbios de dores
BR9911887A (pt) Método para o tratamento da insÈnia
BRPI0414011A (pt) naftalencarboxamidas e seus derivados úteis como novos agentes antiangiogênicos
DK0699439T3 (da) Behandling af sygdomme forårsaget af talgkirtellidelser med acyl-CoA-cholesterolacyltransferaseinhibitorer
BR9909138A (pt) Combinação para o tratamento de dependência de álcool e drogas contendo um antagonista de opióide e um modulador de complexo receptor de nmda
BR0214672A (pt) Inibidores de fosfolipase citosólica a2
BR0008443A (pt) Inibidores de aminotransferaseaminoácido-dependente de cadeia ramificada e seuuso no tratamento da retinopatia diabética
DK0986393T3 (da) Anvendelse af et nitroxid eller et prodrug heraf ved profylaktisk og terapeutisk behandling af cancer
WO2001080813A3 (en) Methods for preventing and treating alopecia induced by chemotherapy or radiotherapy
BR0213237A (pt) Derivados de ácido [[2-(amino-3,4-dioxo-1-ciclobuten-1-il) amino] alquila] para o tratamento de dor
EP1043314A4 (en) NEW DIHYDROPYRIDINE DERIVATIVE
BR0010961A (pt) Composto, composição farmacêutica, e, métodos para tratar epilepsia, ataques de tontura, hipocinésia, e distúrbios cranianos, distúrbios neurodegenerativos, depressão, ansiedade, pânico, dor, distúrbios neuropatológicos e distúrbios do sono
MXPA01007952A (es) Formulaciones a base de l-arginina para tratar enfermedades, y metodos para usarlas.
BR0305070A (pt) Uso de derivado amida de ge 2270 fator a3 para tratamento da acne
BR0316751A (pt) Análogos de gabapentina para fibromialgia e outros distúrbios relacionados
BR0209995A (pt) Aril-8-aza-biciclo[3.2.1]octanos para o tratamento de depressão

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE 8A. ANUIDADES(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: NAO APRESENTADA A GUIA DE CUMPRIMENTO DE EXIGENCIA. REFERENTE AS 8A E 9A ANUIDADES.