JP2005521383A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2005521383A5 JP2005521383A5 JP2003545688A JP2003545688A JP2005521383A5 JP 2005521383 A5 JP2005521383 A5 JP 2005521383A5 JP 2003545688 A JP2003545688 A JP 2003545688A JP 2003545688 A JP2003545688 A JP 2003545688A JP 2005521383 A5 JP2005521383 A5 JP 2005521383A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- acid sequence
- seq
- peptide
- peptide represented
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 66
- 125000003275 alpha amino acid group Chemical group 0.000 claims 43
- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 210000003491 skin Anatomy 0.000 claims 13
- 210000002784 stomach Anatomy 0.000 claims 8
- 210000001519 tissue Anatomy 0.000 claims 8
- 201000010099 disease Diseases 0.000 claims 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 6
- 210000000481 breast Anatomy 0.000 claims 5
- 210000002808 connective tissue Anatomy 0.000 claims 5
- 210000005069 ears Anatomy 0.000 claims 5
- 210000001508 eye Anatomy 0.000 claims 5
- 210000000214 mouth Anatomy 0.000 claims 5
- 210000003205 muscle Anatomy 0.000 claims 5
- 210000001331 nose Anatomy 0.000 claims 5
- 210000000056 organ Anatomy 0.000 claims 5
- 210000002741 palatine tonsil Anatomy 0.000 claims 5
- 210000003800 pharynx Anatomy 0.000 claims 5
- 210000002307 prostate Anatomy 0.000 claims 5
- 206010062767 Hypophysitis Diseases 0.000 claims 4
- 210000004100 adrenal gland Anatomy 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 210000000988 bone and bone Anatomy 0.000 claims 4
- 210000004556 brain Anatomy 0.000 claims 4
- 210000001072 colon Anatomy 0.000 claims 4
- 210000003238 esophagus Anatomy 0.000 claims 4
- 210000000232 gallbladder Anatomy 0.000 claims 4
- 210000002216 heart Anatomy 0.000 claims 4
- 210000000936 intestine Anatomy 0.000 claims 4
- 210000003734 kidney Anatomy 0.000 claims 4
- 210000004185 liver Anatomy 0.000 claims 4
- 210000004072 lung Anatomy 0.000 claims 4
- 210000001165 lymph node Anatomy 0.000 claims 4
- 210000004324 lymphatic system Anatomy 0.000 claims 4
- 210000001672 ovary Anatomy 0.000 claims 4
- 210000000496 pancreas Anatomy 0.000 claims 4
- 210000002990 parathyroid gland Anatomy 0.000 claims 4
- 210000003635 pituitary gland Anatomy 0.000 claims 4
- 210000000664 rectum Anatomy 0.000 claims 4
- 230000001850 reproductive effect Effects 0.000 claims 4
- 210000003079 salivary gland Anatomy 0.000 claims 4
- 210000000278 spinal cord Anatomy 0.000 claims 4
- 210000000952 spleen Anatomy 0.000 claims 4
- 210000001550 testis Anatomy 0.000 claims 4
- 210000001685 thyroid gland Anatomy 0.000 claims 4
- 210000003932 urinary bladder Anatomy 0.000 claims 4
- 210000004291 uterus Anatomy 0.000 claims 4
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 3
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 3
- 230000027455 binding Effects 0.000 claims 3
- 210000004027 cell Anatomy 0.000 claims 3
- 102000004196 processed proteins & peptides Human genes 0.000 claims 3
- 238000011282 treatment Methods 0.000 claims 3
- 206010020880 Hypertrophy Diseases 0.000 claims 2
- 208000026350 Inborn Genetic disease Diseases 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000031481 Pathologic Constriction Diseases 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 210000001367 artery Anatomy 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 206010015037 epilepsy Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 206010020718 hyperplasia Diseases 0.000 claims 2
- 230000036244 malformation Effects 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 208000037804 stenosis Diseases 0.000 claims 2
- 230000036262 stenosis Effects 0.000 claims 2
- 238000002054 transplantation Methods 0.000 claims 2
- 208000019553 vascular disease Diseases 0.000 claims 2
- 206010003210 Arteriosclerosis Diseases 0.000 claims 1
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000023275 Autoimmune disease Diseases 0.000 claims 1
- 206010010356 Congenital anomaly Diseases 0.000 claims 1
- 206010012335 Dependence Diseases 0.000 claims 1
- 201000004624 Dermatitis Diseases 0.000 claims 1
- 208000017701 Endocrine disease Diseases 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 206010016654 Fibrosis Diseases 0.000 claims 1
- 208000028782 Hereditary disease Diseases 0.000 claims 1
- 208000002720 Malnutrition Diseases 0.000 claims 1
- 241000124008 Mammalia Species 0.000 claims 1
- 208000024556 Mendelian disease Diseases 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 208000012868 Overgrowth Diseases 0.000 claims 1
- 201000004681 Psoriasis Diseases 0.000 claims 1
- 206010046996 Varicose vein Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 238000002679 ablation Methods 0.000 claims 1
- 206010002022 amyloidosis Diseases 0.000 claims 1
- 208000011775 arteriosclerosis disease Diseases 0.000 claims 1
- 208000010668 atopic eczema Diseases 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- 201000011510 cancer Diseases 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 238000000315 cryotherapy Methods 0.000 claims 1
- 230000007812 deficiency Effects 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 208000016097 disease of metabolism Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 208000030172 endocrine system disease Diseases 0.000 claims 1
- 230000007613 environmental effect Effects 0.000 claims 1
- 230000004761 fibrosis Effects 0.000 claims 1
- 238000001415 gene therapy Methods 0.000 claims 1
- 208000016361 genetic disease Diseases 0.000 claims 1
- 210000004209 hair Anatomy 0.000 claims 1
- 238000009169 immunotherapy Methods 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 208000027866 inflammatory disease Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 208000014674 injury Diseases 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 238000007913 intrathecal administration Methods 0.000 claims 1
- 230000002601 intratumoral effect Effects 0.000 claims 1
- 238000001990 intravenous administration Methods 0.000 claims 1
- 238000002647 laser therapy Methods 0.000 claims 1
- 210000003563 lymphoid tissue Anatomy 0.000 claims 1
- 208000030159 metabolic disease Diseases 0.000 claims 1
- 230000009149 molecular binding Effects 0.000 claims 1
- 235000018343 nutrient deficiency Nutrition 0.000 claims 1
- 230000003071 parasitic effect Effects 0.000 claims 1
- 238000001126 phototherapy Methods 0.000 claims 1
- 208000037803 restenosis Diseases 0.000 claims 1
- 208000017520 skin disease Diseases 0.000 claims 1
- 238000007920 subcutaneous administration Methods 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
- 230000000472 traumatic effect Effects 0.000 claims 1
- 238000002255 vaccination Methods 0.000 claims 1
- 208000027185 varicose disease Diseases 0.000 claims 1
- 230000003612 virological effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33147701P | 2001-11-16 | 2001-11-16 | |
| US60/331,477 | 2001-11-16 | ||
| PCT/CA2002/001757 WO2003044053A2 (en) | 2001-11-16 | 2002-11-18 | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011011764A Division JP5357196B2 (ja) | 2001-11-16 | 2011-01-24 | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005521383A JP2005521383A (ja) | 2005-07-21 |
| JP2005521383A5 true JP2005521383A5 (enExample) | 2006-01-12 |
| JP4717349B2 JP4717349B2 (ja) | 2011-07-06 |
Family
ID=23294135
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003545688A Expired - Fee Related JP4717349B2 (ja) | 2001-11-16 | 2002-11-18 | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
| JP2011011764A Expired - Fee Related JP5357196B2 (ja) | 2001-11-16 | 2011-01-24 | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011011764A Expired - Fee Related JP5357196B2 (ja) | 2001-11-16 | 2011-01-24 | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
Country Status (22)
| Country | Link |
|---|---|
| US (5) | US7317077B2 (enExample) |
| EP (1) | EP1442058B1 (enExample) |
| JP (2) | JP4717349B2 (enExample) |
| KR (4) | KR20140044399A (enExample) |
| CN (1) | CN100509846C (enExample) |
| AT (1) | ATE333467T1 (enExample) |
| AU (1) | AU2002342463B2 (enExample) |
| BR (1) | BRPI0213786B8 (enExample) |
| CA (1) | CA2467053C (enExample) |
| CY (1) | CY1107578T1 (enExample) |
| DE (1) | DE60213274T2 (enExample) |
| DK (1) | DK1442058T3 (enExample) |
| EA (1) | EA007203B1 (enExample) |
| ES (1) | ES2269775T3 (enExample) |
| IL (2) | IL161591A0 (enExample) |
| MX (1) | MXPA04004489A (enExample) |
| NO (1) | NO332842B1 (enExample) |
| NZ (1) | NZ532721A (enExample) |
| PL (1) | PL207591B1 (enExample) |
| PT (1) | PT1442058E (enExample) |
| WO (1) | WO2003044053A2 (enExample) |
| ZA (1) | ZA200403624B (enExample) |
Families Citing this family (101)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7317077B2 (en) * | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| ES2564694T3 (es) | 2003-09-12 | 2016-03-28 | Vessix Vascular, Inc. | Sistema de remodelación y / o ablación excéntrica seleccionable de material ateroesclerótico |
| US20090232866A1 (en) * | 2003-10-07 | 2009-09-17 | Mariann Pavone-Gyongyosi | Oligopeptides as coating material for medical products |
| WO2005075647A1 (en) * | 2004-02-06 | 2005-08-18 | Nymox Corporation | Humanized antibody |
| US9713730B2 (en) | 2004-09-10 | 2017-07-25 | Boston Scientific Scimed, Inc. | Apparatus and method for treatment of in-stent restenosis |
| US8396548B2 (en) | 2008-11-14 | 2013-03-12 | Vessix Vascular, Inc. | Selective drug delivery in a lumen |
| CN100427502C (zh) * | 2005-06-09 | 2008-10-22 | 南京大学 | 抗肿瘤寡肽及其制备方法和应用 |
| CA2628271A1 (en) * | 2005-11-02 | 2007-05-10 | Sure International Ventures B.V. | Compositions and methods for cell killing |
| PL1994152T3 (pl) * | 2006-02-28 | 2013-05-31 | Nymox Corp | Peptydy skuteczne w leczeniu nowotworów i innych stanów wymagających usunięcia lub zniszczenia komórek |
| MX2008011570A (es) * | 2006-03-10 | 2008-09-23 | Nymox Corp | Metodo para prevenir o reducir el riesgo o incidencia de cancer usando peptidos basados en proteina de hebra neural. |
| US8019435B2 (en) | 2006-05-02 | 2011-09-13 | Boston Scientific Scimed, Inc. | Control of arterial smooth muscle tone |
| US20080027005A1 (en) * | 2006-07-31 | 2008-01-31 | Paul Averback | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
| EP2076193A4 (en) | 2006-10-18 | 2010-02-03 | Minnow Medical Inc | MATCHED RF-ENERGY AND ELECTRO-TISSUE CHARACTERIZATION FOR THE SELECTIVE TREATMENT OF TARGET TISSUE |
| ES2560006T3 (es) | 2006-10-18 | 2016-02-17 | Vessix Vascular, Inc. | Inducción de efectos de temperatura deseables sobre tejido corporal |
| WO2008049087A2 (en) | 2006-10-18 | 2008-04-24 | Minnow Medical, Inc. | System for inducing desirable temperature effects on body tissue |
| KR20110104504A (ko) | 2008-11-17 | 2011-09-22 | 미노우 메디컬, 인코포레이티드 | 조직 토폴로지의 지식 여하에 따른 에너지의 선택적 축적 |
| JP5625043B2 (ja) * | 2009-04-13 | 2014-11-12 | ザ・フェインスタイン・インスティチュート・フォー・メディカル・リサーチThe Feinstein Institute for Medical Research | 低温誘導性rna結合タンパク質(cirp)を阻害することによる炎症性疾患の治療 |
| CN103068330B (zh) | 2010-04-09 | 2016-06-29 | Vessix血管股份有限公司 | 用于治疗组织的功率发生和控制装置 |
| US9192790B2 (en) | 2010-04-14 | 2015-11-24 | Boston Scientific Scimed, Inc. | Focused ultrasonic renal denervation |
| US8473067B2 (en) | 2010-06-11 | 2013-06-25 | Boston Scientific Scimed, Inc. | Renal denervation and stimulation employing wireless vascular energy transfer arrangement |
| US9358365B2 (en) | 2010-07-30 | 2016-06-07 | Boston Scientific Scimed, Inc. | Precision electrode movement control for renal nerve ablation |
| US9408661B2 (en) | 2010-07-30 | 2016-08-09 | Patrick A. Haverkost | RF electrodes on multiple flexible wires for renal nerve ablation |
| US9084609B2 (en) | 2010-07-30 | 2015-07-21 | Boston Scientific Scime, Inc. | Spiral balloon catheter for renal nerve ablation |
| US9463062B2 (en) | 2010-07-30 | 2016-10-11 | Boston Scientific Scimed, Inc. | Cooled conductive balloon RF catheter for renal nerve ablation |
| US9155589B2 (en) | 2010-07-30 | 2015-10-13 | Boston Scientific Scimed, Inc. | Sequential activation RF electrode set for renal nerve ablation |
| US8974451B2 (en) | 2010-10-25 | 2015-03-10 | Boston Scientific Scimed, Inc. | Renal nerve ablation using conductive fluid jet and RF energy |
| US9220558B2 (en) | 2010-10-27 | 2015-12-29 | Boston Scientific Scimed, Inc. | RF renal denervation catheter with multiple independent electrodes |
| US9028485B2 (en) | 2010-11-15 | 2015-05-12 | Boston Scientific Scimed, Inc. | Self-expanding cooling electrode for renal nerve ablation |
| US9668811B2 (en) | 2010-11-16 | 2017-06-06 | Boston Scientific Scimed, Inc. | Minimally invasive access for renal nerve ablation |
| US9089350B2 (en) | 2010-11-16 | 2015-07-28 | Boston Scientific Scimed, Inc. | Renal denervation catheter with RF electrode and integral contrast dye injection arrangement |
| US9326751B2 (en) | 2010-11-17 | 2016-05-03 | Boston Scientific Scimed, Inc. | Catheter guidance of external energy for renal denervation |
| US9060761B2 (en) | 2010-11-18 | 2015-06-23 | Boston Scientific Scime, Inc. | Catheter-focused magnetic field induced renal nerve ablation |
| US9023034B2 (en) | 2010-11-22 | 2015-05-05 | Boston Scientific Scimed, Inc. | Renal ablation electrode with force-activatable conduction apparatus |
| US9192435B2 (en) | 2010-11-22 | 2015-11-24 | Boston Scientific Scimed, Inc. | Renal denervation catheter with cooled RF electrode |
| US20120157993A1 (en) | 2010-12-15 | 2012-06-21 | Jenson Mark L | Bipolar Off-Wall Electrode Device for Renal Nerve Ablation |
| WO2012100095A1 (en) | 2011-01-19 | 2012-07-26 | Boston Scientific Scimed, Inc. | Guide-compatible large-electrode catheter for renal nerve ablation with reduced arterial injury |
| WO2013013156A2 (en) | 2011-07-20 | 2013-01-24 | Boston Scientific Scimed, Inc. | Percutaneous devices and methods to visualize, target and ablate nerves |
| EP2734264B1 (en) | 2011-07-22 | 2018-11-21 | Boston Scientific Scimed, Inc. | Nerve modulation system with a nerve modulation element positionable in a helical guide |
| WO2013055826A1 (en) | 2011-10-10 | 2013-04-18 | Boston Scientific Scimed, Inc. | Medical devices including ablation electrodes |
| US9420955B2 (en) | 2011-10-11 | 2016-08-23 | Boston Scientific Scimed, Inc. | Intravascular temperature monitoring system and method |
| EP2765940B1 (en) | 2011-10-11 | 2015-08-26 | Boston Scientific Scimed, Inc. | Off-wall electrode device for nerve modulation |
| US9364284B2 (en) | 2011-10-12 | 2016-06-14 | Boston Scientific Scimed, Inc. | Method of making an off-wall spacer cage |
| EP2768568B1 (en) | 2011-10-18 | 2020-05-06 | Boston Scientific Scimed, Inc. | Integrated crossing balloon catheter |
| EP2768563B1 (en) | 2011-10-18 | 2016-11-09 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| US8951251B2 (en) | 2011-11-08 | 2015-02-10 | Boston Scientific Scimed, Inc. | Ostial renal nerve ablation |
| US9119600B2 (en) | 2011-11-15 | 2015-09-01 | Boston Scientific Scimed, Inc. | Device and methods for renal nerve modulation monitoring |
| US9119632B2 (en) | 2011-11-21 | 2015-09-01 | Boston Scientific Scimed, Inc. | Deflectable renal nerve ablation catheter |
| US9265969B2 (en) | 2011-12-21 | 2016-02-23 | Cardiac Pacemakers, Inc. | Methods for modulating cell function |
| AU2012358143B2 (en) | 2011-12-23 | 2015-06-11 | Boston Scientific Scimed, Inc. | Expandable balloon or an electrode pad with a heat sensing device |
| EP2797534A1 (en) | 2011-12-28 | 2014-11-05 | Boston Scientific Scimed, Inc. | Device and methods for nerve modulation using a novel ablation catheter with polymeric ablative elements |
| US9050106B2 (en) | 2011-12-29 | 2015-06-09 | Boston Scientific Scimed, Inc. | Off-wall electrode device and methods for nerve modulation |
| WO2013169927A1 (en) | 2012-05-08 | 2013-11-14 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices |
| CN104540465A (zh) | 2012-08-24 | 2015-04-22 | 波士顿科学西美德公司 | 带有含单独微孔隙区域的球囊的血管内导管 |
| US9173696B2 (en) | 2012-09-17 | 2015-11-03 | Boston Scientific Scimed, Inc. | Self-positioning electrode system and method for renal nerve modulation |
| US10549127B2 (en) | 2012-09-21 | 2020-02-04 | Boston Scientific Scimed, Inc. | Self-cooling ultrasound ablation catheter |
| WO2014047411A1 (en) | 2012-09-21 | 2014-03-27 | Boston Scientific Scimed, Inc. | System for nerve modulation and innocuous thermal gradient nerve block |
| EP2906135A2 (en) | 2012-10-10 | 2015-08-19 | Boston Scientific Scimed, Inc. | Renal nerve modulation devices and methods |
| WO2014143571A1 (en) | 2013-03-11 | 2014-09-18 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
| US9956033B2 (en) | 2013-03-11 | 2018-05-01 | Boston Scientific Scimed, Inc. | Medical devices for modulating nerves |
| US9808311B2 (en) | 2013-03-13 | 2017-11-07 | Boston Scientific Scimed, Inc. | Deflectable medical devices |
| WO2014149690A2 (en) | 2013-03-15 | 2014-09-25 | Boston Scientific Scimed, Inc. | Medical devices and methods for treatment of hypertension that utilize impedance compensation |
| US9827039B2 (en) | 2013-03-15 | 2017-11-28 | Boston Scientific Scimed, Inc. | Methods and apparatuses for remodeling tissue of or adjacent to a body passage |
| US10265122B2 (en) | 2013-03-15 | 2019-04-23 | Boston Scientific Scimed, Inc. | Nerve ablation devices and related methods of use |
| US9943365B2 (en) | 2013-06-21 | 2018-04-17 | Boston Scientific Scimed, Inc. | Renal denervation balloon catheter with ride along electrode support |
| WO2014205399A1 (en) | 2013-06-21 | 2014-12-24 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation having rotatable shafts |
| US9707036B2 (en) | 2013-06-25 | 2017-07-18 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation using localized indifferent electrodes |
| AU2014284558B2 (en) | 2013-07-01 | 2017-08-17 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation |
| US10413357B2 (en) | 2013-07-11 | 2019-09-17 | Boston Scientific Scimed, Inc. | Medical device with stretchable electrode assemblies |
| US10660698B2 (en) | 2013-07-11 | 2020-05-26 | Boston Scientific Scimed, Inc. | Devices and methods for nerve modulation |
| WO2015010074A1 (en) | 2013-07-19 | 2015-01-22 | Boston Scientific Scimed, Inc. | Spiral bipolar electrode renal denervation balloon |
| EP3024405A1 (en) | 2013-07-22 | 2016-06-01 | Boston Scientific Scimed, Inc. | Renal nerve ablation catheter having twist balloon |
| EP3024406B1 (en) | 2013-07-22 | 2019-06-19 | Boston Scientific Scimed, Inc. | Medical devices for renal nerve ablation |
| JP6159888B2 (ja) | 2013-08-22 | 2017-07-05 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 腎神経変調バルーンへの接着性を向上させたフレキシブル回路 |
| US9895194B2 (en) | 2013-09-04 | 2018-02-20 | Boston Scientific Scimed, Inc. | Radio frequency (RF) balloon catheter having flushing and cooling capability |
| EP3043733A1 (en) | 2013-09-13 | 2016-07-20 | Boston Scientific Scimed, Inc. | Ablation balloon with vapor deposited cover layer |
| CA2925087C (en) | 2013-09-24 | 2024-02-13 | The Feinstein Institute For Medical Research | Peptides inhibiting cold-inducible rna binding protein activity |
| US9687166B2 (en) | 2013-10-14 | 2017-06-27 | Boston Scientific Scimed, Inc. | High resolution cardiac mapping electrode array catheter |
| US11246654B2 (en) | 2013-10-14 | 2022-02-15 | Boston Scientific Scimed, Inc. | Flexible renal nerve ablation devices and related methods of use and manufacture |
| WO2015057584A1 (en) | 2013-10-15 | 2015-04-23 | Boston Scientific Scimed, Inc. | Medical device balloon |
| US9770606B2 (en) | 2013-10-15 | 2017-09-26 | Boston Scientific Scimed, Inc. | Ultrasound ablation catheter with cooling infusion and centering basket |
| EP3057521B1 (en) | 2013-10-18 | 2020-03-25 | Boston Scientific Scimed, Inc. | Balloon catheters with flexible conducting wires |
| JP2016534842A (ja) | 2013-10-25 | 2016-11-10 | ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. | 除神経フレックス回路における埋め込み熱電対 |
| CN105899157B (zh) | 2014-01-06 | 2019-08-09 | 波士顿科学国际有限公司 | 抗撕裂柔性电路组件 |
| US9907609B2 (en) | 2014-02-04 | 2018-03-06 | Boston Scientific Scimed, Inc. | Alternative placement of thermal sensors on bipolar electrode |
| US11000679B2 (en) | 2014-02-04 | 2021-05-11 | Boston Scientific Scimed, Inc. | Balloon protection and rewrapping devices and related methods of use |
| US20160215031A1 (en) * | 2015-01-27 | 2016-07-28 | Nymox Pharnaceutical Corporation | Method of treating disorders requiring destruction or removal of cells |
| US10078207B2 (en) | 2015-03-18 | 2018-09-18 | Endochoice, Inc. | Systems and methods for image magnification using relative movement between an image sensor and a lens assembly |
| US20160361380A1 (en) | 2015-06-12 | 2016-12-15 | Nymox Corporation | Combination compositions for treating disorders requiring removal or destruction of unwanted cellular proliferations |
| WO2017000060A1 (en) * | 2015-06-29 | 2017-01-05 | The University Of British Columbia | Mammalian glucosidase inhibitors, methods for their use and pharmaceutical compositions thereof |
| US11628202B2 (en) * | 2015-07-24 | 2023-04-18 | Nymox Corporation | Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia |
| US10183058B2 (en) * | 2016-06-17 | 2019-01-22 | Nymox Corporation | Method of preventing or reducing the progression of prostate cancer |
| US10172910B2 (en) | 2016-07-28 | 2019-01-08 | Nymox Corporation | Method of preventing or reducing the incidence of acute urinary retention |
| US10532081B2 (en) | 2016-09-07 | 2020-01-14 | Nymox Corporation | Method of ameliorating or preventing the worsening or the progression of symptoms of BPH |
| US10335453B2 (en) | 2017-03-01 | 2019-07-02 | Nymox Corporation | Compositions and methods for improving sexual function |
| US10835538B2 (en) | 2018-03-28 | 2020-11-17 | Nymox Corporation | Method of treating benign prostatic hyperlasia with antibiotics |
| US20200061150A1 (en) | 2018-08-23 | 2020-02-27 | Nymox Corporation | Method of inducing selective prostate glandular pharmaco-ablation with sparing of nerves and preservation of sexual function |
| US11278588B2 (en) | 2019-05-13 | 2022-03-22 | Nymox Corporation | Method of treating lower urinary tract symptoms with fexapotide triflutate |
| US20200360466A1 (en) | 2019-05-13 | 2020-11-19 | Nymox Corporation | Method of improving lower urinary tract symptoms |
| US11298400B2 (en) | 2019-05-13 | 2022-04-12 | Nymox Corporation | Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS |
| US11231421B2 (en) | 2019-07-31 | 2022-01-25 | Nymox Corporation | Methods of treating multifocal cancer |
| US11331374B2 (en) | 2019-07-31 | 2022-05-17 | Nymox Corporation | Focal treatment of prostate cancer |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US594863A (en) * | 1897-12-07 | Otto p | ||
| US5169933A (en) * | 1988-08-15 | 1992-12-08 | Neorx Corporation | Covalently-linked complexes and methods for enhanced cytotoxicity and imaging |
| DE68927459T2 (de) * | 1988-12-21 | 1997-04-24 | Gen Hospital Corp | Nachweis einer neurologischen Krankheit oder einer Funktionsstörung |
| US5948634A (en) | 1988-12-21 | 1999-09-07 | The General Hospital Coporation | Neural thread protein gene expression and detection of alzheimer's disease |
| JPH06256387A (ja) | 1991-06-14 | 1994-09-13 | Suetsuna Yoko | 新規なペプチド、その製法およびそれを有効成分とする 血圧降下剤 |
| DE69434844T2 (de) | 1993-04-20 | 2006-12-14 | The General Hospital Corp., Boston | Geneexpression der neurofilamentproteine und nachweis der alzheimeschen erkrankung |
| FR2757486B1 (fr) | 1996-12-24 | 1999-03-26 | Sanofi Sa | Receptacle de conditionnement de deux produits pouvant s'ecouler et maintenus separes avant d'etre melanges pour utilisation |
| KR20000075748A (ko) | 1997-02-26 | 2000-12-26 | 마빈 씨. 구트리 | 알츠하이머 병의 치료 또는 예방에 유효한 약물을 선별하기 위한 유전자 변형동물 및 세포계 |
| US6238667B1 (en) * | 1997-09-19 | 2001-05-29 | Heinz Kohler | Method of affinity cross-linking biologically active immunogenic peptides to antibodies |
| JP2002519311A (ja) * | 1998-06-26 | 2002-07-02 | ジョージタウン・ユニバーシティ・メディカル・センター | 細胞死を誘発するための組成物と方法 |
| US7125957B1 (en) * | 1998-09-30 | 2006-10-24 | Riken | VPR mutant protein and its encoding gene having apoptosis-inducing action |
| WO2000034477A2 (en) * | 1998-12-11 | 2000-06-15 | Incyte Pharmaceuticals, Inc. | Neuron-associated proteins |
| ES2202039T3 (es) * | 1999-01-11 | 2004-04-01 | Leadd B.V. | Uso de agentes inductores de apoptosis en la preparacion de mrdicamentto para el tratamiento de enfermedades autoinmunitarias. |
| JP2002542766A (ja) | 1999-03-12 | 2002-12-17 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 50個のヒト分泌タンパク質 |
| WO2000058339A2 (en) | 1999-03-26 | 2000-10-05 | Human Genome Sciences, Inc. | 50 human secreted proteins |
| AU3628600A (en) | 1999-03-19 | 2000-10-09 | Human Genome Sciences, Inc. | 46 human secreted proteins |
| CA2368927A1 (en) | 1999-03-26 | 2000-10-05 | Craig A. Rosen | 45 human secreted proteins |
| JP2002541833A (ja) | 1999-03-26 | 2002-12-10 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | 49個のヒト分泌タンパク質 |
| WO2001035921A1 (en) | 1999-11-16 | 2001-05-25 | Unilever Plc | Cosmetic compositions containing anise extract and retinoids |
| WO2001040521A2 (en) | 1999-11-30 | 2001-06-07 | Curagen Corporation | Nucleic acids containing single nucleotide polymorphisms and methods of use thereof |
| CN1300779A (zh) | 1999-12-22 | 2001-06-27 | 上海博德基因开发有限公司 | 一种新的多肽-人神经元线蛋白17和编码这种多肽的多核苷酸 |
| CN1300783A (zh) | 1999-12-23 | 2001-06-27 | 上海生元基因开发有限公司 | 新的人神经元线蛋白及其编码序列 |
| EP1307488A2 (en) | 2000-06-26 | 2003-05-07 | Millennium Pharmaceuticals, Inc. | A human calcium channel protein and uses thereof |
| US6783969B1 (en) | 2001-03-05 | 2004-08-31 | Nuvelo, Inc. | Cathepsin V-like polypeptides |
| DE60205366T2 (de) * | 2001-05-16 | 2006-05-24 | Nymox Corp., Saint-Laurent | Prävention des zelltodes durch verwendung der segmente der neurofilamentproteine |
| WO2002097030A2 (en) | 2001-05-25 | 2002-12-05 | Nymox Corporation | Peptides derived from neural thread proteins and their medical use |
| JP4587667B2 (ja) * | 2001-07-19 | 2010-11-24 | ナイモックス コーポレーション | 細胞の除去又は破壊を必要とする腫瘍及び他の状態の治療に有効なペプチド |
| US7317077B2 (en) * | 2001-11-16 | 2008-01-08 | Nymox Pharmaceutical Corporation | Peptides effective in the treatment of tumors and other conditions requiring the removal or destruction of cells |
-
2002
- 2002-11-15 US US10/294,891 patent/US7317077B2/en not_active Expired - Fee Related
- 2002-11-18 AT AT02779063T patent/ATE333467T1/de active
- 2002-11-18 EA EA200400632A patent/EA007203B1/ru not_active IP Right Cessation
- 2002-11-18 KR KR1020147006037A patent/KR20140044399A/ko not_active Ceased
- 2002-11-18 WO PCT/CA2002/001757 patent/WO2003044053A2/en not_active Ceased
- 2002-11-18 JP JP2003545688A patent/JP4717349B2/ja not_active Expired - Fee Related
- 2002-11-18 PT PT02779063T patent/PT1442058E/pt unknown
- 2002-11-18 IL IL16159102A patent/IL161591A0/xx unknown
- 2002-11-18 DK DK02779063T patent/DK1442058T3/da active
- 2002-11-18 ES ES02779063T patent/ES2269775T3/es not_active Expired - Lifetime
- 2002-11-18 KR KR1020047007366A patent/KR20050044471A/ko not_active Ceased
- 2002-11-18 NZ NZ532721A patent/NZ532721A/en not_active IP Right Cessation
- 2002-11-18 EP EP02779063A patent/EP1442058B1/en not_active Expired - Lifetime
- 2002-11-18 KR KR1020107026566A patent/KR101375026B1/ko not_active Expired - Fee Related
- 2002-11-18 CN CNB028228014A patent/CN100509846C/zh not_active Expired - Fee Related
- 2002-11-18 BR BRPI0213786A patent/BRPI0213786B8/pt not_active IP Right Cessation
- 2002-11-18 MX MXPA04004489A patent/MXPA04004489A/es active IP Right Grant
- 2002-11-18 KR KR1020127024763A patent/KR20120123573A/ko not_active Ceased
- 2002-11-18 CA CA2467053A patent/CA2467053C/en not_active Expired - Fee Related
- 2002-11-18 DE DE60213274T patent/DE60213274T2/de not_active Expired - Lifetime
- 2002-11-18 AU AU2002342463A patent/AU2002342463B2/en not_active Ceased
- 2002-11-18 PL PL370891A patent/PL207591B1/pl unknown
-
2004
- 2004-04-22 IL IL161591A patent/IL161591A/en not_active IP Right Cessation
- 2004-05-04 NO NO20041844A patent/NO332842B1/no not_active IP Right Cessation
- 2004-05-12 ZA ZA2004/03624A patent/ZA200403624B/en unknown
- 2004-10-12 US US10/920,313 patent/US7408021B2/en not_active Expired - Lifetime
-
2006
- 2006-10-17 CY CY20061101487T patent/CY1107578T1/el unknown
-
2008
- 2008-07-11 US US12/171,462 patent/US8293703B2/en not_active Expired - Fee Related
-
2009
- 2009-06-15 US US12/484,696 patent/US7745572B2/en not_active Expired - Lifetime
-
2011
- 2011-01-24 JP JP2011011764A patent/JP5357196B2/ja not_active Expired - Fee Related
-
2012
- 2012-10-11 US US13/649,632 patent/US8569446B2/en not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2005521383A5 (enExample) | ||
| JP2005506061A5 (enExample) | ||
| JP2005507647A5 (enExample) | ||
| JP2004534533A5 (enExample) | ||
| JP2019196365A5 (enExample) | ||
| US7919098B2 (en) | ErbB-3 based methods and compositions for treating neoplasms | |
| CN102596217B (zh) | 经修饰的血管活性肠肽 | |
| JP2004529908A5 (enExample) | ||
| ES2400920T3 (es) | Péptidos eficaces en el tratamiento de tumores y otras afecciones que requieren la eliminación o la destrucción de células | |
| EP2281040B1 (en) | Lyophilized dna formulations for enhanced expression of plasmid dna | |
| JP2003531632A (ja) | グルカゴンアンタゴニスト | |
| JP2014519852A5 (enExample) | ||
| CA2371922A1 (en) | Methods and compositions for non-viral gene therapy for treatment of hyperproliferative diseases | |
| JP2008024710A (ja) | Jnkシグナル導入経路の細胞透過性ペプチドインヒビター | |
| JP2005530484A5 (enExample) | ||
| JP2021509104A (ja) | ヒトフェリチンおよびプロテアーゼ切断可能ペプチドに基づく融合タンパク質ならびに化学療法用担体としてのそれらの使用 | |
| JP2009545313A5 (enExample) | ||
| SK38998A3 (en) | Truncated glial cell line-derived neurotrophic factor | |
| JP2003530870A (ja) | Apo−AI/AIIペプチド誘導体 | |
| CN118750586A (zh) | 基于胶原的药物组合物和装置和生产方法及其用途 | |
| JP2004528266A (ja) | 薬物送達用組成物 | |
| JPWO2019140283A5 (ja) | アクチビンiib型受容体変異体および同変異体を含む医薬組成物 | |
| CN102209784A (zh) | 骨膜素诱导的胰腺再生 | |
| CA2378925A1 (en) | Matrix-targeted fusion polypeptides for tissue regeneration and wound healing | |
| CN100413888C (zh) | 可溶性多肽 |