JP2005519112A5 - - Google Patents

Download PDF

Info

Publication number
JP2005519112A5
JP2005519112A5 JP2003572946A JP2003572946A JP2005519112A5 JP 2005519112 A5 JP2005519112 A5 JP 2005519112A5 JP 2003572946 A JP2003572946 A JP 2003572946A JP 2003572946 A JP2003572946 A JP 2003572946A JP 2005519112 A5 JP2005519112 A5 JP 2005519112A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003572946A
Other languages
Japanese (ja)
Other versions
JP2005519112A (ja
JP4906233B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2003/006662 external-priority patent/WO2003074474A2/en
Publication of JP2005519112A publication Critical patent/JP2005519112A/ja
Publication of JP2005519112A5 publication Critical patent/JP2005519112A5/ja
Application granted granted Critical
Publication of JP4906233B2 publication Critical patent/JP4906233B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003572946A 2002-03-01 2003-03-03 少なくとも1種の有効薬剤成分を含有する多構成要素固相 Expired - Fee Related JP4906233B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US36076802P 2002-03-01 2002-03-01
US60/360,768 2002-03-01
PCT/US2003/006662 WO2003074474A2 (en) 2002-03-01 2003-03-03 Multiple-component solid phases containing at least one active pharmaceutical ingredient

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010089773A Division JP2010180239A (ja) 2002-03-01 2010-04-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相
JP2011195630A Division JP2012031180A (ja) 2002-03-01 2011-09-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相

Publications (3)

Publication Number Publication Date
JP2005519112A JP2005519112A (ja) 2005-06-30
JP2005519112A5 true JP2005519112A5 (https=) 2011-11-17
JP4906233B2 JP4906233B2 (ja) 2012-03-28

Family

ID=27789020

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2003572946A Expired - Fee Related JP4906233B2 (ja) 2002-03-01 2003-03-03 少なくとも1種の有効薬剤成分を含有する多構成要素固相
JP2010089773A Pending JP2010180239A (ja) 2002-03-01 2010-04-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相
JP2011195630A Pending JP2012031180A (ja) 2002-03-01 2011-09-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010089773A Pending JP2010180239A (ja) 2002-03-01 2010-04-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相
JP2011195630A Pending JP2012031180A (ja) 2002-03-01 2011-09-08 少なくとも1種の有効薬剤成分を含有する多構成要素固相

Country Status (7)

Country Link
US (4) US20030224006A1 (https=)
EP (1) EP1494998A2 (https=)
JP (3) JP4906233B2 (https=)
AU (1) AU2003213719A1 (https=)
CA (1) CA2477923C (https=)
IL (2) IL163846A0 (https=)
WO (1) WO2003074474A2 (https=)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004000284A1 (en) 2002-06-21 2003-12-31 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
US7790905B2 (en) 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
WO2004078163A2 (en) * 2003-02-28 2004-09-16 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
US7446107B2 (en) 2002-02-15 2008-11-04 Transform Pharmaceuticals, Inc. Crystalline forms of conazoles and methods of making and using the same
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
CA2477923C (en) 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
US20070059356A1 (en) * 2002-05-31 2007-03-15 Almarsson Oern Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
EP1511490A4 (en) 2002-05-31 2009-03-11 Transform Pharmaceuticals Inc NOVEL CONAZOLE CRYSTALLINE FORMS AND RELATED METHODS, PHARMACEUTICAL COMPOSITIONS AND METHODS
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
JP5069905B2 (ja) 2003-01-21 2012-11-07 アプテュイト (ウエスト ラファイエット)、エルエルシー 新規な共結晶化
ATE550022T1 (de) * 2003-02-28 2012-04-15 Mcneil Ppc Inc Pharmazeutische mischkristalle von celecoxib- nicotinamid
WO2004102151A2 (en) * 2003-05-06 2004-11-25 New Century Pharmaceuticals Albumin binding sites for evaluating drug interactions and methods of evaluating or designing drugs based on therir albumin binding properties
US7566805B2 (en) 2003-09-04 2009-07-28 Cephalon, Inc. Modafinil compositions
MXPA06002507A (es) * 2003-09-04 2006-06-20 Cephalon Inc Composiciones de modafinil.
WO2005041895A2 (en) * 2003-11-03 2005-05-12 New Century Pharmaceuticals, Inc. Albumin binding sites for evaluating drug interactions and methods of evaluating or designing drugs based on their albumin binding properties
CA2548281C (en) * 2003-12-09 2013-11-12 Medcrystalforms, Llc Method of preparation of mixed phase co-crystals with active agents
US20090018202A1 (en) 2004-02-06 2009-01-15 Cephalon, Inc. Modafinil compositions
WO2005092884A1 (en) * 2004-02-26 2005-10-06 Transform Pharmaceuticals, Inc. Novel crystalline forms of conazoles and methods of making and using the same
WO2005089375A2 (en) 2004-03-12 2005-09-29 S.S.C.I., Inc. Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound
WO2006007448A2 (en) 2004-06-17 2006-01-19 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions and related methods of use
US8779175B2 (en) 2004-10-25 2014-07-15 Synthonics, Inc. Coordination complexes, pharmaceutical solutions comprising coordination complexes, and methods of treating patients
US20080319068A1 (en) * 2005-04-27 2008-12-25 Transform Pharmaceuticals, Inc. Novel Polymorph of Acetylsalicylic Acid, and Methods of Making and Using the Same
US20070099237A1 (en) * 2005-10-31 2007-05-03 The Regents Of The University Of Michigan Reaction co-crystallization of molecular complexes or co-crystals
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
WO2008035960A2 (en) * 2006-09-21 2008-03-27 Avantium International B.V. Method for the preparation of a co-crystal
CA2668464A1 (en) * 2006-11-02 2008-06-19 University Of South Florida Materials and methods for co-crystal controlled solid-state synthesis of imides and imines
US7544830B2 (en) * 2007-01-10 2009-06-09 The University Of Connecticut Methods and systems for alkyl ester production
TW200901889A (en) * 2007-02-09 2009-01-16 Basf Se Crystalline complexes of agriculturally active organic compounds
HRP20120330T1 (hr) * 2007-02-27 2012-05-31 Vertex Pharmaceuticals Incorporated Sukristali i farmaceutski pripravci koji ih sadrže
WO2008108639A1 (en) * 2007-03-08 2008-09-12 Avantium Holding B.V. Co-crystalline forms of carbamazepine
WO2008153945A2 (en) 2007-06-06 2008-12-18 University Of South Florida Nutraceutical co-crystal compositions
US8471044B2 (en) * 2007-06-06 2013-06-25 University Of South Florida Epigallocatechin-3-gallate crystal compositions
GB0813709D0 (en) * 2008-07-26 2008-09-03 Univ Dundee Method and product
US8236787B2 (en) 2008-12-09 2012-08-07 Synthonics, Inc. Frequency modulated drug delivery (FMDD)
JP6074142B2 (ja) 2009-02-26 2017-02-01 タール ファーマシューティカルズ,インコーポレイテッド 医薬化合物の結晶化
JP5558875B2 (ja) * 2009-03-19 2014-07-23 日本曹達株式会社 新規包接錯体、エポキシ樹脂組成物及び半導体封止用エポキシ樹脂組成物
EP2413936B1 (en) * 2009-03-30 2016-11-02 Janssen Sciences Ireland UC Co-crystal of etravirine and nicotinamide
US10150792B2 (en) 2010-11-08 2018-12-11 Synthonics, Inc. Bismuth-containing compounds, coordination polymers, methods for modulating pharmacokinetic properties of biologically active agents, and methods for treating patients
CN102060777B (zh) * 2010-12-28 2012-11-21 吉林大学 苯妥英药物共晶及其制备方法
CN102060755B (zh) * 2010-12-28 2012-08-22 吉林大学 一种对乙酰氨基酚药物共晶及其制备方法
CA2831086A1 (en) 2011-03-24 2012-09-27 University Of South Florida Lithium compositions
MX2016001096A (es) 2013-07-25 2016-04-25 Basf Se Sales de dasatinib en forma amorfa.
WO2015011120A2 (en) * 2013-07-25 2015-01-29 Basf Se Salts of dasatinib in crystalline form
CN113754634A (zh) 2014-05-27 2021-12-07 R.J.雷诺兹烟草公司 烟碱盐、共晶体和盐共晶体络合物
US10508096B2 (en) 2014-05-27 2019-12-17 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
US9896429B2 (en) 2014-05-27 2018-02-20 R.J. Reynolds Tobacco Company Nicotine salts, co-crystals, and salt co-crystal complexes
KR102618114B1 (ko) * 2015-04-02 2023-12-27 라티오팜 게엠베하 이브루티닙과 카복실산의 공결정체
EP3297624B1 (en) * 2015-05-18 2021-03-03 Syn-Nat Products Enterprise LLC A pharmaceutical co-crystal and use thereof
CN119499220A (zh) * 2015-06-05 2025-02-25 密执安州立大学董事会 提高有机小分子生物利用度的方法及由其制造的沉积膜
US10500218B2 (en) * 2015-11-15 2019-12-10 Northwestern University Uptake of pharmaceuticals within cyclodextrin-based porous materials
DK3379952T3 (da) 2015-11-25 2024-01-08 Reynolds Tobacco Co R Nikotinsalte, co-krystaller og salt-co-krystalkomplekser
CN106823442A (zh) * 2017-03-08 2017-06-13 福建三农化学农药有限责任公司 一种全氟辛酸的回收方法和系统
PL3681865T3 (pl) 2017-09-05 2026-02-23 R. J. Reynolds Tobacco Company Sole, kokryształy i kompleksy kokryształów soli nikotyny
WO2022036291A1 (en) * 2020-08-14 2022-02-17 Board Of Regents, The University Of Texas System Method of producing pharmaceutical cocrystals for additive manufacturing
US20230338300A1 (en) * 2020-08-14 2023-10-26 Board Of Regents, The University Of Texas System Pharmaceutical composition containing cocrystals for additive manufacturing

Family Cites Families (193)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2711411A (en) * 1955-06-21 B-bromotheophylijne salt of z-amino-z-
US2554816A (en) 1950-04-04 1951-05-29 American Cyanamid Co Heterocyclic sulfonamides and methods of preparation thereof
US2665277A (en) * 1950-10-17 1954-01-05 Mallinckrodt Chemical Works Monobasic morphine phosphate hemihydrate and process of preparing same
US2980679A (en) 1957-04-04 1961-04-18 Omikron Gagliardi Societa Di F Process for preparing heterocyclic sulfonamides
US3020420A (en) * 1959-06-24 1962-02-06 Gen Electric Limiter circuit employing shunt diode means to sweep out distributed capacitance in the non-conducting state
US3028420A (en) 1959-06-26 1962-04-03 British Drug Houses Ltd Compound of betaine and chloral and method for preparing same
JPS4633588Y1 (https=) 1967-11-30 1971-11-19
GB1297261A (https=) * 1969-01-13 1972-11-22
US3536809A (en) 1969-02-17 1970-10-27 Alza Corp Medication method
US3598123A (en) * 1969-04-01 1971-08-10 Alza Corp Bandage for administering drugs
US3664858A (en) * 1970-02-18 1972-05-23 Minnesota Mining & Mfg Heat-sensitive copy-sheet
US3845770A (en) 1972-06-05 1974-11-05 Alza Corp Osmatic dispensing device for releasing beneficial agent
US3916899A (en) 1973-04-25 1975-11-04 Alza Corp Osmotic dispensing device with maximum and minimum sizes for the passageway
US3970651A (en) * 1974-01-07 1976-07-20 Bristol-Myers Company Crystalline cephalosporin derivative
JPS5842168B2 (ja) * 1974-12-20 1983-09-17 トウコウヤクヒンコウギヨウ カブシキガイシヤ 局所用剤の製造方法
US4008719A (en) * 1976-02-02 1977-02-22 Alza Corporation Osmotic system having laminar arrangement for programming delivery of active agent
JPS5416494A (en) 1977-07-08 1979-02-07 Yamanouchi Pharmaceut Co Ltd Complexes of crown ether with sulfonamides
JPS5495589A (en) 1977-12-30 1979-07-28 Sumitomo Chem Co Ltd Production of cephalosporin derivative
US4267179A (en) * 1978-06-23 1981-05-12 Janssen Pharmaceutica, N.V. Heterocyclic derivatives of (4-phenylpiperazin-1-yl-aryloxymethyl-1,3-dioxolan-2-yl)methyl-1H-imidazoles and 1H-1,2,4-triazoles
US4198507A (en) * 1978-11-13 1980-04-15 Hoffmann-La Roche Inc. Theophylline magnesium salicylate
US4368197A (en) * 1979-02-21 1983-01-11 Research Corporation Zinc aminophylline and its use in the treatment of bronchospasms
CA1148020A (en) * 1979-07-05 1983-06-14 James L. Bono Stable dehydrated cocrystalline amino acid food additives
JPS572367A (en) * 1980-06-07 1982-01-07 Kansai Paint Co Ltd Water-dispersed thermosetting resin slurry paint composition
DE3024158A1 (de) * 1980-06-27 1982-01-28 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung waermehaertender, mit wasser verduennbarer lacke fuer die beschichtung metallischer substrate
US5366738A (en) 1982-07-29 1994-11-22 Merck & Co., Inc. Controlled release drug dispersion delivery device
DE3365679D1 (en) * 1982-10-21 1986-10-02 Ici Plc Method of thickening aqueous latex compositions
LU84515A1 (fr) * 1982-12-09 1984-10-22 Oreal Composition stable pour corticotherapie locale a forte concentration hydrocortisone solubilisee
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
IE58110B1 (en) 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation
GB8500862D0 (en) 1985-01-14 1985-02-20 Tate & Lyle Plc Composition
GB8506792D0 (en) * 1985-03-15 1985-04-17 Janssen Pharmaceutica Nv Derivatives of y-cyclodextrin
FR2593809B1 (fr) * 1986-01-31 1988-07-22 Lafon Labor Benzhydrylsulfinylacetamide, procede de preparation et utilisation en therapeutique
US5091171B2 (en) 1986-12-23 1997-07-15 Tristrata Inc Amphoteric compositions and polymeric forms of alpha hydroxyacids and their therapeutic use
US4916134A (en) * 1987-03-25 1990-04-10 Janssen Pharmacuetica N.V. 4-[4-[4-[4-[[2-(2,4-difluorophenyl)-2-(1H-azolylmethyl)-1,3-dioxolan-4-yl]me]phenyl]-1-piperazinyl]phenyl]triazolones
NZ223799A (en) 1987-03-25 1989-12-21 Janssen Pharmaceutica Nv Azolylmethyl-dioxolanylmethoxyphenyl-piperazinyl-phenyl-triazolones and antimicrobial compositions
US4792569A (en) 1987-08-27 1988-12-20 Mcneilab, Inc. Anticonvulsant phenethyl sulfamates
JP2581707B2 (ja) 1987-10-02 1997-02-12 科研製薬株式会社 抗真菌剤組成物
US5006513A (en) * 1987-11-09 1991-04-09 Miles Inc. Antimycotic compositions of nikkomycin compounds and azole antimycotica
US5023092A (en) * 1988-06-16 1991-06-11 Ici Americas Inc. Mannitol having gamma sorbitol polymorph
US5073543A (en) 1988-07-21 1991-12-17 G. D. Searle & Co. Controlled release formulations of trophic factors in ganglioside-lipsome vehicle
US4925674A (en) * 1988-08-25 1990-05-15 Himedics, Inc. Amoxicillin microencapsulated granules
IT1229203B (it) 1989-03-22 1991-07-25 Bioresearch Spa Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative.
US5120548A (en) * 1989-11-07 1992-06-09 Merck & Co., Inc. Swelling modulated polymeric drug delivery device
US5190583A (en) * 1989-12-04 1993-03-02 Transfer-Electric Gesellschaft Fur Aqueous coating composition and the use thereof for coating to be protected from light, especially ultraviolet radiation
US4994604A (en) * 1990-01-10 1991-02-19 Merck & Co., Inc. Formation and resolution of ibuprofen lysinate
US5733566A (en) * 1990-05-15 1998-03-31 Alkermes Controlled Therapeutics Inc. Ii Controlled release of antiparasitic agents in animals
US5177262A (en) * 1991-07-19 1993-01-05 Polaroid Corporation Process and composition for use in photographic materials containing hydroquinones
IL103172A (en) 1991-09-19 1997-01-10 Mcneilab Inc Preparation of chlorosulfate and sulfamate derivatives of 2, 3:4, 5-bis-o-(1-methylethylidene)-beta-d-fructopyranose and (1-methylcyclohexyl) methanol
US5273760A (en) 1991-12-24 1993-12-28 Euroceltigue, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5286493A (en) * 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5472712A (en) 1991-12-24 1995-12-05 Euroceltique, S.A. Controlled-release formulations coated with aqueous dispersions of ethylcellulose
CA2117651C (en) 1992-03-18 2006-01-03 Jan Heeres Itraconazole and saperconazole stereoisomers
US5242942A (en) 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
US5258402A (en) 1992-06-11 1993-11-02 Mcneil-Ppc, Inc. Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates
US5324351A (en) 1992-08-13 1994-06-28 Euroceltique Aqueous dispersions of zein and preparation thereof
PH30929A (en) * 1992-09-03 1997-12-23 Janssen Pharmaceutica Nv Beads having a core coated with an antifungal and a polymer.
US5380867A (en) * 1992-12-02 1995-01-10 Hoechst Celanese Corporation Selective precipitation of α-aryl carboxylic acid salts
US5332834A (en) * 1992-12-02 1994-07-26 Hoechst Celanese Corporation Racemization of an enantomerically enriched α-aryl carboxylic acid
US5384327A (en) * 1992-12-22 1995-01-24 Mcneilab, Inc. Anticonvulsant sorbopyranose sulfamates
US5414997A (en) * 1993-01-11 1995-05-16 Tailer; Peter L. Thermal lag machine
US5591767A (en) * 1993-01-25 1997-01-07 Pharmetrix Corporation Liquid reservoir transdermal patch for the administration of ketorolac
JPH08509464A (ja) 1993-01-27 1996-10-08 セプラコア,インコーポレイテッド (2r,4s)イトラコナゾールを使用する方法および組成物
IT1263831B (it) 1993-01-29 1996-09-04 Paolo Chiesi Complessi di inclusione multicomponente ad elevata solubilita' costituiti da un farmaco di tipo basico, un acido ed una ciclodestrina
US5412094A (en) * 1993-06-28 1995-05-02 Eli Lilly And Company Bicyclic beta-lactam/paraben complexes
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
PH31594A (en) * 1993-09-30 1998-11-03 Janssen Pharmaceutica Nv Oral formulations on an antifungal.
ES2141916T3 (es) * 1993-11-30 2000-04-01 Searle & Co Pirazolil-bencenosulfonamidas sustituidas para el tratamiento de la inflamacion.
US5466823A (en) 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
PL181193B1 (pl) 1993-12-21 2001-06-29 Schering Corp Nowe pochodne tetrahydrofuranowe o działaniu przeciwgrzybicznym, kompozycja farmaceutyczna do leczenia infekcji grzybiczych oraz sposób wytwarzania tych związków
US5661151A (en) * 1993-12-21 1997-08-26 Schering Corporation Tetrahydrofuran antifungals
GB9404248D0 (en) 1994-03-05 1994-04-20 Boots Co Plc Pharmaceutical formulations
IT1270594B (it) 1994-07-07 1997-05-07 Recordati Chem Pharm Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida
FI944182A7 (fi) 1994-09-09 1996-03-10 Xyrofin Oy Yhtenäiskiteitä sisältävä koostumus, menetelmä sen valmistamiseksi ja sen käyttö
US5633272A (en) * 1995-02-13 1997-05-27 Talley; John J. Substituted isoxazoles for the treatment of inflammation
ES2183935T3 (es) 1995-02-13 2003-04-01 Searle & Co Isoxazoles sustituidos para el tratamiento de la inflamacion.
US5523090A (en) * 1995-02-24 1996-06-04 Chesebrough-Pond's Usa Co., Division Of Conopco, Inc. Skin treatment composition
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
US5631250A (en) 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
US5641512A (en) * 1995-03-29 1997-06-24 The Procter & Gamble Company Soft gelatin capsule compositions
TW457240B (en) 1995-04-20 2001-10-01 Janssen Pharmaceutica Nv Novel triazolones as apolipoprotein-B synthesis inhibitors
US5614342A (en) * 1995-05-02 1997-03-25 Eastman Kodak Company Methods for preparing cocrystals of titanyl fluorophthalocyanines and unsubstituted titanyl phthalocyanine, electrophotographic elements, and titanyl phthalocyanine compositions
US6001996A (en) 1995-05-11 1999-12-14 Eli Lilly And Company Complexes of cephalosporins and carbacephalosporins with parabens
US5780058A (en) 1995-07-21 1998-07-14 Alza Corporation Oral delivery of discrete units
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
US5952187A (en) 1995-12-01 1999-09-14 Oxis International, Inc. Topiramate immunoassay
US6132420A (en) 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US5635535A (en) * 1996-04-05 1997-06-03 Wagstaff; Robert K. Method for increasing blood glucose levels
SK285353B6 (sk) * 1996-04-12 2006-11-03 G. D. Searle & Co. Substituované benzénsulfónamidy ako proliečivá COX-2 inhibítorov, farmaceutická kompozícia a spôsobich prípravy a použitia
US5753693A (en) * 1996-06-28 1998-05-19 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating manic-depressive bipolar disorder
AP1285A (en) * 1996-06-28 2004-06-24 Ortho Mcneil Pharm Inc Anticonvulsant sulfamate derivatives useful in treating obesity.
US5994365A (en) 1997-02-25 1999-11-30 Diazans Limited Substituted diazaanthracene compounds having pharmaceutical utility
CA2232855C (en) * 1997-04-10 2007-10-09 Roche Consumer Health (Worldwide) Sa Pharmaceutical formulation
KR20010013377A (ko) * 1997-06-04 2001-02-26 데이비드 엠 모이어 마일드한 잔류성 항균 조성물
KR19990001564A (ko) 1997-06-16 1999-01-15 유충식 용해도를 개선한 아졸계 항진균제 및 이를 함유하는 제제
US5935933A (en) * 1997-07-16 1999-08-10 Ortho-Mcneil Pharmaceutical, Inc. Anticonvulsant derivatives useful in treating neuropathic pain
US5760007A (en) * 1997-07-16 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating neuropathic pain
MY125849A (en) 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
US5972986A (en) 1997-10-14 1999-10-26 G.D. Searle & Co. Method of using cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia
ES2182379T3 (es) * 1997-12-22 2003-03-01 Alza Corp Membrana de regulacion del regimen de liberacion para dispositivos de administracion controlada de farmacos.
JP4173635B2 (ja) * 1997-12-29 2008-10-29 インターシア セラピューティクス,インコーポレイティド 膜プラグ保持機構を有する浸透供給装置
AU1937099A (en) 1997-12-31 1999-07-19 Alza Corporation Osmotic drug delivery monitoring system and method
JP2002507511A (ja) 1998-01-21 2002-03-12 リフレキサイト・コーポレーション 長寿命ポリ塩化ビニル蛍光シ−ト材
US6245357B1 (en) * 1998-03-06 2001-06-12 Alza Corporation Extended release dosage form
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
US6541520B1 (en) 1998-08-05 2003-04-01 Brookhaven Science Associates Treatment of addiction and addiction-related behavior
US6890951B2 (en) * 1998-08-05 2005-05-10 Brookhaven Science Associates Llc Treatment of addiction and addiction-related behavior
IT1303251B1 (it) 1998-10-26 2000-11-06 Ind Chimica Srl Processo industriale per la purificazione di 2',3'- dideidro-3'-deossitimidina.
HUP0104993A3 (en) * 1998-11-02 2003-02-28 Alza Corp Mountain View Method and device for controlled delivery of active agents
JP2002528498A (ja) * 1998-11-02 2002-09-03 メルク エンド カムパニー インコーポレーテッド 片頭痛の治療方法及び医薬組成物
SA99191255B1 (ar) 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
US6342249B1 (en) * 1998-12-23 2002-01-29 Alza Corporation Controlled release liquid active agent formulation dosage forms
EP1144383A1 (en) 1999-01-14 2001-10-17 Merck Frosst Canada & Co. Synthesis of 4-[(5-substituted or unsubstituted phenyl)-3-substituted-1h-pyrazol-1-yl]benzenesulfonamides
ES2228465T3 (es) 1999-01-19 2005-04-16 Ortho-Mcneil Pharmaceutical, Inc. Uso derivados anticonvulsionantes para el tratamiento de cefaleas en brotes.
CN100548290C (zh) 1999-02-24 2009-10-14 辛辛那提大学 氨基磺酸酯衍生物用于治疗冲动控制障碍的用途
US6294192B1 (en) 1999-02-26 2001-09-25 Lipocine, Inc. Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents
EP1034826A1 (en) * 1999-03-05 2000-09-13 Reuter Chemische Apparatebau Co-crystallization process
JP4825353B2 (ja) * 1999-04-08 2011-11-30 オーソ−マクニール・フアーマシユーチカル・インコーポレーテツド 血圧を下げることに有用な抗痙攣薬誘導体
US6486198B1 (en) 1999-05-28 2002-11-26 Jeffrey Berlant Compounds and methods for the treatment of post traumatic stress disorder
US6413965B1 (en) * 1999-06-30 2002-07-02 Pfizer Inc. Compositions and treatment for diabetic complications
HUP0203198A3 (en) 1999-08-20 2005-07-28 Ortho Mcneil Pharm Inc Pharmaceutical composition comprising a tramadol material and an anticonvulsant drug, process for its preparation and its use
US6268385B1 (en) * 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
AU7331300A (en) * 1999-08-27 2001-03-26 Merck & Co., Inc. Method for treating or preventing chronic prostatitis or chronic pelvic pain syndrome
JP2003516353A (ja) * 1999-12-08 2003-05-13 ファルマシア コーポレイション ヴァルデコキシブ組成物
UA74539C2 (en) 1999-12-08 2006-01-16 Pharmacia Corp Crystalline polymorphous forms of celecoxib (variants), a method for the preparation thereof (variants), a pharmaceutical composition (variants)
ATE283048T1 (de) 1999-12-08 2004-12-15 Pharmacia Corp Cyclooxygenase-2 hemmer enthaltende zusammensetzungen mit schnellem wirkungseintritt
SK12682001A3 (sk) * 1999-12-08 2002-07-02 Pharmacia Corporation, Corporate Patent Department Celecoxib v tuhej forme so zvýšenou biologickou dostupnosťou
ES2236011T3 (es) 1999-12-08 2005-07-16 Pharmacia Corporation Formas cristalinas polimorficas de celecoxib.
US6376616B1 (en) * 1999-12-20 2002-04-23 Basf Corporation Pigment dispersants having anionic functionality for use in anodic electrocoat compositions
CN1434713A (zh) * 1999-12-22 2003-08-06 法马西亚公司 环加氧酶-2抑制剂的缓释制剂
SK9032002A3 (en) 1999-12-22 2003-03-04 Pharmacia Corp Dual-release compositions of a cyclooxygenase-2 inhibitor
US6348458B1 (en) * 1999-12-28 2002-02-19 U & I Pharmaceuticals Ltd. Polymorphic forms of olanzapine
WO2001051919A2 (en) 2000-01-07 2001-07-19 Transform Pharmaceuticals, Inc. High-throughput formation, identification, and analysis of diverse solid-forms
EP1120109A3 (en) * 2000-01-24 2002-07-10 Pfizer Products Inc. Rapidly disintegrating and fast dissolving solid dosage form
WO2001078724A1 (en) 2000-04-18 2001-10-25 Pharmacia Corporation Rapid-onset formulation of a selective cyclooxigenase-2
AR035642A1 (es) * 2000-05-26 2004-06-23 Pharmacia Corp Uso de una composicion de celecoxib para el alivio rapido del dolor
US6488962B1 (en) 2000-06-20 2002-12-03 Depomed, Inc. Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
GB0015239D0 (en) 2000-06-21 2000-08-16 Biochemie Gmbh Organic compounds
TR200001872A2 (tr) 2000-06-26 2002-01-21 Fako �La�Lari A.� 4-[5-(4-Metilfenil-3-(triflorometil)-1H-pirazol-1-il] benzensulfonamit' in yeni kristal biçimi "Biçim I" ve bu ürünün üretilmesine ilişkin yöntem.
US6191117B1 (en) * 2000-07-10 2001-02-20 Walter E. Kozachuk Methods of producing weight loss and treatment of obesity
CZ2003529A3 (cs) 2000-07-27 2003-09-17 Teva Pharmaceutical Industries Ltd. Krystalický a čistý modafinil a postup jeho přípravy
PE20020322A1 (es) 2000-08-18 2002-05-10 Pharmacia Corp Formulacion oral de rapida disolucion de un inhibidor de la ciclooxigenasa 2
JP2004506680A (ja) * 2000-08-18 2004-03-04 ファルマシア・コーポレーション シクロオキシゲナーゼ−2阻害剤の迅速崩壊経口製剤
US7141555B2 (en) 2000-12-19 2006-11-28 Cephalon, Inc. Modafinil compound and cyclodextrin mixtures
US7115565B2 (en) 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US6663897B2 (en) 2001-02-06 2003-12-16 Dsm Ip Assets B.V. Oral itraconazole formulations and methods of making the same
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
CN1266030C (zh) 2001-06-28 2006-07-26 住友化学工业株式会社 提纯氯的方法和生产1,2-二氯乙烷的方法
UA78211C2 (en) * 2001-07-09 2007-03-15 Ortho Mcneil Pharm Inc Salts of fructopyranose derivatives as anticonvulsant
WO2003033462A2 (en) 2001-10-15 2003-04-24 The Regents Of The University Of Michigan Systems and methods for the generation of crystalline polymorphs
CA2363376A1 (en) * 2001-11-16 2003-05-16 Bernard Charles Sherman Solid pharmaceutical compositions for oral administration comprising itraconazole
GB0203306D0 (en) 2002-02-12 2002-03-27 Norferm Da Method
WO2004000284A1 (en) * 2002-06-21 2003-12-31 Transform Pharmaceuticals, Inc. Pharmaceutical compositions with improved dissolution
US20090088443A1 (en) * 2002-02-15 2009-04-02 Julius Remenar Novel crystalline forms of conazoles and methods of making and using the same
WO2004078163A2 (en) 2003-02-28 2004-09-16 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
US6559293B1 (en) * 2002-02-15 2003-05-06 Transform Pharmaceuticals, Inc. Topiramate sodium trihydrate
US7927613B2 (en) * 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
WO2004060347A2 (en) 2002-09-03 2004-07-22 Transform Pharmaceuticals, Inc. Pharmaceutical propylene glycol solvate compositions
US7446107B2 (en) * 2002-02-15 2008-11-04 Transform Pharmaceuticals, Inc. Crystalline forms of conazoles and methods of making and using the same
WO2004089313A2 (en) 2003-04-01 2004-10-21 Transform Pharmaceuticals, Inc. Novel olanzapine forms and related methods of treatment
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
US20040171062A1 (en) 2002-02-28 2004-09-02 Plexxikon, Inc. Methods for the design of molecular scaffolds and ligands
CA2477923C (en) 2002-03-01 2021-02-23 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
US7205413B2 (en) * 2002-05-03 2007-04-17 Transform Pharmaceuticals, Inc. Solvates and polymorphs of ritonavir and methods of making and using the same
EP1364649A1 (en) 2002-05-23 2003-11-26 Cilag AG Adduct of topiramate and tramadol hydrochioride and uses thereof
EP1511490A4 (en) * 2002-05-31 2009-03-11 Transform Pharmaceuticals Inc NOVEL CONAZOLE CRYSTALLINE FORMS AND RELATED METHODS, PHARMACEUTICAL COMPOSITIONS AND METHODS
US20070059356A1 (en) * 2002-05-31 2007-03-15 Almarsson Oern Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
US6949139B2 (en) * 2002-12-02 2005-09-27 Eastman Kodak Company Process for forming cocrystals containing chlorine-free titanyl phthalocyanines and low concentration of titanyl fluorophthalocyanine using organic milling aid
US7033716B2 (en) * 2002-12-02 2006-04-25 Eastman Kodak Company Two-stage milling process for preparing cocrystals of titanyl fluorophthalocyanine and titanyl phthalocyanine, and electrophotographic element containing same
US7033715B2 (en) * 2002-12-02 2006-04-25 Eastman Kodak Company Uniform cocrystals of titanyl fluorophthalocyanine and titanyl phthalocyanine formed in trichloroethane, and charge generating layer containing same
MXPA05006210A (es) 2002-12-13 2005-08-19 Cilag Ag Preparaciones de liberacion controlada que comprenden tramadol y topiramato.
FR2849029B1 (fr) 2002-12-20 2005-03-18 Lafon Labor Procede de preparation et formes cristallines des enantiomeres optiques du modafinil.
JP5069905B2 (ja) 2003-01-21 2012-11-07 アプテュイト (ウエスト ラファイエット)、エルエルシー 新規な共結晶化
ATE550022T1 (de) 2003-02-28 2012-04-15 Mcneil Ppc Inc Pharmazeutische mischkristalle von celecoxib- nicotinamid
US6913830B2 (en) * 2003-08-14 2005-07-05 Ppg Industries Ohio, Inc. Coating compositions containing semiconductor colorants
US7566805B2 (en) * 2003-09-04 2009-07-28 Cephalon, Inc. Modafinil compositions
MXPA06002507A (es) 2003-09-04 2006-06-20 Cephalon Inc Composiciones de modafinil.
EP1667791A1 (en) 2003-10-06 2006-06-14 Solvias AG Process for the parallel detection of crystalline forms of molecular solids
EP1706098A4 (en) 2003-11-26 2012-08-15 Supernus Pharmaceuticals Inc MICRO-LAYER SYSTEMS FOR THE TRANSPORT OF LIPOPHILES AND BZW. HYDROPHOBIC COMPOUNDS
CA2548281C (en) 2003-12-09 2013-11-12 Medcrystalforms, Llc Method of preparation of mixed phase co-crystals with active agents
US20050176680A1 (en) 2003-12-11 2005-08-11 Sepracor, Inc. Combination of sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
ATE504588T1 (de) 2004-01-27 2011-04-15 Synthon Bv Stabile salze von olanzapin
CA2556106A1 (en) 2004-02-06 2005-08-25 Cephalon, Inc. Modafinil compositions
WO2005089375A2 (en) 2004-03-12 2005-09-29 S.S.C.I., Inc. Screening for solid forms by ultrasound crystallization and cocrystallization using ultrasound
EA011218B1 (ru) 2004-03-25 2009-02-27 Дзе Риджентс Оф Дзе Юниверсити Оф Мичиган Сокристаллы госсипола и их применение
WO2005118577A1 (en) 2004-04-22 2005-12-15 Transform Pharmaceuticals, Inc. Novel saperconazole crystalline forms and related processes, pharmaceutical compositions and methods
US20050252649A1 (en) 2004-05-11 2005-11-17 Ming-Chi Chiu Leadless lower temperature co-crystal phase transition metal heat conductive device
US7145005B2 (en) 2004-05-12 2006-12-05 Abbott Laboratories 2-(6-{2-[(2R)-2-Methyl-1-pyrrolidin-1-yl]-ethyl}-2-naphthalen-2-yl)-2H-pyridazin-3-one salts and their preparation
WO2006007448A2 (en) * 2004-06-17 2006-01-19 Transform Pharmaceuticals, Inc. Pharmaceutical co-crystal compositions and related methods of use
US7259869B2 (en) * 2004-06-29 2007-08-21 Kla-Tencor Technologies Corporation System and method for performing bright field and dark field optical inspection
WO2006024930A1 (en) 2004-09-01 2006-03-09 Pharmacia & Upjohn Company Llc Novel co-crystals between polyethylene glycols and 5-phenylpyrazolyl-1-benzenesulfonamides
US20080319068A1 (en) 2005-04-27 2008-12-25 Transform Pharmaceuticals, Inc. Novel Polymorph of Acetylsalicylic Acid, and Methods of Making and Using the Same
JP4633588B2 (ja) 2005-09-20 2011-02-16 Kddi株式会社 気象データ配信装置および局域気象データ配信システムならびに同システムにおける気象データ推定方法

Similar Documents

Publication Publication Date Title
BE2013C067I2 (https=)
BE2013C038I2 (https=)
BE2013C036I2 (https=)
BE2011C030I2 (https=)
IN2006DE00554A (https=)
JP2005519112A5 (https=)
BE2013C034I2 (https=)
JP2004023784A5 (https=)
BE2012C053I2 (https=)
JP2004046076A5 (https=)
JP2004190672A5 (https=)
JP2004005569A5 (https=)
JP2004048726A5 (https=)
JP2004047447A5 (https=)
JP2003310027A5 (https=)
JP2004130778A5 (https=)
JP2004046135A5 (https=)
JP2003297055A5 (https=)
AU2002340206A1 (https=)
AU2003210772A1 (https=)
AU2002316235A1 (https=)
AU2002311957A1 (https=)
AU2002353888A1 (https=)
AU2002310561A1 (https=)
AU2002256398A1 (https=)