JP2005517741A - インシュリン及びｉｇｆ−１レセプターのアゴニスト及びアンタゴニスト - Google Patents

インシュリン及びｉｇｆ−１レセプターのアゴニスト及びアンタゴニスト Download PDF

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JP2005517741A
JP2005517741A JP2003569654A JP2003569654A JP2005517741A JP 2005517741 A JP2005517741 A JP 2005517741A JP 2003569654 A JP2003569654 A JP 2003569654A JP 2003569654 A JP2003569654 A JP 2003569654A JP 2005517741 A JP2005517741 A JP 2005517741A
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seq
sequence
amino acid
group
formula
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Japanese (ja)
Inventor
レヌーカ ピルートラ，
レニー ブリセット，
アーサー， ジェイ． ブルーム，
ラウゲ シェファー，
ヤコブ ブラント，
ニール， アイ． ゴールドスタイン，
ジェーン スペツラー，
ソーレン オステルガール，
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ノボ・ノルデイスク・エー／エス
ディージーアイ バイオテクノロジーズ
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/65—Insulin-like growth factors, i.e. somatomedins, e.g. IGF-1, IGF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2003569654A 2001-09-24 2002-09-24 インシュリン及びｉｇｆ−１レセプターのアゴニスト及びアンタゴニスト Pending JP2005517741A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/962,756 US6875741B2 (en) 1998-09-02 2001-09-24 Insulin and IGF-1 receptor agonists and antagonists
PCT/US2002/030312 WO2003070747A2 (en) 2001-09-24 2002-09-24 Insulin and igf-1 receptor agonists and antagonists

Publications (1)

Publication Number Publication Date
JP2005517741A true JP2005517741A (ja) 2005-06-16

Family

ID=25506313

Family Applications (2)

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JP2003569654A Pending JP2005517741A (ja) 2001-09-24 2002-09-24 インシュリン及びｉｇｆ−１レセプターのアゴニスト及びアンタゴニスト
JP2003530818A Pending JP2005505579A (ja) 2001-09-24 2002-09-24 アンタゴニスト

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2003530818A Pending JP2005505579A (ja) 2001-09-24 2002-09-24 アンタゴニスト

Country Status (6)

Country Link
US (1) US6875741B2 (enExample)
EP (2) EP1496935A4 (enExample)
JP (2) JP2005517741A (enExample)
AU (2) AU2002341834A1 (enExample)
CA (2) CA2460055A1 (enExample)
WO (2) WO2003070747A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
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JP2009511446A (ja) * 2005-10-05 2009-03-19 ノボ・ノルデイスク・エー／エス インスリンレセプターアンタゴニストと、関連した組成物、使用及び方法

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US7632809B2 (en) * 2002-04-22 2009-12-15 Oncolix, Inc. Multimeric ligands with enhanced stability
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
JP2009511446A (ja) * 2005-10-05 2009-03-19 ノボ・ノルデイスク・エー／エス インスリンレセプターアンタゴニストと、関連した組成物、使用及び方法

Also Published As

Publication number Publication date
CA2460055A1 (en) 2003-08-28
AU2002366384A1 (en) 2003-09-09
WO2003070747A2 (en) 2003-08-28
WO2003027246A3 (en) 2003-07-31
EP1432433A4 (en) 2006-08-30
AU2002366384A8 (en) 2003-09-09
EP1432433A2 (en) 2004-06-30
EP1496935A2 (en) 2005-01-19
AU2002341834A1 (en) 2003-04-07
EP1496935A4 (en) 2006-06-07
WO2003027246A2 (en) 2003-04-03
US20030195147A1 (en) 2003-10-16
US6875741B2 (en) 2005-04-05
WO2003070747A3 (en) 2004-11-11
JP2005505579A (ja) 2005-02-24
CA2459999A1 (en) 2003-04-03

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