JP2005517647A - ノルエピネフリン再取り込み阻害物質の認知不全処置への使用 - Google Patents

ノルエピネフリン再取り込み阻害物質の認知不全処置への使用 Download PDF

Info

Publication number
JP2005517647A
JP2005517647A JP2003550773A JP2003550773A JP2005517647A JP 2005517647 A JP2005517647 A JP 2005517647A JP 2003550773 A JP2003550773 A JP 2003550773A JP 2003550773 A JP2003550773 A JP 2003550773A JP 2005517647 A JP2005517647 A JP 2005517647A
Authority
JP
Japan
Prior art keywords
norepinephrine reuptake
treatment
schizophrenia
atomoxetine
dementia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2003550773A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005517647A5 (enExample
Inventor
フランクリン・ポーター・バイマスター
ドナルド・リチャード・ゲーラート
デイビッド・リー・マッキンジー
チャールズ・レンキン・ヤン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of JP2005517647A publication Critical patent/JP2005517647A/ja
Publication of JP2005517647A5 publication Critical patent/JP2005517647A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
JP2003550773A 2001-12-11 2002-11-27 ノルエピネフリン再取り込み阻害物質の認知不全処置への使用 Pending JP2005517647A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33917401P 2001-12-11 2001-12-11
PCT/US2002/036132 WO2003049724A1 (en) 2001-12-11 2002-11-27 Use of norepinephrine reuptake inhibitors for the treatment of cognitive failure

Publications (2)

Publication Number Publication Date
JP2005517647A true JP2005517647A (ja) 2005-06-16
JP2005517647A5 JP2005517647A5 (enExample) 2006-01-26

Family

ID=23327833

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003550773A Pending JP2005517647A (ja) 2001-12-11 2002-11-27 ノルエピネフリン再取り込み阻害物質の認知不全処置への使用

Country Status (26)

Country Link
US (1) US20050009925A1 (enExample)
EP (1) EP1458368B1 (enExample)
JP (1) JP2005517647A (enExample)
KR (1) KR20040066895A (enExample)
CN (1) CN1713900A (enExample)
AU (1) AU2002352625A1 (enExample)
BR (1) BR0213581A (enExample)
CA (1) CA2467802A1 (enExample)
CO (1) CO5590907A2 (enExample)
CZ (1) CZ2004709A3 (enExample)
DE (1) DE60223718T2 (enExample)
EA (1) EA200400793A1 (enExample)
EC (1) ECSP045145A (enExample)
ES (1) ES2295435T3 (enExample)
HR (1) HRPK20040528B3 (enExample)
HU (1) HUP0402619A3 (enExample)
IL (1) IL161989A0 (enExample)
MX (1) MXPA04005716A (enExample)
MY (1) MY136367A (enExample)
NO (1) NO20042904L (enExample)
NZ (1) NZ532065A (enExample)
PL (1) PL369311A1 (enExample)
SK (1) SK2442004A3 (enExample)
TW (1) TW200300672A (enExample)
WO (1) WO2003049724A1 (enExample)
ZA (1) ZA200404274B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008516002A (ja) * 2005-09-07 2008-05-15 テバ ファーマシューティカル ファイン ケミカルズ ソチエタ レスポンサビリタ リミテ 塩酸アトモキセチンの調製方法

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050049476A (ko) * 2002-08-14 2005-05-25 파마시아 앤드 업존 캄파니 엘엘씨 홍조를 치료하기 위한 레복세틴의 용도
US20060100290A1 (en) * 2003-07-28 2006-05-11 Dunaway Leslie J Treatment of allergic rhinitis and asthma
US20070105960A1 (en) * 2003-08-27 2007-05-10 Eli Lilly And Company Treatment of learning disabilities and motor skills disorder with norepinephrine reuptake inhibitors
KR20060121178A (ko) * 2003-12-12 2006-11-28 일라이 릴리 앤드 캄파니 일과성 전신 열감, 충동 조절 장애 및 일반적인 의학상태로 인한 인격 변화 치료용 선택적 노르에피네프린재흡수 억제제
EA200601798A1 (ru) * 2004-04-30 2007-04-27 Уорнер-Ламберт Компани Ллс Замещенные соединения морфолина для лечения расстройств центральной нервной системы
US8580776B2 (en) * 2007-07-10 2013-11-12 The Board Of Trustees Of The University Of Illinois Compositions and methods for treating neurodegenerating diseases
US20100069389A1 (en) * 2008-09-06 2010-03-18 Bionevia Pharmaceuticals, Inc. Novel forms of reboxetine
US20100317731A1 (en) * 2009-06-12 2010-12-16 Shaya Elias K Hyperhidrosis treatment
WO2011014475A2 (en) * 2009-07-31 2011-02-03 National Taiwan University Treating negative symptoms of schizophrenia associated with defective neuregulin 1
WO2013051266A1 (ja) * 2011-10-03 2013-04-11 独立行政法人国立長寿医療研究センター タウ凝集阻害剤
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
US9907799B2 (en) 2013-04-02 2018-03-06 The Doshisha Tau aggregation inhibitor

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4314081A (en) * 1974-01-10 1982-02-02 Eli Lilly And Company Arloxyphenylpropylamines
US5281624A (en) * 1991-09-27 1994-01-25 Eli Lilly And Company N-alkyl-3-phenyl-3-(2-substituted phenoxy) propylamines and pharmaceutical use thereof
US5658590A (en) * 1995-01-11 1997-08-19 Eli Lilly And Company Treatment of attention-deficit/hyperactivity disorder
WO2001001973A2 (en) * 1999-07-01 2001-01-11 Pharmacia & Upjohn Company Highly selective norepinephrine reuptake inhibitors and methods of using the same
HK1047577B (zh) * 1999-10-13 2005-09-16 辉瑞产品公司 用作一元胺重摄取抑制剂的联芳醚衍生物
WO2002053104A2 (en) * 2001-01-02 2002-07-11 Sention, Inc. Use of catecholamine reuptake inhibitors to enhance memory
JP2004517112A (ja) * 2001-01-02 2004-06-10 ファルマシア・アンド・アップジョン・カンパニー 新規薬物コンビネーション

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008516002A (ja) * 2005-09-07 2008-05-15 テバ ファーマシューティカル ファイン ケミカルズ ソチエタ レスポンサビリタ リミテ 塩酸アトモキセチンの調製方法

Also Published As

Publication number Publication date
HUP0402619A3 (en) 2008-04-28
NO20042904L (no) 2004-09-07
TW200300672A (en) 2003-06-16
ES2295435T3 (es) 2008-04-16
IL161989A0 (en) 2005-11-20
CZ2004709A3 (cs) 2004-10-13
CN1713900A (zh) 2005-12-28
DE60223718D1 (de) 2008-01-03
WO2003049724A1 (en) 2003-06-19
AU2002352625A1 (en) 2003-06-23
EP1458368B1 (en) 2007-11-21
US20050009925A1 (en) 2005-01-13
HRPK20040528B3 (en) 2006-03-31
KR20040066895A (ko) 2004-07-27
HUP0402619A2 (hu) 2005-03-29
CA2467802A1 (en) 2003-06-19
CO5590907A2 (es) 2005-12-30
DE60223718T2 (de) 2008-10-30
SK2442004A3 (en) 2004-12-01
NZ532065A (en) 2007-03-30
EA200400793A1 (ru) 2004-10-28
ZA200404274B (en) 2005-09-13
MXPA04005716A (es) 2004-12-06
HRP20040528A2 (en) 2004-10-31
ECSP045145A (es) 2004-07-23
EP1458368A1 (en) 2004-09-22
MY136367A (en) 2008-09-30
PL369311A1 (en) 2005-04-18
BR0213581A (pt) 2004-08-24

Similar Documents

Publication Publication Date Title
JP2006515628A (ja) ヒト神経精神疾患を処置するためのn−デスメチルクロザピンの使用
EP1238676B1 (en) Combination of a serotonin reuptake inhibitor and an atypical antipsychotic for use in depression, obsessive compulsive disorder and psychosis
JP2009531435A (ja) うつ病の治療用の新規な治療組み合わせ
JP2005517647A (ja) ノルエピネフリン再取り込み阻害物質の認知不全処置への使用
KR20010024218A (ko) 반항성 장애의 치료
US6960577B2 (en) Combination therapy for treatment of refractory depression
EP0958824A2 (en) Olanzapine (zyprexa) in combination with fluoxetine (prozac), lithium or anticonvulsant for therapy of refractory depression
JP2023546238A (ja) 慢性的なssriレジメンの後にシロシビンに対する感受性を高めるためのベンゾジアゼピンの使用
JP2012522033A (ja) 気分障害の治療における低用量ピパンペロン
EP1262197A2 (en) Combination treatment for sleep disorders including sleep apnea
US20030055070A1 (en) Phosphodiesterase type 5 (PDE5) inhibitors for the treatment of selective serotonin reuptake inhibitor (SSR) induced sexual dysfunction
JP2004529073A (ja) 不安障害の治療
KR20060020664A (ko) 과체중 또는 과체중 경향을 가진 환자에서 정신 분열증의치료를 위한 아세나핀
JP2015524474A (ja) 治療レジメン
ES2284830T3 (es) Uso de quetiapina para el tratamiento de la cocaina.
JP2005513105A (ja) 臨床的うつ病を治療するためのデオキシペガニンの使用
SK14502000A3 (sk) Kombinácie liekov n. a. r. i. (inhibítorov reaktivácie noradrenalínu), výhodne reboxetínu, a pindololu
JP2005515199A (ja) チック障害の治療のためのノルエピネフリン再取込インヒビターの使用
RU2238084C2 (ru) Композиции, содержащие ингибиторы обратного захвата допамина, и способы их применения
CN119384278A (zh) 治疗精神类疾病的方法
HK40071665B (zh) 在痴呆患者中治疗行为和精神症状
EA049112B1 (ru) Использование бензодиазепинов для повышения чувствительности к псилоцибину после длительного приема сиозс
HK1059391B (en) Use of quetiapine for the treatment of cocaine dependence
MXPA00011353A (es) Uso de olanzapida en combinación con fluoxetina para terapia de la depresión refractaria
HK1084894B (en) Asenapine for the treatment of schizophrenia in a patient with overweight or predisposition for overweight

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20051125

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20051125

RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20080911

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090120

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20090623