JP2005507365A5 - - Google Patents
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- Publication number
- JP2005507365A5 JP2005507365A5 JP2002573735A JP2002573735A JP2005507365A5 JP 2005507365 A5 JP2005507365 A5 JP 2005507365A5 JP 2002573735 A JP2002573735 A JP 2002573735A JP 2002573735 A JP2002573735 A JP 2002573735A JP 2005507365 A5 JP2005507365 A5 JP 2005507365A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- carbon atoms
- halogen
- substituted
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26265101P | 2001-01-22 | 2001-01-22 | |
| US26719601P | 2001-02-08 | 2001-02-08 | |
| US30614001P | 2001-07-19 | 2001-07-19 | |
| PCT/US2002/001508 WO2002074726A2 (en) | 2001-01-22 | 2002-01-22 | Aniline derivatives useful as phosphodiesterase 4 inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005507365A JP2005507365A (ja) | 2005-03-17 |
| JP2005507365A5 true JP2005507365A5 (cg-RX-API-DMAC7.html) | 2008-02-21 |
| JP4223287B2 JP4223287B2 (ja) | 2009-02-12 |
Family
ID=27401532
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002573735A Expired - Fee Related JP4223287B2 (ja) | 2001-01-22 | 2002-01-22 | 新規な化合物及び製薬上許容し得るそれらの塩並びにそれらを用いた薬剤組成物 |
Country Status (23)
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7153871B2 (en) | 2001-01-22 | 2006-12-26 | Memory Pharmaceuticals Corporation | Phosphodiesterase 4 inhibitors, including aminoindazole and aminobenzofuran analogs |
| DK1363876T3 (da) * | 2001-02-14 | 2009-11-30 | Karobio Ab | Glucocorticoidreceptormodulatorer |
| JP2006504656A (ja) * | 2002-07-19 | 2006-02-09 | メモリー・ファーマシューティカルズ・コーポレイション | Ｎ−置換されたアニリン及びジフェニルアミンアナログを含むホスホジエステラーゼ４インヒビター |
| JP2006502995A (ja) | 2002-07-19 | 2006-01-26 | メモリー・ファーマシューティカルズ・コーポレイション | ホスホジエステラーゼ４阻害剤としての６−アミノ−１ｈ−インダゾール及び４−アミノベンゾフラン化合物 |
| EP1569908B1 (en) | 2002-11-19 | 2010-09-15 | Memory Pharmaceuticals Corporation | Pyridine n-oxide compounds as phosphodiesterase 4 inhibitors |
| AU2003286024A1 (en) * | 2002-11-22 | 2004-06-18 | Daniel Dube | Use of phosphodiesterase-4 inhibitors as enhancers of cognition |
| ES2282701T3 (es) * | 2002-12-27 | 2007-10-16 | H. Lundbeck A/S | Derivados de 1,2,4-triaminobenceno utiles para tratar trastornos del sistema nervioso central. |
| FR2856595B1 (fr) * | 2003-06-27 | 2008-05-30 | Exonhit Therapeutics Sa | Methodes et compositions pour le traitement de deficits cognitifs. |
| WO2005023253A1 (en) | 2003-09-05 | 2005-03-17 | Altana Pharma Ag | Use of pde4 inhibitors for the treatment of diabetes mellitus |
| MY141255A (en) * | 2003-12-11 | 2010-03-31 | Memory Pharm Corp | Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs |
| CN1984906A (zh) | 2004-07-15 | 2007-06-20 | 日本烟草产业株式会社 | 稠合苯甲酰胺化合物和香草素受体1(vr1)活性抑制剂 |
| CA2585210A1 (en) * | 2004-10-28 | 2006-05-11 | Merck & Co., Inc. | Pyrimidine and quinoline potentiators of metabotropic glutamate receptors |
| US8017633B2 (en) | 2005-03-08 | 2011-09-13 | Nycomed Gmbh | Roflumilast for the treatment of diabetes mellitus |
| JP2008543781A (ja) * | 2005-06-10 | 2008-12-04 | メモリー・ファーマシューティカルズ・コーポレイション | ホスフオジエステラーゼ４阻害剤 |
| AR057455A1 (es) | 2005-07-22 | 2007-12-05 | Merck & Co Inc | Inhibidores de la transcriptasa reversa de vih y composicion farmaceutica |
| US7906508B2 (en) | 2005-12-28 | 2011-03-15 | Japan Tobacco Inc. | 3,4-dihydrobenzoxazine compounds and inhibitors of vanilloid receptor subtype 1 (VRI) activity |
| CA2676715A1 (en) | 2007-02-12 | 2008-08-21 | Merck & Co., Inc. | Piperazine derivatives for treatment of ad and related conditions |
| EP2110375A1 (en) | 2008-04-14 | 2009-10-21 | CHIESI FARMACEUTICI S.p.A. | Phosphodiesterase-4 inhibitors belonging to the tertiary amine class |
| US8461389B2 (en) | 2008-04-18 | 2013-06-11 | University College Dublin, National University Of Ireland, Dublin | Psycho-pharmaceuticals |
| JP5542059B2 (ja) * | 2008-10-09 | 2014-07-09 | 国立大学法人 岡山大学 | Ｒｘｒ作動性物質を有効成分とする抗アレルギー剤 |
| HRP20191460T1 (hr) * | 2009-06-12 | 2019-11-15 | Abivax | Spojevi korisni za liječenje raka |
| CA2764026C (en) | 2009-06-12 | 2019-10-29 | Splicos | Compounds useful for treating aids |
| US10253020B2 (en) | 2009-06-12 | 2019-04-09 | Abivax | Compounds for preventing, inhibiting, or treating cancer, AIDS and/or premature aging |
| CN107260736A (zh) | 2010-02-12 | 2017-10-20 | 株式会社ＡｓｋＡｔ | 用于治疗痴呆的5‑ht4受体激动剂 |
| US9550763B2 (en) | 2012-02-09 | 2017-01-24 | Shionogi & Co., Ltd. | Heterocyclic ring and carbocyclic derivative |
| CN102603676B (zh) * | 2012-02-20 | 2014-02-12 | 徐江平 | 一种能避免呕吐反应的磷酸二酯酶4抑制剂 |
| JP5959670B2 (ja) * | 2012-03-14 | 2016-08-02 | シノケム・コーポレーションＳｉｎｏｃｈｅｍ Ｃｏｒｐｏｒａｔｉｏｎ | 抗腫瘍薬の調製における置換ジフェニルアミン化合物の使用 |
| EP2757161A1 (en) | 2013-01-17 | 2014-07-23 | Splicos | miRNA-124 as a biomarker of viral infection |
| EP3016656B1 (en) | 2013-07-05 | 2021-09-08 | Abivax | Bicyclic compounds useful for treating diseases caused by retroviruses |
| US10357486B2 (en) | 2013-08-16 | 2019-07-23 | Universiteit Maastricht | Treatment of cognitive impairment with PDE4 inhibitor |
| EP2974729A1 (en) | 2014-07-17 | 2016-01-20 | Abivax | Quinoline derivatives for use in the treatment of inflammatory diseases |
| EP3669873A1 (en) | 2018-12-20 | 2020-06-24 | Abivax | Quinoline derivatives for use ine the traeatment of inflammation diseases |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0700389A1 (en) | 1993-05-27 | 1996-03-13 | Smithkline Beecham Laboratoires Pharmaceutiques | Anti-arrhythmic n-substituted 3-benzazepines or isoquinolines |
| JPH07206789A (ja) * | 1993-09-01 | 1995-08-08 | Taisho Pharmaceut Co Ltd | コンブレタスタチン類縁化合物 |
| US5591776A (en) * | 1994-06-24 | 1997-01-07 | Euro-Celtique, S.A. | Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV |
| FR2729142A1 (fr) * | 1995-01-06 | 1996-07-12 | Smithkline Beecham Lab | Nouvelles amines heterocycliques, leur procede de preparation et leur utilisation en tant que medicaments et notamment en tant qu'agents anti-arythmiques |
| WO1998058901A1 (en) * | 1997-06-24 | 1998-12-30 | Nikken Chemicals Co., Ltd. | 3-anilino-2-cycloalkenone derivates |
| PL204437B1 (pl) * | 1999-05-21 | 2010-01-29 | Bristol Myers Squibb Co | Pochodna pirolotriazyny i jej zastosowanie oraz kompozycja farmaceutyczna i jej zastosowanie |
| ATE312808T1 (de) * | 1999-12-18 | 2005-12-15 | Wella Ag | 2-aminoalkyl-1,4-diaminobenzol-derivate und diese verbindungen enthaltende färbemittel |
-
2002
- 2002-01-22 NZ NZ527081A patent/NZ527081A/xx unknown
- 2002-01-22 WO PCT/US2002/001508 patent/WO2002074726A2/en not_active Ceased
- 2002-01-22 CA CA002435847A patent/CA2435847A1/en not_active Abandoned
- 2002-01-22 JP JP2002573735A patent/JP4223287B2/ja not_active Expired - Fee Related
- 2002-01-22 HR HR20030662A patent/HRP20030662A2/hr not_active Application Discontinuation
- 2002-01-22 BR BR0206943-1A patent/BR0206943A/pt not_active Application Discontinuation
- 2002-01-22 EP EP02731078A patent/EP1353907A2/en not_active Withdrawn
- 2002-01-22 IL IL15695802A patent/IL156958A0/xx unknown
- 2002-01-22 AU AU2002303078A patent/AU2002303078B2/en not_active Ceased
- 2002-01-22 EE EEP200300347A patent/EE05362B1/xx not_active IP Right Cessation
- 2002-01-22 MX MXPA03006519A patent/MXPA03006519A/es active IP Right Grant
- 2002-01-22 SK SK915-2003A patent/SK9152003A3/sk unknown
- 2002-01-22 HU HU0302793A patent/HUP0302793A3/hu unknown
- 2002-01-22 YU YU57603A patent/YU57603A/sh unknown
- 2002-01-22 KR KR1020037009624A patent/KR100856622B1/ko not_active Expired - Fee Related
- 2002-01-22 PL PL02373301A patent/PL373301A1/xx not_active Application Discontinuation
- 2002-01-22 CZ CZ20031986A patent/CZ20031986A3/cs unknown
- 2002-01-22 CN CNB028070100A patent/CN100378075C/zh not_active Expired - Fee Related
-
2003
- 2003-07-18 BG BG108003A patent/BG108003A/bg unknown
- 2003-07-21 ZA ZA2003/05623A patent/ZA200305623B/en unknown
- 2003-07-21 NO NO20033288A patent/NO329548B1/no not_active IP Right Cessation
- 2003-07-22 MA MA27246A patent/MA25996A1/fr unknown
-
2004
- 2004-05-20 CL CL200401165A patent/CL2004001165A1/es unknown
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