JP2004533240A5 - - Google Patents

Info

Publication number

JP2004533240A5

JP2004533240A5 JP2002583669A JP2002583669A JP2004533240A5 JP 2004533240 A5 JP2004533240 A5 JP 2004533240A5 JP 2002583669 A JP2002583669 A JP 2002583669A JP 2002583669 A JP2002583669 A JP 2002583669A JP 2004533240 A5 JP2004533240 A5 JP 2004533240A5

Authority

JP

Japan

Prior art keywords

amino acid

acid sequence

polypeptide

seq

polynucleotide

Prior art date

2002-04-23

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• 125000003275 alpha amino acid group Chemical group 0.000 claims 43
• 229920001184 polypeptide Polymers 0.000 claims 30
• 108090000765 processed proteins & peptides Proteins 0.000 claims 30
• 102000004196 processed proteins & peptides Human genes 0.000 claims 30
• 108091033319 polynucleotide Proteins 0.000 claims 24
• 102000040430 polynucleotide Human genes 0.000 claims 24
• 239000002157 polynucleotide Substances 0.000 claims 24
• 239000002773 nucleotide Substances 0.000 claims 22
• 125000003729 nucleotide group Chemical group 0.000 claims 22
• 238000000034 method Methods 0.000 claims 21
• 210000004027 cell Anatomy 0.000 claims 16
• 150000001875 compounds Chemical class 0.000 claims 16
• 102220089612 rs869312939 Human genes 0.000 claims 15
• 230000000694 effects Effects 0.000 claims 14
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 12
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 10
• 150000001413 amino acids Chemical class 0.000 claims 9
• 201000010099 disease Diseases 0.000 claims 9
• 239000003795 chemical substances by application Substances 0.000 claims 8
• 108091026890 Coding region Proteins 0.000 claims 7
• 239000003814 drug Substances 0.000 claims 7
• 230000002401 inhibitory effect Effects 0.000 claims 6
• 230000004071 biological effect Effects 0.000 claims 5
• 108090000623 proteins and genes Proteins 0.000 claims 5
• 230000000295 complement effect Effects 0.000 claims 4
• 230000003389 potentiating effect Effects 0.000 claims 4
• 238000004519 manufacturing process Methods 0.000 claims 3
• 102220205652 rs1057522121 Human genes 0.000 claims 3
• 229940124597 therapeutic agent Drugs 0.000 claims 3
• 208000035473 Communicable disease Diseases 0.000 claims 2
• 108090000695 Cytokines Proteins 0.000 claims 2
• 102000004127 Cytokines Human genes 0.000 claims 2
• 206010028980 Neoplasm Diseases 0.000 claims 2
• 230000003213 activating effect Effects 0.000 claims 2
• 239000013543 active substance Substances 0.000 claims 2
• 230000001028 anti-proliverative effect Effects 0.000 claims 2
• 208000015114 central nervous system disease Diseases 0.000 claims 2
• 238000003205 genotyping method Methods 0.000 claims 2
• 208000015181 infectious disease Diseases 0.000 claims 2
• 239000003112 inhibitor Substances 0.000 claims 2
• 208000030507 AIDS Diseases 0.000 claims 1
• 206010059313 Anogenital warts Diseases 0.000 claims 1
• 208000024172 Cardiovascular disease Diseases 0.000 claims 1
• 208000000419 Chronic Hepatitis B Diseases 0.000 claims 1
• 208000006154 Chronic hepatitis C Diseases 0.000 claims 1
• 208000000907 Condylomata Acuminata Diseases 0.000 claims 1
• 208000005176 Hepatitis C Diseases 0.000 claims 1
• 108010067902 Peptide Library Proteins 0.000 claims 1
• 206010035664 Pneumonia Diseases 0.000 claims 1
• 108010076504 Protein Sorting Signals Proteins 0.000 claims 1
• 208000019802 Sexually transmitted disease Diseases 0.000 claims 1
• 210000001744 T-lymphocyte Anatomy 0.000 claims 1
• 208000036142 Viral infection Diseases 0.000 claims 1
• 208000025009 anogenital human papillomavirus infection Diseases 0.000 claims 1
• 201000004201 anogenital venereal wart Diseases 0.000 claims 1
• 230000000840 anti-viral effect Effects 0.000 claims 1
• 230000001363 autoimmune Effects 0.000 claims 1
• 201000011510 cancer Diseases 0.000 claims 1
• 238000002512 chemotherapy Methods 0.000 claims 1
• 238000012258 culturing Methods 0.000 claims 1
• 230000003247 decreasing effect Effects 0.000 claims 1
• 230000004041 dendritic cell maturation Effects 0.000 claims 1
• 208000035475 disorder Diseases 0.000 claims 1
• 238000009510 drug design Methods 0.000 claims 1
• 230000002708 enhancing effect Effects 0.000 claims 1
• 208000002672 hepatitis B Diseases 0.000 claims 1
• 208000010710 hepatitis C virus infection Diseases 0.000 claims 1
• 238000013537 high throughput screening Methods 0.000 claims 1
• 230000001900 immune effect Effects 0.000 claims 1
• 238000000338 in vitro Methods 0.000 claims 1
• 238000001727 in vivo Methods 0.000 claims 1
• 230000002458 infectious effect Effects 0.000 claims 1
• 108020004999 messenger RNA Proteins 0.000 claims 1
• 208000030159 metabolic disease Diseases 0.000 claims 1
• 210000001616 monocyte Anatomy 0.000 claims 1
• 108091027963 non-coding RNA Proteins 0.000 claims 1
• 102000042567 non-coding RNA Human genes 0.000 claims 1
• 230000008488 polyadenylation Effects 0.000 claims 1
• 210000004896 polypeptide structure Anatomy 0.000 claims 1
• 230000002265 prevention Effects 0.000 claims 1
• 238000004393 prognosis Methods 0.000 claims 1
• 230000000087 stabilizing effect Effects 0.000 claims 1
• 230000009385 viral infection Effects 0.000 claims 1