ES2167537T3 - Procedimiento para la produccion de proteinas. - Google Patents

Procedimiento para la produccion de proteinas.

Info

Publication number
ES2167537T3
ES2167537T3 ES96900977T ES96900977T ES2167537T3 ES 2167537 T3 ES2167537 T3 ES 2167537T3 ES 96900977 T ES96900977 T ES 96900977T ES 96900977 T ES96900977 T ES 96900977T ES 2167537 T3 ES2167537 T3 ES 2167537T3
Authority
ES
Spain
Prior art keywords
production
proteins
procedure
protein
genes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96900977T
Other languages
English (en)
Inventor
Bernd Meyhack
Michael Broker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Sanofi Aventis Deutschland GmbH
Original Assignee
Novartis AG
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis AG, Aventis Pharma Deutschland GmbH filed Critical Novartis AG
Application granted granted Critical
Publication of ES2167537T3 publication Critical patent/ES2167537T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8132—Plasminogen activator inhibitors

Abstract

LA INVENCION PERTENECE AL CAMPO DE LA TECNOLOGIA DEL ADN RECOMBINANTE Y SE REFIERE A UN METODO PARA LA PRODUCCION DE UNA PROTEINA HETEROLOGA A LEVADURAS EN UNA FORMA HOMOGENEA CON AYUDA DE UNA CEPA DE SACCHAROMYCES CEREVISIAE HT393 O UN DERIVADO DE LA MISMA CON UN VECTOR HIBRIDO QUE INCLUYE LOS GENES DE DICHA PROTEINA.
ES96900977T 1995-02-09 1996-01-26 Procedimiento para la produccion de proteinas. Expired - Lifetime ES2167537T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95810084 1995-02-09

Publications (1)

Publication Number Publication Date
ES2167537T3 true ES2167537T3 (es) 2002-05-16

Family

ID=8221698

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96900977T Expired - Lifetime ES2167537T3 (es) 1995-02-09 1996-01-26 Procedimiento para la produccion de proteinas.

Country Status (10)

Country Link
US (2) US5981227A (es)
EP (1) EP0801682B1 (es)
JP (1) JP3732516B2 (es)
AT (1) ATE207538T1 (es)
AU (1) AU707657B2 (es)
DE (1) DE69616276T2 (es)
DK (1) DK0801682T3 (es)
ES (1) ES2167537T3 (es)
PT (1) PT801682E (es)
WO (1) WO1996024678A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5981227A (en) * 1995-02-09 1999-11-09 Movartis Ag Process for the production of proteins
FR2801902B1 (fr) * 1999-12-01 2005-03-04 Centre Nat Rech Scient Procedes de criblages fonctionnels d'agents aptes a moduler l'activite des complexes ubiquitine-ligases scf et leurs applications
FR2823764B1 (fr) * 2001-04-24 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides du gene ifn alpha-17

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2108510B (en) 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
PH22337A (en) 1983-11-21 1988-08-12 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast
US4923807A (en) * 1984-05-18 1990-05-08 New England Medical Center Hospitals Inc. Arg-Serpin human plasminogen activator inhibitor designated PAI-2
ATE78262T1 (de) 1985-06-11 1992-08-15 Ciba Geigy Ag Hybrid-interferone.
MY101203A (en) 1985-12-12 1991-08-17 Ucp Gen Pharma Ag Production of thrombin iinhibitors.
AU614121B2 (en) * 1988-05-04 1991-08-22 Novartis Ag Improvements in the production of polypeptides
CA1324969C (en) * 1988-05-06 1993-12-07 Jeffrey R. Shuster High level expression of proteins in yeast
JPH02150283A (ja) * 1988-07-21 1990-06-08 Takeda Chem Ind Ltd 発現プラスミドおよびその用途
JP2840441B2 (ja) * 1988-11-04 1998-12-24 カイロン・コーポレーション 真正ｆｇｆの酵母における発現およびプロセシング
NZ236434A (en) * 1990-01-29 1992-08-26 Ciba Geigy Ag Dna molecules comprising the a niger pyruvate kinase transcription promoter, vectors containing it and their use in transforming host cells
ATE190657T1 (de) * 1994-12-16 2000-04-15 Chiron Behring Gmbh & Co Immunogenes hybridprotein oprf-oprl erhältlich aus membranproteinen von pseudomonas aeruginosa
US5981227A (en) * 1995-02-09 1999-11-09 Movartis Ag Process for the production of proteins

Also Published As

Publication number Publication date
PT801682E (pt) 2002-03-28
DE69616276T2 (de) 2002-12-12
AU707657B2 (en) 1999-07-15
WO1996024678A1 (en) 1996-08-15
JP3732516B2 (ja) 2006-01-05
ATE207538T1 (de) 2001-11-15
EP0801682B1 (en) 2001-10-24
AU4487496A (en) 1996-08-27
US6284520B1 (en) 2001-09-04
US5981227A (en) 1999-11-09
EP0801682A1 (en) 1997-10-22
JPH10513353A (ja) 1998-12-22
DK0801682T3 (da) 2002-02-18
DE69616276D1 (de) 2001-11-29

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