JP2004529602A5 - - Google Patents
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- Publication number
- JP2004529602A5 JP2004529602A5 JP2001561782A JP2001561782A JP2004529602A5 JP 2004529602 A5 JP2004529602 A5 JP 2004529602A5 JP 2001561782 A JP2001561782 A JP 2001561782A JP 2001561782 A JP2001561782 A JP 2001561782A JP 2004529602 A5 JP2004529602 A5 JP 2004529602A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- nucleic acid
- endonuclease
- seq
- polynucleotide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000007523 nucleic acids Chemical class 0.000 description 18
- 102000004533 Endonucleases Human genes 0.000 description 16
- 108010042407 Endonucleases Proteins 0.000 description 16
- 102000039446 nucleic acids Human genes 0.000 description 16
- 108020004707 nucleic acids Proteins 0.000 description 16
- 108091033319 polynucleotide Proteins 0.000 description 15
- 102000040430 polynucleotide Human genes 0.000 description 15
- 239000002157 polynucleotide Substances 0.000 description 15
- 238000000034 method Methods 0.000 description 11
- 230000035772 mutation Effects 0.000 description 10
- 230000000694 effects Effects 0.000 description 9
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 108090000623 proteins and genes Proteins 0.000 description 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 4
- 108020004414 DNA Proteins 0.000 description 4
- 240000007087 Apium graveolens Species 0.000 description 3
- 235000015849 Apium graveolens Dulce Group Nutrition 0.000 description 3
- 235000010591 Appio Nutrition 0.000 description 3
- 241000196324 Embryophyta Species 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 239000002299 complementary DNA Substances 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 239000002773 nucleotide Substances 0.000 description 2
- 125000003729 nucleotide group Chemical group 0.000 description 2
- 101100065298 Arabidopsis thaliana ENDO1 gene Proteins 0.000 description 1
- 102000053602 DNA Human genes 0.000 description 1
- 101100107108 Drosophila melanogaster zen gene Proteins 0.000 description 1
- 241000238631 Hexapoda Species 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 108010044467 Isoenzymes Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 108091028043 Nucleic acid sequence Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 239000013612 plasmid Substances 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 238000003259 recombinant expression Methods 0.000 description 1
- 230000001177 retroviral effect Effects 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/510,322 US6391557B1 (en) | 2000-02-22 | 2000-02-22 | Nucleic acid molecule encoding a mismatch endonuclease and methods of use thereof |
| US09/510,322 | 2000-02-22 | ||
| US09/514,768 | 2000-02-28 | ||
| US09/514,768 US6699980B1 (en) | 2000-02-28 | 2000-02-28 | Nucleic acid molecule encoding a mismatch endonuclease and methods of use thereof |
| PCT/US2001/005502 WO2001062974A1 (en) | 2000-02-22 | 2001-02-22 | Nucleic acid molecule encoding a mismatch endonuclease and methods of use thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004529602A JP2004529602A (ja) | 2004-09-30 |
| JP2004529602A5 true JP2004529602A5 (enExample) | 2008-04-10 |
| JP4986358B2 JP4986358B2 (ja) | 2012-07-25 |
Family
ID=27056866
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001561782A Expired - Fee Related JP4986358B2 (ja) | 2000-02-22 | 2001-02-22 | ミスマッチエンドヌクレアーゼをコードする核酸分子およびその使用方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1257671B1 (enExample) |
| JP (1) | JP4986358B2 (enExample) |
| AU (2) | AU4721201A (enExample) |
| CA (1) | CA2400441C (enExample) |
| WO (1) | WO2001062974A1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7838219B2 (en) | 2001-02-02 | 2010-11-23 | Novici Biotech Llc | Method of increasing complementarity in a heteroduplex |
| WO2002079468A2 (en) | 2001-02-02 | 2002-10-10 | Large Scale Biology Corporation | A method of increasing complementarity in a heteroduplex polynucleotide |
| US7582423B2 (en) | 2001-02-02 | 2009-09-01 | Novici Biotech Llc | Population of polynucleotide sequence variants |
| US7078211B2 (en) | 2002-02-01 | 2006-07-18 | Large Scale Biology Corporation | Nucleic acid molecules encoding endonucleases and methods of use thereof |
| DE10248258A1 (de) * | 2002-10-16 | 2004-05-06 | Biopsytec Analytik Gmbh | Mutierte Nukleinsäure einer Cel I-Endonuklease und Verfahren zur Herstellung des rekombinanten vollständigen Cel I-Proteins |
| ATE495243T1 (de) * | 2004-07-30 | 2011-01-15 | Genoplante Valor | Verfahren zur herstellung von hochempfindlichen endonukleasen, neuartige zubereitungen von nukleasen und ihre verwendung |
| CN101538561B (zh) * | 2009-04-17 | 2010-09-29 | 广州大学 | 一种提取芹菜中celⅰ核酸酶的方法 |
| KR102126744B1 (ko) | 2013-03-14 | 2020-06-26 | 다카라 바이오 가부시키가이샤 | 내열성 미스매치 엔도뉴클레아제의 이용방법 |
| KR20170053636A (ko) * | 2014-09-11 | 2017-05-16 | 다카라 바이오 가부시키가이샤 | 내열성의 미스매치 엔도뉴클레아제의 이용방법 |
| US11845928B2 (en) | 2015-05-04 | 2023-12-19 | Tsinghua University | Methods and kits for fragmenting DNA |
| JP7734380B2 (ja) | 2020-03-19 | 2025-09-05 | タカラバイオ株式会社 | 耐熱性ミスマッチエンドヌクレアーゼ変異体 |
| CN112301020B (zh) * | 2020-10-19 | 2024-04-12 | 复旦大学附属肿瘤医院 | Iii类脱氧核酶突变体及其制备方法与应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997046701A1 (en) * | 1996-06-05 | 1997-12-11 | Fox Chase Cancer Center | Mismatch endonucleases and uses thereof in identifying mutations in targeted polynucleotide strands |
| US5869245A (en) * | 1996-06-05 | 1999-02-09 | Fox Chase Cancer Center | Mismatch endonuclease and its use in identifying mutations in targeted polynucleotide strands |
-
2001
- 2001-02-22 AU AU4721201A patent/AU4721201A/xx active Pending
- 2001-02-22 WO PCT/US2001/005502 patent/WO2001062974A1/en not_active Ceased
- 2001-02-22 AU AU2001247212A patent/AU2001247212B2/en not_active Ceased
- 2001-02-22 EP EP01920126.8A patent/EP1257671B1/en not_active Expired - Lifetime
- 2001-02-22 JP JP2001561782A patent/JP4986358B2/ja not_active Expired - Fee Related
- 2001-02-22 CA CA2400441A patent/CA2400441C/en not_active Expired - Lifetime
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