JP2000201677A5 - - Google Patents
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- Publication number
- JP2000201677A5 JP2000201677A5 JP1999306628A JP30662899A JP2000201677A5 JP 2000201677 A5 JP2000201677 A5 JP 2000201677A5 JP 1999306628 A JP1999306628 A JP 1999306628A JP 30662899 A JP30662899 A JP 30662899A JP 2000201677 A5 JP2000201677 A5 JP 2000201677A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- nucleotides
- repeat region
- oligonucleotide primer
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002773 nucleotide Substances 0.000 description 46
- 125000003729 nucleotide group Chemical group 0.000 description 46
- 239000013615 primer Substances 0.000 description 36
- 108091034117 Oligonucleotide Proteins 0.000 description 24
- 238000000034 method Methods 0.000 description 24
- 108020004414 DNA Proteins 0.000 description 23
- 230000000295 complement effect Effects 0.000 description 18
- 201000003629 Spinocerebellar ataxia type 8 Diseases 0.000 description 17
- 108020004707 nucleic acids Proteins 0.000 description 16
- 102000039446 nucleic acids Human genes 0.000 description 16
- 150000007523 nucleic acids Chemical class 0.000 description 16
- 239000012634 fragment Substances 0.000 description 15
- 108091026890 Coding region Proteins 0.000 description 11
- 102000053602 DNA Human genes 0.000 description 8
- 239000000523 sample Substances 0.000 description 8
- 239000002299 complementary DNA Substances 0.000 description 5
- 108020004635 Complementary DNA Proteins 0.000 description 4
- 239000003155 DNA primer Substances 0.000 description 3
- 230000002194 synthesizing effect Effects 0.000 description 3
- 108700028369 Alleles Proteins 0.000 description 2
- 238000010804 cDNA synthesis Methods 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 102000014461 Ataxins Human genes 0.000 description 1
- 108010078286 Ataxins Proteins 0.000 description 1
- 206010008025 Cerebellar ataxia Diseases 0.000 description 1
- 208000009415 Spinocerebellar Ataxias Diseases 0.000 description 1
- 201000004562 autosomal dominant cerebellar ataxia Diseases 0.000 description 1
- 210000000349 chromosome Anatomy 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000005215 recombination Methods 0.000 description 1
- 230000006798 recombination Effects 0.000 description 1
- 108091008146 restriction endonucleases Proteins 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/181585 | 1998-10-28 | ||
| US09/181,585 US6524791B1 (en) | 1998-10-28 | 1998-10-28 | Spinocerebellar ataxia type 8 and methods of detection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000201677A JP2000201677A (ja) | 2000-07-25 |
| JP2000201677A5 true JP2000201677A5 (enExample) | 2006-08-03 |
| JP4637982B2 JP4637982B2 (ja) | 2011-02-23 |
Family
ID=22664902
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP30662899A Expired - Lifetime JP4637982B2 (ja) | 1998-10-28 | 1999-10-28 | ８型脊髄小脳性運動失調及び検査方法 |
Country Status (3)
| Country | Link |
|---|---|
| US (5) | US6524791B1 (enExample) |
| JP (1) | JP4637982B2 (enExample) |
| CA (1) | CA2283758C (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6514755B1 (en) * | 1998-08-18 | 2003-02-04 | Regents Of The University Of Minnesota | SCA7 gene and methods of use |
| US6524791B1 (en) * | 1998-10-28 | 2003-02-25 | Regents Of The University Of Minnesota | Spinocerebellar ataxia type 8 and methods of detection |
| KR20030013019A (ko) * | 2001-08-06 | 2003-02-14 | 주식회사 바이오메드랩 | 삼핵산 반복서열 증가질환용 진단키트 및 진단장치 |
| US8963713B2 (en) | 2005-03-16 | 2015-02-24 | Icontrol Networks, Inc. | Integrated security network with security alarm signaling system |
| JP5716217B2 (ja) * | 2009-12-15 | 2015-05-13 | 公益財団法人ヒューマンサイエンス振興財団 | 長鎖繰返し配列を含有する遺伝子又は遺伝子産物の選択又は優先的回収方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4683194A (en) | 1984-05-29 | 1987-07-28 | Cetus Corporation | Method for detection of polymorphic restriction sites and nucleic acid sequences |
| US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US5558988A (en) * | 1992-11-13 | 1996-09-24 | Thomas Jefferson University | Primers and methods for detecting mutations in the procollagen II gene that indicate a genetic predisposition for osteoarthritis |
| US5695933A (en) * | 1993-05-28 | 1997-12-09 | Massachusetts Institute Of Technology | Direct detection of expanded nucleotide repeats in the human genome |
| US5741645A (en) | 1993-06-29 | 1998-04-21 | Regents Of The University Of Minnesota | Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis |
| US5834183A (en) | 1993-06-29 | 1998-11-10 | Regents Of The University Of Minnesota | Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis |
| WO1997042314A1 (en) | 1996-05-08 | 1997-11-13 | Cedars-Sinai Medical Center | Nucleic acid encoding spinocerebellar ataxia-2 and products related thereto |
| US5807743A (en) * | 1996-12-03 | 1998-09-15 | Ribozyme Pharmaceuticals, Inc. | Interleukin-2 receptor gamma-chain ribozymes |
| US6280938B1 (en) | 1997-08-19 | 2001-08-28 | Regents Of The University Of Minnesota | SCA7 gene and method of use |
| US6183953B1 (en) * | 1997-09-15 | 2001-02-06 | Zymogenetics, Inc. | Chromosomal mutagenesis in Pichia methanolica |
| US6524791B1 (en) | 1998-10-28 | 2003-02-25 | Regents Of The University Of Minnesota | Spinocerebellar ataxia type 8 and methods of detection |
-
1998
- 1998-10-28 US US09/181,585 patent/US6524791B1/en not_active Expired - Lifetime
-
1999
- 1999-09-27 CA CA2283758A patent/CA2283758C/en not_active Expired - Lifetime
- 1999-10-28 JP JP30662899A patent/JP4637982B2/ja not_active Expired - Lifetime
-
2003
- 2003-02-24 US US10/373,667 patent/US7741458B2/en not_active Expired - Fee Related
-
2010
- 2010-06-21 US US12/819,749 patent/US8247173B2/en not_active Expired - Fee Related
-
2012
- 2012-08-20 US US13/589,266 patent/US8748096B2/en not_active Expired - Fee Related
-
2014
- 2014-04-28 US US14/263,064 patent/US9556488B2/en not_active Expired - Fee Related
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