JP2001514013A5 - - Google Patents
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- Publication number
- JP2001514013A5 JP2001514013A5 JP2000507836A JP2000507836A JP2001514013A5 JP 2001514013 A5 JP2001514013 A5 JP 2001514013A5 JP 2000507836 A JP2000507836 A JP 2000507836A JP 2000507836 A JP2000507836 A JP 2000507836A JP 2001514013 A5 JP2001514013 A5 JP 2001514013A5
- Authority
- JP
- Japan
- Prior art keywords
- ltc
- synthase gene
- polymorphism
- single nucleotide
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000000034 method Methods 0.000 description 9
- 239000002773 nucleotide Substances 0.000 description 9
- 125000003729 nucleotide group Chemical group 0.000 description 9
- 108090000623 proteins and genes Proteins 0.000 description 8
- 108700028369 Alleles Proteins 0.000 description 3
- 108020004707 nucleic acids Proteins 0.000 description 3
- 150000007523 nucleic acids Chemical class 0.000 description 3
- 102000039446 nucleic acids Human genes 0.000 description 3
- 238000009007 Diagnostic Kit Methods 0.000 description 1
- 108091026898 Leader sequence (mRNA) Proteins 0.000 description 1
- 108091034117 Oligonucleotide Proteins 0.000 description 1
- 108020005187 Oligonucleotide Probes Proteins 0.000 description 1
- 230000003321 amplification Effects 0.000 description 1
- 238000003199 nucleic acid amplification method Methods 0.000 description 1
- 239000002751 oligonucleotide probe Substances 0.000 description 1
- 238000007894 restriction fragment length polymorphism technique Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9717766.1A GB9717766D0 (en) | 1997-08-22 | 1997-08-22 | Methods |
| GB9717766.1 | 1997-08-22 | ||
| PCT/GB1998/002468 WO1999010529A1 (en) | 1997-08-22 | 1998-08-18 | Methods for analyzing ltc4 synthase polymorphisms and diagnostic use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001514013A JP2001514013A (ja) | 2001-09-11 |
| JP2001514013A5 true JP2001514013A5 (enExample) | 2006-01-05 |
Family
ID=10817852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000507836A Pending JP2001514013A (ja) | 1997-08-22 | 1998-08-18 | Ltc4シンターゼ多型の分析方法および診断への利用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US6316196B1 (enExample) |
| EP (1) | EP1007738A1 (enExample) |
| JP (1) | JP2001514013A (enExample) |
| AU (1) | AU8814798A (enExample) |
| GB (2) | GB9717766D0 (enExample) |
| WO (1) | WO1999010529A1 (enExample) |
Families Citing this family (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6881571B1 (en) | 1998-03-11 | 2005-04-19 | Exonhit Therapeutics S.A. | Qualitative differential screening |
| FR2798392B1 (fr) * | 1999-09-13 | 2005-07-15 | Exonhit Therapeutics Sa | Marqueurs genetiques de la toxicite, preparation et utilisations |
| AU3793701A (en) * | 1999-11-29 | 2001-06-04 | Orchid Biosciences, Inc. | Methods of identifying optimal drug combinations and compositions thereof |
| WO2001079560A2 (en) * | 2000-04-17 | 2001-10-25 | Glaxo Group Limited | Medicine response assay in respiratory disease |
| CN1329012A (zh) * | 2000-06-21 | 2002-01-02 | 上海博德基因开发有限公司 | 一种新的多肽——烟酰胺腺嘌呤脱氧二核苷酸依赖性白三烯b412-羟基脱氢酶36和编码这种多肽的多核甘酸 |
| US20050009023A1 (en) * | 2001-07-03 | 2005-01-13 | Neil Richtand | Glucocorticoid-induced receptor and methods of use |
| CA2458303A1 (en) * | 2001-09-17 | 2003-03-27 | Janssen Pharmaceutica N.V. | Brain expressed cap-2 gene and protein associated with bipolar disorder |
| US7833706B2 (en) * | 2003-01-30 | 2010-11-16 | Celera Corporation | Genetic polymorphisms associated with rheumatoid arthritis, methods of detection and uses thereof |
| US20050019795A1 (en) * | 2003-04-24 | 2005-01-27 | Aventis Pharma Deutschland Gmbh | Analysis and use of PAR1 polymorphisms for evaluating the risk of cardiovascular disorders |
| EP2186913B1 (en) * | 2003-11-26 | 2016-02-10 | Celera Corporation | Genetic polymorphisms associated with cardiovascular disorders and drug response, methods of detection and uses thereof |
| US20090297563A1 (en) * | 2004-10-27 | 2009-12-03 | Anders Borglum | Diagnosis And Treatment of Immune-Related Diseases |
| WO2007059348A2 (en) * | 2005-11-17 | 2007-05-24 | Third Wave Technologies, Inc. | Compositions and methods for detecting an hcv-1 subtype |
| EP2027284A2 (en) * | 2006-05-18 | 2009-02-25 | Sanofi-Aventis | Use of adamts4 gene and protein polymorphisms |
| CA2653794C (en) * | 2006-06-30 | 2012-05-01 | Clifford L. Librach | Method of detecting preeclampsia |
| WO2008033239A2 (en) * | 2006-09-11 | 2008-03-20 | Applera | Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof |
| WO2008039941A2 (en) | 2006-09-27 | 2008-04-03 | The Government Of The Usa As Represented By The Secretary Of The Dpt. Of Health And Human Services | Scgb3a2 as a growth factor and anti-apoptotic agent |
| US7811765B2 (en) * | 2006-10-12 | 2010-10-12 | Children's Hospital & Research Center At Oakland | Methods and compositions for determining predisposition to inflammation-mediated cardiovascular disease |
| US20080248470A1 (en) * | 2007-04-04 | 2008-10-09 | Sungkyunkwan University Foundation For Corporate Collaboration | Genetic screening for predicting antidepressant drug response based on the monoamine transporter gene polymorphism combination |
| US9079961B2 (en) * | 2007-05-25 | 2015-07-14 | Japanese Red Cross Society | GPIIIa gene |
| WO2009052160A1 (en) * | 2007-10-19 | 2009-04-23 | Marshfield Clinic | Method for administering anticoagulation therapy |
| WO2009061734A1 (en) * | 2007-11-05 | 2009-05-14 | The Government Of The United States Of America As Represented By The Secretary Of The Deparment Of Health And Human Services | Identification of subjects likely to benefit from statin therapy |
| US7947451B2 (en) * | 2007-11-30 | 2011-05-24 | Celera Corporation | Genetic polymorphisms associated with psoriasis, methods of detection and uses thereof |
| US10023913B2 (en) * | 2008-01-29 | 2018-07-17 | The Johns Hopkins University | SR-BI as a predictor of elevated high density lipoprotein and cardiovascular disease |
| US20110112186A1 (en) * | 2008-02-29 | 2011-05-12 | Isis Innovation Limited | Diagnostic methods |
| US9817001B2 (en) | 2008-05-27 | 2017-11-14 | Boston Heart Diagnostics Corporation | Methods for determining LDL cholesterol treatment |
| US8470541B1 (en) | 2008-09-27 | 2013-06-25 | Boston Heart Diagnostics Corporation | Methods for separation and immuno-detection of biomolecules, and apparatus related thereto |
| DE102008064509B4 (de) * | 2008-12-22 | 2017-06-08 | Robert Bosch Gesellschaft mbH für medizinische Forschung | Verfahren zur Bestimmung der Prädisposition für Morbus Crohn |
| CA2706021C (en) * | 2009-05-28 | 2018-10-16 | Institut De Cardiologie De Montreal | Genetic predictors of international normalized ratio (inr) fluctuation with warfarin therapy |
| WO2011068610A1 (en) * | 2009-12-01 | 2011-06-09 | Quest Diagnostics Investments Incorporated | Methods for detecting risk of myelodysplastic syndrome by genotypic analysis |
| US9732389B2 (en) | 2010-09-03 | 2017-08-15 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with prostate cancer risk |
| WO2012082912A2 (en) * | 2010-12-14 | 2012-06-21 | Tufts Medical Center, Inc. | Markers related to age-related macular degeneration and uses therefor |
| US9534256B2 (en) * | 2011-01-06 | 2017-01-03 | Wake Forest University Health Sciences | Methods and compositions for correlating genetic markers with risk of aggressive prostate cancer |
| AU2012322018B2 (en) | 2011-10-13 | 2017-09-21 | Boston Heart Diagnostics | Compositions and methods for treating and preventing coronary heart disease |
| US9828624B2 (en) | 2013-07-24 | 2017-11-28 | Boston Heart Diagnostics Corporation | Driving patient compliance with therapy |
| US10098893B2 (en) * | 2013-10-03 | 2018-10-16 | Northwestern University | Methods of administering a trace amine-associated receptor 1 (TAAR1) agonist to patients having the minor allele of the single nucleotide polymorphism rs2237457 |
| EP3149487B1 (en) * | 2014-05-29 | 2020-02-12 | Geneticure LLC | Improved therapeutic regimen for hypertension |
| US11761043B2 (en) | 2014-05-29 | 2023-09-19 | Geneticure Inc. | Machine assay and analysis for selecting antihypertensive drugs |
| US10260108B2 (en) * | 2014-11-04 | 2019-04-16 | University of Pittsburgh—of the Commonwealth System of Higher Education | PARP genomic variants conferring resistance and sensitization to chemotherapy under inhibition |
| CA2968221A1 (en) | 2014-11-17 | 2016-05-26 | Boston Heart Diagnostic Corporation | Cardiovascular disease risk assessment |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993018178A1 (en) * | 1992-03-13 | 1993-09-16 | The Children's Hospital Of Philadelphia | DIAGNOSIS OF β-THALASSEMIA USING A MULTIPLEX AMPLIFICATION REFRACTORY MUTATION SYSTEM |
| CA2136239C (en) | 1992-06-15 | 2004-10-05 | Donald W. Nicholson | Leukotriene c4 synthase |
| WO1995032280A1 (en) * | 1994-05-20 | 1995-11-30 | Brigham And Women's Hospital | Dna encoding human leukotriene c4 synthase, polypeptides, and uses therefor |
| US5952210A (en) * | 1994-06-03 | 1999-09-14 | G. D. Searle & Company | Nucleic acids and expression vectors encoding human leukotiene C4 synthase |
| AU2927797A (en) | 1996-05-06 | 1997-11-26 | Brigham And Women's Hospital | 5-lipoxygenase gene polymorphisms and their use in classifying patients |
-
1997
- 1997-08-22 GB GBGB9717766.1A patent/GB9717766D0/en active Pending
-
1998
- 1998-08-18 EP EP98939738A patent/EP1007738A1/en not_active Withdrawn
- 1998-08-18 GB GB0001527A patent/GB2342717B/en not_active Expired - Fee Related
- 1998-08-18 US US09/485,636 patent/US6316196B1/en not_active Expired - Fee Related
- 1998-08-18 JP JP2000507836A patent/JP2001514013A/ja active Pending
- 1998-08-18 WO PCT/GB1998/002468 patent/WO1999010529A1/en not_active Ceased
- 1998-08-18 AU AU88147/98A patent/AU8814798A/en not_active Abandoned
-
2001
- 2001-10-31 US US09/984,842 patent/US20030077592A1/en not_active Abandoned
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