JP2005528910A5 - - Google Patents

Info

Publication number

JP2005528910A5

JP2005528910A5 JP2004511467A JP2004511467A JP2005528910A5 JP 2005528910 A5 JP2005528910 A5 JP 2005528910A5 JP 2004511467 A JP2004511467 A JP 2004511467A JP 2004511467 A JP2004511467 A JP 2004511467A JP 2005528910 A5 JP2005528910 A5 JP 2005528910A5

Authority

JP

Japan

Prior art keywords

seq

sequence

oligonucleotide

group

nucleotides

Prior art date

2003-06-05

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 108091034117 Oligonucleotide Proteins 0.000 claims 23
• 239000002773 nucleotide Substances 0.000 claims 18
• 125000003729 nucleotide group Chemical group 0.000 claims 18
• 108020004707 nucleic acids Proteins 0.000 claims 11
• 150000007523 nucleic acids Chemical class 0.000 claims 11
• 102000039446 nucleic acids Human genes 0.000 claims 11
• 108700042075 T-Cell Receptor Genes Proteins 0.000 claims 8
• 210000001744 T-lymphocyte Anatomy 0.000 claims 8
• 238000000034 method Methods 0.000 claims 7
• 230000000295 complement effect Effects 0.000 claims 5
• 108090000765 processed proteins & peptides Proteins 0.000 claims 5
• 239000000523 sample Substances 0.000 claims 5
• YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims 4
• 108020005187 Oligonucleotide Probes Proteins 0.000 claims 4
• 239000002751 oligonucleotide probe Substances 0.000 claims 4
• 229960005486 vaccine Drugs 0.000 claims 4
• 108091008874 T cell receptors Proteins 0.000 claims 3
• 102000016266 T-Cell Antigen Receptors Human genes 0.000 claims 3
• 238000002372 labelling Methods 0.000 claims 3
• 208000023275 Autoimmune disease Diseases 0.000 claims 2
• SHIBSTMRCDJXLN-UHFFFAOYSA-N Digoxigenin Natural products C1CC(C2C(C3(C)CCC(O)CC3CC2)CC2O)(O)C2(C)C1C1=CC(=O)OC1 SHIBSTMRCDJXLN-UHFFFAOYSA-N 0.000 claims 2
• 229960002685 biotin Drugs 0.000 claims 2
• 235000020958 biotin Nutrition 0.000 claims 2
• 239000011616 biotin Substances 0.000 claims 2
• QONQRTHLHBTMGP-UHFFFAOYSA-N digitoxigenin Natural products CC12CCC(C3(CCC(O)CC3CC3)C)C3C11OC1CC2C1=CC(=O)OC1 QONQRTHLHBTMGP-UHFFFAOYSA-N 0.000 claims 2
• SHIBSTMRCDJXLN-KCZCNTNESA-N digoxigenin Chemical compound C1([C@@H]2[C@@]3([C@@](CC2)(O)[C@H]2[C@@H]([C@@]4(C)CC[C@H](O)C[C@H]4CC2)C[C@H]3O)C)=CC(=O)OC1 SHIBSTMRCDJXLN-KCZCNTNESA-N 0.000 claims 2
• 239000003937 drug carrier Substances 0.000 claims 2
• 238000003752 polymerase chain reaction Methods 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 238000000376 autoradiography Methods 0.000 claims 1
• 238000001514 detection method Methods 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 238000012544 monitoring process Methods 0.000 claims 1