CA2283758C - Spinocerebellar ataxia type 8 and methods of detection - Google Patents

Spinocerebellar ataxia type 8 and methods of detection Download PDF

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Publication number
CA2283758C
CA2283758C CA2283758A CA2283758A CA2283758C CA 2283758 C CA2283758 C CA 2283758C CA 2283758 A CA2283758 A CA 2283758A CA 2283758 A CA2283758 A CA 2283758A CA 2283758 C CA2283758 C CA 2283758C
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CA
Canada
Prior art keywords
seq
nucleotides
repeat region
ctg
repeat
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2283758A
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English (en)
French (fr)
Other versions
CA2283758A1 (en
Inventor
Laura P.W. Ranum
Michael D. Koob
Kellie A. Benzow
Melinda L. Moseley-Alldredge
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University of Minnesota System
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University of Minnesota System
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Publication date
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Publication of CA2283758A1 publication Critical patent/CA2283758A1/en
Application granted granted Critical
Publication of CA2283758C publication Critical patent/CA2283758C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2283758A 1998-10-28 1999-09-27 Spinocerebellar ataxia type 8 and methods of detection Expired - Lifetime CA2283758C (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/181,585 1998-10-28
US09/181,585 US6524791B1 (en) 1998-10-28 1998-10-28 Spinocerebellar ataxia type 8 and methods of detection

Publications (2)

Publication Number Publication Date
CA2283758A1 CA2283758A1 (en) 2000-04-28
CA2283758C true CA2283758C (en) 2011-05-10

Family

ID=22664902

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2283758A Expired - Lifetime CA2283758C (en) 1998-10-28 1999-09-27 Spinocerebellar ataxia type 8 and methods of detection

Country Status (3)

Country Link
US (5) US6524791B1 (enExample)
JP (1) JP4637982B2 (enExample)
CA (1) CA2283758C (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6514755B1 (en) * 1998-08-18 2003-02-04 Regents Of The University Of Minnesota SCA7 gene and methods of use
US6524791B1 (en) 1998-10-28 2003-02-25 Regents Of The University Of Minnesota Spinocerebellar ataxia type 8 and methods of detection
KR20030013019A (ko) * 2001-08-06 2003-02-14 주식회사 바이오메드랩 삼핵산 반복서열 증가질환용 진단키트 및 진단장치
US8963713B2 (en) 2005-03-16 2015-02-24 Icontrol Networks, Inc. Integrated security network with security alarm signaling system
JP5716217B2 (ja) * 2009-12-15 2015-05-13 公益財団法人ヒューマンサイエンス振興財団 長鎖繰返し配列を含有する遺伝子又は遺伝子産物の選択又は優先的回収方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683194A (en) 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US5558988A (en) * 1992-11-13 1996-09-24 Thomas Jefferson University Primers and methods for detecting mutations in the procollagen II gene that indicate a genetic predisposition for osteoarthritis
US5695933A (en) * 1993-05-28 1997-12-09 Massachusetts Institute Of Technology Direct detection of expanded nucleotide repeats in the human genome
US5834183A (en) 1993-06-29 1998-11-10 Regents Of The University Of Minnesota Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis
US5741645A (en) 1993-06-29 1998-04-21 Regents Of The University Of Minnesota Gene sequence for spinocerebellar ataxia type 1 and method for diagnosis
WO1997042314A1 (en) 1996-05-08 1997-11-13 Cedars-Sinai Medical Center Nucleic acid encoding spinocerebellar ataxia-2 and products related thereto
US5807743A (en) * 1996-12-03 1998-09-15 Ribozyme Pharmaceuticals, Inc. Interleukin-2 receptor gamma-chain ribozymes
US6280938B1 (en) 1997-08-19 2001-08-28 Regents Of The University Of Minnesota SCA7 gene and method of use
US6183953B1 (en) * 1997-09-15 2001-02-06 Zymogenetics, Inc. Chromosomal mutagenesis in Pichia methanolica
US6524791B1 (en) 1998-10-28 2003-02-25 Regents Of The University Of Minnesota Spinocerebellar ataxia type 8 and methods of detection

Also Published As

Publication number Publication date
JP2000201677A (ja) 2000-07-25
US20030235841A1 (en) 2003-12-25
US6524791B1 (en) 2003-02-25
JP4637982B2 (ja) 2011-02-23
CA2283758A1 (en) 2000-04-28
US7741458B2 (en) 2010-06-22
US8247173B2 (en) 2012-08-21
US20140322711A1 (en) 2014-10-30
US9556488B2 (en) 2017-01-31
US20130029335A1 (en) 2013-01-31
US8748096B2 (en) 2014-06-10
US20100317015A1 (en) 2010-12-16
US20130230849A9 (en) 2013-09-05

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Effective date: 20190927