JP2004528809A5 - - Google Patents
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- Publication number
- JP2004528809A5 JP2004528809A5 JP2002532629A JP2002532629A JP2004528809A5 JP 2004528809 A5 JP2004528809 A5 JP 2004528809A5 JP 2002532629 A JP2002532629 A JP 2002532629A JP 2002532629 A JP2002532629 A JP 2002532629A JP 2004528809 A5 JP2004528809 A5 JP 2004528809A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- sequence seq
- consensus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 125000003275 alpha amino acid group Chemical group 0.000 description 10
- 101001130247 Homo sapiens Reticulon-4 receptor-like 2 Proteins 0.000 description 4
- 101001130249 Mus musculus Reticulon-4 receptor-like 1 Proteins 0.000 description 4
- 102000053414 human RTN4RL2 Human genes 0.000 description 4
- 102000000343 Nogo Receptor 1 Human genes 0.000 description 2
- 108010041199 Nogo Receptor 1 Proteins 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 239000002299 complementary DNA Substances 0.000 description 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 1
- 108091035707 Consensus sequence Proteins 0.000 description 1
- 101001130250 Homo sapiens Reticulon-4 receptor-like 1 Proteins 0.000 description 1
- 102000010410 Nogo Proteins Human genes 0.000 description 1
- 108010077641 Nogo Proteins Proteins 0.000 description 1
- 101710095853 Reticulon-4 receptor-like 1 Proteins 0.000 description 1
- 102100031540 Reticulon-4 receptor-like 1 Human genes 0.000 description 1
- 125000000539 amino acid group Chemical group 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23836100P | 2000-10-06 | 2000-10-06 | |
| PCT/US2001/031488 WO2002029059A2 (en) | 2000-10-06 | 2001-10-06 | Nogo receptor homologs |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009022063A Division JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004528809A JP2004528809A (ja) | 2004-09-24 |
| JP2004528809A5 true JP2004528809A5 (enExample) | 2005-03-03 |
| JP4465148B2 JP4465148B2 (ja) | 2010-05-19 |
Family
ID=22897532
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002532629A Expired - Fee Related JP4465148B2 (ja) | 2000-10-06 | 2001-10-06 | Ｎｏｇｏレセプターホモログ |
| JP2009022063A Withdrawn JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009022063A Withdrawn JP2009100767A (ja) | 2000-10-06 | 2009-02-02 | Ｎｏｇｏレセプターホモログ |
Country Status (12)
| Country | Link |
|---|---|
| US (5) | US20030124704A1 (enExample) |
| EP (1) | EP1325130B1 (enExample) |
| JP (2) | JP4465148B2 (enExample) |
| AT (1) | ATE458815T1 (enExample) |
| AU (2) | AU1153902A (enExample) |
| CA (1) | CA2424834A1 (enExample) |
| DE (1) | DE60141409D1 (enExample) |
| DK (1) | DK1325130T3 (enExample) |
| ES (1) | ES2341608T3 (enExample) |
| NZ (1) | NZ525422A (enExample) |
| PT (1) | PT1325130E (enExample) |
| WO (1) | WO2002029059A2 (enExample) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7119165B2 (en) * | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| ES2341608T3 (es) * | 2000-10-06 | 2010-06-23 | Yale University | Homologos del receptor de nogo. |
| WO2003018631A2 (en) * | 2001-08-27 | 2003-03-06 | Novartis Ag | Nogo receptor homologues and their use |
| JP2005519584A (ja) * | 2001-10-22 | 2005-07-07 | ノバルティス アクチエンゲゼルシャフト | Ｎｏｇｏレセプターホモログおよびそれらの使用 |
| US7309485B2 (en) * | 2001-12-03 | 2007-12-18 | Children's Medical Center Corporation | Reducing myelin-mediated inhibition of axon regeneration |
| AU2003246254A1 (en) * | 2002-07-05 | 2004-01-23 | Shionogi And Co., Ltd. | NOVEL Nogo RECEPTOR-LIKE POLYPEPTIDE AND DNA THEREOF |
| CA2495121A1 (en) * | 2002-08-10 | 2004-02-19 | Yale University | Nogo receptor antagonists |
| EP2902491A1 (en) | 2003-03-19 | 2015-08-05 | Biogen MA Inc. | NOGO receptor binding protein |
| EP1623036A4 (en) * | 2003-04-04 | 2007-06-20 | Univ Rochester | IDENTIFICATION OF NEW NOGO RECEPTORS AND ASSOCIATED METHODS |
| MXPA05011100A (es) * | 2003-04-16 | 2006-04-18 | Univ Yale | Antagonistas de receptor nogo para el tratamiento de condiciones que comprenden placas amiloideas. |
| EA008253B1 (ru) * | 2003-08-07 | 2007-04-27 | Байоджен Айдек Ма Инк. | Антагонисты nogo-рецептора |
| EP1695061A4 (en) * | 2003-12-16 | 2008-02-20 | Childrens Medical Center | METHOD OF TREATING NEUROLOGICAL DISORDERS |
| US8912144B2 (en) * | 2003-12-16 | 2014-12-16 | Children's Medical Center Corporation | Method for treating stroke via administration of NEP1-40 and inosine |
| CN1946418A (zh) * | 2004-01-30 | 2007-04-11 | 比奥根艾迪克Ma公司 | 利用nogo受体拮抗剂治疗涉及多巴胺能神经元退变的疾病 |
| EP1776136B1 (en) | 2004-06-24 | 2012-10-03 | Biogen Idec MA Inc. | Treatment of conditions involving demyelination |
| JP2008515804A (ja) * | 2004-10-01 | 2008-05-15 | イェール ユニバーシティ | Ｎｏｇｏ−Ａポリペプチド断片、改変体Ｎｏｇｏレセプター１ポリペプチドおよびそれらの使用 |
| EP1904091A4 (en) * | 2005-07-07 | 2009-12-23 | Univ Yale | COMPOSITIONS AND METHODS FOR SUPPRESSING THE INHIBITION OF AXON GROWTH |
| AU2006269458B2 (en) | 2005-07-08 | 2012-11-08 | Biogen Ma Inc. | Sp35 antibodies and uses thereof |
| JP2009505665A (ja) * | 2005-08-25 | 2009-02-12 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Ｎｏｇｏ受容体ポリペプチドおよびポリペプチドフラグメント、ならびにそれらの使用 |
| JP5829373B2 (ja) | 2006-01-27 | 2015-12-09 | バイオジェン・エムエイ・インコーポレイテッドＢｉｏｇｅｎ ＭＡ Ｉｎｃ． | Ｎｏｇｏレセプターアンタゴニスト |
| JP2009538282A (ja) * | 2006-05-15 | 2009-11-05 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 乏突起膠細胞の生存を促進させるためのＮｏｇｏ受容体−１（ＮｇＲ１）アンタゴニストの使用 |
| WO2007137303A2 (en) * | 2006-05-24 | 2007-11-29 | Myelin Repair Foundation, Inc. | Permeability of blood-brain barrier |
| US20100047232A1 (en) * | 2006-11-14 | 2010-02-25 | Jasvinder Atwal | Modulators of neuronal regeneration |
| AU2007319359A1 (en) | 2006-11-14 | 2008-05-22 | Genentech, Inc. | Modulators of neuronal regeneration |
| WO2009009743A2 (en) * | 2007-07-12 | 2009-01-15 | Institute For Advance Study | Sequence optimization for expression of a foreign gene |
| CN101971034A (zh) * | 2007-12-11 | 2011-02-09 | 健泰科生物技术公司 | 神经元再生的调控剂 |
| US8992918B2 (en) | 2008-03-13 | 2015-03-31 | Yale University | Reactivation of axon growth and recovery in chronic spinal cord injury |
| CL2009001155A1 (es) * | 2008-05-13 | 2010-06-04 | Genentech Inc | Anticuerpo anti-pirb/lilrb aislado; polinucleotido que lo codifica; vector; celula huesped; metodo de obtencion; composicion farmaceutica que lo comprende; kit; y su uso para tratar enfermedades neurodegenerativas. |
| DK2982695T3 (da) | 2008-07-09 | 2019-05-13 | Biogen Ma Inc | Sammensætninger, der omfatter antistoffer mod lingo eller fragmenter deraf |
| EP2392208B1 (en) * | 2010-06-07 | 2016-05-04 | Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) | Fusion proteins comprising a DNA-binding domain of a Tal effector protein and a non-specific cleavage domain of a restriction nuclease and their use |
| US9120111B2 (en) | 2012-02-24 | 2015-09-01 | Rain Bird Corporation | Arc adjustable rotary sprinkler having full-circle operation and automatic matched precipitation |
| NZ702178A (en) | 2012-05-14 | 2017-01-27 | Biogen Ma Inc | Lingo-2 antagonists for treatment of conditions involving motor neurons |
| US9156043B2 (en) | 2012-07-13 | 2015-10-13 | Rain Bird Corporation | Arc adjustable rotary sprinkler with automatic matched precipitation |
| WO2016112270A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
| US12343748B2 (en) | 2021-03-16 | 2025-07-01 | Rain Bird Corporation | Multi-mode rotor sprinkler apparatus and method |
| US12434252B2 (en) | 2022-04-20 | 2025-10-07 | Rain Bird Corporation | Full-circle and part-circle rotor sprinkler |
| US12440855B2 (en) | 2022-10-27 | 2025-10-14 | Rain Bird Corporation | Multi-mode rotor sprinkler apparatus and method |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5250414A (en) | 1988-11-04 | 1993-10-05 | Erziehungsdirektion Of The Canton Zurich | Diagnostic methods using neurite growth regulatory factors |
| AU652537B2 (en) | 1988-11-04 | 1994-09-01 | Erziehungsdirektion Of The Canton Zurich | Neurite growth regulatory factors |
| CA1341050C (en) | 1988-11-04 | 2000-07-11 | Martin E. Schwab | Neurite growth regulatory factors |
| CA2117889A1 (en) | 1993-02-11 | 1994-08-18 | Martin E. Schwab | A combination of neurotrophin and antibody directed toward myelin-associated neurite growth inhibitory protein promotes central nervous system regeneration |
| WO2000073452A2 (en) | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US5858708A (en) | 1996-08-12 | 1999-01-12 | Bandman; Olga | Polynucleotides encoding two novel human neuroendocrine-specific proteins |
| WO1999007891A1 (en) * | 1997-08-05 | 1999-02-18 | Human Genome Sciences, Inc. | 90 human secreted proteins |
| WO2000070050A1 (en) | 1999-05-14 | 2000-11-23 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| EP1490386B1 (en) | 1998-03-10 | 2008-08-13 | Genentech, Inc. | Novel polypeptide and nucleic acids encoding the same |
| JP2002518010A (ja) * | 1998-06-16 | 2002-06-25 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ９４個のヒト分泌タンパク質 |
| EP2264174A3 (en) | 1998-07-22 | 2012-03-07 | SmithKline Beecham Limited | Protein similar to neuroendocrine-specific protein, and encoding CDNA |
| KR100728405B1 (ko) * | 1998-11-06 | 2007-06-13 | 더 유니버시티 오브 취리히 | Ｎｏｇｏ 유전자의 뉴클레오티드와 단백질 서열 및 이들에기초한 방법 |
| EP1135485B1 (en) | 1998-12-01 | 2010-02-17 | Genentech, Inc. | Promotion or inhibition of angiogenesis and cardiovascularization |
| ES2327785T3 (es) | 1998-12-22 | 2009-11-03 | Genentech, Inc. | Procedimientos y compuestos para inhibir el crecimiento de celulas neoplasticas. |
| CA2362427A1 (en) | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| KR20030002292A (ko) | 1999-03-08 | 2003-01-08 | 제넨테크, 인크. | 분비 및 막횡단 폴리펩티드 및 이를 코딩하는 핵산 |
| EP1165784A2 (en) | 1999-03-31 | 2002-01-02 | Curagen Corporation | Nucleic acids including open reading frames encoding polypeptides; "orfx" |
| AU6394400A (en) | 1999-07-30 | 2001-02-19 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
| AU2575901A (en) * | 1999-12-08 | 2001-06-18 | Millennium Pharmaceuticals, Inc. | Novel leucine rich repeat-containing molecules and uses therefor |
| ES2341842T3 (es) * | 2000-01-12 | 2010-06-29 | Yale University | Bloqueo del crecimiento axonal mediado por el receptor de nogo. |
| US7119165B2 (en) * | 2000-01-12 | 2006-10-10 | Yale University | Nogo receptor-mediated blockade of axonal growth |
| US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
| US6695956B2 (en) | 2000-04-18 | 2004-02-24 | Teijin Limited | Oxygen concentrating apparatus |
| ES2341608T3 (es) * | 2000-10-06 | 2010-06-23 | Yale University | Homologos del receptor de nogo. |
| WO2003018631A2 (en) | 2001-08-27 | 2003-03-06 | Novartis Ag | Nogo receptor homologues and their use |
| JP2005519584A (ja) * | 2001-10-22 | 2005-07-07 | ノバルティス アクチエンゲゼルシャフト | Ｎｏｇｏレセプターホモログおよびそれらの使用 |
| CA2495121A1 (en) * | 2002-08-10 | 2004-02-19 | Yale University | Nogo receptor antagonists |
-
2001
- 2001-10-06 ES ES01979595T patent/ES2341608T3/es not_active Expired - Lifetime
- 2001-10-06 NZ NZ525422A patent/NZ525422A/en unknown
- 2001-10-06 AT AT01979595T patent/ATE458815T1/de active
- 2001-10-06 JP JP2002532629A patent/JP4465148B2/ja not_active Expired - Fee Related
- 2001-10-06 CA CA002424834A patent/CA2424834A1/en not_active Abandoned
- 2001-10-06 WO PCT/US2001/031488 patent/WO2002029059A2/en not_active Ceased
- 2001-10-06 AU AU1153902A patent/AU1153902A/xx active Pending
- 2001-10-06 DK DK01979595.4T patent/DK1325130T3/da active
- 2001-10-06 DE DE60141409T patent/DE60141409D1/de not_active Expired - Lifetime
- 2001-10-06 AU AU2002211539A patent/AU2002211539B2/en not_active Ceased
- 2001-10-06 US US09/972,546 patent/US20030124704A1/en not_active Abandoned
- 2001-10-06 PT PT01979595T patent/PT1325130E/pt unknown
- 2001-10-06 EP EP01979595A patent/EP1325130B1/en not_active Expired - Lifetime
-
2003
- 2003-12-12 US US10/735,256 patent/US7173118B2/en not_active Expired - Lifetime
-
2006
- 2006-10-06 US US11/544,013 patent/US7456255B2/en not_active Expired - Lifetime
-
2008
- 2008-11-24 US US12/277,187 patent/US20090175850A1/en not_active Abandoned
-
2009
- 2009-02-02 JP JP2009022063A patent/JP2009100767A/ja not_active Withdrawn
-
2010
- 2010-11-23 US US12/952,747 patent/US20110129477A1/en not_active Abandoned
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