JP2004525624A5 - - Google Patents
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- JP2004525624A5 JP2004525624A5 JP2002559584A JP2002559584A JP2004525624A5 JP 2004525624 A5 JP2004525624 A5 JP 2004525624A5 JP 2002559584 A JP2002559584 A JP 2002559584A JP 2002559584 A JP2002559584 A JP 2002559584A JP 2004525624 A5 JP2004525624 A5 JP 2004525624A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- ability
- nucleotide sequence
- library
- expression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 210000004027 cell Anatomy 0.000 claims 30
- 239000002773 nucleotide Substances 0.000 claims 16
- 125000003729 nucleotide group Chemical group 0.000 claims 16
- 238000000034 method Methods 0.000 claims 8
- 241000222120 Candida <Saccharomycetales> Species 0.000 claims 7
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 5
- 239000013598 vector Substances 0.000 claims 5
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 125000006850 spacer group Chemical group 0.000 claims 4
- 241000235648 Pichia Species 0.000 claims 3
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 claims 3
- 108091028732 Concatemer Proteins 0.000 claims 2
- 241000235058 Komagataella pastoris Species 0.000 claims 2
- 241000081271 Phaffia rhodozyma Species 0.000 claims 2
- 241000235015 Yarrowia lipolytica Species 0.000 claims 2
- 210000004507 artificial chromosome Anatomy 0.000 claims 2
- 238000010367 cloning Methods 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 230000003204 osmotic effect Effects 0.000 claims 2
- 108091008146 restriction endonucleases Proteins 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 210000005253 yeast cell Anatomy 0.000 claims 2
- 241000222178 Candida tropicalis Species 0.000 claims 1
- 201000007336 Cryptococcosis Diseases 0.000 claims 1
- 241000235646 Cyberlindnera jadinii Species 0.000 claims 1
- 241001465321 Eremothecium Species 0.000 claims 1
- 241001149669 Hanseniaspora Species 0.000 claims 1
- 108091092195 Intron Proteins 0.000 claims 1
- 241000235649 Kluyveromyces Species 0.000 claims 1
- 235000014663 Kluyveromyces fragilis Nutrition 0.000 claims 1
- 241001138401 Kluyveromyces lactis Species 0.000 claims 1
- 241000235650 Kluyveromyces marxianus Species 0.000 claims 1
- 241001489207 Lipomyces lipofer Species 0.000 claims 1
- 241000235048 Meyerozyma guilliermondii Species 0.000 claims 1
- 241000320412 Ogataea angusta Species 0.000 claims 1
- 101150053185 P450 gene Proteins 0.000 claims 1
- 241000235652 Pachysolen Species 0.000 claims 1
- 241000223252 Rhodotorula Species 0.000 claims 1
- 241000223253 Rhodotorula glutinis Species 0.000 claims 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 claims 1
- 235000018368 Saccharomyces fragilis Nutrition 0.000 claims 1
- 241000235343 Saccharomycetales Species 0.000 claims 1
- 241000235003 Saccharomycopsis Species 0.000 claims 1
- 241000192263 Scheffersomyces shehatae Species 0.000 claims 1
- 241000235060 Scheffersomyces stipitis Species 0.000 claims 1
- 241000383403 Solen Species 0.000 claims 1
- 241000192348 [Candida] palmioleophila Species 0.000 claims 1
- 229940031154 kluyveromyces marxianus Drugs 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 239000002574 poison Substances 0.000 claims 1
- 231100000614 poison Toxicity 0.000 claims 1
- 230000000644 propagated effect Effects 0.000 claims 1
- 229960002181 saccharomyces boulardii Drugs 0.000 claims 1
- 241000894007 species Species 0.000 claims 1
- 230000003595 spectral effect Effects 0.000 claims 1
- 239000000758 substrate Substances 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200100128 | 2001-01-25 | ||
| DKPA200100679 | 2001-05-01 | ||
| US30086301P | 2001-06-27 | 2001-06-27 | |
| PCT/DK2002/000056 WO2002059297A2 (en) | 2001-01-25 | 2002-01-25 | A library of a collection of cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009233636A Division JP4965625B2 (ja) | 2001-01-25 | 2009-10-07 | 細胞コレクションのライブラリー |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004525624A JP2004525624A (ja) | 2004-08-26 |
| JP2004525624A5 true JP2004525624A5 (https=) | 2005-12-22 |
Family
ID=43646216
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002559584A Withdrawn JP2004525624A (ja) | 2001-01-25 | 2002-01-25 | 細胞コレクションのライブラリー |
| JP2009233636A Expired - Fee Related JP4965625B2 (ja) | 2001-01-25 | 2009-10-07 | 細胞コレクションのライブラリー |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009233636A Expired - Fee Related JP4965625B2 (ja) | 2001-01-25 | 2009-10-07 | 細胞コレクションのライブラリー |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7838287B2 (https=) |
| EP (1) | EP1356037B1 (https=) |
| JP (2) | JP2004525624A (https=) |
| AT (1) | ATE501251T1 (https=) |
| AU (1) | AU2002227883A1 (https=) |
| CA (1) | CA2474172C (https=) |
| DE (1) | DE60239386D1 (https=) |
| DK (1) | DK1356037T3 (https=) |
| WO (1) | WO2002059297A2 (https=) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE60239386D1 (de) | 2001-01-25 | 2011-04-21 | Evolva Ltd | Zellbibliothek |
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| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| AU2003247270A1 (en) * | 2002-08-01 | 2004-03-03 | Evolva Ltd | Methods of mixing large numbers of heterologous genes |
| ES2408582T3 (es) | 2003-05-30 | 2013-06-21 | Merus B.V. | Biblioteca de Fab para la preparación de una mezcla de anticuerpos |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| DK1737971T3 (da) * | 2004-01-20 | 2017-11-13 | Merus Nv | Blandinger af bindingsproteiner |
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| KR101153866B1 (ko) | 2009-05-21 | 2012-06-27 | 대한민국 | 형질전환용 운반체, 이의 제조방법, 이를 이용한 형질전환방법 및 형질전환체 |
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| CA3128532A1 (en) | 2011-08-08 | 2013-02-14 | Evolva Sa | Recombinant production of steviol glycosides |
| SI2838917T1 (sl) | 2012-04-20 | 2019-11-29 | Merus Nv | Postopki in sredstva za produkcijo heterodimernih IG-podobnih molekul |
| WO2013191950A2 (en) | 2012-06-22 | 2013-12-27 | Monsanto Technology Llc | Unique modular vector design |
| CN104684923B (zh) | 2012-07-13 | 2018-09-28 | 株式会社新日本科学 | 手性核酸佐剂 |
| JP6453212B2 (ja) | 2012-07-13 | 2019-01-16 | ウェイブ ライフ サイエンシズ リミテッドＷａｖｅ Ｌｉｆｅ Ｓｃｉｅｎｃｅｓ Ｌｔｄ． | キラル制御 |
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| MY199452A (en) | 2013-02-06 | 2023-10-30 | Evolva Sa | Methods for improved production of rebaudioside d and rebaudioside m |
| BR112015019160A2 (pt) | 2013-02-11 | 2017-08-22 | Dalgaard Mikkelsen Michael | Produção de glicosídeos de esteviol em hospedeiros recombinantes |
| EP3046585B1 (en) | 2013-09-17 | 2021-08-25 | Bolt Threads, Inc. | Methods and compositions for synthesizing improved silk fibers |
| US9580758B2 (en) | 2013-11-12 | 2017-02-28 | Luc Montagnier | System and method for the detection and treatment of infection by a microbial agent associated with HIV infection |
| JPWO2015108046A1 (ja) | 2014-01-15 | 2017-03-23 | 株式会社新日本科学 | 抗アレルギー作用を有するキラル核酸アジュバンド及び抗アレルギー剤 |
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| CA2957331A1 (en) | 2014-08-11 | 2016-02-18 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| CA2960693A1 (en) | 2014-09-09 | 2016-03-17 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| EP3250686A1 (en) | 2015-01-30 | 2017-12-06 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| WO2016146711A1 (en) | 2015-03-16 | 2016-09-22 | Dsm Ip Assets B.V. | Udp-glycosyltransferases |
| MX2018001620A (es) | 2015-08-07 | 2018-06-11 | Evolva Sa | Produccion de glucosidos de esteviol en hospedadores recombinantes. |
| US10982249B2 (en) | 2016-04-13 | 2021-04-20 | Evolva Sa | Production of steviol glycosides in recombinant hosts |
| EP3458599A1 (en) | 2016-05-16 | 2019-03-27 | Evolva SA | Production of steviol glycosides in recombinant hosts |
| EP3512871A4 (en) | 2016-09-14 | 2020-07-29 | Bolt Threads, Inc. | LONG UNIFORM RECOMBINANT PROTEIN FIBERS |
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| JP7212982B1 (ja) | 2022-10-05 | 2023-01-26 | 株式会社Logomix | 細胞ライブラリおよびその製造方法 |
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-
2002
- 2002-01-25 DE DE60239386T patent/DE60239386D1/de not_active Expired - Lifetime
- 2002-01-25 AT AT02709979T patent/ATE501251T1/de not_active IP Right Cessation
- 2002-01-25 AU AU2002227883A patent/AU2002227883A1/en not_active Abandoned
- 2002-01-25 EP EP02709979A patent/EP1356037B1/en not_active Expired - Lifetime
- 2002-01-25 JP JP2002559584A patent/JP2004525624A/ja not_active Withdrawn
- 2002-01-25 US US10/466,960 patent/US7838287B2/en not_active Expired - Fee Related
- 2002-01-25 DK DK02709979.5T patent/DK1356037T3/da active
- 2002-01-25 CA CA2474172A patent/CA2474172C/en not_active Expired - Fee Related
- 2002-01-25 WO PCT/DK2002/000056 patent/WO2002059297A2/en not_active Ceased
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2009
- 2009-10-07 JP JP2009233636A patent/JP4965625B2/ja not_active Expired - Fee Related
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2010
- 2010-10-12 US US12/902,587 patent/US20120094870A1/en not_active Abandoned
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