JP2004523561A5 - - Google Patents
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- JP2004523561A5 JP2004523561A5 JP2002567927A JP2002567927A JP2004523561A5 JP 2004523561 A5 JP2004523561 A5 JP 2004523561A5 JP 2002567927 A JP2002567927 A JP 2002567927A JP 2002567927 A JP2002567927 A JP 2002567927A JP 2004523561 A5 JP2004523561 A5 JP 2004523561A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutically acceptable
- substituted
- compound
- acceptable salt
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27194101P | 2001-02-27 | 2001-02-27 | |
| PCT/US2002/005868 WO2002068414A2 (en) | 2001-02-27 | 2002-02-26 | Analogs of thalidomide as potential angiogenesis inhibitors |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009143087A Division JP2009263376A (ja) | 2001-02-27 | 2009-06-16 | 潜在的な血管形成阻害剤としてのサリドマイド類似体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004523561A JP2004523561A (ja) | 2004-08-05 |
| JP2004523561A5 true JP2004523561A5 (enExample) | 2005-12-22 |
| JP4361273B2 JP4361273B2 (ja) | 2009-11-11 |
Family
ID=23037728
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002567927A Expired - Fee Related JP4361273B2 (ja) | 2001-02-27 | 2002-02-26 | 潜在的な血管形成阻害剤としてのサリドマイド類似体 |
| JP2009143087A Pending JP2009263376A (ja) | 2001-02-27 | 2009-06-16 | 潜在的な血管形成阻害剤としてのサリドマイド類似体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009143087A Pending JP2009263376A (ja) | 2001-02-27 | 2009-06-16 | 潜在的な血管形成阻害剤としてのサリドマイド類似体 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7320991B2 (enExample) |
| EP (1) | EP1389203B8 (enExample) |
| JP (2) | JP4361273B2 (enExample) |
| AT (1) | ATE450529T1 (enExample) |
| AU (1) | AU2002306596B2 (enExample) |
| CA (1) | CA2439410C (enExample) |
| DE (1) | DE60234585D1 (enExample) |
| ES (1) | ES2338534T3 (enExample) |
| WO (1) | WO2002068414A2 (enExample) |
Families Citing this family (83)
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| US6458810B1 (en) | 2000-11-14 | 2002-10-01 | George Muller | Pharmaceutically active isoindoline derivatives |
| NZ526683A (en) * | 2000-11-30 | 2008-03-28 | Childrens Medical Center | Synthesis of 4-amino-thalidomide and its enantiomers that are suitable for inhibiting angiogenesis |
| EP1389203B8 (en) | 2001-02-27 | 2010-03-10 | The Governement of the United States of America, represented by The Secretary Department of Health and Human services | Analogs of thalidomide as angiogenesis inhibitors |
| USRE48890E1 (en) | 2002-05-17 | 2022-01-11 | Celgene Corporation | Methods for treating multiple myeloma with 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione after stem cell transplantation |
| US20100129363A1 (en) * | 2002-05-17 | 2010-05-27 | Zeldis Jerome B | Methods and compositions using pde4 inhibitors for the treatment and management of cancers |
| WO2003097040A1 (en) * | 2002-05-17 | 2003-11-27 | Celgene Corporation | Methods and compositions using selective cytokine inhibitory drugs for treatment and management of cancers and other diseases |
| US7323479B2 (en) * | 2002-05-17 | 2008-01-29 | Celgene Corporation | Methods for treatment and management of brain cancer using 1-oxo-2-(2,6-dioxopiperidin-3-yl)-4-methylisoindoline |
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| US7842691B2 (en) * | 2002-10-15 | 2010-11-30 | Celgene Corporation | Method for the treatment of myelodysplastic syndromes using cyclopropanecarboxylic acid {2-[1-(3-ethoxy-4-methoxy-phenyl)-2-methanesulfonyl-ethyl]-3-OXO-2,3-dihydro-1 H-isoindol-4-yl}-amide |
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| US11116782B2 (en) | 2002-10-15 | 2021-09-14 | Celgene Corporation | Methods of treating myelodysplastic syndromes with a combination therapy using lenalidomide and azacitidine |
| US20050203142A1 (en) * | 2002-10-24 | 2005-09-15 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment, modification and management of pain |
| US20040091455A1 (en) * | 2002-10-31 | 2004-05-13 | Zeldis Jerome B. | Methods of using and compositions comprising immunomodulatory compounds for treatment and management of macular degeneration |
| KR20090048520A (ko) | 2002-11-06 | 2009-05-13 | 셀진 코포레이션 | 암 및 다른 질환의 치료 및 관리를 위한 선택적 시토킨 억제 약물의 사용 방법 및 그 조성물 |
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| CN1188389C (zh) | 1998-05-15 | 2005-02-09 | 阿斯特拉曾尼卡有限公司 | 用于治疗由细胞因子引起的疾病的苯甲酰胺衍生物 |
| DE19843793C2 (de) * | 1998-09-24 | 2000-08-03 | Gruenenthal Gmbh | Substituierte Benzamide |
| US20030013739A1 (en) * | 1998-12-23 | 2003-01-16 | Pharmacia Corporation | Methods of using a combination of cyclooxygenase-2 selective inhibitors and thalidomide for the treatment of neoplasia |
| DK1040838T3 (da) | 1999-03-31 | 2003-05-26 | Gruenenthal Gmbh | Stabil vandig opløsning af 3-(1-oxo-1,3-dihydroisoindol-2-yl )piperidin-2,6-dion |
| US6310360B1 (en) * | 1999-07-21 | 2001-10-30 | The Trustees Of Princeton University | Intersystem crossing agents for efficient utilization of excitons in organic light emitting devices |
| AU4515001A (en) * | 1999-12-02 | 2001-06-18 | Regents Of The University Of Michigan, The | Compositions and methods for locally treating inflammatory diseases |
| AU2001249755A1 (en) * | 2000-03-31 | 2001-10-15 | Celgene Corporation | Inhibition of cyclooxygenase-2 activity |
| US6458810B1 (en) * | 2000-11-14 | 2002-10-01 | George Muller | Pharmaceutically active isoindoline derivatives |
| NZ526683A (en) | 2000-11-30 | 2008-03-28 | Childrens Medical Center | Synthesis of 4-amino-thalidomide and its enantiomers that are suitable for inhibiting angiogenesis |
| EP1389203B8 (en) | 2001-02-27 | 2010-03-10 | The Governement of the United States of America, represented by The Secretary Department of Health and Human services | Analogs of thalidomide as angiogenesis inhibitors |
| NZ531294A (en) | 2001-08-06 | 2005-11-25 | Childrens Medical Center | Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs |
| EP1336602A1 (en) | 2002-02-13 | 2003-08-20 | Giovanni Scaramuzzino | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases |
| EP2272513A1 (en) | 2002-05-17 | 2011-01-12 | Celgene Corporation | Pharmaceutical compositions for treating cancer |
| CN100488959C (zh) | 2003-03-27 | 2009-05-20 | 天津和美生物技术有限公司 | 水溶性的酞胺哌啶酮衍生物 |
| EP1546146A1 (en) | 2003-06-03 | 2005-06-29 | Teva Pharmaceutical Industries Limited | POLYMORPHIC FORMS OF ZIPRASIDONE HCl AND PROCESSES FOR THEIR PREPARATION |
| WO2005016326A2 (en) | 2003-07-11 | 2005-02-24 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Analogs of thalidomide as potential angiogenesis inhibitors |
-
2002
- 2002-02-26 EP EP02780964A patent/EP1389203B8/en not_active Expired - Lifetime
- 2002-02-26 ES ES02780964T patent/ES2338534T3/es not_active Expired - Lifetime
- 2002-02-26 AU AU2002306596A patent/AU2002306596B2/en not_active Ceased
- 2002-02-26 WO PCT/US2002/005868 patent/WO2002068414A2/en not_active Ceased
- 2002-02-26 AT AT02780964T patent/ATE450529T1/de not_active IP Right Cessation
- 2002-02-26 CA CA2439410A patent/CA2439410C/en not_active Expired - Fee Related
- 2002-02-26 DE DE60234585T patent/DE60234585D1/de not_active Expired - Lifetime
- 2002-02-26 US US10/469,359 patent/US7320991B2/en not_active Expired - Fee Related
- 2002-02-26 JP JP2002567927A patent/JP4361273B2/ja not_active Expired - Fee Related
-
2007
- 2007-07-19 US US11/880,404 patent/US8716315B2/en not_active Expired - Fee Related
-
2009
- 2009-06-16 JP JP2009143087A patent/JP2009263376A/ja active Pending
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