JP2004522780A - トルセミド・モディフィケーションiiを含む安定な医薬品製剤 - Google Patents

トルセミド・モディフィケーションiiを含む安定な医薬品製剤 Download PDF

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JP2004522780A
JP2004522780A JP2002567302A JP2002567302A JP2004522780A JP 2004522780 A JP2004522780 A JP 2004522780A JP 2002567302 A JP2002567302 A JP 2002567302A JP 2002567302 A JP2002567302 A JP 2002567302A JP 2004522780 A JP2004522780 A JP 2004522780A
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Japan
Prior art keywords
torsemide modification
stable pharmaceutical
pharmaceutical formulation
modification
high purity
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JP2002567302A
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Japanese (ja)
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JP2004522780A5 (enExample
Inventor
レイボビチ,ミヌツァ
テネンガウザー,ルース
コペル,ミラ
アロンヒメ,ジュディス
コルドバ,マルコ
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テバ ファーマシューティカル インダストリーズ リミティド
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Application filed by テバ ファーマシューティカル インダストリーズ リミティド filed Critical テバ ファーマシューティカル インダストリーズ リミティド
Publication of JP2004522780A publication Critical patent/JP2004522780A/ja
Publication of JP2004522780A5 publication Critical patent/JP2004522780A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002567302A 2000-02-17 2001-02-21 トルセミド・モディフィケーションiiを含む安定な医薬品製剤 Withdrawn JP2004522780A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18328800P 2000-02-17 2000-02-17
PCT/US2001/005577 WO2002067935A1 (en) 2000-02-17 2001-02-21 A stable pharmaceutical formulation comprising torsemide modification ii
US09/789,424 US6482417B2 (en) 2000-02-17 2001-02-21 Stable pharmaceutical formulation comprising torsemide modification II

Publications (2)

Publication Number Publication Date
JP2004522780A true JP2004522780A (ja) 2004-07-29
JP2004522780A5 JP2004522780A5 (enExample) 2006-01-05

Family

ID=27359046

Family Applications (1)

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JP2002567302A Withdrawn JP2004522780A (ja) 2000-02-17 2001-02-21 トルセミド・モディフィケーションiiを含む安定な医薬品製剤

Country Status (20)

Country Link
US (1) US6482417B2 (enExample)
EP (1) EP1292303B1 (enExample)
JP (1) JP2004522780A (enExample)
CN (1) CN1505512A (enExample)
AT (1) ATE266404T1 (enExample)
CA (1) CA2410802A1 (enExample)
DE (2) DE1292303T1 (enExample)
DK (1) DK1292303T3 (enExample)
ES (1) ES2193007T3 (enExample)
HR (1) HRP20030762A2 (enExample)
HU (1) HUP0600143A2 (enExample)
IL (1) IL157539A0 (enExample)
IS (1) IS6919A (enExample)
MX (1) MXPA03007908A (enExample)
NO (1) NO20033699L (enExample)
PT (1) PT1292303E (enExample)
SI (1) SI1292303T1 (enExample)
SK (1) SK11632003A3 (enExample)
TR (1) TR200401462T4 (enExample)
WO (1) WO2002067935A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024525954A (ja) * 2021-07-20 2024-07-12 ミネラリス・セラピューティクス・インコーポレイテッド 二置換1,2,4-トリアジン化合物の塩を含む可溶性薬学的組成物

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10013289A1 (de) * 2000-03-17 2001-09-20 Knoll Ag Torasemid enthaltende pharmazeutische Zubereitungen
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
ITMI20020639A1 (it) * 2002-03-27 2003-09-29 Cosma S P A Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
WO2005044187A2 (en) * 2003-10-28 2005-05-19 Glaxo Group Limited Inhalable pharmaceutical formulations employing lactose anhydrate and methods of administering the same
ES2244324B1 (es) * 2004-03-25 2006-11-16 Ferrer Internacional, S.A. Composiciones diureticas de liberacion prolongada.
CN100421662C (zh) * 2005-11-08 2008-10-01 周卓和 托拉塞米分散片及其制备方法和应用
CN100372534C (zh) * 2006-04-20 2008-03-05 南京海辰药业有限公司 托拉塞米冻干制剂及制备方法
US20080213362A1 (en) * 2007-02-02 2008-09-04 Lawrence Solomon Compositions and methods using torsemide
CN106038500A (zh) * 2016-05-26 2016-10-26 南京正科医药股份有限公司 一种托拉塞米片
GR1010905B (el) * 2024-04-15 2025-03-10 Win Medica Φαρμακευτικη Ανωνυμη Εταιρεια, Δισκιο που περιεχει τορασεμιδη

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1477664A (en) 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
DE3529529A1 (de) 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
DE69624559T2 (de) * 1995-02-28 2003-07-10 Aventis Pharmaceuticals Inc., Bridgewater Arzneizubereitungen für piperidinalkanolderivate
US5914336A (en) * 1998-06-02 1999-06-22 Boehringer Mannheim Gmbh Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
KR20020025217A (ko) * 1999-08-11 2002-04-03 추후보정 토르세미드 동질이상

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024525954A (ja) * 2021-07-20 2024-07-12 ミネラリス・セラピューティクス・インコーポレイテッド 二置換1,2,4-トリアジン化合物の塩を含む可溶性薬学的組成物

Also Published As

Publication number Publication date
MXPA03007908A (es) 2004-12-06
SK11632003A3 (sk) 2004-04-06
DE1292303T1 (de) 2003-09-18
NO20033699D0 (no) 2003-08-20
PT1292303E (pt) 2004-09-30
IS6919A (is) 2003-08-20
IL157539A0 (en) 2004-03-28
ES2193007T1 (es) 2003-11-01
CA2410802A1 (en) 2002-09-06
HRP20030762A2 (en) 2005-08-31
WO2002067935A1 (en) 2002-09-06
SI1292303T1 (en) 2004-10-31
HUP0600143A2 (en) 2006-10-28
ATE266404T1 (de) 2004-05-15
US20020035135A1 (en) 2002-03-21
EP1292303A1 (en) 2003-03-19
DE60103276T2 (de) 2005-06-23
NO20033699L (no) 2003-10-10
EP1292303A4 (en) 2003-07-09
DK1292303T3 (da) 2004-09-06
DE60103276D1 (de) 2004-06-17
US6482417B2 (en) 2002-11-19
CN1505512A (zh) 2004-06-16
ES2193007T3 (es) 2004-11-01
EP1292303B1 (en) 2004-05-12
TR200401462T4 (tr) 2004-08-23

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