DE60103276D1 - Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält - Google Patents

Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält

Info

Publication number
DE60103276D1
DE60103276D1 DE60103276T DE60103276T DE60103276D1 DE 60103276 D1 DE60103276 D1 DE 60103276D1 DE 60103276 T DE60103276 T DE 60103276T DE 60103276 T DE60103276 T DE 60103276T DE 60103276 D1 DE60103276 D1 DE 60103276D1
Authority
DE
Germany
Prior art keywords
modification
stable pharmaceutical
torsemid
pharmaceutical formulation
high purity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60103276T
Other languages
English (en)
Other versions
DE60103276T2 (de
Inventor
Minutza Leibovici
Ruth Tenengauzer
Mira Kopel
Judith Aronhime
Marco Kordova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teva Pharmaceutical Industries Ltd
Original Assignee
Teva Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27359046&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60103276(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd filed Critical Teva Pharmaceutical Industries Ltd
Publication of DE60103276D1 publication Critical patent/DE60103276D1/de
Application granted granted Critical
Publication of DE60103276T2 publication Critical patent/DE60103276T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE60103276T 2000-02-17 2001-02-21 Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält Expired - Fee Related DE60103276T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US18328800P 2000-02-17 2000-02-17
US09/789,424 US6482417B2 (en) 2000-02-17 2001-02-21 Stable pharmaceutical formulation comprising torsemide modification II
PCT/US2001/005577 WO2002067935A1 (en) 2000-02-17 2001-02-21 A stable pharmaceutical formulation comprising torsemide modification ii

Publications (2)

Publication Number Publication Date
DE60103276D1 true DE60103276D1 (de) 2004-06-17
DE60103276T2 DE60103276T2 (de) 2005-06-23

Family

ID=27359046

Family Applications (2)

Application Number Title Priority Date Filing Date
DE1292303T Pending DE1292303T1 (de) 2000-02-17 2001-02-21 Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält
DE60103276T Expired - Fee Related DE60103276T2 (de) 2000-02-17 2001-02-21 Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE1292303T Pending DE1292303T1 (de) 2000-02-17 2001-02-21 Eine stabile pharmazeutische formulierung die torsemid modifikation ii enthält

Country Status (20)

Country Link
US (1) US6482417B2 (de)
EP (1) EP1292303B1 (de)
JP (1) JP2004522780A (de)
CN (1) CN1505512A (de)
AT (1) ATE266404T1 (de)
CA (1) CA2410802A1 (de)
DE (2) DE1292303T1 (de)
DK (1) DK1292303T3 (de)
ES (1) ES2193007T3 (de)
HR (1) HRP20030762A2 (de)
HU (1) HUP0600143A2 (de)
IL (1) IL157539A0 (de)
IS (1) IS6919A (de)
MX (1) MXPA03007908A (de)
NO (1) NO20033699L (de)
PT (1) PT1292303E (de)
SI (1) SI1292303T1 (de)
SK (1) SK11632003A3 (de)
TR (1) TR200401462T4 (de)
WO (1) WO2002067935A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10013289A1 (de) * 2000-03-17 2001-09-20 Knoll Ag Torasemid enthaltende pharmazeutische Zubereitungen
US20030022921A1 (en) * 2001-02-21 2003-01-30 Minutza Leibovici Stable pharmaceutical formulation comprising torsemide modification II
ITMI20020639A1 (it) 2002-03-27 2003-09-29 Cosma S P A Composizioni farmaceutiche comprendenti come principio attivo 1-isopropil-3°(4-m-toluidino-3-pridil)sulfonil!-urea
JP2007509941A (ja) * 2003-10-28 2007-04-19 グラクソ　グループ　リミテッド ラクトース無水物を用いる吸入医薬製剤およびその投与方法
ES2244324B1 (es) * 2004-03-25 2006-11-16 Ferrer Internacional, S.A. Composiciones diureticas de liberacion prolongada.
CN100421662C (zh) * 2005-11-08 2008-10-01 周卓和 托拉塞米分散片及其制备方法和应用
CN100372534C (zh) * 2006-04-20 2008-03-05 南京海辰药业有限公司 托拉塞米冻干制剂及制备方法
US20080213362A1 (en) * 2007-02-02 2008-09-04 Lawrence Solomon Compositions and methods using torsemide
CN106038500A (zh) * 2016-05-26 2016-10-26 南京正科医药股份有限公司 一种托拉塞米片

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1477664A (en) 1974-04-17 1977-06-22 Christiaens Sa A Pyridine derivatives
DE3529529A1 (de) * 1985-08-17 1987-02-19 Boehringer Mannheim Gmbh Verfahren zur herstellung einer stabilen modifikation von torasemid
EP0812195B1 (de) * 1995-02-28 2002-10-30 Aventis Pharmaceuticals Inc. Arzneizubereitungen für piperidinalkanolderivate
US5914336A (en) * 1998-06-02 1999-06-22 Boehringer Mannheim Gmbh Method of controlling the serum solubility of orally administered torasemide and composition relating thereto
CZ2002404A3 (cs) * 1999-08-11 2002-06-12 Teva Pharmaceutical Industries Ltd. Polymorfní formy torsemidu

Also Published As

Publication number Publication date
ES2193007T3 (es) 2004-11-01
ES2193007T1 (es) 2003-11-01
EP1292303A4 (de) 2003-07-09
IS6919A (is) 2003-08-20
IL157539A0 (en) 2004-03-28
CA2410802A1 (en) 2002-09-06
DE1292303T1 (de) 2003-09-18
TR200401462T4 (tr) 2004-08-23
EP1292303A1 (de) 2003-03-19
WO2002067935A1 (en) 2002-09-06
NO20033699L (no) 2003-10-10
ATE266404T1 (de) 2004-05-15
EP1292303B1 (de) 2004-05-12
US6482417B2 (en) 2002-11-19
JP2004522780A (ja) 2004-07-29
US20020035135A1 (en) 2002-03-21
HUP0600143A2 (en) 2006-10-28
SI1292303T1 (en) 2004-10-31
NO20033699D0 (no) 2003-08-20
DK1292303T3 (da) 2004-09-06
MXPA03007908A (es) 2004-12-06
CN1505512A (zh) 2004-06-16
PT1292303E (pt) 2004-09-30
SK11632003A3 (sk) 2004-04-06
DE60103276T2 (de) 2005-06-23
HRP20030762A2 (en) 2005-08-31

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8339 Ceased/non-payment of the annual fee