NO20034863D0 - Deuterert 3-piperidinopropiofenon og medikamenter inneholdende disse - Google Patents

Deuterert 3-piperidinopropiofenon og medikamenter inneholdende disse

Info

Publication number
NO20034863D0
NO20034863D0 NO20034863A NO20034863A NO20034863D0 NO 20034863 D0 NO20034863 D0 NO 20034863D0 NO 20034863 A NO20034863 A NO 20034863A NO 20034863 A NO20034863 A NO 20034863A NO 20034863 D0 NO20034863 D0 NO 20034863D0
Authority
NO
Norway
Prior art keywords
deuterated
piperidinopropiophenones
illnesses
muscular
treatment
Prior art date
Application number
NO20034863A
Other languages
English (en)
Other versions
NO20034863L (no
Inventor
Rudolf-Giesbert Alken
Thomas Stabingis
Original Assignee
Turicum Drug Dev Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Turicum Drug Dev Ag filed Critical Turicum Drug Dev Ag
Publication of NO20034863D0 publication Critical patent/NO20034863D0/no
Publication of NO20034863L publication Critical patent/NO20034863L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/104Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/108Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20034863A 2001-05-02 2003-10-31 Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser NO20034863L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10123129A DE10123129A1 (de) 2001-05-02 2001-05-02 Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel
PCT/DE2002/001607 WO2002088100A2 (de) 2001-05-02 2002-04-29 Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
NO20034863D0 true NO20034863D0 (no) 2003-10-31
NO20034863L NO20034863L (no) 2003-12-30

Family

ID=7684543

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034863A NO20034863L (no) 2001-05-02 2003-10-31 Deutererte 3-piperidinopropiofenon så vel som legemidler som inneholder disse forbindelser

Country Status (22)

Country Link
US (1) US7307091B2 (no)
EP (1) EP1383752B1 (no)
JP (1) JP4373097B2 (no)
KR (1) KR100894846B1 (no)
CN (2) CN1293064C (no)
AT (1) ATE298324T1 (no)
AU (1) AU2002257562B2 (no)
CA (1) CA2446890C (no)
CZ (1) CZ20033060A3 (no)
DE (2) DE10123129A1 (no)
DK (1) DK1383752T3 (no)
ES (1) ES2244768T3 (no)
HU (1) HUP0400077A2 (no)
IL (1) IL158668A0 (no)
IS (1) IS7006A (no)
NO (1) NO20034863L (no)
NZ (1) NZ529586A (no)
PL (1) PL363313A1 (no)
PT (1) PT1383752E (no)
RU (1) RU2296755C2 (no)
SI (1) SI1383752T1 (no)
WO (1) WO2002088100A2 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10261807A1 (de) * 2002-12-19 2004-07-01 Turicum Drug Development Ag Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
HUP0300929A3 (en) * 2003-04-09 2005-06-28 Richter Gedeon Vegyeszet Analgetic and/or muscle relaxant pharmaceutical composition
DE102005014080B4 (de) * 2005-03-21 2007-11-22 Birds Pharma Gmbh Berolina Innovative Research & Development Services Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel
WO2007012651A1 (en) * 2005-07-26 2007-02-01 Nycomed Gmbh Isotopically substituted pantoprazole
AR054584A1 (es) * 2005-07-26 2007-06-27 Altana Pharma Ag Inhibidores de la bomba de protones isotopicamente sustituidos
US7601737B2 (en) * 2005-07-26 2009-10-13 Nycomed Gmbh Isotopically substituted proton pump inhibitors
US7598273B2 (en) * 2005-10-06 2009-10-06 Auspex Pharmaceuticals, Inc Inhibitors of the gastric H+, K+-ATPase with enhanced therapeutic properties
US8604031B2 (en) 2006-05-18 2013-12-10 Mannkind Corporation Intracellular kinase inhibitors
EP2049117A4 (en) * 2006-08-08 2010-08-25 Auspex Pharmaceuticals Inc PREPARATION AND USE OF SUBSTITUTED CHINAZOLIN COMPOUNDS WITH ALPHA-ADRENERGER BLOKING EFFECT
EA201390332A1 (ru) * 2010-09-03 2013-08-30 Ивакс Интернэшнл Гмбх Дейтерированные аналоги придопидина, применимые в качестве допаминергических стабилизаторов
KR102495941B1 (ko) 2013-12-03 2023-02-06 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
CA2944512C (en) * 2014-04-04 2018-04-24 Intra-Cellular Therapies, Inc. Heterocycle fused gamma-carbolines for treatment of central nervous system disorders
WO2017105881A1 (en) * 2015-12-15 2017-06-22 NeuForm Pharmaceuticals, Inc. Deuterated compounds for treating pain
CA3016353C (en) 2016-03-25 2021-04-27 Intra-Cellular Therapies, Inc. Deuterated fused heterocycle gamma-carbolines and compositions thereof useful in the treatment of nervous system disorders
JP7013454B2 (ja) 2016-10-12 2022-02-15 イントラ-セルラー・セラピーズ・インコーポレイテッド アモルファス固体分散体
CN106588817A (zh) * 2016-12-13 2017-04-26 湖南亚大制药有限公司 一种盐酸乙哌立松的合成方法
MX2019011329A (es) 2017-03-24 2019-12-02 Intra Celular Therapies Inc Composiciones novedosas y metodos.
EP3843739A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS
EP3843738A4 (en) 2018-08-31 2022-06-01 Intra-Cellular Therapies, Inc. NEW METHODS
CN110845443B (zh) * 2019-12-11 2023-09-05 嘉实(湖南)医药科技有限公司 一种制备高纯度盐酸托哌酮的方法
CN117003605B (zh) * 2023-08-07 2024-06-11 宁波萃英化学技术有限公司 一种氘代萘基蒽类化合物的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5527914B2 (no) * 1973-12-14 1980-07-24
US3995047A (en) * 1973-12-14 1976-11-30 Eisai Co., Ltd. Propiophenone derivatives in the treatment of pathological muscular conditions
HU33131A (no) * 1984-01-26 1984-10-29

Also Published As

Publication number Publication date
IS7006A (is) 2003-10-30
CA2446890A1 (en) 2002-11-07
PT1383752E (pt) 2005-11-30
WO2002088100A2 (de) 2002-11-07
RU2296755C2 (ru) 2007-04-10
CA2446890C (en) 2010-02-23
NZ529586A (en) 2005-07-29
US7307091B2 (en) 2007-12-11
KR20040015240A (ko) 2004-02-18
IL158668A0 (en) 2004-05-12
PL363313A1 (en) 2004-11-15
EP1383752B1 (de) 2005-06-22
RU2003133924A (ru) 2005-05-10
CN101002770A (zh) 2007-07-25
CZ20033060A3 (cs) 2004-09-15
JP4373097B2 (ja) 2009-11-25
DE50203456D1 (de) 2005-07-28
DK1383752T3 (da) 2005-10-17
JP2004527558A (ja) 2004-09-09
ATE298324T1 (de) 2005-07-15
NO20034863L (no) 2003-12-30
HUP0400077A2 (hu) 2004-04-28
AU2002257562B2 (en) 2007-01-11
SI1383752T1 (sl) 2005-12-31
WO2002088100A3 (de) 2003-05-30
ES2244768T3 (es) 2005-12-16
CN1293064C (zh) 2007-01-03
EP1383752A2 (de) 2004-01-28
CN1527823A (zh) 2004-09-08
US20040186136A1 (en) 2004-09-23
DE10123129A1 (de) 2002-11-14
KR100894846B1 (ko) 2009-04-24

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Legal Events

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FC2A Withdrawal, rejection or dismissal of laid open patent application