IL158668A0 - Deuterated 3-piperidinopropiophenone and medicaments containing said compounds - Google Patents
Deuterated 3-piperidinopropiophenone and medicaments containing said compoundsInfo
- Publication number
- IL158668A0 IL158668A0 IL15866802A IL15866802A IL158668A0 IL 158668 A0 IL158668 A0 IL 158668A0 IL 15866802 A IL15866802 A IL 15866802A IL 15866802 A IL15866802 A IL 15866802A IL 158668 A0 IL158668 A0 IL 158668A0
- Authority
- IL
- Israel
- Prior art keywords
- deuterated
- piperidinopropiophenones
- illnesses
- muscular
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/10—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
- C07D295/104—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/108—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B59/00—Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123129A DE10123129A1 (de) | 2001-05-02 | 2001-05-02 | Deuterierte 3-Piperidinopropiophenone sowie diese Verbindungen enthaltende Arzneimittel |
| PCT/DE2002/001607 WO2002088100A2 (de) | 2001-05-02 | 2002-04-29 | Deuterierte 3-piperidinopropiophenone sowie diese verbindungen enthaltende arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL158668A0 true IL158668A0 (en) | 2004-05-12 |
Family
ID=7684543
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL15866802A IL158668A0 (en) | 2001-05-02 | 2002-04-29 | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7307091B2 (xx) |
| EP (1) | EP1383752B1 (xx) |
| JP (1) | JP4373097B2 (xx) |
| KR (1) | KR100894846B1 (xx) |
| CN (2) | CN1293064C (xx) |
| AT (1) | ATE298324T1 (xx) |
| AU (1) | AU2002257562B2 (xx) |
| CA (1) | CA2446890C (xx) |
| CZ (1) | CZ20033060A3 (xx) |
| DE (2) | DE10123129A1 (xx) |
| DK (1) | DK1383752T3 (xx) |
| ES (1) | ES2244768T3 (xx) |
| HU (1) | HUP0400077A2 (xx) |
| IL (1) | IL158668A0 (xx) |
| IS (1) | IS7006A (xx) |
| NO (1) | NO20034863L (xx) |
| NZ (1) | NZ529586A (xx) |
| PL (1) | PL363313A1 (xx) |
| PT (1) | PT1383752E (xx) |
| RU (1) | RU2296755C2 (xx) |
| SI (1) | SI1383752T1 (xx) |
| WO (1) | WO2002088100A2 (xx) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10261807A1 (de) | 2002-12-19 | 2004-07-01 | Turicum Drug Development Ag | Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel |
| HUP0300929A3 (en) * | 2003-04-09 | 2005-06-28 | Richter Gedeon Vegyeszet | Analgetic and/or muscle relaxant pharmaceutical composition |
| DE102005014080B4 (de) * | 2005-03-21 | 2007-11-22 | Birds Pharma Gmbh Berolina Innovative Research & Development Services | Additionssalze des Tolperison, Verfahren zu deren Herstellung, Verwendung derselben und diese enthaltende Arzneimittel |
| EP1910293A1 (en) * | 2005-07-26 | 2008-04-16 | Nycomed GmbH | Isotopically substituted proton pump inhibitors |
| US7601737B2 (en) * | 2005-07-26 | 2009-10-13 | Nycomed Gmbh | Isotopically substituted proton pump inhibitors |
| EP1912947A1 (en) * | 2005-07-26 | 2008-04-23 | Nycomed GmbH | Isotopically substituted pantoprazole |
| CN101309917B (zh) * | 2005-10-06 | 2013-09-11 | 奥斯拜客斯制药有限公司 | 具有增强治疗性质的胃h+，k+-atp酶氘代抑制剂 |
| US8604031B2 (en) | 2006-05-18 | 2013-12-10 | Mannkind Corporation | Intracellular kinase inhibitors |
| WO2008021891A2 (en) * | 2006-08-08 | 2008-02-21 | Auspex Pharmaceuticals, Inc. | Preparation and utility of substituted quinazoline compounds with alpha-adrenergic blocking effects |
| EP2611759A1 (en) * | 2010-09-03 | 2013-07-10 | Ivax International Gmbh | Deuterated analogs of pridopidine useful as dopaminergic stabilizers |
| AU2014360452C1 (en) | 2013-12-03 | 2019-05-16 | Intra-Cellular Therapies, Inc. | Novel methods |
| BR112016023162B1 (pt) | 2014-04-04 | 2022-11-29 | Intra-Cellular Therapies, Inc | Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central |
| WO2017105881A1 (en) * | 2015-12-15 | 2017-06-22 | NeuForm Pharmaceuticals, Inc. | Deuterated compounds for treating pain |
| EP3888656A1 (en) | 2016-03-25 | 2021-10-06 | Intra-Cellular Therapies, Inc. | Deuterated heterocyclic gamma-carboline compounds and their use in the treatment or prophylaxis of a central nervous system disorder |
| CN110072518B (zh) | 2016-10-12 | 2021-10-26 | 细胞内治疗公司 | 无定形固体分散体 |
| CN106588817A (zh) * | 2016-12-13 | 2017-04-26 | 湖南亚大制药有限公司 | 一种盐酸乙哌立松的合成方法 |
| MX2019011329A (es) | 2017-03-24 | 2019-12-02 | Intra Celular Therapies Inc | Composiciones novedosas y metodos. |
| MX2021002321A (es) | 2018-08-31 | 2021-04-28 | Intra Cellular Therapies Inc | Nuevos metodos. |
| AU2019328528A1 (en) | 2018-08-31 | 2021-03-18 | Intra-Cellular Therapies, Inc. | Novel methods |
| KR20220029744A (ko) | 2019-07-07 | 2022-03-08 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규 방법 |
| CN110845443B (zh) * | 2019-12-11 | 2023-09-05 | 嘉实（湖南）医药科技有限公司 | 一种制备高纯度盐酸托哌酮的方法 |
| JP7506039B2 (ja) | 2020-03-25 | 2024-06-25 | カシオ計算機株式会社 | 売上データ処理装置、レシート発行方法及びプログラム |
| CN117003605B (zh) * | 2023-08-07 | 2024-06-11 | 宁波萃英化学技术有限公司 | 一种氘代萘基蒽类化合物的制备方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5527914B2 (xx) * | 1973-12-14 | 1980-07-24 | ||
| US3995047A (en) * | 1973-12-14 | 1976-11-30 | Eisai Co., Ltd. | Propiophenone derivatives in the treatment of pathological muscular conditions |
| HU33131A (xx) * | 1984-01-26 | 1984-10-29 |
-
2001
- 2001-05-02 DE DE10123129A patent/DE10123129A1/de not_active Withdrawn
-
2002
- 2002-04-29 WO PCT/DE2002/001607 patent/WO2002088100A2/de active IP Right Grant
- 2002-04-29 HU HU0400077A patent/HUP0400077A2/hu unknown
- 2002-04-29 IL IL15866802A patent/IL158668A0/xx unknown
- 2002-04-29 RU RU2003133924/04A patent/RU2296755C2/ru not_active IP Right Cessation
- 2002-04-29 SI SI200230177T patent/SI1383752T1/sl unknown
- 2002-04-29 PL PL02363313A patent/PL363313A1/xx unknown
- 2002-04-29 PT PT02727303T patent/PT1383752E/pt unknown
- 2002-04-29 NZ NZ529586A patent/NZ529586A/en unknown
- 2002-04-29 DK DK02727303T patent/DK1383752T3/da active
- 2002-04-29 CN CNB028106121A patent/CN1293064C/zh not_active Expired - Fee Related
- 2002-04-29 CA CA2446890A patent/CA2446890C/en not_active Expired - Fee Related
- 2002-04-29 CZ CZ20033060A patent/CZ20033060A3/cs unknown
- 2002-04-29 ES ES02727303T patent/ES2244768T3/es not_active Expired - Lifetime
- 2002-04-29 DE DE50203456T patent/DE50203456D1/de not_active Expired - Lifetime
- 2002-04-29 JP JP2002585402A patent/JP4373097B2/ja not_active Expired - Fee Related
- 2002-04-29 KR KR1020037014301A patent/KR100894846B1/ko not_active IP Right Cessation
- 2002-04-29 US US10/476,743 patent/US7307091B2/en not_active Expired - Lifetime
- 2002-04-29 AU AU2002257562A patent/AU2002257562B2/en not_active Ceased
- 2002-04-29 EP EP02727303A patent/EP1383752B1/de not_active Expired - Lifetime
- 2002-04-29 CN CNA2006101485698A patent/CN101002770A/zh active Pending
- 2002-04-29 AT AT02727303T patent/ATE298324T1/de not_active IP Right Cessation
-
2003
- 2003-10-30 IS IS7006A patent/IS7006A/is unknown
- 2003-10-31 NO NO20034863A patent/NO20034863L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU2002257562B2 (en) | 2007-01-11 |
| US7307091B2 (en) | 2007-12-11 |
| DE10123129A1 (de) | 2002-11-14 |
| IS7006A (is) | 2003-10-30 |
| EP1383752A2 (de) | 2004-01-28 |
| NZ529586A (en) | 2005-07-29 |
| PT1383752E (pt) | 2005-11-30 |
| WO2002088100A2 (de) | 2002-11-07 |
| PL363313A1 (en) | 2004-11-15 |
| RU2003133924A (ru) | 2005-05-10 |
| DK1383752T3 (da) | 2005-10-17 |
| CN1293064C (zh) | 2007-01-03 |
| EP1383752B1 (de) | 2005-06-22 |
| US20040186136A1 (en) | 2004-09-23 |
| CN101002770A (zh) | 2007-07-25 |
| RU2296755C2 (ru) | 2007-04-10 |
| NO20034863D0 (no) | 2003-10-31 |
| CZ20033060A3 (cs) | 2004-09-15 |
| DE50203456D1 (de) | 2005-07-28 |
| WO2002088100A3 (de) | 2003-05-30 |
| SI1383752T1 (sl) | 2005-12-31 |
| KR20040015240A (ko) | 2004-02-18 |
| JP4373097B2 (ja) | 2009-11-25 |
| KR100894846B1 (ko) | 2009-04-24 |
| JP2004527558A (ja) | 2004-09-09 |
| ES2244768T3 (es) | 2005-12-16 |
| ATE298324T1 (de) | 2005-07-15 |
| NO20034863L (no) | 2003-12-30 |
| CA2446890A1 (en) | 2002-11-07 |
| CN1527823A (zh) | 2004-09-08 |
| CA2446890C (en) | 2010-02-23 |
| HUP0400077A2 (hu) | 2004-04-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL158668A0 (en) | Deuterated 3-piperidinopropiophenone and medicaments containing said compounds | |
| AP1818A (en) | Urea-compounds active as vanilloid receptor antagonists for the treatment of pain | |
| EA200301165A1 (ru) | Лекарственное средство на основе оксикодона | |
| WO2005065069A3 (en) | Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease | |
| WO2004112711A3 (en) | Oral extended-release composition | |
| MX2007015480A (es) | Formulaciones de dosificacion solida de medicamentos narcoticos que tienen adsorcion bucal mejorada. | |
| GEP20074208B (en) | Substituted amides active at the cannabinoid-1 receptor | |
| IL149147A0 (en) | Use of oxcarbazepine for the manufacture of oral dosage form medicament | |
| UA90858C2 (ru) | Композиция с контролируемым высвобождением варденафила | |
| SG167657A1 (en) | Novel medicament compositions based on tiotropium salts and on salmeterol salts | |
| ES2187300A1 (es) | Derivados de sulfonamidas, su preparacion y su aplicacion como medicamentos. | |
| BG66093B1 (bg) | Състави с контролирано освобождаване, съдържащи нимесулид | |
| WO2006072940A3 (en) | Controlled long acting release pharmaceutical preparation for use in the oral cavity | |
| SE9901573D0 (sv) | New compounds | |
| HK1068606A1 (en) | Novel aminobenzoephenones | |
| HUP0301390A2 (hu) | Valzartánt tartalmazó orális gyógyászati készítmény | |
| WO2005082413A3 (en) | Ciclesonide and glycopyrronium combination | |
| SE0102440D0 (sv) | New compound | |
| CA2389032A1 (en) | Preventive or therapeutic agents for inflammatory diseases of intestine | |
| IL179177A (en) | A pharmaceutical product including acyclovir and delivery compound, dosage unit, use of acyclovir in the preparation of the pharmaceutical product, use of the pharmaceutical product in the preparation of a drug and a method for the preparation of the pharmaceutical product | |
| MY137570A (en) | Method for the preparation of a pharmaceutical composition comprising 5-aminosalicyclic acid for use in treatment of ulcerative colitis crohn's disease | |
| TNSN06072A1 (en) | Use of oxcarbazepine for the treatment of diabetic neuropathic pain and the improvement of sleep | |
| SG145717A1 (en) | Composition for releasing a weak base for an extended period of time | |
| CA2385755A1 (en) | Prevention of colorectal cancer | |
| SE9901572D0 (sv) | New compounds |